Involvement of p53 in insulin-like growth factor binding protein-3 regulation in the breast cancer cell response to DNA damage

Oncotarget

Volumn 6, Issue 29, 2015, Pages 26583-26598

  Marzec, Kamila A ^a   Lin, Mike Z ^a   Martin, Janet L ^a   Baxter, Robert C ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Breast cancer; Chemotherapy; DNA damage; Insulin like growth factor binding protein 3 (IGFBP 3); P53

Indexed keywords

ANTINEOPLASTIC AGENT; DOXORUBICIN; ETOPOSIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PRIMA 1; PROTEIN P21; PROTEIN P53; SMALL INTERFERING RNA; SOMATOMEDIN BINDING PROTEIN 3; UNCLASSIFIED DRUG; CASP3 PROTEIN, HUMAN; CASPASE 3; IGFBP3 PROTEIN, HUMAN; MEMBRANE PROTEIN; NERVE PROTEIN; PRIMA1 PROTEIN, HUMAN; TP53 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BREAST CANCER CELL LINE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; DRUG MECHANISM; GAIN OF FUNCTION MUTATION; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE REPRESSION; GENE SILENCING; HS578T CELL LINE; HUMAN; HUMAN CELL; IGFBP 3 GENE; IN VITRO STUDY; MCF 10A CELL LINE; MCF 7 CELL LINE; MDA MB 231 CELL LINE; MDA MB 436 CELL LINE; MDA MB 468 CELL LINE; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RNA INTERFERENCE; T47D CELL LINE; TUMOR SUPPRESSOR GENE; UPREGULATION; BREAST TUMOR; CHEMISTRY; FEMALE; GENETICS; METABOLISM; MUTATION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CASPASE 3; CELL LINE, TUMOR; DNA DAMAGE; DOXORUBICIN; ETOPOSIDE; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; MEMBRANE PROTEINS; MUTATION; NERVE TISSUE PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84944474414     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5612     Document Type: Article

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