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Volumn 47, Issue 10, 2015, Pages 1206-1211

Genetic association analyses highlight biological pathways underlying mitral valve prolapsed

(39)  Dina, Christian a,b   Bouatia Naji, Nabila c,d   Tucker, Nathan e   Delling, Francesca N f,g   Toomer, Katelynn h   Durst, Ronen i   Perrocheau, Maelle c,d   Fernandez Friera, Leticia j,k   Solis, Jorge j,k   Le Tourneau, Thierry a,b   Chen, Ming Huei f,l   Probst, Vincent a,b   Bosse, Yohan m   Pibarot, Philippe m   Zelenika, Diana n   Lathrop, Mark n,o   Hercberg, Serge d,p,q,r   Roussel, Ronan d,s,t   Benjamin, Emelia J f,g   Bonnet, Fabrice u,v   more..

a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

TENSIN; TENSIN 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 84944358134     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3383     Document Type: Article
Times cited : (101)

References (38)
  • 1
    • 0037009982 scopus 로고    scopus 로고
    • Mitral valve prolapse in the general population: The benign nature of echocardiographic features in the framingham heart study
    • Freed L.A., et al. Mitral valve prolapse in the general population: the benign nature of echocardiographic features in the Framingham Heart Study. J. Am. Coll. Cardiol. 40, 1298-1304 (2002
    • (2002) J. Am. Coll. Cardiol , vol.40 , pp. 1298-1304
    • Freed, L.A.1
  • 2
    • 0033365009 scopus 로고    scopus 로고
    • Mapping of a first locus for autosomal dominant myxomatous mitral valve prolapse to chromosome 16p11.2-p12.1
    • Disse S., et al. Mapping of a first locus for autosomal dominant myxomatous mitral valve prolapse to chromosome 16p11.2-p12.1. Am. J. Hum. Genet. 65, 1242-1251 (1999
    • (1999) Am. J. Hum. Genet , vol.65 , pp. 1242-1251
    • Disse, S.1
  • 3
    • 0038353677 scopus 로고    scopus 로고
    • A locus for autosomal dominant mitral valve prolapse on chromosome 11p15.4
    • Freed L.A., et al. A locus for autosomal dominant mitral valve prolapse on chromosome 11p15.4. Am. J. Hum. Genet. 72, 1551-1559 (2003
    • (2003) Am. J. Hum. Genet , vol.72 , pp. 1551-1559
    • Freed, L.A.1
  • 4
    • 17344374187 scopus 로고    scopus 로고
    • Mapping of X-linked myxomatous valvular dystrophy to chromosome Xq28
    • Kyndt F., et al. Mapping of X-linked myxomatous valvular dystrophy to chromosome Xq28. Am. J. Hum. Genet. 62, 627-632 (1998
    • (1998) Am. J. Hum. Genet , vol.62 , pp. 627-632
    • Kyndt, F.1
  • 5
    • 25444451002 scopus 로고    scopus 로고
    • New locus for autosomal dominant mitral valve prolapse on chromosome 13: Clinical insights from genetic studies
    • Nesta F., et al. New locus for autosomal dominant mitral valve prolapse on chromosome 13: clinical insights from genetic studies. Circulation 112, 2022-2030 (2005
    • (2005) Circulation , vol.112 , pp. 2022-2030
    • Nesta, F.1
  • 6
    • 26444438115 scopus 로고    scopus 로고
    • Lmcd1/dyxin is a novel transcriptional cofactor that restricts gata6 function by inhibiting DNA binding
    • Rath N., Wang Z., Lu M.M., & Morrisey E.E. LMCD1/Dyxin is a novel transcriptional cofactor that restricts GATA6 function by inhibiting DNA binding. Mol. Cell. Biol. 25, 8864-8873 (2005
    • (2005) Mol. Cell. Biol , vol.25 , pp. 8864-8873
    • Rath, N.1    Wang, Z.2    Lu, M.M.3    Morrisey, E.E.4
  • 7
    • 0037056114 scopus 로고    scopus 로고
    • Natural history of asymptomatic mitral valve prolapse in the community
    • Avierinos J.F., et al. Natural history of asymptomatic mitral valve prolapse in the community. Circulation 106, 1355-1361 (2002
    • (2002) Circulation , vol.106 , pp. 1355-1361
    • Avierinos, J.F.1
  • 8
    • 0033168952 scopus 로고    scopus 로고
    • Prevalence and clinical outcome of mitral valve prolapse
    • Freed L.A., et al. Prevalence and clinical outcome of mitral valve prolapse. N. Engl. J. Med. 341, 1-7 (1999
    • (1999) N. Engl. J. Med , vol.341 , pp. 1-7
    • Freed, L.A.1
  • 9
    • 0020463491 scopus 로고
    • Inheritance of mitral valve prolapse: Effect of age and sex on gene expression
    • Devereux R.B., Brown W.T., Kramer-Fox R., & Sachs I. Inheritance of mitral valve prolapse: effect of age and sex on gene expression. Ann. Intern. Med. 97, 826-832 (1982
    • (1982) Ann. Intern. Med , vol.97 , pp. 826-832
    • Devereux, R.B.1    Brown, W.T.2    Kramer-Fox, R.3    Sachs, I.4
  • 10
    • 84896544588 scopus 로고    scopus 로고
    • Mild expression of mitral valve prolapse in the Framingham offspring: Expanding the phenotypic spectrum
    • Delling F.N., et al. Mild expression of mitral valve prolapse in the Framingham offspring: expanding the phenotypic spectrum. J. Am. Soc. Echocardiogr. 27, 17-23 (2014
    • (2014) J. Am. Soc. Echocardiogr , vol.27 , pp. 17-23
    • Delling, F.N.1
  • 11
    • 0024321925 scopus 로고
    • Association of mitral valve prolapse and systemic abnormalities of connective tissue a phenotypic continuum
    • Glesby M.J., & Pyeritz R.E. Association of mitral valve prolapse and systemic abnormalities of connective tissue. A phenotypic continuum. J. Am. Med. Assoc. 262, 523-528 (1989
    • (1989) J. Am. Med. Assoc , vol.262 , pp. 523-528
    • Glesby, M.J.1    Pyeritz, R.E.2
  • 12
    • 81855207299 scopus 로고    scopus 로고
    • The mitral valve in hypertrophic cardiomyopathy: Old versus new concepts
    • Hagège A.A., et al. The mitral valve in hypertrophic cardiomyopathy: old versus new concepts. J. Cardiovasc. Transl. Res. 4, 757-766 (2011
    • (2011) J. Cardiovasc. Transl. Res , vol.4 , pp. 757-766
    • Hagège, A.A.1
  • 13
    • 33846035657 scopus 로고    scopus 로고
    • Mutations in the gene encoding filamin A as a cause for familial cardiac valvular dystrophy
    • Kyndt F., et al. Mutations in the gene encoding filamin A as a cause for familial cardiac valvular dystrophy. Circulation 115, 40-49 (2007
    • (2007) Circulation , vol.115 , pp. 40-49
    • Kyndt, F.1
  • 14
    • 71749092074 scopus 로고    scopus 로고
    • Tensin1 requires protein phosphatase-1α in addition to rhogap dlc-1 to control cell polarization, migration and invasion
    • Hall E.H., Daugherty A.E., Choi C.K., Horwitz A.F., & Brautigan D.L. Tensin1 requires protein phosphatase-1α in addition to RhoGAP DLC-1 to control cell polarization, migration and invasion. J. Biol. Chem. 284, 34713-34722 (2009
    • (2009) J. Biol. Chem , vol.284 , pp. 34713-34722
    • Hall, E.H.1    Daugherty, A.E.2    Choi, C.K.3    Horwitz, A.F.4    Brautigan, D.L.5
  • 15
    • 84863100707 scopus 로고    scopus 로고
    • Igfbp5 induces cell adhesion, increases cell survival and inhibits cell migration in mcf-7 human breast cancer cells
    • Sureshbabu A., et al. IGFBP5 induces cell adhesion, increases cell survival and inhibits cell migration in MCF-7 human breast cancer cells. J. Cell Sci. 125, 1693-1705 (2012
    • (2012) J. Cell Sci , vol.125 , pp. 1693-1705
    • Sureshbabu, A.1
  • 16
    • 84861494687 scopus 로고    scopus 로고
    • Somatic LMCD1 mutations promoted cell migration and tumor metastasis in hepatocellular carcinoma
    • Chang C.Y., Lin S.C., Su W.H., Ho C.M., & Jou Y.S. Somatic LMCD1 mutations promoted cell migration and tumor metastasis in hepatocellular carcinoma. Oncogene 31, 2640-2652 (2012
    • (2012) Oncogene , vol.31 , pp. 2640-2652
    • Chang, C.Y.1    Lin, S.C.2    Su, W.H.3    Ho, C.M.4    Jou, Y.S.5
  • 17
    • 74949112895 scopus 로고    scopus 로고
    • LIM and cysteine-rich domains 1 regulates cardiac hypertrophy by targeting calcineurin-nuclear factor of activated T cells signaling
    • Bian Z.Y., et al. LIM and cysteine-rich domains 1 regulates cardiac hypertrophy by targeting calcineurin-nuclear factor of activated T cells signaling. Hypertension 55, 257-263 (2010
    • (2010) Hypertension , vol.55 , pp. 257-263
    • Bian, Z.Y.1
  • 18
    • 27144544769 scopus 로고    scopus 로고
    • Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development
    • Beis D., et al. Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development. Development 132, 4193-4204 (2005
    • (2005) Development , vol.132 , pp. 4193-4204
    • Beis, D.1
  • 19
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • Schunkert H., et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat. Genet. 43, 333-338 (2011
    • (2011) Nat. Genet , vol.43 , pp. 333-338
    • Schunkert, H.1
  • 20
    • 84874471608 scopus 로고    scopus 로고
    • Mef2c regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart
    • Lockhart M.M., et al. Mef2c regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart. PLoS ONE 8, e57073 (2013
    • (2013) Plos One , vol.8 , pp. e57073
    • Lockhart, M.M.1
  • 21
    • 67650103453 scopus 로고    scopus 로고
    • Genetic variants associated with cardiac structure and function: A meta-analysis and replication of genome-wide association data
    • Vasan R.S., et al. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. J. Am. Med. Assoc. 302, 168-178 (2009
    • (2009) J. Am. Med. Assoc , vol.302 , pp. 168-178
    • Vasan, R.S.1
  • 22
    • 0020620407 scopus 로고
    • Mitral valve dysfunction in the marfan syndrome clinical and echocardiographic study of prevalence and natural history
    • Pyeritz R.E., & Wappel M.A. Mitral valve dysfunction in the Marfan syndrome. Clinical and echocardiographic study of prevalence and natural history. Am. J. Med. 74, 797-807 (1983
    • (1983) Am. J. Med , vol.74 , pp. 797-807
    • Pyeritz, R.E.1    Wappel, M.A.2
  • 23
    • 15244363856 scopus 로고    scopus 로고
    • TGF-β-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome
    • Ng C.M., et al. TGF-β-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome. J. Clin. Invest. 114, 1586-1592 (2004
    • (2004) J. Clin. Invest , vol.114 , pp. 1586-1592
    • Ng, C.M.1
  • 24
    • 0035923477 scopus 로고    scopus 로고
    • Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves
    • Rabkin E., et al. Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves. Circulation 104, 2525-2532 (2001
    • (2001) Circulation , vol.104 , pp. 2525-2532
    • Rabkin, E.1
  • 25
    • 84874078736 scopus 로고    scopus 로고
    • Quantitative analysis of mitral valve morphology in mitral valve prolapse with real-time 3-dimensional echocardiography: Importance of annular saddle shape in the pathogenesis of mitral regurgitation
    • Lee A.P., et al. Quantitative analysis of mitral valve morphology in mitral valve prolapse with real-time 3-dimensional echocardiography: importance of annular saddle shape in the pathogenesis of mitral regurgitation. Circulation 127, 832-841 (2013
    • (2013) Circulation , vol.127 , pp. 832-841
    • Lee, A.P.1
  • 26
    • 84874096874 scopus 로고    scopus 로고
    • Leducq transatlantic mitral network the unsaddled annulus: Biomechanical culprit in mitral valve prolapse?
    • Jensen M.O., Hagege A.A., Otsuji Y., Levine R.A., & Leducq Transatlantic MITRAL Network The unsaddled annulus: biomechanical culprit in mitral valve prolapse?. Circulation 127, 766-768 (2013
    • (2013) Circulation , vol.127 , pp. 766-768
    • Jensen, M.O.1    Hagege, A.A.2    Otsuji, Y.3    Levine, R.A.4
  • 27
    • 84866659103 scopus 로고    scopus 로고
    • Developmental basis for filamin-A-associated myxomatous mitral valve disease
    • Sauls K., et al. Developmental basis for filamin-A-associated myxomatous mitral valve disease. Cardiovasc. Res. 96, 109-119 (2012
    • (2012) Cardiovasc. Res , vol.96 , pp. 109-119
    • Sauls, K.1
  • 28
    • 0024423585 scopus 로고
    • Three-dimensional echocardiographic reconstruction of the mitral valve, with implications for the diagnosis of mitral valve prolapse
    • Levine R.A., et al. Three-dimensional echocardiographic reconstruction of the mitral valve, with implications for the diagnosis of mitral valve prolapse. Circulation 80, 589-598 (1989
    • (1989) Circulation , vol.80 , pp. 589-598
    • Levine, R.A.1
  • 29
    • 0023946376 scopus 로고
    • Reconsideration of echocardiographic standards for mitral valve prolapse: Lack of association between leaflet displacement isolated to the apical four-chamber view and independent echocardiographic evidence of abnormality
    • Levine R.A., Stathogiannis E., Newell J.B., Harrigan P., & Weyman A.E. Reconsideration of echocardiographic standards for mitral valve prolapse: lack of association between leaflet displacement isolated to the apical four-chamber view and independent echocardiographic evidence of abnormality. J. Am. Coll. Cardiol. 11, 1010-1019 (1988
    • (1988) J. Am. Coll. Cardiol , vol.11 , pp. 1010-1019
    • Levine, R.A.1    Stathogiannis, E.2    Newell, J.B.3    Harrigan, P.4    Weyman, A.E.5
  • 30
    • 84856478855 scopus 로고    scopus 로고
    • A linear complexity phasing method for thousands of genomes
    • Delaneau O., Marchini J., & Zagury J.F. A linear complexity phasing method for thousands of genomes. Nat. Methods 9, 179-181 (2012
    • (2012) Nat. Methods , vol.9 , pp. 179-181
    • Delaneau, O.1    Marchini, J.2    Zagury, J.F.3
  • 31
    • 34347344976 scopus 로고    scopus 로고
    • A new multipoint method for genome-wide association studies by imputation of genotypes
    • Marchini J., Howie B., Myers S., McVean G., & Donnelly P. A new multipoint method for genome-wide association studies by imputation of genotypes. Nat. Genet. 39, 906-913 (2007
    • (2007) Nat. Genet , vol.39 , pp. 906-913
    • Marchini, J.1    Howie, B.2    Myers, S.3    McVean, G.4    Donnelly, P.5
  • 32
    • 78649508578 scopus 로고    scopus 로고
    • Mach: Using sequence and genotype data to estimate haplotypes and unobserved genotypes
    • Li Y., Willer C.J., Ding J., Scheet P., & Abecasis G.R. MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet. Epidemiol. 34, 816-834 (2010
    • (2010) Genet. Epidemiol , vol.34 , pp. 816-834
    • Li, Y.1    Willer, C.J.2    Ding, J.3    Scheet, P.4    Abecasis, G.R.5
  • 33
    • 34548292504 scopus 로고    scopus 로고
    • Plink: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S., et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007
    • (2007) Am. J. Hum. Genet , vol.81 , pp. 559-575
    • Purcell, S.1
  • 35
    • 77955894071 scopus 로고    scopus 로고
    • Metal: Fast and efficient meta-analysis of genome-wide association scans
    • Willer C.J., Li Y., & Abecasis G.R. METAL: fast and efficient meta-analysis of genome-wide association scans. Bioinformatics 26, 2190-2191 (2010
    • (2010) Bioinformatics , vol.26 , pp. 2190-2191
    • Willer, C.J.1    Li, Y.2    Abecasis, G.R.3
  • 36
    • 77956586071 scopus 로고    scopus 로고
    • Locuszoom: Regional visualization of genome-wide association scan results
    • Pruim R.J., et al. LocusZoom: regional visualization of genome-wide association scan results. Bioinformatics 26, 2336-2337 (2010
    • (2010) Bioinformatics , vol.26 , pp. 2336-2337
    • Pruim, R.J.1
  • 37
    • 77953794408 scopus 로고    scopus 로고
    • Expression of the familial cardiac valvular dystrophy gene, filamin-A, during heart morphogenesis
    • Norris R.A., et al. Expression of the familial cardiac valvular dystrophy gene, filamin-A, during heart morphogenesis. Dev. Dyn. 239, 2118-2127 (2010
    • (2010) Dev. Dyn , vol.239 , pp. 2118-2127
    • Norris, R.A.1
  • 38
    • 33645729418 scopus 로고    scopus 로고
    • Notch1b and neuregulin are required for specification of central cardiac conduction tissue
    • Milan D.J., Giokas A.C., Serluca F.C., Peterson R.T., & MacRae C.A. Notch1b and neuregulin are required for specification of central cardiac conduction tissue. Development 133, 1125-1132 (2006
    • (2006) Development , vol.133 , pp. 1125-1132
    • Milan, D.J.1    Giokas, A.C.2    Serluca, F.C.3    Peterson, R.T.4    MacRae, C.A.5


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