Poly(A) Signal-Dependent Transcription Termination Occurs through a Conformational Change Mechanism that Does Not Require Cleavage at the Poly(A) Site

Molecular Cell

Volumn 59, Issue 3, 2015, Pages 437-448

  Zhang, Huimin ^a   Rigo, Frank ^b   Martinson, Harold G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA AMANITIN; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; DNA; MESSENGER RNA; PHOSPHODIESTERASE I; POLYADENYLIC ACID; RESTRICTION ENDONUCLEASE; RHO FACTOR; RIBONUCLEASE H; RNA; RNA POLYMERASE II; SPLEEN EXONUCLEASE;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA TEMPLATE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; ESCHERICHIA COLI; GENETIC TRANSCRIPTION; IN VITRO STUDY; NONHUMAN; POLYADENYLATION; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RIBONUCLEASE PROTECTION ASSAY; RNA DEGRADATION; RNA TRANSLATION; SIGNAL TRANSDUCTION; SIMIAN VIRUS 40; TRANSCRIPTION TERMINATION; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECTS; GENETICS; HELA CELL LINE; HUMAN; METABOLISM;

ALPHA-AMANITIN; HELA CELLS; HUMANS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; POLY A; RNA, MESSENGER; TRANSCRIPTION TERMINATION, GENETIC;

EID: 84938741134     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.06.008     Document Type: Article

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