MicroRNA-346 functions as an oncogene in cutaneous squamous cell carcinoma

Tumor Biology

Volumn 37, Issue 2, 2016, Pages 2765-2771

  Chen, Bin ^a,b   Pan, Wenyan ^b   Lin, Xiaoxi ^a   Hu, Zhenzhen ^c   Jin, Yunbo ^a   Chen, Hui ^a   Ma, Gang ^a   Qiu, Yajing ^a   Chang, Lei ^a   Hua, Chen ^a   Zou, Yun ^a   Gao, Yang ^a   Ying, Hanru ^a   Lv, Dongze ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b GUANGXI MEDICAL UNIVERSITY   (China)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Cutaneous squamous cell carcinoma; miR 346; Oncogene; SRCIN1

Indexed keywords

GLYCOPROTEIN GP 140; MICRORNA; MICRORNA 346; SRCIN1 PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; MESSENGER RNA; MIRN346 MICRORNA, HUMAN; SNIP PROTEIN, HUMAN; VESICULAR TRANSPORT ADAPTOR PROTEIN;

3' UNTRANSLATED REGION; ARTICLE; CANCER CELL LINE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SKIN CARCINOMA; UPREGULATION; WESTERN BLOTTING; WOUND HEALING; CELL MOTION; GENE EXPRESSION REGULATION; GENETICS; KERATINOCYTE; PATHOLOGY; SKIN TUMOR; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

3' UNTRANSLATED REGIONS; ADAPTOR PROTEINS, VESICULAR TRANSPORT; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KERATINOCYTES; MICRORNAS; ONCOGENES; RNA, MESSENGER; SKIN NEOPLASMS;

EID: 84944683266     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-4046-2     Document Type: Article

References (43)

1. Wang N, Xu ZW, Wang KH. Systematical analysis of cutaneous squamous cell carcinoma network of microRNAs, transcription factors, and target and host genes. Asian Pac J Cancer Prev: APJCP. 2014;15:10355–61.
2. Greenberg ES, Chong KK, Huynh KT, Tanaka R, Hoon DS. Epigenetic biomarkers in skin cancer. Cancer Lett. 2014;342:170–7.
3. Gastaldi C, Bertero T, Xu N, Bourget-Ponzio I, Lebrigand K, Fourre S, et al. miR-193b/365a cluster controls progression of epidermal squamous cell carcinoma. Carcinogenesis. 2014;35:1110–20.
4. Bruegger C, Kempf W, Spoerri I, Arnold AW, Itin PH, Burger B. MicroRNA expression differs in cutaneous squamous cell carcinomas and healthy skin of immunocompetent individuals. Exp Dermatol. 2013;22:426–8.
5. Zhou M, Zhou L, Zheng L, Guo L, Wang Y, Liu H, et al. miR-365 promotes cutaneous squamous cell carcinoma (CSCC) through targeting nuclear factor I/B (NFIB). PLoS ONE. 2014;9, e100620.
6. Ning MS, Andl T. Custodians of the transcriptome: how microRNAs guard stemness in squamous epithelia. Stem Cells. 2014;33(4):1047–54.
7. Sand M, Skrygan M, Georgas D, Sand D, Hahn SA, Gambichler T, et al. Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma. J Dermatol Sci. 2012;68:119–26.
8. Ning MS, Kim AS, Prasad N, Levy SE, Zhang H, Andl T. Characterization of the Merkel cell carcinoma miRNome. J Skin Cancer. 2014;2014, 289548.
9. Yamane K, Jinnin M, Etoh T, Kobayashi Y, Shimozono N, Fukushima S, et al. Down-regulation of miR-124/-214 in cutaneous squamous cell carcinoma mediates abnormal cell proliferation via the induction of ERK. J Mol Med (Berl). 2013;91:69–81.
10. Kanitz A, Imig J, Dziunycz PJ, Primorac A, Galgano A, Hofbauer GF, et al. The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinoma. PLoS ONE. 2012;7, e49568.
11. Wang A, Landen NX, Meisgen F, Lohcharoenkal W, Stahle M, Sonkoly E, et al. MicroRNA-31 is overexpressed in cutaneous squamous cell carcinoma and regulates cell motility and colony formation ability of tumor cells. PLoS ONE. 2014;9, e103206.
12. Hameetman L, Commandeur S, Bavinck JN, Wisgerhof HC, de Gruijl FR, Willemze R, et al. Molecular profiling of cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients. BMC Cancer. 2013;13:58.
13. Yu X, Li Z. MicroRNAs regulate vascular smooth muscle cell functions in atherosclerosis (review). Int J Mol Med. 2014;34:923–33.
14. Li Z, Lei H, Luo M, Wang Y, Dong L, Ma Y, et al. DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer. Gastric Cancer. 2015;18:43–54.
15. Li Z, Yu X, Shen J, Jiang Y. MicroRNA dysregulation in uveal melanoma: a new player enters the game. Oncotarget. 2015;6(7):4562–8.
16. Liu G, Liu R, Li Q, Tang X, Yu M, Li X, et al. Identification of microRNAs in wool follicles during anagen, catagen, and telogen phases in Tibetan sheep. PLoS ONE. 2013;8, e77801.
17. Li Z, Yu X, Shen J, Chan MT, Wu WK. MicroRNA in intervertebral disc degeneration. Cell Prolif. 2015;48(3):278–83.
18. Li Z, Yu X, Wang Y, Shen J, Wu WK, Liang J, et al. By downregulating TIAM1 expression, microRNA-329 suppresses gastric cancer invasion and growth. Oncotarget. 2014;6(19):17559–69.
19. Yu X, Li Z, Shen J, Wu WK, Liang J, Weng X, et al. MicroRNA-10b promotes nucleus pulposus cell proliferation through RhoC-Akt pathway by targeting HOXD10 in intervertebral disc degeneration. PLoS ONE. 2013;8, e83080.
20. Rao SA, Arimappamagan A, Pandey P, Santosh V, Hegde AS, Chandramouli BA, et al. miR-219-5p inhibits receptor tyrosine kinase pathway by targeting EGFR in glioblastoma. PLoS ONE. 2013;8, e63164.
21. Wu X, Weng L, Li X, Guo C, Pal SK, Jin JM, et al. Identification of a 4-microRNA signature for clear cell renal cell carcinoma metastasis and prognosis. PLoS ONE. 2012;7, e35661.
22. Li BS, Zhao YL, Guo G, Li W, Zhu ED, Luo X, et al. Plasma microRNAs, miR-223, miR-21 and miR-218, as novel potential biomarkers for gastric cancer detection. PLoS ONE. 2012;7, e41629.
23. Jung CJ, Iyengar S, Blahnik KR, Ajuha TP, Jiang JX, Farnham PJ, et al. Epigenetic modulation of miR-122 facilitates human embryonic stem cell self-renewal and hepatocellular carcinoma proliferation. PLoS ONE. 2011;6, e27740.
24. Vrba L, Munoz-Rodriguez JL, Stampfer MR, Futscher BW. Mirna gene promoters are frequent targets of aberrant DNA methylation in human breast cancer. PLoS ONE. 2013;8, e54398.
25. Denoyelle C, Lambert B, Meryet-Figuiere M, Vigneron N, Brotin E, Lecerf C, et al. miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation. Cell Death Dis. 2014;5, e1445.
26. Rao PK, Missiaglia E, Shields L, Hyde G, Yuan B, Shepherd CJ, et al. Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cells. FASEB J. 2010;24:3427–37.
27. Worley LA, Long MD, Onken MD, Harbour JW. Micro-RNAs associated with metastasis in uveal melanoma identified by multiplexed microarray profiling. Melanoma Res. 2008;18:184–90.
28. Yu X, Li Z, Liu J. MiRNAs in primary cutaneous lymphomas. Cell Prolif. 2015;48(3):271–7.
29. Li Z, Yu X, Shen J, Wu WK, Chan MT. MicroRNA expression and its clinical implications in Ewing’s sarcoma. Cell Prolif. 2015;48:1–6.
30. Bemis LT, Chen R, Amato CM, Classen EH, Robinson SE, Coffey DG, et al. MicroRNA-137 targets microphthalmia-associated transcription factor in melanoma cell lines. Cancer Res. 2008;68:1362–8.
31. Langevin SM, Stone RA, Bunker CH, Grandis JR, Sobol RW, Taioli E. MicroRNA-137 promoter methylation in oral rinses from patients with squamous cell carcinoma of the head and neck is associated with gender and body mass index. Carcinogenesis. 2010;31:864–70.
32. Alsaleh G, Suffert G, Semaan N, Juncker T, Frenzel L, Gottenberg JE, et al. Bruton’s tyrosine kinase is involved in miR-346-related regulation of IL-18 release by lipopolysaccharide-activated rheumatoid fibroblast-like synoviocytes. J Immunol. 2009;182:5088–97.
33. Chen Y, Du J, Zhang Z, Liu T, Shi Y, Ge X, et al. MicroRNA-346 mediates tumor necrosis factor alpha-induced downregulation of gut epithelial vitamin d receptor in inflammatory bowel diseases. Inflamm Bowel Dis. 2014;20:1910–8.
34. + T cells in the pathogenesis of Graves’ disease. Endocrine. 2015;49(3):752–60.
35. Semaan N, Frenzel L, Alsaleh G, Suffert G, Gottenberg JE, Sibilia J, et al. miR-346 controls release of TNF-alpha protein and stability of its mRNA in rheumatoid arthritis via tristetraprolin stabilization. PLoS ONE. 2011;6, e19827.
36. Xiao J, Liu D, Jiao W, Guo J, Wang X, Zhang X, et al. Effects of microRNA-346 on epithelial-mesenchymal transition in mouse podocytes. Gene. 2015;560:195–9.
37. Cabodi S, del Pilar C-LM, Di Stefano P, Defilippi P. Integrin signalling adaptors: not only figurants in the cancer story. Nat Rev Cancer. 2010;10:858–70.
38. Repetto D, Aramu S, Boeri Erba E, Sharma N, Grasso S, Russo I, et al. Mapping of p140Cap phosphorylation sites: the EPLYA and EGLYA motifs have a key role in tyrosine phosphorylation and Csk binding, and are substrates of the Abl kinase. PLoS ONE. 2013;8, e54931.
39. Yamauchi M, Sudo K, Ito H, Iwamoto I, Morishita R, Murai T, et al. Localization of multidomain adaptor proteins, p140Cap and vinexin, in the pancreatic islet of a spontaneous diabetes mellitus model, Otsuka Long-Evans Tokushima fatty rats. Med Mol Morphol. 2013;46:41–8.
40. Sharma N, Repetto D, Aramu S, Grasso S, Russo I, Fiorentino A, et al. Identification of two regions in the p140Cap adaptor protein that retain the ability to suppress tumor cell properties. Am J Cancer Res. 2013;3:290–301.
41. Di Stefano P, Damiano L, Cabodi S, Aramu S, Tordella L, Praduroux A, et al. p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity. EMBO J. 2007;26:2843–55.
42. Cao M, Hou D, Liang H, Gong F, Wang Y, Yan X, et al. miR-150 promotes the proliferation and migration of lung cancer cells by targeting SRC kinase signalling inhibitor 1. Eur J Cancer. 2014;50(5):1013–24.
43. Xu X, Wang W, Su N, Zhu X, Yao J, Gao W, et al. miR-374a promotes cell proliferation, migration and invasion by targeting SRCIN1 in gastric cancer. FEBS Lett. 2015;589:407–13.