메뉴 건너뛰기




Volumn 28, Issue 3, 2014, Pages 268-276

Paeonol suppresses lipopolysaccharide-induced inflammatory cytokines in macrophage cells and protects mice from lethal endotoxin shock

Author keywords

Cytokines; Lipopolysaccharide; Paeonol; Pathway; Survival

Indexed keywords

ACETOPHENONE DERIVATIVE; CYTOKINE; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE, E COLI O55-B5; NONSTEROID ANTIINFLAMMATORY AGENT; PEONOL;

EID: 84899086164     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/fcp.12019     Document Type: Article
Times cited : (34)

References (41)
  • 1
    • 0001929693 scopus 로고    scopus 로고
    • Cytokines in acute and chronic inflammation
    • Feghali C.A., Wright T.M. Cytokines in acute and chronic inflammation. Front. Biosci. (1997) 2 12-26.
    • (1997) Front. Biosci. , vol.2 , pp. 12-26
    • Feghali, C.A.1    Wright, T.M.2
  • 2
    • 0014888273 scopus 로고
    • Pathology of inflammatory diseases
    • Morson B.C. Pathology of inflammatory diseases. Proc. R. Soc. Med. (1970) 63 63.
    • (1970) Proc. R. Soc. Med. , vol.63 , pp. 63
    • Morson, B.C.1
  • 3
    • 0014886208 scopus 로고
    • Leukocyte function in inflammation: the ingestion, killing, and digestion of microorganisms
    • Cline M.J. Leukocyte function in inflammation: the ingestion, killing, and digestion of microorganisms. Ser. Haematol. (1970) 3 3-16.
    • (1970) Ser. Haematol. , vol.3 , pp. 3-16
    • Cline, M.J.1
  • 4
    • 0028965644 scopus 로고
    • Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin
    • Ulevitch R.J., Tobias P.S. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. (1995) 13 437-457.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 437-457
    • Ulevitch, R.J.1    Tobias, P.S.2
  • 5
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
    • Angus D.C., Linde-Zwirble W.T., Lidicker J., Clermont G., Carcillo J., Pinsky M.R. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit. Care Med. (2001) 29 1303-1310.
    • (2001) Crit. Care Med. , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 6
    • 0030839255 scopus 로고    scopus 로고
    • Pathobiology of lipopolysaccharide
    • Mayeux P.R. Pathobiology of lipopolysaccharide. J. Toxicol. Environ. Health (1997) 51 415-435.
    • (1997) J. Toxicol. Environ. Health , vol.51 , pp. 415-435
    • Mayeux, P.R.1
  • 8
    • 4344716641 scopus 로고    scopus 로고
    • Brazilian sepsis epidemiological study
    • Silva E., Pedro Mde A., Sogayar A.C. et al. Brazilian sepsis epidemiological study. Crit. Care (2004) 8 251-260.
    • (2004) Crit. Care , vol.8 , pp. 251-260
    • Silva, E.1    Pedro Mde, A.2    Sogayar, A.C.3
  • 9
    • 0037426726 scopus 로고    scopus 로고
    • The pathophysiology and treatment of sepsis
    • Hotchkiss R.S., Karl I.E. The pathophysiology and treatment of sepsis. N. Engl. J. Med. (2003) 348 138-150.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 138-150
    • Hotchkiss, R.S.1    Karl, I.E.2
  • 10
    • 40349091729 scopus 로고    scopus 로고
    • Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremony
    • Monneret G., Venet F., Pachot A., Lepape A. Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremony. Mol. Med. (2008) 14 64-78.
    • (2008) Mol. Med. , vol.14 , pp. 64-78
    • Monneret, G.1    Venet, F.2    Pachot, A.3    Lepape, A.4
  • 12
    • 0027920980 scopus 로고
    • Pathogenetic mechanisms of septic shock
    • Parillo J.E. Pathogenetic mechanisms of septic shock. N. Engl. J. Med. (1993) 328 1471-1477.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 1471-1477
    • Parillo, J.E.1
  • 13
    • 77950517957 scopus 로고    scopus 로고
    • Fluorofenidone protects mice from lethal endotoxemia throughthe inhibition of TNF-alpha and IL-1beta release
    • Tang Y., Li B., Wang N. et al. Fluorofenidone protects mice from lethal endotoxemia throughthe inhibition of TNF-alpha and IL-1beta release. Int. Immunopharmacol. (2010) 10 580-583.
    • (2010) Int. Immunopharmacol. , vol.10 , pp. 580-583
    • Tang, Y.1    Li, B.2    Wang, N.3
  • 14
    • 82255180232 scopus 로고    scopus 로고
    • Anti-inflammatory and immunomodulatory effects of paeonia lactiflora pall, a traditional chinese herbal medicine
    • He D.Y., Dai S.M. Anti-inflammatory and immunomodulatory effects of paeonia lactiflora pall, a traditional chinese herbal medicine. Front. Pharmacol. (2011) 2 10.
    • (2011) Front. Pharmacol. , vol.2 , pp. 10
    • He, D.Y.1    Dai, S.M.2
  • 15
    • 0030089941 scopus 로고    scopus 로고
    • Recent progresses in pharmacological and clinical studies of paeonol
    • Zhang L.H., Xiao P.G., Hung Y. Recent progresses in pharmacological and clinical studies of paeonol. Zhongguo Zhong Xi Yi Jie He Za Zhi. (1996) 16 187-190.
    • (1996) Zhongguo Zhong Xi Yi Jie He Za Zhi. , vol.16 , pp. 187-190
    • Zhang, L.H.1    Xiao, P.G.2    Hung, Y.3
  • 16
    • 79955682469 scopus 로고    scopus 로고
    • Effects of total glucosides from paeony (Paeonialactiflora Pall) roots on experimental atherosclerosis in rats
    • Li J., Chen C.X., Shen Y.H. Effects of total glucosides from paeony (Paeonialactiflora Pall) roots on experimental atherosclerosis in rats. J. Ethnopharmacol. (2011) 135 469-475.
    • (2011) J. Ethnopharmacol. , vol.135 , pp. 469-475
    • Li, J.1    Chen, C.X.2    Shen, Y.H.3
  • 17
    • 0029842676 scopus 로고    scopus 로고
    • Endothelium-dependent vasodilator effect of extract prepared from the roots of Paeonia lactiflora on isolated rat aorta
    • Goto H., Shimada Y., Akechi Y., Kohta K., Hattori M., Terasawa K. Endothelium-dependent vasodilator effect of extract prepared from the roots of Paeonia lactiflora on isolated rat aorta. Planta Med. (1996) 62 436-439.
    • (1996) Planta Med. , vol.62 , pp. 436-439
    • Goto, H.1    Shimada, Y.2    Akechi, Y.3    Kohta, K.4    Hattori, M.5    Terasawa, K.6
  • 18
    • 58149119641 scopus 로고    scopus 로고
    • Ivermectin inhibits LPS-induced production of inflammatory cytokines and improves LPS-induced survival in mice
    • Zhang X.M., Song Y., Ci X.X. et al. Ivermectin inhibits LPS-induced production of inflammatory cytokines and improves LPS-induced survival in mice. Inflamm. Res. (2008) 57 524-529.
    • (2008) Inflamm. Res. , vol.57 , pp. 524-529
    • Zhang, X.M.1    Song, Y.2    Ci, X.X.3
  • 19
    • 38349110194 scopus 로고    scopus 로고
    • Modulation of LPS stimulated NF-kappaB mediated Nitric Oxide production by PKCepsilon and JAK2 in RAW macrophages
    • Jones E., Adcock I.M., Ahmed B.Y. et al. Modulation of LPS stimulated NF-kappaB mediated Nitric Oxide production by PKCepsilon and JAK2 in RAW macrophages. J. Inflamm. (2007) 4 23-31.
    • (2007) J. Inflamm. , vol.4 , pp. 23-31
    • Jones, E.1    Adcock, I.M.2    Ahmed, B.Y.3
  • 20
    • 0027257328 scopus 로고
    • Modulation of adjuvant arthritis by endogenousnitric oxide
    • Ialenti A., Moncada S., Di Rosa M. Modulation of adjuvant arthritis by endogenousnitric oxide. Br. J. Pharmacol. (1993) 110 701-706.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 701-706
    • Ialenti, A.1    Moncada, S.2    Di Rosa, M.3
  • 21
    • 0026787367 scopus 로고
    • The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia
    • Cunha F.Q., Poole S., Lorenzetti B.B., Ferreira S.H. The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia. Br. J. Pharmacol. (1992) 107 660-664.
    • (1992) Br. J. Pharmacol. , vol.107 , pp. 660-664
    • Cunha, F.Q.1    Poole, S.2    Lorenzetti, B.B.3    Ferreira, S.H.4
  • 22
    • 1842607467 scopus 로고    scopus 로고
    • Innate immunity and Toll-like receptors: clinical implications of basic science research
    • Abreu M.T., Arditi M. Innate immunity and Toll-like receptors: clinical implications of basic science research. J. Pediatr. (2004) 144 421-429.
    • (2004) J. Pediatr. , vol.144 , pp. 421-429
    • Abreu, M.T.1    Arditi, M.2
  • 23
    • 0029928366 scopus 로고    scopus 로고
    • Tumor necrosis factors: developments during the last decade
    • Aggarwal B.B., Natarajan K. Tumor necrosis factors: developments during the last decade. Eur. Cytokine Netw. (1996) 7 93-124.
    • (1996) Eur. Cytokine Netw. , vol.7 , pp. 93-124
    • Aggarwal, B.B.1    Natarajan, K.2
  • 25
    • 0028815553 scopus 로고
    • Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance
    • Berg D.J., Kuhn R., Rajewsky K. et al. Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance. J. Clin. Invest. (1995) 96 2339-2347.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2339-2347
    • Berg, D.J.1    Kuhn, R.2    Rajewsky, K.3
  • 26
    • 0027478367 scopus 로고
    • Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia
    • Ge'rard C., Bruyns C., Marchant A. et al. Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia. J. Exp. Med. (1993) 177 547-550.
    • (1993) J. Exp. Med. , vol.177 , pp. 547-550
    • Ge'rard, C.1    Bruyns, C.2    Marchant, A.3
  • 27
    • 0030025282 scopus 로고    scopus 로고
    • Interleukin-10 attenuates the release of proinflammatory cytokines but depresses splenocyte functions in murine endotoxemia
    • Ertel W., Keel M., Steckholzer U., Ungethüm U., Trentz O. Interleukin-10 attenuates the release of proinflammatory cytokines but depresses splenocyte functions in murine endotoxemia. Arch. Surg. (1996) 131 51-56.
    • (1996) Arch. Surg. , vol.131 , pp. 51-56
    • Ertel, W.1    Keel, M.2    Steckholzer, U.3    Ungethüm, U.4    Trentz, O.5
  • 28
    • 14644414825 scopus 로고    scopus 로고
    • New insights into the molecular mechanism of interleukin-10-mediated immunosuppression
    • Grutz G. New insights into the molecular mechanism of interleukin-10-mediated immunosuppression. J. Leukoc. Biol. (2005) 77 3-15.
    • (2005) J. Leukoc. Biol. , vol.77 , pp. 3-15
    • Grutz, G.1
  • 29
    • 70349781839 scopus 로고    scopus 로고
    • Paeonol from Paeonia suffruticosa prevents TNF-a-induced monocytic cell adhesion to rat aortic endothelial cells by suppression of VCAM-1 expression
    • Pan L.L., Dai M. Paeonol from Paeonia suffruticosa prevents TNF-a-induced monocytic cell adhesion to rat aortic endothelial cells by suppression of VCAM-1 expression. Phytomedicine (2009) 16 1027-1032.
    • (2009) Phytomedicine , vol.16 , pp. 1027-1032
    • Pan, L.L.1    Dai, M.2
  • 30
    • 4043109947 scopus 로고    scopus 로고
    • Diverse regulation of NF-kappaB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver
    • Romics L., Kodys K., Dolganiuc A. et al. Diverse regulation of NF-kappaB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver. Hepatology (2004) 40 376-385.
    • (2004) Hepatology , vol.40 , pp. 376-385
    • Romics, L.1    Kodys, K.2    Dolganiuc, A.3
  • 31
    • 79960315345 scopus 로고    scopus 로고
    • Cornuside suppresses lipopolysaccharide-induced inflammatory mediators by inhibiting Nuclear Factor-Kappa B activation in RAW 264.7 Macrophages
    • Choi Y.H., Jin G.Y., Li G.A., Yan A.H. Cornuside suppresses lipopolysaccharide-induced inflammatory mediators by inhibiting Nuclear Factor-Kappa B activation in RAW 264.7 Macrophages. Biol. Pharm. Bull. (2011) 34 959-966.
    • (2011) Biol. Pharm. Bull. , vol.34 , pp. 959-966
    • Choi, Y.H.1    Jin, G.Y.2    Li, G.A.3    Yan, A.H.4
  • 32
    • 33644976705 scopus 로고    scopus 로고
    • MAP kinases in immune responses
    • Zhang Y.L., Dong C. MAP kinases in immune responses. Cell. Mol. Immunol. (2005) 2 20-27.
    • (2005) Cell. Mol. Immunol. , vol.2 , pp. 20-27
    • Zhang, Y.L.1    Dong, C.2
  • 33
    • 65449182356 scopus 로고    scopus 로고
    • Inhibition of LPS-induced iNOS, COX-2 and inflammatory mediator expression by paeonol through the MAPKs inactivation in RAW 264.7 cells
    • Chae H.S., Kang O.H., Lee Y.S. et al. Inhibition of LPS-induced iNOS, COX-2 and inflammatory mediator expression by paeonol through the MAPKs inactivation in RAW 264.7 cells. Am. J. Chin. Med. (2009) 37 181-194.
    • (2009) Am. J. Chin. Med. , vol.37 , pp. 181-194
    • Chae, H.S.1    Kang, O.H.2    Lee, Y.S.3
  • 34
    • 42649116083 scopus 로고    scopus 로고
    • A genome-wide microarray analysis reveals anti-inflammatory target genes of paeonol in macrophages
    • Huang H., Chang E.J., Lee Y., Kim J.S., Kang S.S., Kim H.H. A genome-wide microarray analysis reveals anti-inflammatory target genes of paeonol in macrophages. Inflamm. Res. (2008) 57 189-198.
    • (2008) Inflamm. Res. , vol.57 , pp. 189-198
    • Huang, H.1    Chang, E.J.2    Lee, Y.3    Kim, J.S.4    Kang, S.S.5    Kim, H.H.6
  • 35
    • 84863275751 scopus 로고    scopus 로고
    • Anti-inflammatory and anticoagulative effects of paeonol on LPS-induced acute lung injury in rats
    • Fu P.K., Wu C.L., Tsai T.H., Hsieh C.L. Anti-inflammatory and anticoagulative effects of paeonol on LPS-induced acute lung injury in rats. Evid. Based Complement. Alternat. Med. (2012) 2012 837513.
    • (2012) Evid. Based Complement. Alternat. Med. , vol.2012 , pp. 837513
    • Fu, P.K.1    Wu, C.L.2    Tsai, T.H.3    Hsieh, C.L.4
  • 36
    • 35748967869 scopus 로고    scopus 로고
    • Prodigiosin isolated from Hahella chejuensis suppresses lipopolysaccharide-induced NO production by inhibiting p38 MAPK, JNK and NF-κBactivation in murine peritoneal macrophages
    • Huh J.E., Yim J.H., Lee H.K., Moon E.Y., Rhee D.K., Pyo S. Prodigiosin isolated from Hahella chejuensis suppresses lipopolysaccharide-induced NO production by inhibiting p38 MAPK, JNK and NF-κBactivation in murine peritoneal macrophages. Int. Immunopharmacol. (2007) 7 1825-1833.
    • (2007) Int. Immunopharmacol. , vol.7 , pp. 1825-1833
    • Huh, J.E.1    Yim, J.H.2    Lee, H.K.3    Moon, E.Y.4    Rhee, D.K.5    Pyo, S.6
  • 37
    • 84861199459 scopus 로고    scopus 로고
    • Sepsis: something old, something new, and a systems view
    • e1-11.
    • Namas R., Zamora R., Namas R. et al. Sepsis: something old, something new, and a systems view. J. Crit. Care (2012) 27 314.e1-11.
    • (2012) J. Crit. Care , vol.27 , pp. 314
    • Namas, R.1    Zamora, R.2    Namas, R.3
  • 38
    • 48049087623 scopus 로고    scopus 로고
    • Interleukin-6 and procalcitonin in children with sepsis and septic shock
    • Fioretto J.R., Martin J.G., Kurokawa C.S. et al. Interleukin-6 and procalcitonin in children with sepsis and septic shock. Cytokine (2008) 43 160-161.
    • (2008) Cytokine , vol.43 , pp. 160-161
    • Fioretto, J.R.1    Martin, J.G.2    Kurokawa, C.S.3
  • 39
    • 0027410497 scopus 로고
    • The MAP kinase cascade is essential for diverse signal transduction pathway
    • Nishida E., Gotoh Y. The MAP kinase cascade is essential for diverse signal transduction pathway. Trends Biochem. Sci. (1993) 18 128-131.
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 128-131
    • Nishida, E.1    Gotoh, Y.2
  • 40
    • 0005261734 scopus 로고
    • Rapid stimulation by insulin of a serine threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubuleassociated protein 2 in vitro
    • Ray L.B., Sturgill T.W. Rapid stimulation by insulin of a serine threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubuleassociated protein 2 in vitro. Proc. Natl Acad. Sci. (1987) 84 1502-1506.
    • (1987) Proc. Natl Acad. Sci. , vol.84 , pp. 1502-1506
    • Ray, L.B.1    Sturgill, T.W.2
  • 41
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation
    • Marshall C.J. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell (1995) 80 179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.