TGF-β-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome

Journal of Clinical Investigation

Volumn 114, Issue 11, 2004, Pages 1586-1592

  Ng, Connie M ^a   Cheng, Alan ^a   Myers, Loretha A ^a   Martinez Murillo, Francisco ^a   Jie, Chunfa ^a   Bedja, Djahida ^a   Gabrielson, Kathleen L ^a   Hausladen, Jennifer M W ^b   Mecham, Robert P ^b   Judge, Daniel P ^a   Dietz, Harry C ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; FIBRILLIN 1; TRANSFORMING GROWTH FACTOR BETA; ACTIN BINDING PROTEIN; BONE MORPHOGENETIC PROTEIN; FIBRILLIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CELL PROLIFERATION; CELL SURVIVAL; CONNECTIVE TISSUE DISEASE; CONTROLLED STUDY; DNA MICROARRAY; FIBRILLIN 1 GENE; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE MUTATION; GENETIC DISORDER; GENETIC ENGINEERING; GENETIC VARIABILITY; HEART ATRIOVENTRICULAR VALVE; IN VIVO STUDY; MARFAN SYNDROME; MITRAL VALVE; MITRAL VALVE PROLAPSE; MOUSE; MYXOMATOSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VALVULAR HEART DISEASE; ANIMAL; C57BL MOUSE; DISEASE MODEL; FEMALE; GENETICS; HISTOLOGY; HUMAN; MALE; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHENOTYPE; PREGNANCY;

ANIMALS; BONE MORPHOGENETIC PROTEINS; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MALE; MARFAN SYNDROME; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; MITRAL VALVE; MITRAL VALVE PROLAPSE; PHENOTYPE; PREGNANCY; TRANSFORMING GROWTH FACTOR BETA;

EID: 15244363856     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200422715     Document Type: Article

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