Pemetrexed in combination with cisplatin versus cisplatin monotherapy in patients with recurrent or metastatic head and neck cancer: Final results of a randomized, double-blind, placebo-controlled, phase 3 study

Cancer

Volumn 118, Issue 19, 2012, Pages 4694-4705

  Urba, Susan ^a   Van Herpen, Carla M L ^b   Sahoo, Tarini Prasad ^c   Shin, Dong M ^d   Licitra, Lisa ^e   Mezei, Klara ^f   Reuter, Christoph ^g   Hitt, Ricardo ^h   Russo, Francesca ⁱ   Chang, Shao Chun ⁱ   Hossain, Anwar M ⁱ   Frimodt Moller, Bente ⁱ   Koustenis, Andrew ⁱ   Hong, Ruey Long ^j  

^a UNIVERSITY OF MICHIGAN   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Jawaharlal Nehru Cancer Hospital & Research Centre Bhopal   (India)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NATIONAL CANCER INSTITUTE   (Italy)

^f Onkoradiologiai Osztaly Szent Istvan   (Hungary)

^g HANNOVER MEDICAL SCHOOL   (Germany)

^h HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

ⁱ ELI LILLY AND COMPANY   (United States)

^j NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

more..

Author keywords

cisplatin; clinical trial; head and neck cancer; pemetrexed; phase 3

Indexed keywords

ANALGESIC AGENT; ANTIINFECTIVE AGENT; CISPLATIN; ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; PEMETREXED; PLACEBO;

ADULT; AGED; ANEMIA; ANOREXIA; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER PATIENT; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FATIGUE; FEBRILE NEUTROPENIA; FEMALE; HAZARD RATIO; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; INTENTION TO TREAT ANALYSIS; KARNOFSKY PERFORMANCE STATUS; KIDNEY FAILURE; LEUKOPENIA; MAJOR CLINICAL STUDY; MALE; METASTASIS; MONOTHERAPY; MULTIPLE CYCLE TREATMENT; NAUSEA; NEUTROPENIA; OROPHARYNX CANCER; OVERALL SURVIVAL; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RANDOMIZED CONTROLLED TRIAL; RECURRENT CANCER; THROMBOCYTOPENIA; VOMITING;

ADULT; AGED; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CISPLATIN; DOUBLE-BLIND METHOD; FEMALE; GLUTAMATES; GUANINE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; TREATMENT OUTCOME;

EID: 84866524667     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.27449     Document Type: Article

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