-
1
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger J: Cell signaling by receptor tyrosine kinases. Cell 103: 211-225, 2000.
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
2
-
-
0037429737
-
Epidermal growth factor receptor: Mechanisms of activation and signalling
-
DOI 10.1016/S0014-4827(02)00098-8
-
Jorissen RN, Walker F, Pouliot N, Garrett TP, Ward CW and Burgess AW: Epidermal growth factor receptor: mechanisms of activation and signalling. Exp Cell Res 284: 31-53, 2003. (Pubitemid 36331965)
-
(2003)
Experimental Cell Research
, vol.284
, Issue.1
, pp. 31-53
-
-
Jorissen, R.N.1
Walker, F.2
Pouliot, N.3
Garrett, T.P.J.4
Ward, C.W.5
Burgess, A.W.6
-
3
-
-
0026645077
-
Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: A Southwest Oncology Group study
-
Forastiere AA, Metch B, Schuller DE, Ensley JF, Hutchins LF, Triozzi P, Kish JA, McClure S, VonFeldt E and Williamson SK: Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamous-cell carcinoma of the head and neck: a Southwest Oncology Group study. J Clin Oncol 10: 1245-1251, 1992.
-
(1992)
J Clin Oncol
, vol.10
, pp. 1245-1251
-
-
Forastiere, A.A.1
Metch, B.2
Schuller, D.E.3
Ensley, J.F.4
Hutchins, L.F.5
Triozzi, P.6
Kish, J.A.7
McClure, S.8
VonFeldt, E.9
Williamson, S.K.10
-
4
-
-
20644452264
-
Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E 1395): An intergroup trial of the Eastern Cooperative Oncology Group
-
Gibson MK, Li Y, Murphy B, Hussain MH, DeConti RC, Ensley J and Forastiere AA: Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E 1395): an intergroup trial of the Eastern Cooperative Oncology Group. J Clin Oncol 23: 3562-3567, 2005.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3562-3567
-
-
Gibson, M.K.1
Li, Y.2
Murphy, B.3
Hussain, M.H.4
DeConti, R.C.5
Ensley, J.6
Forastiere, A.A.7
-
5
-
-
73249143536
-
Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
-
Bonner JA, Harari PM, Giralt J, Cohen RB, Jones CU, Sur RK, Raben D, Baselga J, Spencer SA, Zhu J, Youssoufian H, Rowinsky EK and Ang KK: Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival. Lancet Oncol 11: 21-28, 2010.
-
(2010)
Lancet Oncol
, vol.11
, pp. 21-28
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
Cohen, R.B.4
Jones, C.U.5
Sur, R.K.6
Raben, D.7
Baselga, J.8
Spencer, S.A.9
Zhu, J.10
Youssoufian, H.11
Rowinsky, E.K.12
Ang, K.K.13
-
6
-
-
51649085865
-
Platinumbased chemotherapy plus cetuximab in head and neck cancer
-
Vermorken JB, Mesia R, Rivera F, Remenar E, Kawecki A, Rottey S, Erfan J, Zabolotnyy D, Kienzer HR, Cupissol D, Peyrade F, Benasso M, Vynnychenko I, De Raucourt D, Bokemeyer C, Schueler A, Amellal N and Hitt R: Platinumbased chemotherapy plus cetuximab in head and neck cancer. N Engl J Med 359: 1116-1127, 2008.
-
(2008)
N Engl J Med
, vol.359
, pp. 1116-1127
-
-
Vermorken, J.B.1
Mesia, R.2
Rivera, F.3
Remenar, E.4
Kawecki, A.5
Rottey, S.6
Erfan, J.7
Zabolotnyy, D.8
Kienzer, H.R.9
Cupissol, D.10
Peyrade, F.11
Benasso, M.12
Vynnychenko, I.13
De Raucourt, D.14
Bokemeyer, C.15
Schueler, A.16
Amellal, N.17
Hitt, R.18
-
7
-
-
0037339858
-
Interethnic difference in the allelic distribution of human epidermal growth factor receptor intron 1 polymorphism
-
Liu W, Innocenti F, Chen P, Das S, Cook EH Jr and Ratain MJ: Interethnic difference in the allelic distribution of human epidermal growth factor receptor intron 1 polymorphism. Clin Cancer Res 9: 1009-1012, 2003. (Pubitemid 36323704)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.3
, pp. 1009-1012
-
-
Liu, W.1
Innocenti, F.2
Chen, P.3
Das, S.4
Cook Jr., E.H.5
Ratain, M.J.6
-
8
-
-
11244319884
-
A functional common polymorphism in a Sp1 recognition site of the epidermal growth factor receptor gene promoter
-
Liu W, Innocenti F, Wu MH, Desai AA, Dolan ME, Cook EH Jr and Ratain MJ: A functional common polymorphism in a Sp1 recognition site of the epidermal growth factor receptor gene promoter. Cancer Res 65: 46-53, 2005. (Pubitemid 40070794)
-
(2005)
Cancer Research
, vol.65
, Issue.1
, pp. 46-53
-
-
Liu, W.1
Innocenti, F.2
Wu, M.H.3
Desai, A.A.4
Dolan, M.E.5
Cook Jr., E.H.6
Ratain, M.J.7
-
9
-
-
36749088960
-
Relationship of EGFR mutations, expression, amplification, and polymorphisms to epidermal growth factor receptor inhibitors in the NCI60 cell lines
-
DOI 10.1158/1078-0432.CCR-07-0547
-
Liu W, Wu X, Zhang W, Montenegro RC, Fackenthal DL, Spitz JA, Huff LM, Innocenti F, Das S, Cook EH Jr, Cox NJ, Bates SE and Ratain MJ: Relationship of EGFR mutations, expression, amplification, and polymorphisms to epidermal growth factor receptor inhibitors in the NCI60 cell lines. Clin Cancer Res 13: 6788-6795, 2007. (Pubitemid 350206817)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.22
, pp. 6788-6795
-
-
Liu, W.1
Wu, X.2
Zhang, W.3
Montenegro, R.C.4
Fackenthal, D.L.5
Spitz, J.A.6
Huff, L.7
Innocenti, F.8
Das, S.9
Cook Jr., E.H.10
Cox, N.11
Bates, S.E.12
Ratain, M.J.13
-
10
-
-
33846252746
-
Mechanisms of egfr gene transcription modulation: Relationship to cancer risk and therapy response
-
DOI 10.1158/1078-0432.CCR-06-0626
-
Brandt B, Meyer-Staeckling S, Schmidt H, Agelopoulos K and Buerger H: Mechanisms of egfr gene transcription modulation: relationship to cancer risk and therapy response. Clin Cancer Res 12: 7252-7260, 2006. (Pubitemid 46095396)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.24
, pp. 7252-7260
-
-
Brandt, B.1
Meyer-Staeckling, S.2
Schmidt, H.3
Agelopoulos, K.4
Buerger, H.5
-
11
-
-
0028043510
-
A variant epidermal growth factor receptor exhibits altered type alpha transforming growth factor binding and transmembrane signaling
-
DOI 10.1073/pnas.91.21.10217
-
Moriai T, Kobrin MS, Hope C, Speck L and Korc M: A variant epidermal growth factor receptor exhibits altered type alpha transforming growth factor binding and transmembrane signaling. Proc Natl Acad Sci USA 91: 10217-10221, 1994. (Pubitemid 24311980)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.21
, pp. 10217-10221
-
-
Moriai, T.1
Kobrin, M.S.2
Hope, C.3
Speck, L.4
Korc, M.5
-
12
-
-
74949098030
-
Association of epidermal growth factor receptor polymorphism, skin toxicity, and outcome in patients with squamous cell carcinoma of the head and neck receiving cetuximab-docetaxel treatment
-
Klinghammer K, Knödler M, Schmittel A, Budach V, Keilholz U and Tinhofer I: Association of epidermal growth factor receptor polymorphism, skin toxicity, and outcome in patients with squamous cell carcinoma of the head and neck receiving cetuximab-docetaxel treatment. Clin Cancer Res 16: 304-310, 2010.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 304-310
-
-
Klinghammer, K.1
Knödler, M.2
Schmittel, A.3
Budach, V.4
Keilholz, U.5
Tinhofer, I.6
-
13
-
-
17444403242
-
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
-
DOI 10.1016/j.ccr.2005.03.003
-
Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P and Ferguson KM: Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell 7: 301-311, 2005. (Pubitemid 40544648)
-
(2005)
Cancer Cell
, vol.7
, Issue.4
, pp. 301-311
-
-
Li, S.1
Schmitz, K.R.2
Jeffrey, P.D.3
Wiltzius, J.J.W.4
Kussie, P.5
Ferguson, K.M.6
-
14
-
-
79851502880
-
EGFR codon 497 polymorphism - Implications for receptor sensitivity to inhibitors in HNSCC cell lines
-
Krohn V, Wiegand S, Werner JA and Mandic R: EGFR codon 497 polymorphism - implications for receptor sensitivity to inhibitors in HNSCC cell lines. Anticancer Res 31: 59-65, 2011.
-
(2011)
Anticancer Res
, vol.31
, pp. 59-65
-
-
Krohn, V.1
Wiegand, S.2
Werner, J.A.3
Mandic, R.4
-
15
-
-
78649744892
-
Prognostic vs predictive molecular biomarkers in colorectal cancer: Is KRAS and BRAF wild-type status required for antiEGFR therapy?
-
Rizzo S, Bronte G, Fanale D, Corsini L, Silvestris N, Santini D, Gulotta G, Bazan V, Gebbia N, Fulfaro F and Russo A: Prognostic vs predictive molecular biomarkers in colorectal cancer: is KRAS and BRAF wild-type status required for antiEGFR therapy? Cancer Treat Rev 36(Suppl 3): 56-61, 2010.
-
(2010)
Cancer Treat Rev
, vol.36
, Issue.SUPPL. 3
, pp. 56-61
-
-
Rizzo, S.1
Bronte, G.2
Fanale, D.3
Corsini, L.4
Silvestris, N.5
Santini, D.6
Gulotta, G.7
Bazan, V.8
Gebbia, N.9
Fulfaro, F.10
Russo, A.11
-
16
-
-
84856868920
-
EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small cell lung cancer (NSCLC): Analyses of data form the phase 3 FLEX study
-
doi 10 1016/S1470-2945(11)70318-7
-
Pirker R, Paz Ares L, Eberhardt W, Krzakowski M, Störkel S, Heeger S, von Heydebreck A, Stroh C and O'Byrne KJ: EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small cell lung cancer (NSCLC): analyses of data form the phase 3 FLEX study. Lancet doi 10 1016/S1470-2945(11)70318-7, 2011.
-
(2011)
Lancet
-
-
Pirker, R.1
Paz Ares, L.2
Eberhardt, W.3
Krzakowski, M.4
Störkel, S.5
Heeger, S.6
Von Heydebreck, A.7
Stroh, C.8
O'Byrne, K.J.9
-
17
-
-
78649469283
-
Epidermal growth factor receptor targeted therapy of squamous cell carcinoma of the head and neck
-
Sharafinski ME, Ferris RL, Ferrone S and Grandis JR: Epidermal growth factor receptor targeted therapy of squamous cell carcinoma of the head and neck. Head Neck 32: 1412-1421, 2010.
-
(2010)
Head Neck
, vol.32
, pp. 1412-1421
-
-
Sharafinski, M.E.1
Ferris, R.L.2
Ferrone, S.3
Grandis, J.R.4
-
18
-
-
77958109558
-
Mutational analyses of the BRAF, KRAS, and PIK3CA genes in oral squamous cell carcinoma
-
Bruckman KC, Schönleben F, Qiu W, Woo VL and Su GH: Mutational analyses of the BRAF, KRAS, and PIK3CA genes in oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 110: 632-637, 2010.
-
(2010)
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
, vol.110
, pp. 632-637
-
-
Bruckman, K.C.1
Schönleben, F.2
Qiu, W.3
Woo, V.L.4
Su, G.H.5
-
19
-
-
79961000118
-
Expression of amphiregulin and EGFRvIII affect outcome of patients with squamous cell carcinoma of the head and neck receiving cetuximab-docetaxel treatment
-
Tinhofer I, Klinghammer K, Weichert W, Knödler M, Stenzinger A, Gauler T, Budach V and Keilholz U: Expression of amphiregulin and EGFRvIII affect outcome of patients with squamous cell carcinoma of the head and neck receiving cetuximab-docetaxel treatment. Clin Cancer Res 17(15): 5197-5204, 2011.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.15
, pp. 5197-5204
-
-
Tinhofer, I.1
Klinghammer, K.2
Weichert, W.3
Knödler, M.4
Stenzinger, A.5
Gauler, T.6
Budach, V.7
Keilholz, U.8
-
20
-
-
69049115069
-
Role of polymorphic Fc gamma receptor IHa and EGFR expression level in cetuximab mediated, NK cell dependent in vitro cytotoxicity of head and neck squamous cell carcinoma cells
-
López-Albaitero A, Lee SC, Morgan S, Grandis JR, Gooding WE, Ferrone S and Ferris RL: Role of polymorphic Fc gamma receptor IHa and EGFR expression level in cetuximab mediated, NK cell dependent in vitro cytotoxicity of head and neck squamous cell carcinoma cells. Cancer Immunol Immunother 58: 1853-1864, 2009.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 1853-1864
-
-
López-Albaitero, A.1
Lee, S.C.2
Morgan, S.3
Grandis, J.R.4
Gooding, W.E.5
Ferrone, S.6
Ferris, R.L.7
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