IFNγ-TNFα-IL2-MIP1α-CD107a+PRF1+ CD8 pp65-Specific T-Cell Response Is Independently Associated with Time to Death in Elderly Humans

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 70, Issue 10, 2014, Pages 1210-1218

  Ferrando Martínez, Sara ^a,b,c,d   Ruiz Mateos, Ezequiel ^d   Casazza, Joseph P ^e   De Pablo Bernal, Rebeca S ^d   Dominguez Molina, Beatriz ^d   Muñoz Fernández, M Ángeles ^a,b,c   Delgado, Juan ^f   De La Rosa, Rafael ^f   Solana, Rafael ^g   Koup, Richard A ^e   Leal, Manuel ^d  

^a HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^c BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^d HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^f Hospital San Juan de Dios de Santurce   (Spain)

^g HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

Author keywords

Aging; CMV; CMV specific T cell response; Mortality; Perforin

Indexed keywords

C REACTIVE PROTEIN; CARRIER PROTEIN; CYTOMEGALOVIRUS MATRIX PROTEIN 65KDA; GAMMA INTERFERON; INTERLEUKIN 2; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MATRIX PROTEIN; PERFORIN; PHOSPHOPROTEIN; PP5644 PROTEIN, HUMAN; PRF1 PROTEIN, HUMAN; TNF PROTEIN, HUMAN; TUMOR NECROSIS FACTOR; TUMOR SUPPRESSOR PROTEIN;

AGED; CAUSE OF DEATH; CD8+ T LYMPHOCYTE; CYTOMEGALOVIRUS INFECTION; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOLOGY; MALE; MIDDLE AGED; MORTALITY; PHENOTYPE; RISK FACTOR; SURVIVAL ANALYSIS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; C-REACTIVE PROTEIN; CARRIER PROTEINS; CAUSE OF DEATH; CD8-POSITIVE T-LYMPHOCYTES; CYTOMEGALOVIRUS INFECTIONS; FEMALE; FLOW CYTOMETRY; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-2; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; MALE; MIDDLE AGED; PERFORIN; PHENOTYPE; PHOSPHOPROTEINS; RISK FACTORS; SURVIVAL ANALYSIS; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEINS; VIRAL MATRIX PROTEINS;

EID: 84944686937     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glu171     Document Type: Article

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