Intestine-specific MTP and global ACAT2 deficiency lowers acute cholesterol absorption with chylomicrons and HDLs

Journal of Lipid Research

Volumn 55, Issue 11, 2014, Pages 2261-2275

  Iqbal, Jahangir ^a,b   Boutjdir, Mohamed ^a,b   Rudel, Lawrence L ^c   Hussain, M Mahmood ^a,b  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Acyl CoA:cholesterol acyltransferase 2; Chylomicrons; High density lipoproteins; Microsomal triglyceride transfer protein

Indexed keywords

CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ACYLTRANSFERASE 2; CHYLOMICRON; HIGH DENSITY LIPOPROTEIN; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ACETYL COENZYME A ACETYLTRANSFERASE; CARRIER PROTEIN; CHOLESTEROL INTAKE; FAT INTAKE; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME INHIBITION; FATTY LIVER; HYPERTRIGLYCERIDEMIA; INTESTINE ABSORPTION; KNOCKOUT MOUSE; LIPID ABSORPTION; LIPID TRANSPORT; LIPOPROTEIN SYNTHESIS; LIVER METABOLISM; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN DIET; ADVERSE EFFECTS; ANIMAL; ANTIBODY SPECIFICITY; BLOOD; CHOLESTEROL INTAKE; DEFICIENCY; FAT INTAKE; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENETICS; INTESTINE; INTESTINE CELL; LIVER; METABOLISM; SECRETION (PROCESS);

ACETYL-COA C-ACETYLTRANSFERASE; ANIMALS; CARRIER PROTEINS; CHOLESTEROL; CHOLESTEROL, DIETARY; CHYLOMICRONS; DIET, WESTERN; DIETARY FATS; ENTEROCYTES; GENE EXPRESSION REGULATION; GENE KNOCKOUT TECHNIQUES; INTESTINAL ABSORPTION; INTESTINES; LIPOPROTEINS, HDL; LIVER; MALE; MICE; ORGAN SPECIFICITY; RNA, MESSENGER;

EID: 84944258664     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M047951     Document Type: Article

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