Human papillomavirus and overall survival after progression of oropharyngeal squamous cell carcinoma

Journal of Clinical Oncology

Volumn 32, Issue 30, 2014, Pages 3365-3373

  Fakhry, Carole ^a   Zhang, Qiang ^b   Nguyen Tan, Phuc Felix ⁱ   Rosenthal, David ^d   El Naggar, Adel ^d   Garden, Adam S ^d   Soulieres, Denis ⁱ   Trotti, Andy ^e   Avizonis, Vilija ^f   Ridge, John Andrew ^c   Harris, Jonathan ^b   Le, Quynh Thu ^g   Gillison, Maura ^h  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b Radiation Therapy Oncology Group Statistical Center   (United States)

^c FOX CHASE CANCER CENTER   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^f INTERMOUNTAIN MEDICAL CENTER   (United States)

^g STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^h THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

ⁱ NOTRE DAME HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CETUXIMAB; CISPLATIN; PLATINUM; PROTEIN P16; P16 PROTEIN, HUMAN; TUMOR PROTEIN;

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CAUSE OF DEATH; CHEMORADIOTHERAPY; DISEASE ASSOCIATION; DISEASE COURSE; DISTANT METASTASIS; DRUG MEGADOSE; FEMALE; FOLLOW UP; HIGH RISK POPULATION; HUMAN; INTENSITY MODULATED RADIATION THERAPY; INTERMEDIATE RISK POPULATION; LOW RISK POPULATION; LUNG METASTASIS; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; OROPHARYNX CARCINOMA; OVERALL SURVIVAL; PATIENT COUNSELING; PHASE 3 CLINICAL TRIAL; PROGRESSION FREE SURVIVAL; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; RISK FACTOR; RISK REDUCTION; SALVAGE THERAPY; SMOKING; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; TREATMENT OUTCOME; WART VIRUS; AGED; CONTROLLED STUDY; ISOLATION AND PURIFICATION; MIDDLE AGED; MORTALITY; OROPHARYNX TUMOR; PAPILLOMA VIRUS; PROPORTIONAL HAZARDS MODEL; RANDOMIZED CONTROLLED TRIAL; VIROLOGY;

ADULT; AGED; CARCINOMA, SQUAMOUS CELL; DISEASE PROGRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; OROPHARYNGEAL NEOPLASMS; PAPILLOMAVIRIDAE; PROPORTIONAL HAZARDS MODELS;

EID: 84908311901     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2014.55.1937     Document Type: Article

References (33)

1. Ang KK, Harris J, Wheeler R, et al: Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 363:24-35, 2010
2. Fakhry C, Gillison ML: Clinical implications of human papillomavirus in head and neck cancers. J Clin Oncol 24:2606-2611, 2006
3. Fakhry C, Westra WH, Li S, et al: Improved survival of patients with human papillomaviruspositive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst 100: 261-269, 2008
4. Huang SH, Perez-Ordonez B, Weinreb I, et al: Natural course of distant metastases following radiotherapy or chemoradiotherapy in HPV-related oropharyngeal cancer. Oral Oncol 49:79-85, 2013
5. Weinberger PM, Yu Z, Haffty BG, et al: Molecular classification identifies a subset of human papillomavirus-associated oropharyngeal cancers with favorable prognosis. J Clin Oncol 24:736-747, 2006
6. O'Sullivan B, Huang SH, Siu LL, et al: Deintensification candidate subgroups in human papillomavirusrelated oropharyngeal cancer according to minimal risk of distant metastasis. J Clin Oncol 31:543-550, 2013
7. Lin BM, Wang H, D'Souza G, et al: Long-term prognosis and risk factors among patients with HPV-associated oropharyngeal squamous cell carcinoma. Cancer 119:3462-3471, 2013
8. Bulut OC, Lindel K, Hauswald H, et al: Clinical and molecular characteristics of HNSCC patients with brain metastases: A retrospective study. Eur Arch Otorhinolaryngol 271:1715-1722, 2014
9. Ruzevick J, Olivi A, Westra WH: Metastatic squamous cell carcinoma to the brain: An unrecognized pattern of distant spread in patients with HPV-related head and neck cancer. J Neurooncol 112:449-454, 2013
10. Mü ller S, Khuri FR, Kono SA, et al: HPV positive squamous cell carcinoma of the oropharynx: Are we observing an unusual pattern of metastases? Head Neck Pathol 6:336-344, 2012
11. Huang SH, Perez-Ordonez B, Liu FF, et al: Atypical clinical behavior of p16-confirmed HPVrelated oropharyngeal squamous cell carcinoma treated with radical radiotherapy. Int J Radiat Oncol Biol Phys 82:276-283, 2012
12. Chaturvedi AK, Engels EA, Pfeiffer RM, et al: Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol 29:4294-4301, 2011
13. Ang KK, Zhang QE, Rosenthal DI, et al: A randomized phase III trial (RTOG 0522) of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III-IV head and neck squamous cell carcinomas (HNC). J Clin Oncol 29: 360s, 2011 (suppl; abstr 5500)
14. RTOG 0522: A randomized phase III trial of concurrent accelerated radiation and cisplatin versus concurrent accelerated radiation, cisplatin, and cetuximab [followed by surgery for selected patients] for Stage III and IV head and neck carcinomas. Clin Adv Hematol Oncol 5:79-81, 2007
15. Flaming I, Cooper J, Henson D, et al: AJCC Cancer Staging Manual (ed 5). Philadephia, PA, Lippincott-Raven, 1997
16. Bonner JA, Harari PM, Giralt J, et al: Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 354: 567-578, 2006
17. Begum S, Gillison ML, Ansari-Lari MA, et al: Detection of human papillomavirus in cervical lymph nodes: A highly efffective strategy for localizing site of tumor origin. Clin Cancer Res 9:6469-6475, 2003
18. Jordan RC, Lingen MW, Perez-Ordonez B, et al: Validation of methods for oropharyngeal cancer HPV status determination in US cooperative group trials. Am J Surg Pathol 36:945-954, 2012
19. Grønhoj Larsen C, Gyldenløve M, Jensen DH, et al: Correlation between human papillomavirus and p16 overexpression in oropharyngeal tumours: A systematic review. Br J Cancer 110:1587-1594, 2014
20. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
21. Mantel N: Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep 5:163-170, 1966
22. Cox D: Regression models and life tables. J Royal Statist Soc 34:187-229, 1972
23. Rubin D: Multiple Imputation for Nonresponse in Surveys. New York, NY, John Wiley & Sons, 1987
24. Vermorken JB, Stö hlmacher-Williams J, Davidenko I, et al: Cisplatin and fluorouracil with or without panitumumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (SPECTRUM): An open-label phase 3 randomised trial. Lancet Oncol 14:697-710, 2013
25. Argiris A, Li S, Ghebremichael M, et al: Prognostic signficance of human papillomavirus in recurrent or metastatic head and neck squamous cell cancer: An analysis of Eastern Cooperative Group trials. Ann Oncol [epub ahead of print on May 5, 2014]
26. Kimple RJ, Smith MA, Blitzer GC, et al: Enhanced radiation sensitivity in HPV-positive head and neck cancer. Cancer Res 73:4791-4800, 2013
27. Hafkamp HC, Mooren JJ, Claessen SM, et al: P21 Cip1/WAF1 expression is strongly associated with HPV-positive tonsillar carcinoma and a favorable prognosis. Mod Pathol 22:686-698, 2009
28. Kong CS, Narasimhan B, Cao H, et al: The relationship between human papillomavirus status and other molecular prognostic markers in head and neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys 74:553-561, 2009
29. Young RJ, Rischin D, Fisher R, et al: Relationship between epidermal growth factor receptor status, p16(INK4A), and outcome in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 20:1230-1237, 2011
30. Zafereo ME, Hanasono MM, Rosenthal DI, et al: The role of salvage surgery in patients with recurrent squamous cell carcinoma of the oropharynx. Cancer 115:5723-5733, 2009
31. Kano S, Homma A, Hayashi R, et al: Salvage surgery for recurrent oropharyngeal cancer after chemoradiotherapy. Int J Clin Oncol 18:817-823, 2013
32. Michiels S, Le Maître A, Buyse M, et al: Surrogate endpoints for overall survival in locally advanced head and neck cancer: Meta-analyses of individual patient data. Lancet Oncol 10:341-350, 2009
33. Bishop JA, Ogawa T, Chang X, et al: HPV analysis in distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma. Am J Surg Pathol 36:142-148, 2012