메뉴 건너뛰기




Volumn 226, Issue 3, 2015, Pages G1-G10

Tracing lipid metabolism: The value of stable isotopes

Author keywords

Cholesterol; Fatty acids; Lipoproteins; Stable isotopes; Tracers

Indexed keywords

2 OXOISOCAPROIC ACID; CARBON; CARBON 13; CHOLESTEROL; CHYLOMICRON; FATTY ACID; GLYCEROL; GLYCEROL KINASE; HYDROGEN; NITROGEN; NITROGEN 15; OXYGEN; OXYGEN 17; OXYGEN 18; STABLE ISOTOPE; TRACER; VERY LOW DENSITY LIPOPROTEIN; HORMONE; ISOTOPE; LIPID;

EID: 84944579672     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-14-0610     Document Type: Article
Times cited : (21)

References (41)
  • 2
    • 0032854224 scopus 로고    scopus 로고
    • Arterial KIC as marker of liver and muscle intracellular leucine pools in healthy and type 1 diabetic humans
    • Barazzoni R, Meek SE, Ekberg K, Wahren J & Nair KS 1999 Arterial KIC as marker of liver and muscle intracellular leucine pools in healthy and type 1 diabetic humans. American Journal of Physiology 277 E238-E244.
    • (1999) American Journal of Physiology , vol.277 , pp. E238-E244
    • Barazzoni, R.1    Meek, S.E.2    Ekberg, K.3    Wahren, J.4    Nair, K.S.5
  • 4
    • 0000246182 scopus 로고    scopus 로고
    • Free fatty acids (FFA), a link between obesity and insulin resistance
    • Boden G 1998 Free fatty acids (FFA), a link between obesity and insulin resistance. Frontiers in Bioscience 3 169-175.
    • (1998) Frontiers in Bioscience , vol.3 , pp. 169-175
    • Boden, G.1
  • 6
    • 0025264443 scopus 로고
    • Measurement of very low density and low density lipoprotein apolipoprotein (Apo) B- 100 and high density lipoprotein Apo A-I production in human subjects using deuterated leucine. Effect of fasting and feeding
    • Cohn JS, Wagner DA, Cohn SD, Millar JS & Schaefer EJ 1990 Measurement of very low density and low density lipoprotein apolipoprotein (Apo) B- 100 and high density lipoprotein Apo A-I production in human subjects using deuterated leucine. Effect of fasting and feeding. Journal of Clinical Investigation 85 804-811. (doi:10.1172/JCI114507)
    • (1990) Journal of Clinical Investigation , vol.85 , pp. 804-811
    • Cohn, J.S.1    Wagner, D.A.2    Cohn, S.D.3    Millar, J.S.4    Schaefer, E.J.5
  • 7
    • 0028819191 scopus 로고
    • Increased hepatic secretion of very-low-density-lipoprotein apolipoprotein B-100 in heterozygous familial hypercholesterolaemia: a stable isotope study
    • Cummings MH, Watts GF, UmplebyM, Hennessy TR, Quiney JR & Sönksen PH 1995 Increased hepatic secretion of very-low-density-lipoprotein apolipoprotein B-100 in heterozygous familial hypercholesterolaemia: a stable isotope study. Atherosclerosis 113 79-89. (doi:10.1016/0021- 9150(94)05430-Q)
    • (1995) Atherosclerosis , vol.113 , pp. 79-89
    • Cummings, M.H.1    Watts, G.F.2    Umpleby, M.3    Hennessy, T.R.4    Quiney, J.R.5    Sönksen, P.H.6
  • 9
    • 0033796419 scopus 로고    scopus 로고
    • Comparison of deuterium incorporation and mass isotopomer distribution analysis for measurement of human cholesterol biosynthesis
    • Di Buono M, Jones PJ, Beaumier L & Wykes LJ 2000 Comparison of deuterium incorporation and mass isotopomer distribution analysis for measurement of human cholesterol biosynthesis. Journal of Lipid Research 41 1516-1523.
    • (2000) Journal of Lipid Research , vol.41 , pp. 1516-1523
    • Di Buono, M.1    Jones, P.J.2    Beaumier, L.3    Wykes, L.J.4
  • 10
    • 0029888309 scopus 로고    scopus 로고
    • In vivo measurement of plasma cholesterol and fatty acid synthesis with deuterated water: determination of the average number of deuterium atoms incorporated
    • Diraison F, Pachiaudi C & Beylot M 1996 In vivo measurement of plasma cholesterol and fatty acid synthesis with deuterated water: determination of the average number of deuterium atoms incorporated. Metabolism 45 817-821. (doi:10.1016/S0026-0495(96)90152-3)
    • (1996) Metabolism , vol.45 , pp. 817-821
    • Diraison, F.1    Pachiaudi, C.2    Beylot, M.3
  • 11
    • 0020525233 scopus 로고
    • Treatment of hyperlipidaemia retards progression of symptomatic femoral atherosclerosis. A randomised controlled trial
    • Duffield RG, Lewis B, Miller NE, Jamieson CW, Brunt JN & Colchester AC 1983 Treatment of hyperlipidaemia retards progression of symptomatic femoral atherosclerosis. A randomised controlled trial. Lancet 2 639-642. (doi:10.1016/S0140-6736(83)92527-8)
    • (1983) Lancet , vol.2 , pp. 639-642
    • Duffield, R.G.1    Lewis, B.2    Miller, N.E.3    Jamieson, C.W.4    Brunt, J.N.5    Colchester, A.C.6
  • 12
  • 13
    • 0032986807 scopus 로고    scopus 로고
    • Effects of an oral and intravenous fat load on adipose tissue and forearm lipid metabolism
    • Evans K, Clark ML & Frayn KN 1999 Effects of an oral and intravenous fat load on adipose tissue and forearm lipid metabolism. American Journal of Physiology 276 E241-E248.
    • (1999) American Journal of Physiology , vol.276 , pp. E241-E248
    • Evans, K.1    Clark, M.L.2    Frayn, K.N.3
  • 14
    • 0033038503 scopus 로고    scopus 로고
    • Mass isotopomer distribution analysis at eight years: theoretical, analytic, and experimental considerations
    • Hellerstein MK & Neese RA 1999 Mass isotopomer distribution analysis at eight years: theoretical, analytic, and experimental considerations. American Journal of Physiology 276 E1146-E1170.
    • (1999) American Journal of Physiology , vol.276 , pp. E1146-E1170
    • Hellerstein, M.K.1    Neese, R.A.2
  • 15
    • 0020533259 scopus 로고
    • Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study
    • Hubert HB, Feinleib M, McNamara PM & Castelli WP 1983 Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study. Circulation 67 968-977. (doi:10.1161/01.CIR.67.5.968)
    • (1983) Circulation , vol.67 , pp. 968-977
    • Hubert, H.B.1    Feinleib, M.2    McNamara, P.M.3    Castelli, W.P.4
  • 16
    • 0023892689 scopus 로고
    • Plasma cholesterol synthesis using deuterated water in humans: effect of short-term food restrictions
    • Jones PJ, Scanu AM & Schoeller DA 1988 Plasma cholesterol synthesis using deuterated water in humans: effect of short-term food restrictions. Journal of Laboratory and Clinical Medicine 111 627-633.
    • (1988) Journal of Laboratory and Clinical Medicine , vol.111 , pp. 627-633
    • Jones, P.J.1    Scanu, A.M.2    Schoeller, D.A.3
  • 17
    • 0027448162 scopus 로고
    • Measurement of human lipogenesis using deuterium incorporation
    • Leitch CA & Jones PJ 1993 Measurement of human lipogenesis using deuterium incorporation. Journal of Lipid Research 34 157-163.
    • (1993) Journal of Lipid Research , vol.34 , pp. 157-163
    • Leitch, C.A.1    Jones, P.J.2
  • 19
    • 0027161715 scopus 로고
    • Evaluation of deuterated cholesterol and deuterated sitostanol formeasurement of cholesterol absorption inhumans
    • Lutjohann D, Meese CO, Crouse JR III & von Bergmann K 1993 Evaluation of deuterated cholesterol and deuterated sitostanol formeasurement of cholesterol absorption inhumans. Journal of LipidResearch 341039-1046.
    • (1993) Journal of LipidResearch , vol.34 , pp. 1039-1046
    • Lutjohann, D.1    Meese, C.O.2    Crouse J.R, I.I.I.3    von Bergmann, K.4
  • 20
  • 21
    • 1442276967 scopus 로고    scopus 로고
    • Systemic and forearm triglyceride metabolism: fate of lipoprotein lipase-generated glycerol and free fatty acids
    • Miles JM, Park YS, Walewicz D, Russell-Lopez C, Windsor S, Isley WL, Coppack SW & Harris WS 2004 Systemic and forearm triglyceride metabolism: fate of lipoprotein lipase-generated glycerol and free fatty acids. Diabetes 53 521-527. (doi:10.2337/diabetes.53.3.521)
    • (2004) Diabetes , vol.53 , pp. 521-527
    • Miles, J.M.1    Park, Y.S.2    Walewicz, D.3    Russell-Lopez, C.4    Windsor, S.5    Isley, W.L.6    Coppack, S.W.7    Harris, W.S.8
  • 23
    • 0038692192 scopus 로고    scopus 로고
    • What does the measurement of whole-body fatty acid rate of appearance in plasma by using a fatty acid tracer really mean?
    • Mittendorfer B, Liem O, Patterson BW, Miles JM & Klein S 2003 What does the measurement of whole-body fatty acid rate of appearance in plasma by using a fatty acid tracer really mean? Diabetes 52 1641-1648. (doi:10.2337/diabetes.52.7.1641)
    • (2003) Diabetes , vol.52 , pp. 1641-1648
    • Mittendorfer, B.1    Liem, O.2    Patterson, B.W.3    Miles, J.M.4    Klein, S.5
  • 26
    • 0025739878 scopus 로고
    • Determination of kinetic parameters of apolipoprotein B metabolism using amino acids labeled with stable isotopes
    • Parhofer KG, Hugh P, Barrett R, Bier DM & Schonfeld G 1991 Determination of kinetic parameters of apolipoprotein B metabolism using amino acids labeled with stable isotopes. Journal of Lipid Research 32 1311-1323.
    • (1991) Journal of Lipid Research , vol.32 , pp. 1311-1323
    • Parhofer, K.G.1    Hugh, P.2    Barrett, R.3    Bier, D.M.4    Schonfeld, G.5
  • 27
  • 28
    • 0014108686 scopus 로고
    • Glycerol kinase activities in rat heart and adipose tissue
    • Robinson J & Newsholme EA 1967 Glycerol kinase activities in rat heart and adipose tissue. Biochemical Journal 104 2c-4c.
    • (1967) Biochemical Journal , vol.104 , pp. 2c-4c
    • Robinson, J.1    Newsholme, E.A.2
  • 30
  • 31
    • 78650866632 scopus 로고
    • The investigation of intermediary metabolism with the aid of heavy hydrogen
    • Schoenheimer R 1937 The investigation of intermediary metabolism with the aid of heavy hydrogen. Bulletin of the New York Academy of Medicine 13 272-295.
    • (1937) Bulletin of the New York Academy of Medicine , vol.13 , pp. 272-295
    • Schoenheimer, R.1
  • 33
    • 77954457487 scopus 로고    scopus 로고
    • Headspace analyses of acetone: a rapid method for measuring the 2H-labeling of water
    • Shah V, Herath K, Previs SF, Hubbard BK & Roddy TP 2010 Headspace analyses of acetone: a rapid method for measuring the 2H-labeling of water. Analytical Biochemistry 404 235-237. (doi:10.1016/j.ab.2010.05.010)
    • (2010) Analytical Biochemistry , vol.404 , pp. 235-237
    • Shah, V.1    Herath, K.2    Previs, S.F.3    Hubbard, B.K.4    Roddy, T.P.5
  • 35
    • 84891770841 scopus 로고    scopus 로고
    • Prandial hypertriglyceridemia in metabolic syndrome is due to an overproduction of both chylomicron and VLDL triacylglycerol
    • Shojaee-Moradie F, Ma Y, Lou S, Hovorka R & Umpleby AM 2013 Prandial hypertriglyceridemia in metabolic syndrome is due to an overproduction of both chylomicron and VLDL triacylglycerol. Diabetes 62 4063-4069. (doi:10.2337/db13-0935)
    • (2013) Diabetes , vol.62 , pp. 4063-4069
    • Shojaee-Moradie, F.1    Ma, Y.2    Lou, S.3    Hovorka, R.4    Umpleby, A.M.5
  • 38
    • 0001147544 scopus 로고
    • Radioactive and stable isotope tracers in biomedicine
    • New York, NY, USA: Wiley Liss Inc
    • Wolfe RR 1992 Radioactive and stable isotope tracers in biomedicine. In Principles and Practice of Kinetic Analysis. New York, NY, USA: Wiley Liss Inc.
    • (1992) Principles and Practice of Kinetic Analysis
    • Wolfe, R.R.1
  • 40
    • 0022000950 scopus 로고
    • Effects of sepsis on VLDL kinetics: responses in basal state and during glucose infusion
    • Wolfe RR, Shaw JH & Durkot MJ 1985 Effects of sepsis on VLDL kinetics: responses in basal state and during glucose infusion. American Journal of Physiology 248 E732-E740.
    • (1985) American Journal of Physiology , vol.248 , pp. E732-E740
    • Wolfe, R.R.1    Shaw, J.H.2    Durkot, M.J.3
  • 41
    • 0016275140 scopus 로고
    • Validation of a dual-isotope plasma ratio method for measurement of cholesterol absorption in rats
    • Zilversmit DB & Hughes LB 1974 Validation of a dual-isotope plasma ratio method for measurement of cholesterol absorption in rats. Journal of Lipid Research 15 465-473.
    • (1974) Journal of Lipid Research , vol.15 , pp. 465-473
    • Zilversmit, D.B.1    Hughes, L.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.