-
1
-
-
84861708138
-
Molecular biology in breast cancer: intrinsic subtypes and signaling pathways
-
Eroles P, Bosch A, Perez-Fidalgo JA, Lluch A. Molecular biology in breast cancer: intrinsic subtypes and signaling pathways. Cancer Treat Rev. 2012; 38:698-707.
-
(2012)
Cancer Treat Rev.
, vol.38
, pp. 698-707
-
-
Eroles, P.1
Bosch, A.2
Perez-Fidalgo, J.A.3
Lluch, A.4
-
2
-
-
84891622107
-
Biological subtypes of breast cancer: current concepts and implications for recurrence patterns
-
Cadoo KA, Fornier MN, Morris PG. Biological subtypes of breast cancer: current concepts and implications for recurrence patterns. Q J Nucl Med Mol Imaging. 2013; 57:312-321.
-
(2013)
Q J Nucl Med Mol Imaging.
, vol.57
, pp. 312-321
-
-
Cadoo, K.A.1
Fornier, M.N.2
Morris, P.G.3
-
4
-
-
78449294111
-
EGFR signaling in breast cancer: bad to the bone
-
Foley J, Nickerson NK, Nam S, Allen KT, Gilmore JL, Nephew KP, Riese DJ. EGFR signaling in breast cancer: bad to the bone. Semin Cell Dev Biol. 2010; 21:951-960.
-
(2010)
Semin Cell Dev Biol.
, vol.21
, pp. 951-960
-
-
Foley, J.1
Nickerson, N.K.2
Nam, S.3
Allen, K.T.4
Gilmore, J.L.5
Nephew, K.P.6
Riese, D.J.7
-
5
-
-
84862312210
-
Luminal breast cancer metastasis is dependent on estrogen signaling
-
Ganapathy V, Banach-Petrosky W, Xie W, Kareddula A, Nienhuis H, Miles G, Reiss M. Luminal breast cancer metastasis is dependent on estrogen signaling. Clin Exp Metastasis. 2012; 29:493-509.
-
(2012)
Clin Exp Metastasis.
, vol.29
, pp. 493-509
-
-
Ganapathy, V.1
Banach-Petrosky, W.2
Xie, W.3
Kareddula, A.4
Nienhuis, H.5
Miles, G.6
Reiss, M.7
-
6
-
-
84874857331
-
HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: implications for efficacy of adjuvant trastuzumab
-
Ithimakin S, Day KC, Malik F, Zen Q, Dawsey SJ, Bersano-Begey TF, Quraishi AA, Ignatoski KW, Daignault S, Davis A, Hall CL, Palanisamy N, Heath AN, et al. HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: implications for efficacy of adjuvant trastuzumab. Cancer Res. 2013; 73:1635-1646.
-
(2013)
Cancer Res.
, vol.73
, pp. 1635-1646
-
-
Ithimakin, S.1
Day, K.C.2
Malik, F.3
Zen, Q.4
Dawsey, S.J.5
Bersano-Begey, T.F.6
Quraishi, A.A.7
Ignatoski, K.W.8
Daignault, S.9
Davis, A.10
Hall, C.L.11
Palanisamy, N.12
Heath, A.N.13
-
7
-
-
84874204251
-
RUNX2 in mammary gland development and breast cancer
-
Ferrari N, McDonald L, Morris JS, Cameron ER, Blyth K. RUNX2 in mammary gland development and breast cancer. J Cell Physiol. 2013; 228:1137-1142.
-
(2013)
J Cell Physiol.
, vol.228
, pp. 1137-1142
-
-
Ferrari, N.1
McDonald, L.2
Morris, J.S.3
Cameron, E.R.4
Blyth, K.5
-
8
-
-
84900432506
-
RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland
-
McDonald L, Ferrari N, Terry A, Bell M, Mohammed ZM, Orange C, Jenkins A, Muller WJ, Gusterson BA, Neil JC, Edwards J, Morris JS, Cameron ER, et al. RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland. Dis Model Mech. 2014; 7:525-534.
-
(2014)
Dis Model Mech.
, vol.7
, pp. 525-534
-
-
McDonald, L.1
Ferrari, N.2
Terry, A.3
Bell, M.4
Mohammed, Z.M.5
Orange, C.6
Jenkins, A.7
Muller, W.J.8
Gusterson, B.A.9
Neil, J.C.10
Edwards, J.11
Morris, J.S.12
Cameron, E.R.13
-
9
-
-
3042825286
-
Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease
-
Barnes GL, Hebert KE, Kamal M, Javed A, Einhorn TA, Lian JB, Stein GS, Gerstenfeld LC. Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease. Cancer Res. 2004; 64:4506-4513.
-
(2004)
Cancer Res.
, vol.64
, pp. 4506-4513
-
-
Barnes, G.L.1
Hebert, K.E.2
Kamal, M.3
Javed, A.4
Einhorn, T.A.5
Lian, J.B.6
Stein, G.S.7
Gerstenfeld, L.C.8
-
10
-
-
25444473106
-
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion
-
Pratap J, Javed A, Languino LR, van Wijnen AJ, Stein JL, Stein GS, Lian JB. The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Mol Cell Biol. 2005; 25:8581-8591.
-
(2005)
Mol Cell Biol.
, vol.25
, pp. 8581-8591
-
-
Pratap, J.1
Javed, A.2
Languino, L.R.3
van Wijnen, A.J.4
Stein, J.L.5
Stein, G.S.6
Lian, J.B.7
-
11
-
-
33846034921
-
Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone
-
Pratap J, Lian JB, Javed A, Barnes GL, van Wijnen AJ, Stein JL, Stein GS. Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone. Cancer Metastasis Rev. 2006; 25:589-600.
-
(2006)
Cancer Metastasis Rev.
, vol.25
, pp. 589-600
-
-
Pratap, J.1
Lian, J.B.2
Javed, A.3
Barnes, G.L.4
van Wijnen, A.J.5
Stein, J.L.6
Stein, G.S.7
-
12
-
-
0037441529
-
Regulation of the osteoblast-specific transcription factor, Runx2: Responsiveness to multiple signal transduction pathways
-
Franceschi RT, Xiao G. Regulation of the osteoblast-specific transcription factor, Runx2: Responsiveness to multiple signal transduction pathways. J Cell Biochem. 2003; 88:446-454.
-
(2003)
J Cell Biochem.
, vol.88
, pp. 446-454
-
-
Franceschi, R.T.1
Xiao, G.2
-
13
-
-
84857320794
-
Interactions between extracellular signalregulated kinase 1/2 and p38 MAP kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity
-
Ge C, Yang Q, Zhao G, Yu H, Kirkwood KL, Franceschi RT. Interactions between extracellular signalregulated kinase 1/2 and p38 MAP kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity. J Bone Miner Res. 2012; 27:538-551.
-
(2012)
J Bone Miner Res.
, vol.27
, pp. 538-551
-
-
Ge, C.1
Yang, Q.2
Zhao, G.3
Yu, H.4
Kirkwood, K.L.5
Franceschi, R.T.6
-
14
-
-
20144365699
-
Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription
-
Afzal F, Pratap J, Ito K, Ito Y, Stein JL, van Wijnen AJ, Stein GS, Lian JB, Javed A. Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription. J Cell Physiol. 2005; 204:63-72.
-
(2005)
J Cell Physiol.
, vol.204
, pp. 63-72
-
-
Afzal, F.1
Pratap, J.2
Ito, K.3
Ito, Y.4
Stein, J.L.5
van Wijnen, A.J.6
Stein, G.S.7
Lian, J.B.8
Javed, A.9
-
15
-
-
0034460993
-
Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12
-
Lee KS, Kim HJ, Li QL, Chi XZ, Ueta C, Komori T, Wozney JM, Kim EG, Choi JY, Ryoo HM, Bae SC. Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12. Mol Cell Biol. 2000; 20:8783-8792.
-
(2000)
Mol Cell Biol.
, vol.20
, pp. 8783-8792
-
-
Lee, K.S.1
Kim, H.J.2
Li, Q.L.3
Chi, X.Z.4
Ueta, C.5
Komori, T.6
Wozney, J.M.7
Kim, E.G.8
Choi, J.Y.9
Ryoo, H.M.10
Bae, S.C.11
-
16
-
-
2942574380
-
Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins
-
Miyazono K, Maeda S, Imamura T. Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins. Oncogene. 2004; 23:4232-4237.
-
(2004)
Oncogene.
, vol.23
, pp. 4232-4237
-
-
Miyazono, K.1
Maeda, S.2
Imamura, T.3
-
17
-
-
3042549099
-
Smad3 interacts with JunB and Cbfa1/Runx2 for transforming growth factor-beta1-stimulated collagenase-3 expression in human breast cancer cells
-
Selvamurugan N, Kwok S, Partridge NC. Smad3 interacts with JunB and Cbfa1/Runx2 for transforming growth factor-beta1-stimulated collagenase-3 expression in human breast cancer cells. J Biol Chem. 2004; 279:27764-27773.
-
(2004)
J Biol Chem.
, vol.279
, pp. 27764-27773
-
-
Selvamurugan, N.1
Kwok, S.2
Partridge, N.C.3
-
18
-
-
68749118305
-
Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer
-
Das K, Leong DT, Gupta A, Shen L, Putti T, Stein GS, van Wijnen AJ, Salto-Tellez M. Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer. Eur J Cancer. 2009; 45:2239-2248.
-
(2009)
Eur J Cancer.
, vol.45
, pp. 2239-2248
-
-
Das, K.1
Leong, D.T.2
Gupta, A.3
Shen, L.4
Putti, T.5
Stein, G.S.6
van Wijnen, A.J.7
Salto-Tellez, M.8
-
19
-
-
78449307996
-
Runx2 in human breast carcinoma: its potential roles in cancer progression
-
Onodera Y, Miki Y, Suzuki T, Takagi K, Akahira J, Sakyu T, Watanabe M, Inoue S, Ishida T, Ohuchi N, Sasano H. Runx2 in human breast carcinoma: its potential roles in cancer progression. Cancer Sci. 2010; 101:2670-2675.
-
(2010)
Cancer Sci.
, vol.101
, pp. 2670-2675
-
-
Onodera, Y.1
Miki, Y.2
Suzuki, T.3
Takagi, K.4
Akahira, J.5
Sakyu, T.6
Watanabe, M.7
Inoue, S.8
Ishida, T.9
Ohuchi, N.10
Sasano, H.11
-
20
-
-
84859949726
-
Tumor initiating but differentiated luminallike breast cancer cells are highly invasive in the absence of basal-like activity
-
Kim J, Villadsen R, Sorlie T, Fogh L, Gronlund SZ, Fridriksdottir AJ, Kuhn I, Rank F, Wielenga VT, Solvang H, Edwards PA, Borresen-Dale AL, Ronnov-Jessen , et al. Tumor initiating but differentiated luminallike breast cancer cells are highly invasive in the absence of basal-like activity. Proc Natl Acad Sci U S A. 2012; 109:6124-6129.
-
(2012)
Proc Natl Acad Sci U S A.
, vol.109
, pp. 6124-6129
-
-
Kim, J.1
Villadsen, R.2
Sorlie, T.3
Fogh, L.4
Gronlund, S.Z.5
Fridriksdottir, A.J.6
Kuhn, I.7
Rank, F.8
Wielenga, V.T.9
Solvang, H.10
Edwards, P.A.11
Borresen-Dale, A.L.12
Ronnov-Jessen, .13
-
21
-
-
0033522472
-
A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator
-
Yagi R, Chen LF, Shigesada K, Murakami Y, Ito Y. A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. Embo J. 1999; 18:2551-2562.
-
(1999)
Embo J.
, vol.18
, pp. 2551-2562
-
-
Yagi, R.1
Chen, L.F.2
Shigesada, K.3
Murakami, Y.4
Ito, Y.5
-
22
-
-
0037306788
-
Transcriptional coactivation of bone-specific transcription factor Cbfa1 by TAZ
-
Cui CB, Cooper LF, Yang X, Karsenty G, Aukhil I. Transcriptional coactivation of bone-specific transcription factor Cbfa1 by TAZ. Mol Cell Biol. 2003; 23:1004-1013.
-
(2003)
Mol Cell Biol.
, vol.23
, pp. 1004-1013
-
-
Cui, C.B.1
Cooper, L.F.2
Yang, X.3
Karsenty, G.4
Aukhil, I.5
-
23
-
-
42449103970
-
The RUNX2 Transcription Factor Cooperates with the YES-associated Protein, YAP65, to Promote Cell Transformation
-
Vitolo MI, Anglin IE, Mahoney WM Jr, Renoud KJ, Gartenhaus RB, Bachman KE, Passaniti A. The RUNX2 Transcription Factor Cooperates with the YES-associated Protein, YAP65, to Promote Cell Transformation. Cancer Biol Ther. 2007; 6:856-863.
-
(2007)
Cancer Biol Ther.
, vol.6
, pp. 856-863
-
-
Vitolo, M.I.1
Anglin, I.E.2
Mahoney, W.M.3
Renoud, K.J.4
Gartenhaus, R.B.5
Bachman, K.E.6
Passaniti, A.7
-
24
-
-
46049087598
-
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
-
Varelas X, Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J, Yaffe MB, Zandstra PW, Wrana JL. TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. Nat Cell Biol. 2008; 10:837-848.
-
(2008)
Nat Cell Biol.
, vol.10
, pp. 837-848
-
-
Varelas, X.1
Sakuma, R.2
Samavarchi-Tehrani, P.3
Peerani, R.4
Rao, B.M.5
Dembowy, J.6
Yaffe, M.B.7
Zandstra, P.W.8
Wrana, J.L.9
-
25
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR, Poletti A, Daidone MG, Dupont S, Basso G, et al. The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell. 2011; 147:759-772.
-
(2011)
Cell.
, vol.147
, pp. 759-772
-
-
Cordenonsi, M.1
Zanconato, F.2
Azzolin, L.3
Forcato, M.4
Rosato, A.5
Frasson, C.6
Inui, M.7
Montagner, M.8
Parenti, A.R.9
Poletti, A.10
Daidone, M.G.11
Dupont, S.12
Basso, G.13
-
26
-
-
84900424727
-
The transcriptional regulators TAZ and YAP direct transforming growth factor beta-induced tumorigenic phenotypes in breast cancer cells
-
Hiemer SE, Szymaniak AD, Varelas X. The transcriptional regulators TAZ and YAP direct transforming growth factor beta-induced tumorigenic phenotypes in breast cancer cells. J Biol Chem. 2014; 289:13461-13474.
-
(2014)
J Biol Chem.
, vol.289
, pp. 13461-13474
-
-
Hiemer, S.E.1
Szymaniak, A.D.2
Varelas, X.3
-
27
-
-
84862951862
-
Regulation and function of the TAZ transcription co-activator
-
Liu C, Huang W, Lei Q. Regulation and function of the TAZ transcription co-activator. Int J Biochem Mol Biol. 2011; 2:247-256.
-
(2011)
Int J Biochem Mol Biol.
, vol.2
, pp. 247-256
-
-
Liu, C.1
Huang, W.2
Lei, Q.3
-
28
-
-
42349088170
-
A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells
-
Chan SW, Lim CJ, Guo K, Ng CP, Lee I, Hunziker W, Zeng Q, Hong W. A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. Cancer Res. 2008; 68:2592-2598.
-
(2008)
Cancer Res.
, vol.68
, pp. 2592-2598
-
-
Chan, S.W.1
Lim, C.J.2
Guo, K.3
Ng, C.P.4
Lee, I.5
Hunziker, W.6
Zeng, Q.7
Hong, W.8
-
29
-
-
41149098966
-
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
-
Lei QY, Zhang H, Zhao B, Zha ZY, Bai F, Pei XH, Zhao S, Xiong Y, Guan KL. TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Mol Cell Biol. 2008; 28:2426-2436.
-
(2008)
Mol Cell Biol.
, vol.28
, pp. 2426-2436
-
-
Lei, Q.Y.1
Zhang, H.2
Zhao, B.3
Zha, Z.Y.4
Bai, F.5
Pei, X.H.6
Zhao, S.7
Xiong, Y.8
Guan, K.L.9
-
30
-
-
84871425210
-
Bone metastatic process of breast cancer involves methylation state affecting E-cadherin expression through TAZ and WWOX nuclear effectors
-
Matteucci E, Maroni P, Luzzati A, Perrucchini G, Bendinelli P, Desiderio MA. Bone metastatic process of breast cancer involves methylation state affecting E-cadherin expression through TAZ and WWOX nuclear effectors. Eur J Cancer. 2013; 49:231-244.
-
(2013)
Eur J Cancer.
, vol.49
, pp. 231-244
-
-
Matteucci, E.1
Maroni, P.2
Luzzati, A.3
Perrucchini, G.4
Bendinelli, P.5
Desiderio, M.A.6
-
31
-
-
33645302628
-
The epithelialmesenchymal transition: new insights in signaling, development, and disease
-
Lee JM, Dedhar S, Kalluri R, Thompson EW. The epithelialmesenchymal transition: new insights in signaling, development, and disease. J Cell Biol. 2006; 172:973-981.
-
(2006)
J Cell Biol.
, vol.172
, pp. 973-981
-
-
Lee, J.M.1
Dedhar, S.2
Kalluri, R.3
Thompson, E.W.4
-
32
-
-
70450198396
-
Epithelialmesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelialmesenchymal transitions in development and disease. Cell. 2009; 139:871-890.
-
(2009)
Cell.
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
33
-
-
80054686286
-
Tumor metastasis: molecular insights and evolving paradigms
-
Valastyan S, Weinberg RA. Tumor metastasis: molecular insights and evolving paradigms. Cell. 2011; 147:275-292.
-
(2011)
Cell.
, vol.147
, pp. 275-292
-
-
Valastyan, S.1
Weinberg, R.A.2
-
34
-
-
84874647804
-
Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer
-
Hollestelle A, Peeters JK, Smid M, Timmermans M, Verhoog LC, Westenend PJ, Heine AA, Chan A, Sieuwerts AM, Wiemer EA, Klijn JG, van der Spek PJ, Foekens JA, et al. Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer. Breast Cancer Res Treat. 2013; 138:47-57.
-
(2013)
Breast Cancer Res Treat.
, vol.138
, pp. 47-57
-
-
Hollestelle, A.1
Peeters, J.K.2
Smid, M.3
Timmermans, M.4
Verhoog, L.C.5
Westenend, P.J.6
Heine, A.A.7
Chan, A.8
Sieuwerts, A.M.9
Wiemer, E.A.10
Klijn, J.G.11
van der Spek, P.J.12
Foekens, J.A.13
-
35
-
-
84862535544
-
Dishonorable discharge: the oncogenic roles of cleaved E-cadherin fragments
-
David JM, Rajasekaran AK. Dishonorable discharge: the oncogenic roles of cleaved E-cadherin fragments. Cancer Res. 2012; 72:2917-2923.
-
(2012)
Cancer Res.
, vol.72
, pp. 2917-2923
-
-
David, J.M.1
Rajasekaran, A.K.2
-
36
-
-
84859237507
-
Soluble E-cadherin: more than a symptom of disease
-
Grabowska MM, Day ML. Soluble E-cadherin: more than a symptom of disease. Front Biosci (Landmark Ed). 2012; 17:1948-1964.
-
(2012)
Front Biosci (Landmark Ed).
, vol.17
, pp. 1948-1964
-
-
Grabowska, M.M.1
Day, M.L.2
-
37
-
-
8444230329
-
Dual roles of E-cadherin in prostate cancer invasion
-
Chunthapong J, Seftor EA, Khalkhali-Ellis Z, Seftor RE, Amir S, Lubaroff DM, Heidger PM Jr, Hendrix MJ. Dual roles of E-cadherin in prostate cancer invasion. J Cell Biochem. 2004; 91:649-661.
-
(2004)
J Cell Biochem.
, vol.91
, pp. 649-661
-
-
Chunthapong, J.1
Seftor, E.A.2
Khalkhali-Ellis, Z.3
Seftor, R.E.4
Amir, S.5
Lubaroff, D.M.6
Heidger, P.M.7
Hendrix, M.J.8
-
38
-
-
79952192747
-
Soluble E-cadherin promotes cell survival by activating epidermal growth factor receptor
-
Inge LJ, Barwe SP, D'Ambrosio J, Gopal J, Lu K, Ryazantsev S, Rajasekaran SA, Rajasekaran AK. Soluble E-cadherin promotes cell survival by activating epidermal growth factor receptor. Exp Cell Res. 2011; 317:838-848.
-
(2011)
Exp Cell Res.
, vol.317
, pp. 838-848
-
-
Inge, L.J.1
Barwe, S.P.2
D'Ambrosio, J.3
Gopal, J.4
Lu, K.5
Ryazantsev, S.6
Rajasekaran, S.A.7
Rajasekaran, A.K.8
-
39
-
-
0346963104
-
The role of an 80 kDa fragment of E-cadherin in the metastatic progression of prostate cancer
-
Kuefer R, Hofer MD, Gschwend JE, Pienta KJ, Sanda MG, Chinnaiyan AM, Rubin MA, Day ML. The role of an 80 kDa fragment of E-cadherin in the metastatic progression of prostate cancer. Clin Cancer Res. 2003; 9:6447-6452.
-
(2003)
Clin Cancer Res.
, vol.9
, pp. 6447-6452
-
-
Kuefer, R.1
Hofer, M.D.2
Gschwend, J.E.3
Pienta, K.J.4
Sanda, M.G.5
Chinnaiyan, A.M.6
Rubin, M.A.7
Day, M.L.8
-
40
-
-
49649103585
-
The ectodomain shedding of E-cadherin by ADAM15 supports ErbB receptor activation
-
Najy AJ, Day KC, Day ML. The ectodomain shedding of E-cadherin by ADAM15 supports ErbB receptor activation. J Biol Chem. 2008; 283:18393-18401.
-
(2008)
J Biol Chem.
, vol.283
, pp. 18393-18401
-
-
Najy, A.J.1
Day, K.C.2
Day, M.L.3
-
41
-
-
0034787354
-
Matrilysin mediates extracellular cleavage of E-cadherin from prostate cancer cells: a key mechanism in hepatocyte growth factor/scatter factor-induced cell-cell dissociation and in vitro invasion
-
Davies G, Jiang WG, Mason MD. Matrilysin mediates extracellular cleavage of E-cadherin from prostate cancer cells: a key mechanism in hepatocyte growth factor/scatter factor-induced cell-cell dissociation and in vitro invasion. Clin Cancer Res. 2001; 7:3289-3297.
-
(2001)
Clin Cancer Res.
, vol.7
, pp. 3289-3297
-
-
Davies, G.1
Jiang, W.G.2
Mason, M.D.3
-
42
-
-
47749097160
-
The metalloprotease meprinbeta processes E-cadherin and weakens intercellular adhesion
-
Huguenin M, Muller EJ, Trachsel-Rosmann S, Oneda B, Ambort D, Sterchi EE, Lottaz D. The metalloprotease meprinbeta processes E-cadherin and weakens intercellular adhesion. PLoS One. 2008; 3:e2153.
-
(2008)
PLoS One.
, vol.3
-
-
Huguenin, M.1
Muller, E.J.2
Trachsel-Rosmann, S.3
Oneda, B.4
Ambort, D.5
Sterchi, E.E.6
Lottaz, D.7
-
43
-
-
0035147313
-
Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1
-
Noe V, Fingleton B, Jacobs K, Crawford HC, Vermeulen S, Steelant W, Bruyneel E, Matrisian LM, Mareel M. Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1. J Cell Sci. 2001; 114:111-118.
-
(2001)
J Cell Sci.
, vol.114
, pp. 111-118
-
-
Noe, V.1
Fingleton, B.2
Jacobs, K.3
Crawford, H.C.4
Vermeulen, S.5
Steelant, W.6
Bruyneel, E.7
Matrisian, L.M.8
Mareel, M.9
-
44
-
-
33947219432
-
Engagement of collagen-binding integrins promotes matrix metalloproteinase-9-dependent E-cadherin ectodomain shedding in ovarian carcinoma cells
-
Symowicz J, Adley BP, Gleason KJ, Johnson JJ, Ghosh S, Fishman DA, Hudson LG, Stack MS. Engagement of collagen-binding integrins promotes matrix metalloproteinase-9-dependent E-cadherin ectodomain shedding in ovarian carcinoma cells. Cancer Res. 2007; 67:2030-2039.
-
(2007)
Cancer Res.
, vol.67
, pp. 2030-2039
-
-
Symowicz, J.1
Adley, B.P.2
Gleason, K.J.3
Johnson, J.J.4
Ghosh, S.5
Fishman, D.A.6
Hudson, L.G.7
Stack, M.S.8
-
45
-
-
84860389234
-
Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT-like phenotype change and MMP-9-mediated degradation of E-cadherin
-
Zuo JH, Zhu W, Li MY, Li XH, Yi H, Zeng GQ, Wan XX, He QY, Li JH, Qu JQ, Chen Y, Xiao ZQ. Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT-like phenotype change and MMP-9-mediated degradation of E-cadherin. J Cell Biochem. 2011; 112:2508-2517.
-
(2011)
J Cell Biochem.
, vol.112
, pp. 2508-2517
-
-
Zuo, J.H.1
Zhu, W.2
Li, M.Y.3
Li, X.H.4
Yi, H.5
Zeng, G.Q.6
Wan, X.X.7
He, Q.Y.8
Li, J.H.9
Qu, J.Q.10
Chen, Y.11
Xiao, Z.Q.12
-
46
-
-
84879486621
-
Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathways
-
Brouxhon SM, Kyrkanides S, Teng X, Raja V, O'Banion MK, Clarke R, Byers S, Silberfeld A, Tornos C, Ma L. Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathways. Clin Cancer Res. 2013; 19:3234-3246.
-
(2013)
Clin Cancer Res.
, vol.19
, pp. 3234-3246
-
-
Brouxhon, S.M.1
Kyrkanides, S.2
Teng, X.3
Raja, V.4
O'Banion, M.K.5
Clarke, R.6
Byers, S.7
Silberfeld, A.8
Tornos, C.9
Ma, L.10
-
47
-
-
84907951215
-
Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers
-
Brouxhon SM, Kyrkanides S, Teng X, O'Banion MK, Clarke R, Byers S, Ma L. Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers. Mol Carcinog. 2014; 53:893-906.
-
(2014)
Mol Carcinog.
, vol.53
, pp. 893-906
-
-
Brouxhon, S.M.1
Kyrkanides, S.2
Teng, X.3
O'Banion, M.K.4
Clarke, R.5
Byers, S.6
Ma, L.7
-
48
-
-
84884351343
-
The predictive value of serum soluble E-cadherin levels in breast cancer patients undergoing preoperative systemic chemotherapy
-
Hofmann G, Balic M, Dandachi N, Resel M, Schippinger W, Regitnig P, et al. The predictive value of serum soluble E-cadherin levels in breast cancer patients undergoing preoperative systemic chemotherapy. Clin Biochem. 2013; 46:1585-1589.
-
(2013)
Clin Biochem.
, vol.46
, pp. 1585-1589
-
-
Hofmann, G.1
Balic, M.2
Dandachi, N.3
Resel, M.4
Schippinger, W.5
Regitnig, P.6
-
49
-
-
21244455939
-
Assessment of a fragment of e-cadherin as a serum biomarker with predictive value for prostate cancer
-
Kuefer R, Hofer MD, Zorn CS, Engel O, Volkmer BG, Juarez-Brito MA, et al. Assessment of a fragment of e-cadherin as a serum biomarker with predictive value for prostate cancer. Br J Cancer. 2005; 92:2018-2023.
-
(2005)
Br J Cancer.
, vol.92
, pp. 2018-2023
-
-
Kuefer, R.1
Hofer, M.D.2
Zorn, C.S.3
Engel, O.4
Volkmer, B.G.5
Juarez-Brito, M.A.6
-
50
-
-
84866340501
-
Quantitative approaches to cancer stem cells and epithelial-mesenchymal transition
-
Turner C, Kohandel M. Quantitative approaches to cancer stem cells and epithelial-mesenchymal transition. Semin Cancer Biol. 2012; 22:374-378.
-
(2012)
Semin Cancer Biol.
, vol.22
, pp. 374-378
-
-
Turner, C.1
Kohandel, M.2
-
51
-
-
84939182991
-
The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells
-
[Epub ahead of print] Mar 24
-
Choe M, Brusgard JL, Chumsri S, Bhandary L, Zhao XF, Lu S, et al. The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells. J Cell Biochem. 2015; Mar 24 doi: 10.1002/jcb.25171. [Epub ahead of print].
-
(2015)
J Cell Biochem.
-
-
Choe, M.1
Brusgard, J.L.2
Chumsri, S.3
Bhandary, L.4
Zhao, X.F.5
Lu, S.6
-
52
-
-
84883628313
-
A Quantitative Assay to Study Protein:D.N.A Interactions. Discover Transcriptional Regulators of Gene Expression. Identify Novel Anti-tumor Agents
-
8/31/2013
-
Underwood KF, Mochin MT, Brusgard JL, Choe M, Gnatt A, Passaniti A. A Quantitative Assay to Study Protein:DNA Interactions, Discover Transcriptional Regulators of Gene Expression, and Identify Novel Anti-tumor Agents. J Vis Exp. 2013. 8/31/2013.
-
(2013)
J Vis Exp
-
-
Underwood, K.F.1
Mochin, M.T.2
Brusgard, J.L.3
Choe, M.4
Gnatt, A.5
Passaniti, A.6
-
53
-
-
33646350024
-
Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation
-
Qiao M, Shapiro P, Fosbrink M, Rus H, Kumar R, Passaniti A. Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation. J Biol Chem. 2006; 281:7118-7128.
-
(2006)
J Biol Chem.
, vol.281
, pp. 7118-7128
-
-
Qiao, M.1
Shapiro, P.2
Fosbrink, M.3
Rus, H.4
Kumar, R.5
Passaniti, A.6
-
54
-
-
34047117981
-
Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells
-
Rajgopal A, Young DW, Mujeeb KA, Stein JL, Lian JB, van Wijnen AJ, et al. Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells. J Cell Biochem. 2007; 100:1509-1517.
-
(2007)
J Cell Biochem.
, vol.100
, pp. 1509-1517
-
-
Rajgopal, A.1
Young, D.W.2
Mujeeb, K.A.3
Stein, J.L.4
Lian, J.B.5
van Wijnen, A.J.6
-
55
-
-
5144230325
-
Nuclear microenvironments support assembly and organization of the transcriptional regulatory machinery for cell proliferation and differentiation
-
Stein GS, Lian JB, van Wijnen AJ, Stein JL, Javed A, Montecino M, et al. Nuclear microenvironments support assembly and organization of the transcriptional regulatory machinery for cell proliferation and differentiation. J Cell Biochem. 2004; 91:287-302.
-
(2004)
J Cell Biochem.
, vol.91
, pp. 287-302
-
-
Stein, G.S.1
Lian, J.B.2
van Wijnen, A.J.3
Stein, J.L.4
Javed, A.5
Montecino, M.6
-
56
-
-
32044468546
-
Phosphorylation, acetylation and ubiquitination: the molecular basis of RUNX regulation
-
Bae SC, Lee YH. Phosphorylation, acetylation and ubiquitination: the molecular basis of RUNX regulation. Gene. 2006; 366:58-66.
-
(2006)
Gene.
, vol.366
, pp. 58-66
-
-
Bae, S.C.1
Lee, Y.H.2
-
57
-
-
83055168263
-
Regulation of breast cancer metastasis by Runx2, estrogen signaling: the role of S.N.A.I2
-
Chimge NO, Baniwal SK, Little GH, Chen YB, Kahn M, Tripathy D, et al. Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2. Breast Cancer Res. 2011; 13:R127.58
-
(2011)
Breast Cancer Res
, vol.13
-
-
Chimge, N.O.1
Baniwal, S.K.2
Little, G.H.3
Chen, Y.B.4
Kahn, M.5
Tripathy, D.6
-
58
-
-
0032572526
-
E-Cadherin-dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27(KIP1)
-
St. Croix B, Sheehan C, Rak JW, Florenes VA, Slingerland JM & Kerbel RS. E-Cadherin-dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27(KIP1). J Cell Biol. 1998; 142:557-571.
-
(1998)
J Cell Biol.
, vol.142
, pp. 557-571
-
-
St. Croix, B.1
Sheehan, C.2
Rak, J.W..3
Florenes, V.A.4
Slingerland, J.M.5
Kerbel, R.S.6
-
59
-
-
84907951215
-
Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers
-
Brouxhon SM, Kyrkanides S, Teng X, O'Banion MK, Clarke R, Byers S, Ma L. Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers. Mol Carcinog. 2014; 53:893-906.
-
(2014)
Mol Carcinog
, vol.53
, pp. 893-906
-
-
Brouxhon, S.M.1
Kyrkanides, S.2
Teng, X.3
O'Banion, M.K.4
Clarke, R.5
Byers, S.6
Ma, L.7
-
60
-
-
33646712747
-
Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer
-
Nahta R, Yu D, Hung MC, Hortobagyi GN, Esteva FJ. Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer. Nat Clin Pract Oncol. 2006; 3:269-280.
-
(2006)
Nat Clin Pract Oncol
, vol.3
, pp. 269-280
-
-
Nahta, R.1
Yu, D.2
Hung, M.C.3
Hortobagyi, G.N.4
Esteva, F.J.5
-
61
-
-
84891906452
-
Soluble E-cadherin: a critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling
-
Brouxhon SM, Kyrkanides S, Teng X, Athar M, Ghazizadeh S, Simon M, O'Banion MK, Ma L. Soluble E-cadherin: a critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling. Oncogene. 2014; 33:225-235.
-
(2014)
Oncogene
, vol.33
, pp. 225-235
-
-
Brouxhon, S.M.1
Kyrkanides, S.2
Teng, X.3
Athar, M.4
Ghazizadeh, S.5
Simon, M.6
O'Banion, M.K.7
Ma, L.8
-
62
-
-
77950814305
-
Premalignant breast neoplasia: a paradigm of interlesional and intralesional molecular heterogeneity and its biological and clinical ramifications
-
Berman HK, Gauthier ML, Tlsty TD. Premalignant breast neoplasia: a paradigm of interlesional and intralesional molecular heterogeneity and its biological and clinical ramifications. Cancer Prev Res (Phila). 2010; 3:579-587.
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 579-587
-
-
Berman, H.K.1
Gauthier, M.L.2
Tlsty, T.D.3
-
63
-
-
84856523566
-
Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness
-
Chimge NO, Baniwal SK, Luo J, Coetzee S, Khalid O, Berman BP, Tripathy D, Ellis MJ, Frenkel B. Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness. Clin Cancer Res. 2012; 18:901-911.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 901-911
-
-
Chimge, N.O.1
Baniwal, S.K.2
Luo, J.3
Coetzee, S.4
Khalid, O.5
Berman, B.P.6
Tripathy, D.7
Ellis, M.J.8
Frenkel, B.9
-
64
-
-
84876923776
-
The RUNX family in breast cancer: relationships with estrogen signaling
-
Chimge NO, Frenkel B. The RUNX family in breast cancer: relationships with estrogen signaling. Oncogene. 2013; 32:2121-2130.
-
(2013)
Oncogene.
, vol.32
, pp. 2121-2130
-
-
Chimge, N.O.1
Frenkel, B.2
-
65
-
-
84885428787
-
Targeting transcription factors: promising new strategies for cancer therapy
-
Yeh JE, Toniolo PA, Frank DA. Targeting transcription factors: promising new strategies for cancer therapy. Curr Opin Oncol. 2013; 25:652-658.
-
(2013)
Curr Opin Oncol.
, vol.25
, pp. 652-658
-
-
Yeh, J.E.1
Toniolo, P.A.2
Frank, D.A.3
-
66
-
-
84858734844
-
Regulation of RUNX2 transcription factor-DNA interactions and cell proliferation by Vitamin D3 (cholecalciferol) prohormone activity
-
Underwood KF, D'Souza DR, Mochin MT, Pierce A, Kommineni S, Choe M, Bennett J, Gnatt A, Habtemariam B, Mackerell AD Jr, Passaniti A. Regulation of RUNX2 transcription factor-DNA interactions and cell proliferation by Vitamin D3 (cholecalciferol) prohormone activity. J Bone Min Res. 2012; 27:913-925.
-
(2012)
J Bone Min Res.
, vol.27
, pp. 913-925
-
-
Underwood, K.F.1
D'Souza, D.R.2
Mochin, M.T.3
Pierce, A.4
Kommineni, S.5
Choe, M.6
Bennett, J.7
Gnatt, A.8
Habtemariam, B.9
Mackerell, A.D.10
Passaniti, A.11
-
67
-
-
0034056341
-
Cellular and molecular basis of preferential metastasis of breast cancer to bone
-
Yoneda T. Cellular and molecular basis of preferential metastasis of breast cancer to bone. J Orthop Sci. 2000; 5:75-81.
-
(2000)
J Orthop Sci.
, vol.5
, pp. 75-81
-
-
Yoneda, T.1
-
68
-
-
84920031404
-
Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets
-
Frangou C, Li YW, Shen H, Yang N, Wilson KE, Blijlevens M, Guo J, Nowak NJ, Zhang J. Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets. Oncotarget. 2014; 5:12166-12176.
-
(2014)
Oncotarget.
, vol.5
, pp. 12166-12176
-
-
Frangou, C.1
Li, Y.W.2
Shen, H.3
Yang, N.4
Wilson, K.E.5
Blijlevens, M.6
Guo, J.7
Nowak, N.J.8
Zhang, J.9
-
69
-
-
85005916226
-
deltaEF1 associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells
-
Fukagawa A, Ishii H, Miyazawa K, Saitoh M. deltaEF1 associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells. Cancer Med. 2015; 4:125-135.
-
(2015)
Cancer Med.
, vol.4
, pp. 125-135
-
-
Fukagawa, A.1
Ishii, H.2
Miyazawa, K.3
Saitoh, M.4
-
70
-
-
44449111555
-
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
-
Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, Weinberg RA. Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res. 2008; 68:3645-3654.
-
(2008)
Cancer Res
, vol.68
, pp. 3645-3654
-
-
Onder, T.T.1
Gupta, P.B.2
Mani, S.A.3
Yang, J.4
Lander, E.S.5
Weinberg, R.A.6
|