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Volumn 34, Issue 11, 2015, Pages 2295-2305

Empirical antibiotic therapy for pneumonia in intensive care units: a multicentre, retrospective analysis of potentially pathogenic microorganisms identified by endotracheal aspirates cultures

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; CEFTAZIDIME; CEFTRIAXONE; CIPROFLOXACIN; COTRIMOXAZOLE; GENTAMICIN; MEROPENEM; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; ANTIINFECTIVE AGENT;

EID: 84944352502     PISSN: 09349723     EISSN: 14354373     Source Type: Journal    
DOI: 10.1007/s10096-015-2482-y     Document Type: Article
Times cited : (5)

References (46)
  • 1
    • 26444480583 scopus 로고    scopus 로고
    • Clinical and economic consequences of ventilator-associated pneumonia: a systematic review
    • PID: 1621536
    • Safdar N, Dezfulian C, Collard HR, Saint S (2005) Clinical and economic consequences of ventilator-associated pneumonia: a systematic review. Crit Care Med 33(10):2184–2193
    • (2005) Crit Care Med , vol.33 , Issue.10 , pp. 2184-2193
    • Safdar, N.1    Dezfulian, C.2    Collard, H.R.3    Saint, S.4
  • 3
    • 30744446028 scopus 로고    scopus 로고
    • Appropriateness and delay to initiate therapy in ventilator-associated pneumonia
    • COI: 1:STN:280:DC%2BD28%2FgtFentg%3D%3D, PID: 1638794
    • Luna CM, Aruj P, Niederman MS, Garzón J, Violi D, Prignoni A, Ríos F, Baquero S, Gando S; Grupo Argentino de Estudio de la Neumonía Asociada al Respirador group (2006) Appropriateness and delay to initiate therapy in ventilator-associated pneumonia. Eur Respir J 27(1):158–164
    • (2006) Eur Respir J , vol.27 , Issue.1 , pp. 158-164
    • Luna, C.M.1    Aruj, P.2    Niederman, M.S.3    Garzón, J.4    Violi, D.5    Prignoni, A.6    Ríos, F.7    Baquero, S.8    Gando, S.9
  • 4
    • 0035916299 scopus 로고    scopus 로고
    • Antibiotic resistance in the intensive care unit
    • COI: 1:STN:280:DC%2BD3M7ktl2rsw%3D%3D, PID: 1118284
    • Kollef MH, Fraser VJ (2001) Antibiotic resistance in the intensive care unit. Ann Intern Med 134(4):298–314
    • (2001) Ann Intern Med , vol.134 , Issue.4 , pp. 298-314
    • Kollef, M.H.1    Fraser, V.J.2
  • 5
    • 84858802951 scopus 로고    scopus 로고
    • Policy statement on antimicrobial stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS)
    • Society for Healthcare Epidemiology of America; Infectious Diseases Society of America; Pediatric Infectious Diseases Society (2012) Policy statement on antimicrobial stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS). Infect Control Hosp Epidemiol 33(4):322–327
    • (2012) Infect Control Hosp Epidemiol , vol.33 , Issue.4 , pp. 322-327
  • 6
    • 13644269309 scopus 로고    scopus 로고
    • Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia
    • American Thoracic Society; Infectious Diseases Society of America (2005) Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 171(4):388–416
    • (2005) Am J Respir Crit Care Med , vol.171 , Issue.4 , pp. 388-416
  • 7
    • 0023180510 scopus 로고
    • Early onset pneumonia: a multicenter study in intensive care units
    • COI: 1:STN:280:DyaL1c%2FgvVKisA%3D%3D, PID: 365509
    • Langer M, Cigada M, Mandelli M, Mosconi P, Tognoni G (1987) Early onset pneumonia: a multicenter study in intensive care units. Intensive Care Med 13(5):342–346
    • (1987) Intensive Care Med , vol.13 , Issue.5 , pp. 342-346
    • Langer, M.1    Cigada, M.2    Mandelli, M.3    Mosconi, P.4    Tognoni, G.5
  • 8
    • 84879369871 scopus 로고    scopus 로고
    • Comparison of the bacterial etiology of early-onset and late-onset ventilator-associated pneumonia in subjects enrolled in 2 large clinical studies
    • PID: 2330782
    • Restrepo MI, Peterson J, Fernandez JF, Qin Z, Fisher AC, Nicholson SC (2013) Comparison of the bacterial etiology of early-onset and late-onset ventilator-associated pneumonia in subjects enrolled in 2 large clinical studies. Respir Care 58(7):1220–1225
    • (2013) Respir Care , vol.58 , Issue.7 , pp. 1220-1225
    • Restrepo, M.I.1    Peterson, J.2    Fernandez, J.F.3    Qin, Z.4    Fisher, A.C.5    Nicholson, S.C.6
  • 11
    • 67649984939 scopus 로고    scopus 로고
    • Early- and late-onset pneumonia: is this still a useful classification?
    • COI: 1:CAS:528:DC%2BD1MXotlWqtLs%3D, PID: 1936485
    • Gastmeier P, Sohr D, Geffers C, Rüden H, Vonberg RP, Welte T (2009) Early- and late-onset pneumonia: is this still a useful classification? Antimicrob Agents Chemother 53(7):2714–2718
    • (2009) Antimicrob Agents Chemother , vol.53 , Issue.7 , pp. 2714-2718
    • Gastmeier, P.1    Sohr, D.2    Geffers, C.3    Rüden, H.4    Vonberg, R.P.5    Welte, T.6
  • 12
    • 84861849037 scopus 로고    scopus 로고
    • Ventilator associated pneumonia
    • PID: 2264520
    • Hunter JD (2012) Ventilator associated pneumonia. BMJ 344:e3325
    • (2012) BMJ , vol.344 , pp. 3325
    • Hunter, J.D.1
  • 13
    • 84884211665 scopus 로고    scopus 로고
    • Value of lower respiratory tract surveillance cultures to predict bacterial pathogens in ventilator-associated pneumonia: systematic review and diagnostic test accuracy meta-analysis
    • PID: 2318846
    • Brusselaers N, Labeau S, Vogelaers D, Blot S (2013) Value of lower respiratory tract surveillance cultures to predict bacterial pathogens in ventilator-associated pneumonia: systematic review and diagnostic test accuracy meta-analysis. Intensive Care Med 39(3):365–375
    • (2013) Intensive Care Med , vol.39 , Issue.3 , pp. 365-375
    • Brusselaers, N.1    Labeau, S.2    Vogelaers, D.3    Blot, S.4
  • 14
    • 40849087901 scopus 로고    scopus 로고
    • Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: diagnosis and treatment
    • PID: 1835943
    • Muscedere J, Dodek P, Keenan S, Fowler R, Cook D, Heyland D; VAP Guidelines Committee and the Canadian Critical Care Trials Group (2008) Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: diagnosis and treatment. J Crit Care 23(1):138–147
    • (2008) J Crit Care , vol.23 , Issue.1 , pp. 138-147
    • Muscedere, J.1    Dodek, P.2    Keenan, S.3    Fowler, R.4    Cook, D.5    Heyland, D.6
  • 16
    • 84904087176 scopus 로고    scopus 로고
    • Development of antibiotic treatment algorithms based on local ecology and respiratory surveillance cultures to restrict the use of broad-spectrum antimicrobial drugs in the treatment of hospital-acquired pneumonia in the intensive care unit: a retrospective analysis
    • PID: 2503027
    • De Bus L, Saerens L, Gadeyne B, Boelens J, Claeys G, De Waele JJ, Benoit DD, Decruyenaere J, Depuydt PO (2014) Development of antibiotic treatment algorithms based on local ecology and respiratory surveillance cultures to restrict the use of broad-spectrum antimicrobial drugs in the treatment of hospital-acquired pneumonia in the intensive care unit: a retrospective analysis. Crit Care 18(4):R152
    • (2014) Crit Care , vol.18 , Issue.4 , pp. 152
    • De Bus, L.1    Saerens, L.2    Gadeyne, B.3    Boelens, J.4    Claeys, G.5    De Waele, J.J.6    Benoit, D.D.7    Decruyenaere, J.8    Depuydt, P.O.9
  • 18
    • 84944355594 scopus 로고    scopus 로고
    • Antimicrobial Resistance Surveillance in Europe. Annual report of the European Antimicrobial Resistance Surveillance Network (EARS-Net)
    • Stockholm: Swede
    • European Centre for Disease Prevention and Control (ECDC) (2013) Antimicrobial Resistance Surveillance in Europe. Annual report of the European Antimicrobial Resistance Surveillance Network (EARS-Net), 2012. Stockholm, Sweden
    • (2013) 2012
  • 19
    • 84878936279 scopus 로고    scopus 로고
    • Benchmarking inappropriate empirical antibiotic treatment
    • COI: 1:STN:280:DC%2BC38fgslGlsQ%3D%3D, PID: 2280553
    • Kariv G, Paul M, Shani V, Muchtar E, Leibovici L (2013) Benchmarking inappropriate empirical antibiotic treatment. Clin Microbiol Infect 19(7):629–633
    • (2013) Clin Microbiol Infect , vol.19 , Issue.7 , pp. 629-633
    • Kariv, G.1    Paul, M.2    Shani, V.3    Muchtar, E.4    Leibovici, L.5
  • 21
    • 85018051863 scopus 로고    scopus 로고
    • Nethmap 2012: consumption of antimicrobial agents and antimicrobial resistance among medically important bacteria in the Netherlands
    • National Institute for Public Health and the Environment (SWAB) TDWPoAP (2012) Nethmap 2012: consumption of antimicrobial agents and antimicrobial resistance among medically important bacteria in the Netherlands. pp 1–63
    • (2012) pp 1–63
  • 22
    • 33845693544 scopus 로고    scopus 로고
    • A randomized trial of diagnostic techniques for ventilator-associated pneumonia
    • Canadian Critical Care Trials Group (2006) A randomized trial of diagnostic techniques for ventilator-associated pneumonia. N Engl J Med 355(25):2619–2630
    • (2006) N Engl J Med , vol.355 , Issue.25 , pp. 2619-2630
  • 24
    • 85018088445 scopus 로고    scopus 로고
    • Ventilator-associated events: surveillance protocol
    • Centers for Disease Prevention and Control (CDC); National Healthcare Safety Network (NHSN) (2013) Ventilator-associated events: surveillance protocol. Available online at: http://www.cdc.gov/nhsn/PDFs/pscManual/10-VAE_FINAL.pdf
    • (2013) Available online at:
  • 25
    • 84887236842 scopus 로고    scopus 로고
    • Outbreak of Stenotrophomonas maltophilia on an intensive care unit
    • COI: 1:STN:280:DC%2BC2c%2FovVyktQ%3D%3D, PID: 2414836
    • Guyot A, Turton JF, Garner D (2013) Outbreak of Stenotrophomonas maltophilia on an intensive care unit. J Hosp Infect 85(4):303–307
    • (2013) J Hosp Infect , vol.85 , Issue.4 , pp. 303-307
    • Guyot, A.1    Turton, J.F.2    Garner, D.3
  • 26
    • 84893044756 scopus 로고    scopus 로고
    • New strategies against Stenotrophomonas maltophilia: a serious worldwide intrinsically drug-resistant opportunistic pathogen
    • COI: 1:CAS:528:DC%2BC2cXht1OrsbY%3D, PID: 2430871
    • Brooke JS (2014) New strategies against Stenotrophomonas maltophilia: a serious worldwide intrinsically drug-resistant opportunistic pathogen. Expert Rev Anti Infect Ther 12(1):1–4
    • (2014) Expert Rev Anti Infect Ther , vol.12 , Issue.1 , pp. 1-4
    • Brooke, J.S.1
  • 28
    • 0032810805 scopus 로고    scopus 로고
    • Guidelines for severe community-acquired pneumonia in the western world
    • COI: 1:STN:280:DyaK1MvjvVCrtw%3D%3D, PID: 1050906
    • Vegelin AL, Bissumbhar P, Joore JC, Lammers JW, Hoepelman IM (1999) Guidelines for severe community-acquired pneumonia in the western world. Neth J Med 55(3):110–117
    • (1999) Neth J Med , vol.55 , Issue.3 , pp. 110-117
    • Vegelin, A.L.1    Bissumbhar, P.2    Joore, J.C.3    Lammers, J.W.4    Hoepelman, I.M.5
  • 29
    • 77049125905 scopus 로고    scopus 로고
    • Patterns of antimicrobial therapy in severe nosocomial infections: empiric choices, proportion of appropriate therapy, and adaptation rates—a multicentre, observational survey in critically ill patients
    • Vogelaers D, De Bels D, Forêt F, Cran S, Gilbert E, Schoonheydt K, Blot S; ANTHICUS Study Investigators (2010) Patterns of antimicrobial therapy in severe nosocomial infections: empiric choices, proportion of appropriate therapy, and adaptation rates—a multicentre, observational survey in critically ill patients. Int J Antimicrob Agents 35(4):375–381
    • (2010) Int J Antimicrob Agents , vol.35 , Issue.4 , pp. 375-381
    • Vogelaers, D.1    De Bels, D.2    Forêt, F.3    Cran, S.4    Gilbert, E.5    Schoonheydt, K.6    Blot, S.7    Study Investigators, A.N.T.H.I.C.U.S.8
  • 30
    • 84918505630 scopus 로고    scopus 로고
    • Ventilator-associated pneumonia: present understanding and ongoing debates
    • PID: 2542786
    • Nair GB, Niederman MS (2015) Ventilator-associated pneumonia: present understanding and ongoing debates. Intensive Care Med 41(1):34–48
    • (2015) Intensive Care Med , vol.41 , Issue.1 , pp. 34-48
    • Nair, G.B.1    Niederman, M.S.2
  • 31
    • 84897579966 scopus 로고    scopus 로고
    • Surveillance cultures in healthcare-associated pneumonia: sense or nonsense?
    • PID: 2461424
    • Scholte JB, van Mook WN, Linssen CF (2014) Surveillance cultures in healthcare-associated pneumonia: sense or nonsense? Curr Opin Pulm Med 20(3):259–271
    • (2014) Curr Opin Pulm Med , vol.20 , Issue.3 , pp. 259-271
    • Scholte, J.B.1    van Mook, W.N.2    Linssen, C.F.3
  • 32
    • 80052514361 scopus 로고    scopus 로고
    • Penetration of anti-infective agents into pulmonary epithelial lining fluid: focus on antibacterial agents
    • COI: 1:CAS:528:DC%2BC3MXhsVWrsbzM, PID: 2189503
    • Rodvold KA, George JM, Yoo L (2011) Penetration of anti-infective agents into pulmonary epithelial lining fluid: focus on antibacterial agents. Clin Pharmacokinet 50(10):637–664
    • (2011) Clin Pharmacokinet , vol.50 , Issue.10 , pp. 637-664
    • Rodvold, K.A.1    George, J.M.2    Yoo, L.3
  • 33
    • 84867896898 scopus 로고    scopus 로고
    • Cisplatin and aminoglycoside antibiotics: hearing loss and its prevention
    • COI: 1:CAS:528:DC%2BC38XhsFGqtrf
    • Schacht J, Talaska AE, Rybak LP (2012) Cisplatin and aminoglycoside antibiotics: hearing loss and its prevention. Anat Rec (Hoboken) 295(11):1837–1850
    • (2012) Anat Rec (Hoboken) , vol.295 , Issue.11 , pp. 1837-1850
    • Schacht, J.1    Talaska, A.E.2    Rybak, L.P.3
  • 34
    • 0031013486 scopus 로고    scopus 로고
    • Aminoglycoside nephrotoxicity
    • COI: 1:CAS:528:DyaK2sXhtVyit7s%3D, PID: 900054
    • Swan SK (1997) Aminoglycoside nephrotoxicity. Semin Nephrol 17(1):27–33
    • (1997) Semin Nephrol , vol.17 , Issue.1 , pp. 27-33
    • Swan, S.K.1
  • 35
    • 0021341393 scopus 로고
    • Aminoglycoside toxicity—a review of clinical studies published between 1975 and 1982
    • PID: 636588
    • Kahlmeter G, Dahlager JI (1984) Aminoglycoside toxicity—a review of clinical studies published between 1975 and 1982. J Antimicrob Chemother 13(Suppl A):9–22
    • (1984) J Antimicrob Chemother , vol.13 , pp. 9-22
    • Kahlmeter, G.1    Dahlager, J.I.2
  • 36
    • 0242355075 scopus 로고    scopus 로고
    • Fluoroquinolones and the risk for methicillin-resistant Staphylococcus aureus in hospitalized patients
    • PID: 1471808
    • Weber SG, Gold HS, Hooper DC, Karchmer AW, Carmeli Y (2003) Fluoroquinolones and the risk for methicillin-resistant Staphylococcus aureus in hospitalized patients. Emerg Infect Dis 9(11):1415–1422
    • (2003) Emerg Infect Dis , vol.9 , Issue.11 , pp. 1415-1422
    • Weber, S.G.1    Gold, H.S.2    Hooper, D.C.3    Karchmer, A.W.4    Carmeli, Y.5
  • 38
    • 33749837901 scopus 로고    scopus 로고
    • Is there significant regional variation in hospital antibiotic consumption in Germany?
    • PID: 1703375
    • de With K, Steib-Bauert M, Straach P, Kern WV (2006) Is there significant regional variation in hospital antibiotic consumption in Germany? Infection 34(5):274–277
    • (2006) Infection , vol.34 , Issue.5 , pp. 274-277
    • de With, K.1    Steib-Bauert, M.2    Straach, P.3    Kern, W.V.4
  • 39
    • 84908674219 scopus 로고    scopus 로고
    • Association between bacterial resistance and antimicrobial consumption
    • Chaouch C, Hassairi A, Riba M, Boujaafar N (2014) Association between bacterial resistance and antimicrobial consumption. Ann Biol Clin (Paris) 72(5):555–560
    • (2014) Ann Biol Clin (Paris) , vol.72 , Issue.5 , pp. 555-560
    • Chaouch, C.1    Hassairi, A.2    Riba, M.3    Boujaafar, N.4
  • 40
    • 84880750979 scopus 로고    scopus 로고
    • Antibiotic consumption and resistance: data from Europe and Germany
    • PID: 2372739
    • Meyer E, Gastmeier P, Deja M, Schwab F (2013) Antibiotic consumption and resistance: data from Europe and Germany. Int J Med Microbiol 303(6–7):388–395
    • (2013) Int J Med Microbiol , vol.303 , Issue.6-7 , pp. 388-395
    • Meyer, E.1    Gastmeier, P.2    Deja, M.3    Schwab, F.4
  • 41
    • 77955471006 scopus 로고    scopus 로고
    • Rotation of antimicrobial therapy in the intensive care unit: impact on incidence of ventilator-associated pneumonia caused by antibiotic-resistant Gram-negative bacteria
    • COI: 1:CAS:528:DC%2BC3cXpsVKltbc%3D, PID: 2052413
    • Raineri E, Crema L, Dal Zoppo S, Acquarolo A, Pan A, Carnevale G, Albertario F, Candiani A (2010) Rotation of antimicrobial therapy in the intensive care unit: impact on incidence of ventilator-associated pneumonia caused by antibiotic-resistant Gram-negative bacteria. Eur J Clin Microbiol Infect Dis 29(8):1015–1024
    • (2010) Eur J Clin Microbiol Infect Dis , vol.29 , Issue.8 , pp. 1015-1024
    • Raineri, E.1    Crema, L.2    Dal Zoppo, S.3    Acquarolo, A.4    Pan, A.5    Carnevale, G.6    Albertario, F.7    Candiani, A.8
  • 42
    • 33845949945 scopus 로고    scopus 로고
    • The impact of an antibiotic cycling program on empirical therapy for Gram-negative infections
    • PID: 1716698
    • Merz LR, Warren DK, Kollef MH, Fridkin SK, Fraser VJ (2006) The impact of an antibiotic cycling program on empirical therapy for Gram-negative infections. Chest 130(6):1672–1678
    • (2006) Chest , vol.130 , Issue.6 , pp. 1672-1678
    • Merz, L.R.1    Warren, D.K.2    Kollef, M.H.3    Fridkin, S.K.4    Fraser, V.J.5
  • 43
    • 1642451863 scopus 로고    scopus 로고
    • Effect of an intensive care unit rotating empiric antibiotic schedule on the development of hospital-acquired infections on the non-intensive care unit ward
    • PID: 1470755
    • Hughes MG, Evans HL, Chong TW, Smith RL, Raymond DP, Pelletier SJ, Pruett TL, Sawyer RG (2004) Effect of an intensive care unit rotating empiric antibiotic schedule on the development of hospital-acquired infections on the non-intensive care unit ward. Crit Care Med 32(1):53–60
    • (2004) Crit Care Med , vol.32 , Issue.1 , pp. 53-60
    • Hughes, M.G.1    Evans, H.L.2    Chong, T.W.3    Smith, R.L.4    Raymond, D.P.5    Pelletier, S.J.6    Pruett, T.L.7    Sawyer, R.G.8
  • 44
    • 33747595580 scopus 로고    scopus 로고
    • Using local microbiologic data to develop institution-specific guidelines for the treatment of hospital-acquired pneumonia
    • PID: 1696367
    • Beardsley JR, Williamson JC, Johnson JW, Ohl CA, Karchmer TB, Bowton DL (2006) Using local microbiologic data to develop institution-specific guidelines for the treatment of hospital-acquired pneumonia. Chest 130(3):787–793
    • (2006) Chest , vol.130 , Issue.3 , pp. 787-793
    • Beardsley, J.R.1    Williamson, J.C.2    Johnson, J.W.3    Ohl, C.A.4    Karchmer, T.B.5    Bowton, D.L.6
  • 45
    • 84871638930 scopus 로고    scopus 로고
    • Locally derived versus guideline-based approach to treatment of hospital-acquired pneumonia in the trauma intensive care unit
    • Becher RD, Hoth JJ, Rebo JJ, Kendall JL, Miller PR (2012) Locally derived versus guideline-based approach to treatment of hospital-acquired pneumonia in the trauma intensive care unit. Surg Infect (Larchmt) 13(6):352–359
    • (2012) Surg Infect (Larchmt) , vol.13 , Issue.6 , pp. 352-359
    • Becher, R.D.1    Hoth, J.J.2    Rebo, J.J.3    Kendall, J.L.4    Miller, P.R.5
  • 46
    • 33847676508 scopus 로고    scopus 로고
    • Analysis and presentation of cumulative antibiograms: a new consensus guideline from the Clinical and Laboratory Standards Institute
    • PID: 1730446
    • Hindler JF, Stelling J (2007) Analysis and presentation of cumulative antibiograms: a new consensus guideline from the Clinical and Laboratory Standards Institute. Clin Infect Dis 44(6):867–873
    • (2007) Clin Infect Dis , vol.44 , Issue.6 , pp. 867-873
    • Hindler, J.F.1    Stelling, J.2


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