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Volumn 10, Issue 10, 2015, Pages 2237-2245

DNA Encoded Library Selections and Insights Provided by Computational Simulations

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ASSOCIATION CONSTANT; CONTROLLED STUDY; DNA LIBRARY; GENETIC SELECTION; HIGH THROUGHPUT SEQUENCING; MATHEMATICAL MODEL; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; SIMULATION; CHEMISTRY; COMBINATORIAL CHEMISTRY; COMPUTER SIMULATION; MOLECULAR LIBRARY; THEORETICAL MODEL;

EID: 84944754852     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.5b00378     Document Type: Article
Times cited : (63)

References (23)
  • 1
    • 84939823002 scopus 로고    scopus 로고
    • Reported applications of DNA-encoded library chemistry
    • (Goodnow, R. A. Jr, Ed.), pp, Wiley, New York
    • Ottl, J. (2014) Reported applications of DNA-encoded library chemistry, In Handbook for DNA-Encoded Chemistry (Goodnow, R. A., Jr, Ed.), pp 319-347, Wiley, New York.
    • (2014) Handbook for DNA-Encoded Chemistry , pp. 319-347
    • Ottl, J.1
  • 2
    • 77952543008 scopus 로고    scopus 로고
    • Selecting chemicals: The emerging utility of DNA-encoded libraries
    • Clark, M. A. (2010) Selecting chemicals: the emerging utility of DNA-encoded libraries Curr. Opin. Chem. Biol. 14, 396-403 10.1016/j.cbpa.2010.02.017
    • (2010) Curr. Opin. Chem. Biol. , vol.14 , pp. 396-403
    • Clark, M.A.1
  • 5
    • 84923182115 scopus 로고    scopus 로고
    • Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation
    • Wichert, M., Krall, N., Decurtins, W., Franzini, R. M., Pretto, F., Schneider, P., Neri, D., and Scheuermann, J. (2015) Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation Nat. Chem. 7, 241-249 10.1038/nchem.2158
    • (2015) Nat. Chem. , vol.7 , pp. 241-249
    • Wichert, M.1    Krall, N.2    Decurtins, W.3    Franzini, R.M.4    Pretto, F.5    Schneider, P.6    Neri, D.7    Scheuermann, J.8
  • 7
    • 84897459461 scopus 로고    scopus 로고
    • Application of encoded library technology (ELT) to a protein-protein interaction target: Discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists
    • Kollmann, C. S., Bai, X., Tsai, C.-H., Yang, H., Lind, K. E., Skinner, S. R., Zhu, Z., Israel, D. I., Cuozzo, J. W., and Morgan, B. A. (2014) Application of encoded library technology (ELT) to a protein-protein interaction target: Discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists Bioorg. Med. Chem. 22, 2353-2365 10.1016/j.bmc.2014.01.050
    • (2014) Bioorg. Med. Chem. , vol.22 , pp. 2353-2365
    • Kollmann, C.S.1    Bai, X.2    Tsai, C.-H.3    Yang, H.4    Lind, K.E.5    Skinner, S.R.6    Zhu, Z.7    Israel, D.I.8    Cuozzo, J.W.9    Morgan, B.A.10
  • 8
    • 84866910785 scopus 로고    scopus 로고
    • Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT)
    • Deng, H., O'Keefe, H., Davie, C. P., Lind, K. E., Acharya, R. A., Franklin, G. J., Larkin, J., Matico, R., Neeb, M., and Thompson, M. M. (2012) Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT) J. Med. Chem. 55, 7061-7079 10.1021/jm300449x
    • (2012) J. Med. Chem. , vol.55 , pp. 7061-7079
    • Deng, H.1    O'Keefe, H.2    Davie, C.P.3    Lind, K.E.4    Acharya, R.A.5    Franklin, G.J.6    Larkin, J.7    Matico, R.8    Neeb, M.9    Thompson, M.M.10
  • 11
    • 84921647505 scopus 로고    scopus 로고
    • Novel encoding methods for DNA-templated chemical libraries
    • Li, G., Zheng, W., Liu, Y., and Li, X. (2015) Novel encoding methods for DNA-templated chemical libraries Curr. Opin. Chem. Biol. 26, 25-33 10.1016/j.cbpa.2015.01.004
    • (2015) Curr. Opin. Chem. Biol. , vol.26 , pp. 25-33
    • Li, G.1    Zheng, W.2    Liu, Y.3    Li, X.4
  • 12
    • 84906545678 scopus 로고    scopus 로고
    • A DNA- templated synthesis of encoded small molecules by DNA self- assembly
    • Cao, C., Zhao, P., Li, Z., Chen, Z., Huang, Y., Bai, Y., and Li, X. (2014) A DNA- templated synthesis of encoded small molecules by DNA self- assembly Chem. Commun. 50 (75) 10997-10999 10.1039/C4CC03380A
    • (2014) Chem. Commun. , vol.50 , Issue.75 , pp. 10997-10999
    • Cao, C.1    Zhao, P.2    Li, Z.3    Chen, Z.4    Huang, Y.5    Bai, Y.6    Li, X.7
  • 13
    • 84939789723 scopus 로고    scopus 로고
    • Exercises in the synthesis of DNA-Encoded libraries, Handbook for DNA-Encoded Chemistry
    • (Goodnow, R. A. Jr, Ed.), pp, Wiley, NJ
    • Creaser, S. P. and Acharya, R. A. (2014) Exercises in the synthesis of DNA-Encoded libraries, Handbook for DNA-Encoded Chemistry, In Handbook for DNA-Encoded Chemistry (Goodnow, R. A., Jr, Ed.), pp 123-152, Wiley, NJ.
    • (2014) Handbook for DNA-Encoded Chemistry , pp. 123-152
    • Creaser, S.P.1    Acharya, R.A.2
  • 14
    • 4544357020 scopus 로고    scopus 로고
    • DNA-Templated Organic Synthesis: Nature's Strategy for Controlling Chemical Reactivity Applied to Synthetic Molecules
    • Li, X. and Liu, D. R. (2004) DNA-Templated Organic Synthesis: Nature's Strategy for Controlling Chemical Reactivity Applied to Synthetic Molecules Angew. Chem., Int. Ed. 43, 4848-4870 10.1002/anie.200400656
    • (2004) Angew. Chem., Int. Ed. , vol.43 , pp. 4848-4870
    • Li, X.1    Liu, D.R.2
  • 15
    • 84939823003 scopus 로고    scopus 로고
    • DNA-Compatible Chemistry
    • (Goodnow, R. A. Jr, Ed.), pp, Wiley, NJ
    • Luk, K.-C. and Satz, A. L. (2014) DNA-Compatible Chemistry, In Handbook for DNA-Encoded Chemistry (Goodnow, R. A., Jr, Ed.), pp 67-98, Wiley, NJ.
    • (2014) Handbook for DNA-Encoded Chemistry , pp. 67-98
    • Luk, K.-C.1    Satz, A.L.2
  • 17
    • 84939823004 scopus 로고    scopus 로고
    • Foundations of a DNA-Encoded Library (DEL)
    • (Goodnow, R. A. Jr, Ed.), pp, Wiley, NJ
    • Satz, A. L. (2014) Foundations of a DNA-Encoded Library (DEL), In Handbook for DNA-Encoded Chemistry (Goodnow, R. A., Jr, Ed.), pp 99-122, Wiley, NJ.
    • (2014) Handbook for DNA-Encoded Chemistry , pp. 99-122
    • Satz, A.L.1
  • 20
    • 84923098539 scopus 로고    scopus 로고
    • Screening Large Compound Collections
    • (Goodnow, R. A. Jr, Ed.), pp, Wiley, New York
    • Hale, S. P. (2014) Screening Large Compound Collections, In Handbook for DNA-Encoded Chemistry (Goodnow, R. A., Jr, Ed.), pp 281-318, Wiley, New York.
    • (2014) Handbook for DNA-Encoded Chemistry , pp. 281-318
    • Hale, S.P.1
  • 21
    • 84922227281 scopus 로고    scopus 로고
    • Characterization of DNA-Conjugated Compounds Using a Regenerable Chip
    • Lin, W., Reddavide, F. V., Uzunova, V., Gür, F. N., and Zhang, Y. (2015) Characterization of DNA-Conjugated Compounds Using a Regenerable Chip Anal. Chem. 87, 864-868 10.1021/ac503960z
    • (2015) Anal. Chem. , vol.87 , pp. 864-868
    • Lin, W.1    Reddavide, F.V.2    Uzunova, V.3    Gür, F.N.4    Zhang, Y.5
  • 23
    • 78049403279 scopus 로고    scopus 로고
    • Ligand binding assays at equilibrium: Validation and interpretation
    • Hulme, E. C. and Trevethick, M. A. (2010) Ligand binding assays at equilibrium: validation and interpretation Br. J. Pharmacol. 161, 1219-1237 10.1111/j.1476-5381.2009.00604.x
    • (2010) Br. J. Pharmacol. , vol.161 , pp. 1219-1237
    • Hulme, E.C.1    Trevethick, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.