-
2
-
-
18944395784
-
State-of-The-Art management of locally advanced head and neck cancer
-
Seiwert TY, Cohen EE: State-of-the-art management of locally advanced head and neck cancer. Br J Cancer 92: 1341-1348, 2005
-
(2005)
Br J Cancer
, vol.92
, pp. 1341-1348
-
-
Seiwert, T.Y.1
Cohen, E.E.2
-
3
-
-
42149129398
-
Head and neck cancer: Changing epidemiology, diagnosis and treatment
-
Marur S, Forastiere AA: Head and neck cancer: Changing epidemiology, diagnosis and treatment. Mayo Clin Proc 83: 489-501, 2008
-
(2008)
Mayo Clin Proc
, vol.83
, pp. 489-501
-
-
Marur, S.1
Forastiere, A.A.2
-
4
-
-
20644452264
-
Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E1395): An intergroup trial of the Eastern Cooperative Oncology Group
-
Gibson MK, Li Y, Murphy B, et al: Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E1395): An intergroup trial of the Eastern Cooperative Oncology Group. J Clin Oncol 23: 3562-3567, 2005
-
(2005)
J Clin Oncol
, vol.23
, pp. 3562-3567
-
-
Gibson, M.K.1
Li, Y.2
Murphy, B.3
-
5
-
-
33748164404
-
Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck
-
Colevas AD: Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck. J Clin Oncol 24: 2644-2652, 2006
-
(2006)
J Clin Oncol
, vol.24
, pp. 2644-2652
-
-
Colevas, A.D.1
-
6
-
-
51649085865
-
Platinum-based chemotherapy plus cetuximab in head and neck cancer
-
Vermorken JB, Mesia R, Rivera F, et al: Platinum-based chemotherapy plus cetuximab in head and neck cancer. N Engl J Med 359: 1116-1127, 2008
-
(2008)
N Engl J Med
, vol.359
, pp. 1116-1127
-
-
Vermorken, J.B.1
Mesia, R.2
Rivera, F.3
-
7
-
-
84908311901
-
Human papillomavirus and overall survival after progression of oropharyngeal squamous cell carcinoma
-
Fakhry C, Zhang Q, Nguyen-Tan PF, et al: Human papillomavirus and overall survival after progression of oropharyngeal squamous cell carcinoma. J Clin Oncol 32: 3365-3373, 2014
-
(2014)
J Clin Oncol
, vol.32
, pp. 3365-3373
-
-
Fakhry, C.1
Zhang, Q.2
Nguyen-Tan, P.F.3
-
8
-
-
84903748627
-
Prognostic significance of human papillomavirus in recurrent or metastatic head and neck cancer: An analysis of Eastern Cooperative Oncology Group trials
-
Argiris A, Li S, Ghebremichael M, et al: Prognostic significance of human papillomavirus in recurrent or metastatic head and neck cancer: An analysis of Eastern Cooperative Oncology Group trials. Ann Oncol 25: 1410-1416, 2014
-
(2014)
Ann Oncol
, vol.25
, pp. 1410-1416
-
-
Argiris, A.1
Li, S.2
Ghebremichael, M.3
-
9
-
-
0343550388
-
Salvage surgery for patients with recurrent squamous cell carcinoma of the upper aerodigestive tract: When do the ends justify the means?
-
Goodwin WJ: Salvage surgery for patients with recurrent squamous cell carcinoma of the upper aerodigestive tract: When do the ends justify the means? Laryngoscope 110: S1-S18, 2000 (suppl 93)
-
(2000)
Laryngoscope
, vol.110
, pp. S1-S18
-
-
Goodwin, W.J.1
-
10
-
-
57149121199
-
Randomized trial of postoperative reirradiation combined with chemotherapy after salvage surgery compared with salvage surgery alone in head and neck carcinoma
-
Janot F, de Raucort D, Benhamou E, et al: Randomized trial of postoperative reirradiation combined with chemotherapy after salvage surgery compared with salvage surgery alone in head and neck carcinoma. J Clin Oncol 26: 5518-5523, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 5518-5523
-
-
Janot, F.1
De Raucort, D.2
Benhamou, E.3
-
11
-
-
0031764049
-
Full-dose reirradiation for unresectable head and neck carcinoma: Experience at the Gustave-Roussy Institute in a series of 169 patients
-
De Crevoisier R, Bourhis J, Domenge C, et al: Full-dose reirradiation for unresectable head and neck carcinoma: Experience at the Gustave-Roussy Institute in a series of 169 patients. J Clin Oncol 16: 3556-3562, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 3556-3562
-
-
De Crevoisier, R.1
Bourhis, J.2
Domenge, C.3
-
12
-
-
7644226413
-
Prognostic factors and long-term survivorship in patients with recurrent or metastatic carcinoma of the head and neck
-
Argiris A, Li Y, Forastiere A: Prognostic factors and long-term survivorship in patients with recurrent or metastatic carcinoma of the head and neck. Cancer 101: 2222-2229, 2004
-
(2004)
Cancer
, vol.101
, pp. 2222-2229
-
-
Argiris, A.1
Li, Y.2
Forastiere, A.3
-
13
-
-
0017704307
-
CISDichlorodiammineplatinum( II) in the treatment of epidermoid carcinoma of the head and neck
-
Wittes RE, Cvitkovic E, Shah J, et al: CISDichlorodiammineplatinum( II) in the treatment of epidermoid carcinoma of the head and neck. Cancer Treat Rep 61: 359-366, 1977
-
(1977)
Cancer Treat Rep
, vol.61
, pp. 359-366
-
-
Wittes, R.E.1
Cvitkovic, E.2
Shah, J.3
-
14
-
-
0018568041
-
Cis- Dichlorodiammineplatinum(II)-based chemotherapy as initial treatment of advanced head and neck cancer
-
Wittes R, Heller K, Randolph V, et al: Cis- Dichlorodiammineplatinum(II)-based chemotherapy as initial treatment of advanced head and neck cancer. Cancer Treat Rep 63: 1533-1538, 1979
-
(1979)
Cancer Treat Rep
, vol.63
, pp. 1533-1538
-
-
Wittes, R.1
Heller, K.2
Randolph, V.3
-
15
-
-
0021891018
-
Cisplatinum and bleomycin for advanced or recurrent squamous cell carcinoma of the head and neck: A randomized factorial phase III controlled trial
-
Morton RP, Rugman F, Dorman EB, et al: Cisplatinum and bleomycin for advanced or recurrent squamous cell carcinoma of the head and neck: A randomized factorial phase III controlled trial. Cancer Chemother Pharmacol 15: 283-289, 1985
-
(1985)
Cancer Chemother Pharmacol
, vol.15
, pp. 283-289
-
-
Morton, R.P.1
Rugman, F.2
Dorman, E.B.3
-
16
-
-
0025012603
-
A phase III randomised trial of cisplatinum, methotrexate, cisplatinum methotrexate and cisplatin 5-FU in end stage squamous cell carcinoma of the head and neck
-
The Liverpool Head and Neck Oncology Group: A phase III randomised trial of cisplatinum, methotrexate, cisplatinum methotrexate and cisplatin 5-FU in end stage squamous cell carcinoma of the head and neck. Br J Cancer 61: 311-315, 1990
-
(1990)
Br J Cancer
, vol.61
, pp. 311-315
-
-
-
17
-
-
0021152550
-
Cisplatin and 5-fluorouracil infusion in patients with recurrent and disseminated epidermoid cancer of the head and neck
-
Kish JA, Weaver A, Jacobs J, et al: Cisplatin and 5-fluorouracil infusion in patients with recurrent and disseminated epidermoid cancer of the head and neck. Cancer 53: 1819-1824, 1984
-
(1984)
Cancer
, vol.53
, pp. 1819-1824
-
-
Kish, J.A.1
Weaver, A.2
Jacobs, J.3
-
18
-
-
0023616584
-
Combination chemotherapy with methotrexate, bleomycin, and vincristine with or without cisplatin in advanced squamous cell carcinoma of the head and neck
-
Clavel M, Cognetti F, Dodion P, et al: Combination chemotherapy with methotrexate, bleomycin, and vincristine with or without cisplatin in advanced squamous cell carcinoma of the head and neck. Cancer 60: 1173-1177, 1987
-
(1987)
Cancer
, vol.60
, pp. 1173-1177
-
-
Clavel, M.1
Cognetti, F.2
Dodion, P.3
-
19
-
-
0028318327
-
Standard chemotherapy in squamous cell head and neck cancer: What we have learned from randomized trials
-
Browman GP, Cronin L: Standard chemotherapy in squamous cell head and neck cancer: What we have learned from randomized trials. Semin Oncol 21: 311-319, 1994
-
(1994)
Semin Oncol
, vol.21
, pp. 311-319
-
-
Browman, G.P.1
Cronin, L.2
-
20
-
-
0026569931
-
A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck
-
Jacobs C, Lyman G, Velez-García E, et al: A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck. J Clin Oncol 10: 257-263, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 257-263
-
-
Jacobs, C.1
Lyman, G.2
Velez-García, E.3
-
21
-
-
0026645077
-
Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: A Southwest Oncology Group study
-
Forastiere AA, Metch B, Schuller DE, et al: Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: A Southwest Oncology Group study. J Clin Oncol 10: 1245-1251, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 1245-1251
-
-
Forastiere, A.A.1
Metch, B.2
Schuller, D.E.3
-
22
-
-
0028359951
-
Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck: A phase III study of the EORTC Head and Neck Cancer Cooperative Group
-
Clavel M, Vermorken JB, Cognetti F, et al: Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck: A phase III study of the EORTC Head and Neck Cancer Cooperative Group. Ann Oncol 5: 521-526, 1994
-
(1994)
Ann Oncol
, vol.5
, pp. 521-526
-
-
Clavel, M.1
Vermorken, J.B.2
Cognetti, F.3
-
23
-
-
0028472918
-
Docetaxel (Taxotere): An active drug for the treatment of patients with advanced squamous cell carcinoma of the head and neck-EORTC Early Clinical Trials Group
-
Catimel G, Verweij J, Mattijssen V, et al: Docetaxel (Taxotere): An active drug for the treatment of patients with advanced squamous cell carcinoma of the head and neck-EORTC Early Clinical Trials Group. Ann Oncol 5: 533-537, 1994
-
(1994)
Ann Oncol
, vol.5
, pp. 533-537
-
-
Catimel, G.1
Verweij, J.2
Mattijssen, V.3
-
24
-
-
9244261066
-
Docetaxel: An active drug for squamous cell carcinoma of the head and neck
-
Dreyfuss AI, Clark JR, Norris CM, et al: Docetaxel: An active drug for squamous cell carcinoma of the head and neck. J Clin Oncol 14: 1672-1678, 1996
-
(1996)
J Clin Oncol
, vol.14
, pp. 1672-1678
-
-
Dreyfuss, A.I.1
Clark, J.R.2
Norris, C.M.3
-
25
-
-
0032102421
-
Final report of a phase II evaluation of paclitaxel in patients with advanced squamous cell carcinoma of the head and neck: An Eastern Cooperative Oncology Group trial (PA390
-
Forastiere AA, Shank D, Neuberg D, et al: Final report of a phase II evaluation of paclitaxel in patients with advanced squamous cell carcinoma of the head and neck: An Eastern Cooperative Oncology Group trial (PA390). Cancer 82: 2270-2274, 1998
-
(1998)
Cancer
, vol.82
, pp. 2270-2274
-
-
Forastiere, A.A.1
Shank, D.2
Neuberg, D.3
-
26
-
-
10744226565
-
Paclitaxel and cisplatin in patients with recurrent and metastatic head and neck squamous cell carcinoma
-
Adamo V, Ferraro G, Pergolizzi S, et al: Paclitaxel and cisplatin in patients with recurrent and metastatic head and neck squamous cell carcinoma. Oral Oncol 40: 525-531, 2004
-
(2004)
Oral Oncol
, vol.40
, pp. 525-531
-
-
Adamo, V.1
Ferraro, G.2
Pergolizzi, S.3
-
27
-
-
0036380344
-
Phase II study with docetaxel and cisplatin in the treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck
-
Gedlicka C, Formanek M, Selzer E, et al: Phase II study with docetaxel and cisplatin in the treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck. Oncol 63: 145-150, 2002
-
(2002)
Oncol
, vol.63
, pp. 145-150
-
-
Gedlicka, C.1
Formanek, M.2
Selzer, E.3
-
28
-
-
0031897977
-
Phase II trial of paclitaxel, ifosfamide, and cisplatin in patients with recurrent head and neck squamous cell carcinoma
-
Shin DM, Glisson BS, Khuri FR, et al: Phase II trial of paclitaxel, ifosfamide, and cisplatin in patients with recurrent head and neck squamous cell carcinoma. J Clin Oncol 16: 1325-1330, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 1325-1330
-
-
Shin, D.M.1
Glisson, B.S.2
Khuri, F.R.3
-
29
-
-
0033639153
-
Combination chemotherapy with docetaxel, cisplatin, and 5-fluorouracil in previously treated patients with advanced/recurrent head and neck cancer: A phase II feasibility study
-
Janinis J, Papadakou M, Xidakis E, et al: Combination chemotherapy with docetaxel, cisplatin, and 5-fluorouracil in previously treated patients with advanced/recurrent head and neck cancer: A phase II feasibility study. Am J Clin Oncol 23: 128-131, 2000
-
(2000)
Am J Clin Oncol
, vol.23
, pp. 128-131
-
-
Janinis, J.1
Papadakou, M.2
Xidakis, E.3
-
30
-
-
0035312662
-
Phase II study of paclitaxel, ifosfamide, and carboplatin in patients with recurrent or metastatic head and neck squamous cell carcinoma
-
Shin DM, Khuri FR, Glisson BS, et al: Phase II study of paclitaxel, ifosfamide, and carboplatin in patients with recurrent or metastatic head and neck squamous cell carcinoma. Cancer 91: 1316-1323, 2001
-
(2001)
Cancer
, vol.91
, pp. 1316-1323
-
-
Shin, D.M.1
Khuri, F.R.2
Glisson, B.S.3
-
31
-
-
6844236387
-
Phase III trial of modulation of cisplatin/fluorouracil chemotherapy by interferon alfa-2b in patients with recurrent or metastatic head and neck cancer
-
Schrijvers D, Johnson J, Jiminez U, et al: Phase III trial of modulation of cisplatin/fluorouracil chemotherapy by interferon alfa-2b in patients with recurrent or metastatic head and neck cancer. J Clin Oncol 16: 1054-1059, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 1054-1059
-
-
Schrijvers, D.1
Johnson, J.2
Jiminez, U.3
-
32
-
-
33144461661
-
Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/ recurrent head and neck cancer: An Eastern Cooperative Oncology Group study
-
Burtness B, Goldwasser MA, Flood W, et al: Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/ recurrent head and neck cancer: An Eastern Cooperative Oncology Group study. J Clin Oncol 23: 8646-8654, 2005
-
(2005)
J Clin Oncol
, vol.23
, pp. 8646-8654
-
-
Burtness, B.1
Goldwasser, M.A.2
Flood, W.3
-
33
-
-
84866524667
-
Pemetrexed in combination with cisplatin versus cisplatin monotherapy in patients with recurrent or metastatic head and neck cancer: Final results of a randomized, double-blind, placebo-controlled, phase 3 study
-
Urba S, van Herpen CM, Sahoo TP, et al: Pemetrexed in combination with cisplatin versus cisplatin monotherapy in patients with recurrent or metastatic head and neck cancer: Final results of a randomized, double-blind, placebo-controlled, phase 3 study. Cancer 118: 4694-4705, 2012
-
(2012)
Cancer
, vol.118
, pp. 4694-4705
-
-
Urba, S.1
Van Herpen, C.M.2
Sahoo, T.P.3
-
34
-
-
84866732807
-
Comparison of five cisplatin-based regimens frequently used as the first-line protocols in metastatic nasopharyngeal carcinoma
-
Jin Y, Shi YX, Cai XY, et al: Comparison of five cisplatin-based regimens frequently used as the first-line protocols in metastatic nasopharyngeal carcinoma. J Cancer Res Clin Oncol 138: 1717-1725, 2012
-
(2012)
J Cancer Res Clin Oncol
, vol.138
, pp. 1717-1725
-
-
Jin, Y.1
Shi, Y.X.2
Cai, X.Y.3
-
35
-
-
7844239779
-
An EORTC-ECSG phase II study of vinorelbine in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck
-
Degardin M, Oliveira J, Geoffrois L, et al: An EORTC-ECSG phase II study of vinorelbine in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck. Ann Oncol 9: 1103-1107, 1998
-
(1998)
Ann Oncol
, vol.9
, pp. 1103-1107
-
-
Degardin, M.1
Oliveira, J.2
Geoffrois, L.3
-
36
-
-
0031819276
-
A phase II trial of vinorelbine in patients with recurrent or metastatic squamous cell carcinoma of the head and neck
-
Saxman S, Mann B, Canfield V, et al: A phase II trial of vinorelbine in patients with recurrent or metastatic squamous cell carcinoma of the head and neck. Am J Clin Oncol 21: 398-400, 1998
-
(1998)
Am J Clin Oncol
, vol.21
, pp. 398-400
-
-
Saxman, S.1
Mann, B.2
Canfield, V.3
-
37
-
-
34848863089
-
Phase II clinical study of gemcitabine in the treatment of patients with advanced nasopharyngeal carcinoma after the failure of platinum-based chemotherapy
-
Zhang L, Zhang Y, Huang PY, et al: Phase II clinical study of gemcitabine in the treatment of patients with advanced nasopharyngeal carcinoma after the failure of platinum-based chemotherapy. Cancer Chemother Pharmacol 61: 33-38, 2008
-
(2008)
Cancer Chemother Pharmacol
, vol.61
, pp. 33-38
-
-
Zhang, L.1
Zhang, Y.2
Huang, P.Y.3
-
38
-
-
0027183870
-
Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer
-
Rubin Grandis JR, Tweardy DJ: Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer. Cancer Res 53: 3579-3584, 1993
-
(1993)
Cancer Res
, vol.53
, pp. 3579-3584
-
-
Rubin Grandis, J.R.1
Tweardy, D.J.2
-
39
-
-
0032478998
-
Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival
-
Rubin Grandis J, Melhem MF, Gooding WE, et al: Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst 90: 824-832, 1998
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 824-832
-
-
Rubin Grandis, J.1
Melhem, M.F.2
Gooding, W.E.3
-
40
-
-
0037115674
-
Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma
-
Ang KK, Berkey BA, Tu X, et al: Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma. Cancer Res 62: 7350-7356, 2002
-
(2002)
Cancer Res
, vol.62
, pp. 7350-7356
-
-
Ang, K.K.1
Berkey, B.A.2
Tu, X.3
-
41
-
-
84859483100
-
Phase II study of the combination of cetuximab and weekly paclitaxel in the first-line treatment of patients with recurrent and/or metastatic squamous cell carcinoma of head and neck
-
Hitt R, Irigoyen A, Cortes-Funes H, et al: Phase II study of the combination of cetuximab and weekly paclitaxel in the first-line treatment of patients with recurrent and/or metastatic squamous cell carcinoma of head and neck. Ann Oncol 23: 1016-1022, 2012
-
(2012)
Ann Oncol
, vol.23
, pp. 1016-1022
-
-
Hitt, R.1
Irigoyen, A.2
Cortes-Funes, H.3
-
42
-
-
34250180582
-
Openlabel, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy
-
Vermorken JB, Trigo J, Hitt R, et al: Openlabel, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy. J Clin Oncol 25: 2171-2177, 2007
-
(2007)
J Clin Oncol
, vol.25
, pp. 2171-2177
-
-
Vermorken, J.B.1
Trigo, J.2
Hitt, R.3
-
43
-
-
84879785532
-
Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): An open-label phase 3 randomised trial
-
Vermorken JB, Stöhlmacher-Williams J, Davidenko I, et al: Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): An open-label phase 3 randomised trial. Lancet Oncol 14: 697-710, 2013
-
(2013)
Lancet Oncol
, vol.14
, pp. 697-710
-
-
Vermorken, J.B.1
Stöhlmacher-Williams, J.2
Davidenko, I.3
-
44
-
-
84888064205
-
PARTNER: A randomized phase II study of docetaxel/cisplatin (doc/cis) chemotherapy with or without panitumumab (pmab) as first-line treatment (tx) for recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN
-
abstr 6029
-
Wirth LJ, Dakhil SR, Kornek G, et al: PARTNER: A randomized phase II study of docetaxel/cisplatin (doc/cis) chemotherapy with or without panitumumab (pmab) as first-line treatment (tx) for recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN). J Clin Oncol 31, 2013 (suppl 15s; abstr 6029)
-
(2013)
J Clin Oncol
, vol.31
-
-
Wirth, L.J.1
Dakhil, S.R.2
Kornek, G.3
-
45
-
-
79953183347
-
Zalutumumab plus best supportive care versus best supportive care alone in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after failure of platinum-based chemotherapy: An open-label, randomized phase 3 trial
-
Machiels JP, Subramanian S, Ruzsa A, et al: Zalutumumab plus best supportive care versus best supportive care alone in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after failure of platinum-based chemotherapy: An open-label, randomized phase 3 trial. Lancet Oncol 12: 333-343, 2011
-
(2011)
Lancet Oncol
, vol.12
, pp. 333-343
-
-
Machiels, J.P.1
Subramanian, S.2
Ruzsa, A.3
-
46
-
-
64649097892
-
Phase III study of gefitinib compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck
-
Stewart JS, Cohen EE, Licitra L, et al: Phase III study of gefitinib compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck. J Clin Oncol 27: 1864-1871, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 1864-1871
-
-
Stewart, J.S.1
Cohen, E.E.2
Licitra, L.3
-
47
-
-
84876073132
-
Phase III randomized, placebo-controlled trial of docetaxel with or without gefitinib in recurrent or metastatic head and neck cancer: An Eastern Cooperative Oncology Group trial
-
Argiris A, Ghebremichael M, Gilbert J, et al: Phase III randomized, placebo-controlled trial of docetaxel with or without gefitinib in recurrent or metastatic head and neck cancer: An Eastern Cooperative Oncology Group trial. J Clin Oncol 31: 1405-1414, 2013
-
(2013)
J Clin Oncol
, vol.31
, pp. 1405-1414
-
-
Argiris, A.1
Ghebremichael, M.2
Gilbert, J.3
-
48
-
-
1842772526
-
Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck
-
Soulieres D, Senzer NN, Vokes EE, et al: Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck. J Clin Oncol 22: 77-85, 2004
-
(2004)
J Clin Oncol
, vol.22
, pp. 77-85
-
-
Soulieres, D.1
Senzer, N.N.2
Vokes, E.E.3
-
49
-
-
84859873106
-
A phase II study of lapatinib in recurrent/metastatic squamous cell carcinoma of the head and neck
-
de Souza JA, Davis DW, Zhang Y, et al: A phase II study of lapatinib in recurrent/metastatic squamous cell carcinoma of the head and neck. Clin Cancer Res 18: 2336-2343, 2012
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2336-2343
-
-
De Souza, J.A.1
Davis, D.W.2
Zhang, Y.3
-
50
-
-
84903764970
-
A randomized, phase II study of afatinib versus cetuximab in metastatic or recurrent squamous cell carcinoma of the head and neck
-
Seiwert TY, Fayette J, Cupissol D, et al: A randomized, phase II study of afatinib versus cetuximab in metastatic or recurrent squamous cell carcinoma of the head and neck. Ann Oncol 25: 1813-1820, 2014
-
(2014)
Ann Oncol
, vol.25
, pp. 1813-1820
-
-
Seiwert, T.Y.1
Fayette, J.2
Cupissol, D.3
-
51
-
-
85024120447
-
Afatinib versus methotrexate as second-line treatment for patient with R/M HNSCC who progressed after platinum-based therapy: Primary efficacy results of LUX-Head & Neck 1, a phase III trial
-
Presented at the Madrid, Spain, September 26-30
-
Machiels J, Haddad RI, Fayette J, et al: Afatinib versus methotrexate as second-line treatment for patient with R/M HNSCC who progressed after platinum-based therapy: Primary efficacy results of LUX-Head & Neck 1, a phase III trial. Presented at the Annual Congress of the European Society for Medical Oncology, Madrid, Spain, September 26-30, 2014
-
(2014)
Annual Congress of the European Society for Medical Oncology
-
-
Machiels, J.1
Haddad, R.I.2
Fayette, J.3
-
52
-
-
84874569165
-
A phase II trial of dacomitinib, an oral pan-human EGF receptor (HER) inhibitor, as first-line treatment in recurrent and/or metastatic squamous-cell carcinoma of the head and neck
-
Abdul Razak AR, Soulières D, Laurie SA, et al: A phase II trial of dacomitinib, an oral pan-human EGF receptor (HER) inhibitor, as first-line treatment in recurrent and/or metastatic squamous-cell carcinoma of the head and neck. Ann Oncol 24: 761-769, 2013
-
(2013)
Ann Oncol
, vol.24
, pp. 761-769
-
-
Abdul Razak, A.R.1
Soulières, D.2
Laurie, S.A.3
-
53
-
-
84964194350
-
Phase II clinical and exploratory biomarker study of dacomitinib in patients with recurrent and/or metastatic squamous cell carcinoma of head and neck
-
Kim HS, Kwon HJ, Jung I, et al: Phase II clinical and exploratory biomarker study of dacomitinib in patients with recurrent and/or metastatic squamous cell carcinoma of head and neck. Clin Cancer Res 21: 544-552, 2015
-
(2015)
Clin Cancer Res
, vol.21
, pp. 544-552
-
-
Kim, H.S.1
Kwon, H.J.2
Jung, I.3
-
54
-
-
84867885308
-
Overcoming resistance to EGFR inhibitor in head and neck cancer: A review of the literature
-
Rabinowits G, Haddad RI: Overcoming resistance to EGFR inhibitor in head and neck cancer: A review of the literature. Oral Oncol 48: 1085-1089, 2012
-
(2012)
Oral Oncol
, vol.48
, pp. 1085-1089
-
-
Rabinowits, G.1
Haddad, R.I.2
-
55
-
-
79955496795
-
Evaluation of EGFR copy number as a predictive biomarker for the efficacy of cetuximab in combination with chemotherapy in the first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck: EXTREME study
-
Licitra L, Mesia R, Rivera F, et al: Evaluation of EGFR copy number as a predictive biomarker for the efficacy of cetuximab in combination with chemotherapy in the first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck: EXTREME study. Ann Oncol 22: 1078-1087, 2011
-
(2011)
Ann Oncol
, vol.22
, pp. 1078-1087
-
-
Licitra, L.1
Mesia, R.2
Rivera, F.3
-
56
-
-
84875734469
-
Predictive value of epidermal growth factor receptor expression for first-line chemotherapy plus cetuximab in patients with head and neck and colorectal cancer: Analysis of data from the EXTREME and CRYSTAL studies
-
Licitra L, Störkel S, Kerr KM, et al: Predictive value of epidermal growth factor receptor expression for first-line chemotherapy plus cetuximab in patients with head and neck and colorectal cancer: Analysis of data from the EXTREME and CRYSTAL studies. Eur J Cancer 49: 1161-1168, 2013
-
(2013)
Eur J Cancer
, vol.49
, pp. 1161-1168
-
-
Licitra, L.1
Störkel, S.2
Kerr, K.M.3
-
57
-
-
84920506775
-
Rare occurrence of EGFRvIII deletion in head and neck squamous cell carcinoma
-
Khattri A, Zuo Z, Brägelmann J, et al: Rare occurrence of EGFRvIII deletion in head and neck squamous cell carcinoma. Oral Oncol 51: 53-58, 2015
-
(2015)
Oral Oncol
, vol.51
, pp. 53-58
-
-
Khattri, A.1
Zuo, Z.2
Brägelmann, J.3
-
58
-
-
84856845213
-
Polymorphisms of the epidermal growth factor receptor (EGFR) and survival in patients with advanced cancer of the head and neck (HNSCC
-
Stoehlmacher-Williams J, Obermann L, Ehninger G, et al: Polymorphisms of the epidermal growth factor receptor (EGFR) and survival in patients with advanced cancer of the head and neck (HNSCC). Anticancer Res 32: 421-425, 2012
-
(2012)
Anticancer Res
, vol.32
, pp. 421-425
-
-
Stoehlmacher-Williams, J.1
Obermann, L.2
Ehninger, G.3
-
59
-
-
84919391192
-
EGF and EGFR genetic polymorphisms predict prognosis in locally advanced pharyngolaryngeal squamous cell carcinoma patients receiving postoperative concurrent chemoradiotherapy
-
Su NW, Leu YS, Lee JC, et al: EGF and EGFR genetic polymorphisms predict prognosis in locally advanced pharyngolaryngeal squamous cell carcinoma patients receiving postoperative concurrent chemoradiotherapy. Onco Targets Ther 7: 2197-2204, 2014
-
(2014)
Onco Targets Ther
, vol.7
, pp. 2197-2204
-
-
Su, N.W.1
Leu, Y.S.2
Lee, J.C.3
-
60
-
-
84942612703
-
Optimal management of the elderly patient with head and neck cancer: Issues regarding surgery, irradiation and chemotherapy
-
Mountzios G: Optimal management of the elderly patient with head and neck cancer: Issues regarding surgery, irradiation and chemotherapy. World J Clin Oncol 6: 7-15, 2015
-
(2015)
World J Clin Oncol
, vol.6
, pp. 7-15
-
-
Mountzios, G.1
-
61
-
-
1342289778
-
Outcome of elderly patients with recurrent or metastatic head and neck cancer treated with cisplatin-based chemotherapy
-
Argiris A, Li Y, Murphy BA, et al: Outcome of elderly patients with recurrent or metastatic head and neck cancer treated with cisplatin-based chemotherapy. J Clin Oncol 22: 262-268, 2004
-
(2004)
J Clin Oncol
, vol.22
, pp. 262-268
-
-
Argiris, A.1
Li, Y.2
Murphy, B.A.3
-
62
-
-
84929156742
-
Resection of subsequent pulmonary metastases from treated head and neck squamous cell carcinoma: Systematic review and meta-analysis
-
Young ER, Diakos E, Khalid-Raja M, et al: Resection of subsequent pulmonary metastases from treated head and neck squamous cell carcinoma: Systematic review and meta-analysis. Clin Otolaryngol 40: 208-218, 2015
-
(2015)
Clin Otolaryngol
, vol.40
, pp. 208-218
-
-
Young, E.R.1
Diakos, E.2
Khalid-Raja, M.3
-
63
-
-
84880259398
-
Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers
-
Lui VW, Hedberg ML, Li H, et al: Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers. Cancer Discov 3: 761-769, 2013
-
(2013)
Cancer Discov
, vol.3
, pp. 761-769
-
-
Lui, V.W.1
Hedberg, M.L.2
Li, H.3
-
64
-
-
84961289657
-
Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas
-
Seiwert TY, Zuo Z, Keck MK, et al: Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas. Clin Cancer Res 21: 632-641, 2015
-
(2015)
Clin Cancer Res
, vol.21
, pp. 632-641
-
-
Seiwert, T.Y.1
Zuo, Z.2
Keck, M.K.3
-
65
-
-
84933178034
-
A randomized, phase 2 trial of docetaxel with or without PX-866, an irreversible oral phosphatidylinositol 3-kinase inhibitor, in patients with relapsed or metastatic head and neck squamous cell cancer
-
Jimeno A, Bauman JE, Weissman C, et al: A randomized, phase 2 trial of docetaxel with or without PX-866, an irreversible oral phosphatidylinositol 3-kinase inhibitor, in patients with relapsed or metastatic head and neck squamous cell cancer. Oral Oncol 51: 383-388, 2015
-
(2015)
Oral Oncol
, vol.51
, pp. 383-388
-
-
Jimeno, A.1
Bauman, J.E.2
Weissman, C.3
-
66
-
-
84933180890
-
A randomized, phase II trial of cetuximab with or without PX-866, an irreversible oral phosphatidylinositol 3-kinase inhibitor, in patients with relapsed or metastatic head and neck squamous cell cancer
-
Jimeno A, Shirai K, Choi M, et al: A randomized, phase II trial of cetuximab with or without PX-866, an irreversible oral phosphatidylinositol 3-kinase inhibitor, in patients with relapsed or metastatic head and neck squamous cell cancer. Ann Oncol 26: 556-561, 2015
-
(2015)
Ann Oncol
, vol.26
, pp. 556-561
-
-
Jimeno, A.1
Shirai, K.2
Choi, M.3
-
67
-
-
84885431490
-
Safety, pharmacokinetics, and preliminary activity of the specific PI3K inhibitor BYL719: Results from the first-in-human study
-
abstr 2531
-
Gonzalez-Angulo AM, Juric D, Argiles G, et al: Safety, pharmacokinetics, and preliminary activity of the specific PI3K inhibitor BYL719: Results from the first-in-human study. J Clin Oncol 31, 2013 (suppl 18s; abstr 2531)
-
(2013)
J Clin Oncol 31
-
-
Gonzalez-Angulo, A.M.1
Juric, D.2
Argiles, G.3
-
68
-
-
84944254688
-
Phase II trial of everolimus and erlotinib in patients with platinum-resistant recurrent and/or metastatic head and neck squamous cell carcinoma
-
abstr 6067
-
Massarelli E, Ginsberg LE, Lin H, et al: Phase II trial of everolimus and erlotinib in patients with platinum-resistant recurrent and/or metastatic head and neck squamous cell carcinoma. J Clin Oncol 31, 2013 (suppl 15s; abstr 6067)
-
(2013)
J Clin Oncol
, vol.31
-
-
Massarelli, E.1
Ginsberg, L.E.2
Lin, H.3
-
69
-
-
84919339148
-
Phase 1 and pharmacokinetic study of everolimus in combination with cetuximab and carboplatin for recurrent/metastatic squamous cell carcinoma of the head and neck
-
Saba NF, Hurwitz SJ, Magliocca K, et al: Phase 1 and pharmacokinetic study of everolimus in combination with cetuximab and carboplatin for recurrent/metastatic squamous cell carcinoma of the head and neck. Cancer 120: 3940-3951, 2014
-
(2014)
Cancer
, vol.120
, pp. 3940-3951
-
-
Saba, N.F.1
Hurwitz, S.J.2
Magliocca, K.3
-
70
-
-
84863436028
-
A phase I study of temsirolimus plus carboplatin plus paclitaxel for patients with recurrent or metastatic (R/M) head and neck squamous cell cancer (HNSCC)
-
Fury MG, Sherman E, Ho A, et al: A phase I study of temsirolimus plus carboplatin plus paclitaxel for patients with recurrent or metastatic (R/M) head and neck squamous cell cancer (HNSCC). Cancer Chemother Pharmacol 70: 121-128, 2012
-
(2012)
Cancer Chemother Pharmacol
, vol.70
, pp. 121-128
-
-
Fury, M.G.1
Sherman, E.2
Ho, A.3
-
71
-
-
84944270674
-
Phase II study of temsirolimus and erlotinib in patients (pts) with recurrent/metastatic (R/M), platinum-refractory head and neck squamous cell carcinoma (HNSCC
-
abstr 5549
-
Bauman JE, Arias-Pulido H, Lee SJ, et al: Phase II study of temsirolimus and erlotinib in patients (pts) with recurrent/metastatic (R/M), platinum-refractory head and neck squamous cell carcinoma (HNSCC). J Clin Oncol 30, 2012 (suppl 15s; abstr 5549)
-
(2012)
J Clin Oncol
, vol.30
-
-
Bauman, J.E.1
Arias-Pulido, H.2
Lee, S.J.3
-
72
-
-
84933182955
-
TEMHEAD: A single-arm multicenter phase II study of temsirolimus in platin- and cetuximab-refractory recurrent and/or metastatic squamous cell carcinoma of the head and neck (SCCHN) of the German SCCHN Group (AIO)
-
Grünwald V, Keilholz U, Boehm A, et al: TEMHEAD: A single-arm multicenter phase II study of temsirolimus in platin- and cetuximab-refractory recurrent and/or metastatic squamous cell carcinoma of the head and neck (SCCHN) of the German SCCHN Group (AIO). Ann Oncol 26: 561-567, 2015
-
(2015)
Ann Oncol
, vol.26
, pp. 561-567
-
-
Grünwald, V.1
Keilholz, U.2
Boehm, A.3
-
73
-
-
84897128733
-
P62/ SQSTM1 accumulation in squamous cell carcinoma of head and neck predicts sensitivity to phosphatidylinositol 3-kinase pathway inhibitors
-
Kuo WL, Sharifi MN, Lingen MW, et al: P62/ SQSTM1 accumulation in squamous cell carcinoma of head and neck predicts sensitivity to phosphatidylinositol 3-kinase pathway inhibitors. PLoS One 9: E90171, 2014
-
(2014)
PLoS One
, vol.9
, pp. e90171
-
-
Kuo, W.L.1
Sharifi, M.N.2
Lingen, M.W.3
-
74
-
-
84907501256
-
Programmed death-ligand 1 (PD-L1) expression in various tumor types
-
Grosso J, Inzunza D, Wu Q, et al: Programmed death-ligand 1 (PD-L1) expression in various tumor types. J Immunother Cancer 1: S53, 2013 (suppl 1)
-
(2013)
J Immunother Cancer
, vol.1
, pp. S53
-
-
Grosso, J.1
Inzunza, D.2
Wu, Q.3
-
75
-
-
84875475811
-
Evidence for a role of the PD-1: PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma
-
Lyford-Pike S, Peng S, Young GD, et al: Evidence for a role of the PD-1: PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma. Cancer Res 73: 1733-1741, 2013
-
(2013)
Cancer Res
, vol.73
, pp. 1733-1741
-
-
Lyford-Pike, S.1
Peng, S.2
Young, G.D.3
-
76
-
-
84871966600
-
PD-1- expressing tumor-infiltrating T cells are a favorable prognostic biomarker in HPV-associated head and neck cancer
-
Badoual C, Hans S, Merillon N, et al: PD-1- expressing tumor-infiltrating T cells are a favorable prognostic biomarker in HPV-associated head and neck cancer. Cancer Res 73: 128-138, 2013
-
(2013)
Cancer Res
, vol.73
, pp. 128-138
-
-
Badoual, C.1
Hans, S.2
Merillon, N.3
-
77
-
-
84920993558
-
A phase Ib study of pembrolizumab (Pembo; MK-3475) in patients (Pts) with human papilloma virus (HPV)- positive and negative head and neck cancer (HNC)
-
Chow LQ, Burtness B, Weiss J, et al: A phase Ib study of pembrolizumab (Pembo; MK-3475) in patients (Pts) with human papilloma virus (HPV)- positive and negative head and neck cancer (HNC). Ann Oncol 25: S1-S41, 2014 (suppl 4)
-
(2014)
Ann Oncol
, vol.25
, pp. S1-S41
-
-
Chow, L.Q.1
Burtness, B.2
Weiss, J.3
-
78
-
-
84920937027
-
Clinical activity and safety of MEDI4736, an anti-PD-L1 antibody, in patients with head and neck cancer
-
Fury M, Ou SI, Balmanoukian AS, et al: Clinical activity and safety of MEDI4736, an anti-PD-L1 antibody, in patients with head and neck cancer. Ann Oncol 25: S340-S356, 2014 (suppl 4)
-
(2014)
Ann Oncol
, vol.25
, pp. S340-S356
-
-
Fury, M.1
Ou, S.I.2
Balmanoukian, A.S.3
-
79
-
-
84944214918
-
Phase Ib trial of TLR8 agonist VTX-2237 in combination with cetuximab in patients with recurrent or metastatic squamous cell carcinomas of the head and neck (SCCHN
-
Presented at the Scottsdale, AZ, February 20-22
-
Chow LQM, Eaton KD, Baik C, et al: Phase Ib trial of TLR8 agonist VTX-2237 in combination with cetuximab in patients with recurrent or metastatic squamous cell carcinomas of the head and neck (SCCHN). Presented at the Multidisciplinary Head and Neck Cancer Symposium, Scottsdale, AZ, February 20-22, 2014
-
(2014)
Multidisciplinary Head and Neck Cancer Symposium
-
-
Chow, L.Q.M.1
Eaton, K.D.2
Baik, C.3
|