Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 95, Issue , 2015, Pages 136-143

  Boegh, Marie ^a   García Díaz, María ^a   Müllertz, Anette ^a   Nielsen, Hanne Mørck ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Biosimilar mucus; Caco 2 cell culture model; Diffusion; Diffusive wave spectroscopy; Mucosal drug delivery; Nanoparticles; Oral; Peptides

Indexed keywords

DESMOPRESSIN; OCTREOTIDE; PLECTASIN; ANTIMICROBIAL CATIONIC PEPTIDE; BIOSIMILAR AGENT; BOVINE SERUM ALBUMIN; NOVICIDIN; PEPTIDE FRAGMENT;

ANIMAL CELL; ARTICLE; CACO 2 CELL LINE; CELL VIABILITY; CONTROLLED STUDY; DIFFUSION; DIFFUSIVE WAVE SPECTROSCOPY; DRUG DELIVERY SYSTEM; FATTY ACID ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; INTESTINAL MUCUS; INTESTINE MUCOSA; NONHUMAN; PHYSICAL CHEMISTRY; PIG; SPECTROSCOPY; ANIMAL; BOVINE; CHEMISTRY; HUMAN; INTESTINE ABSORPTION; METABOLISM; MUCUS; PERMEABILITY; PHYSIOLOGY;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BIOSIMILAR PHARMACEUTICALS; CACO-2 CELLS; CATTLE; DIFFUSION; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; MUCUS; PEPTIDE FRAGMENTS; PERMEABILITY; SERUM ALBUMIN, BOVINE; SWINE;

EID: 84944277960     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.01.014     Document Type: Article

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