Enhanced functional activity of the cannabinoid type-1 receptor mediates adolescent behavior

Journal of Neuroscience

Volumn 35, Issue 41, 2015, Pages 13975-13988

  Schneider, Miriam ^a   Kasanetz, Fernando ^b,c   Lynch, Diane L ^d   Friemel, Chris M ^a   Lassalle, Olivier ^e,f,g   Hurst, Dow P ^d   Steindel, Frauke ^h   Monory, Krisztina ^h   Schäfer, Carola ^a,i   Miederer, Isabelle ^h   Leweke, F Markus ^a   Schreckenberger, Mathias ^h   Lutz, Beat ^h   Reggio, Patricia H ^d   Manzoni, Olivier J ^e,f,g   Spanagel, Rainer ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b INSTITUT FRANÇOIS MAGENDIE   (France)

^c UNIVERSITÉ DE BORDEAUX   (France)

^d UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

^e INSERM   (France)

^f AIX MARSEILLE UNIVERSITY   (France)

^g Turing Center for Living Systems CENTURI Aix Marseille University   (France)

^h UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

ⁱ UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Adolescence; CB1 receptor; Endocannabinoids; ENU mutagenesis; Reward processing; Risk seeking

Indexed keywords

CANNABINOID 1 RECEPTOR; COCAINE; ENDOCANNABINOID; CANNABINOID RECEPTOR ANTAGONIST; CNR1 PROTEIN, MOUSE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); SULFUR;

ADOLESCENT; ADOLESCENT BEHAVIOR; ADULT; ARTICLE; CAPILLARY ELECTROPHORESIS; COMPUTER MODEL; CONTROLLED STUDY; EXPERIMENTAL DESIGN; FUNCTIONAL ASSESSMENT; GAIN OF FUNCTION MUTATION; HIGH RISK BEHAVIOR; IMPULSIVENESS; LIQUID SCINTILLATION COUNTING; MALE; MISSENSE MUTATION; MOLECULAR DYNAMICS; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOACTIVITY; SENSITIVITY ANALYSIS; SIGNAL PROCESSING; SIGNAL TRANSDUCTION; WESTERN BLOTTING; AGE; ANIMAL; ANIMAL BEHAVIOR; ANIMAL MODEL; BRAIN; CORPUS STRIATUM; CYTOLOGY; DIAGNOSTIC IMAGING; DRUG EFFECTS; EXPLORATORY BEHAVIOR; FISCHER 344 RAT; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; IN VITRO STUDY; MAZE TEST; METABOLISM; MUTATION; PHYSIOLOGY; RAT; SCINTISCANNING; SOCIAL BEHAVIOR; TRANSGENIC RAT;

ADOLESCENT; ADOLESCENT BEHAVIOR; AGE FACTORS; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CANNABINOID RECEPTOR ANTAGONISTS; COCAINE; CORPUS STRIATUM; ENDOCANNABINOIDS; EXPLORATORY BEHAVIOR; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; IN VITRO TECHNIQUES; MALE; MAZE LEARNING; MODELS, ANIMAL; MUTATION; RADIONUCLIDE IMAGING; RATS; RATS, INBRED F344; RATS, TRANSGENIC; RECEPTOR, CANNABINOID, CB1; RISK-TAKING; SOCIAL BEHAVIOR; SULFUR ISOTOPES;

EID: 84944620721     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1937-15.2015     Document Type: Article

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