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Volumn 5, Issue , 2015, Pages

Sensitive Determination of Onco-metabolites of D-and L-2-hydroxyglutarate Enantiomers by Chiral Derivatization Combined with Liquid Chromatography/Mass Spectrometry Analysis

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA-HYDROXYGLUTARATE; GLUTARIC ACID DERIVATIVE;

EID: 84944097106     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep15217     Document Type: Article
Times cited : (57)

References (37)
  • 1
    • 80053922625 scopus 로고    scopus 로고
    • Metabolic flux and the regulation of mammalian cell growth
    • Locasale, J. W., Cantley, L. C. Metabolic flux and the regulation of mammalian cell growth. Cell Metab 14, 443-451 (2011).
    • (2011) Cell Metab , vol.14 , pp. 443-451
    • Locasale, J.W.1    Cantley, L.C.2
  • 2
    • 33749052511 scopus 로고    scopus 로고
    • Rheostat control of gene expression by metabolites
    • Ladurner, A. G. Rheostat control of gene expression by metabolites. Mol Cell 24, 1-11 (2006).
    • (2006) Mol Cell , vol.24 , pp. 1-11
    • Ladurner, A.G.1
  • 3
    • 33744969828 scopus 로고    scopus 로고
    • Energy deregulation: Licensing tumors to grow
    • Garber, K. Energy deregulation: licensing tumors to grow. Science 312, 1158-1159 (2006).
    • (2006) Science , vol.312 , pp. 1158-1159
    • Garber, K.1
  • 4
    • 84877620952 scopus 로고    scopus 로고
    • Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation
    • Wang, F. et al. Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science 340, 622-626 (2013).
    • (2013) Science , vol.340 , pp. 622-626
    • Wang, F.1
  • 5
    • 84888642138 scopus 로고    scopus 로고
    • Metabolism: IDH2 drives cancer in vivo
    • Lokody, I. Metabolism: IDH2 drives cancer in vivo. Nat Rev Cancer 13, 756-757 (2013).
    • (2013) Nat Rev Cancer , vol.13 , pp. 756-757
    • Lokody, I.1
  • 6
    • 72049125350 scopus 로고    scopus 로고
    • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
    • Dang, L. et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 462, 739-744 (2009).
    • (2009) Nature , vol.462 , pp. 739-744
    • Dang, L.1
  • 7
    • 77649305610 scopus 로고    scopus 로고
    • The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
    • Ward, P. S. et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell 17, 225-234 (2010).
    • (2010) Cancer Cell , vol.17 , pp. 225-234
    • Ward, P.S.1
  • 8
    • 78650864017 scopus 로고    scopus 로고
    • Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases
    • Loenarz, C., Schofield, C. J. Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases. Trends Biochem Sci 36, 7-18 (2011).
    • (2011) Trends Biochem Sci , vol.36 , pp. 7-18
    • Loenarz, C.1    Schofield, C.J.2
  • 9
    • 84890831574 scopus 로고    scopus 로고
    • 2-Hydroxyglutarate is not a metabolite; D-2-hydroxyglutarate and L-2-hydroxyglutarate are
    • Struys, E. A. 2-Hydroxyglutarate is not a metabolite; D-2-hydroxyglutarate and L-2-hydroxyglutarate are! Proc Natl Acad Sci USA 110, E4939 (2013).
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. E4939
    • Struys, E.A.1
  • 10
    • 72049125350 scopus 로고    scopus 로고
    • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
    • Dang, L. et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 462, 739-U752 (2009).
    • (2009) Nature , vol.462 , pp. 739-U752
    • Dang, L.1
  • 11
    • 84885759123 scopus 로고    scopus 로고
    • Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China
    • Wang, J. H. et al. Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China. Proc Natl Acad Sci USA 110, 17017-17022 (2013).
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 17017-17022
    • Wang, J.H.1
  • 12
    • 84907033777 scopus 로고    scopus 로고
    • Mutant IDH inhibits HNF-4alpha to block hepatocyte differentiation and promote biliary cancer
    • Saha, S. K. et al. Mutant IDH inhibits HNF-4alpha to block hepatocyte differentiation and promote biliary cancer. Nature 513, 110-114 (2014).
    • (2014) Nature , vol.513 , pp. 110-114
    • Saha, S.K.1
  • 13
    • 77149134353 scopus 로고    scopus 로고
    • Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
    • Gross, S. et al. Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations. J Exp Med 207, 339-344 (2010).
    • (2010) J Exp Med , vol.207 , pp. 339-344
    • Gross, S.1
  • 14
    • 77958534745 scopus 로고    scopus 로고
    • Increased levels of 2-hydroxyglutarate in AML patients with IDH1-R132H and IDH2-R140Q mutations
    • Sellner, L. et al. Increased levels of 2-hydroxyglutarate in AML patients with IDH1-R132H and IDH2-R140Q mutations. Eur J Haematol 85, 457-459 (2010).
    • (2010) Eur J Haematol , vol.85 , pp. 457-459
    • Sellner, L.1
  • 15
    • 84895821588 scopus 로고    scopus 로고
    • Serum 2-hydroxyglutarate production in IDH1-and IDH2-mutated de novo acute myeloid leukemia: A study by the Acute Leukemia French Association group
    • Janin, M. et al. Serum 2-hydroxyglutarate production in IDH1-and IDH2-mutated de novo acute myeloid leukemia: a study by the Acute Leukemia French Association group. J Clin Oncol 32, 297-305 (2014).
    • (2014) J Clin Oncol , vol.32 , pp. 297-305
    • Janin, M.1
  • 16
    • 16844378167 scopus 로고    scopus 로고
    • L-2-hydroxyglutaric aciduria: Clinical, neuroimaging, and neuropathological findings
    • Seijo-Martinez, M. et al. L-2-hydroxyglutaric aciduria: clinical, neuroimaging, and neuropathological findings. Arch Neurol 62, 666-670 (2005).
    • (2005) Arch Neurol , vol.62 , pp. 666-670
    • Seijo-Martinez, M.1
  • 17
    • 77149173436 scopus 로고    scopus 로고
    • Evidence for genetic heterogeneity in d-2-hydroxyglutaric aciduria
    • Kranendijk, M. et al. Evidence for Genetic Heterogeneity in D-2-Hydroxyglutaric Aciduria. Human Mutation 31, 279-283 (2010).
    • (2010) Human Mutation , vol.31 , pp. 279-283
    • Kranendijk, M.1
  • 18
    • 0033884063 scopus 로고    scopus 로고
    • Chiral liquid chromatography tandem mass spectrometry in the determination of the configuration of 2-hydroxyglutaric acid in urine
    • Rashed, M. S., AlAmoudi, M., Aboul-Enein, H. Y. Chiral liquid chromatography tandem mass spectrometry in the determination of the configuration of 2-hydroxyglutaric acid in urine. Biomed Chromatogr 14, 317-320 (2000).
    • (2000) Biomed Chromatogr , vol.14 , pp. 317-320
    • Rashed, M.S.1    AlAmoudi, M.2    Aboul-Enein, H.Y.3
  • 19
    • 0019152867 scopus 로고
    • D-2-hydroxyglutaric aciduria: Case report and biochemical studies
    • Chalmers, R. A. et al. D-2-hydroxyglutaric aciduria: case report and biochemical studies. J Inherit Metab Dis 3, 11-15 (1980).
    • (1980) J Inherit Metab Dis , vol.3 , pp. 11-15
    • Chalmers, R.A.1
  • 20
    • 67651001565 scopus 로고    scopus 로고
    • Enantioselective determination of trantinterol in rat plasma by ultra performance liquid chromatographyelectrospray ionization mass spectrometry after derivatization
    • Yang, J. et al. Enantioselective determination of trantinterol in rat plasma by ultra performance liquid chromatographyelectrospray ionization mass spectrometry after derivatization. Talanta 79, 1204-1208 (2009).
    • (2009) Talanta , vol.79 , pp. 1204-1208
    • Yang, J.1
  • 21
    • 84867403701 scopus 로고    scopus 로고
    • Determination of naftopidil enantiomers in rat plasma using chiral solid phases and pre-column derivatization high-performance liquid chromatography
    • Liu, X. W., Zhang, Y. Y., Yuan, M., Sun, Y. X. Determination of naftopidil enantiomers in rat plasma using chiral solid phases and pre-column derivatization high-performance liquid chromatography. J Chromatogr B 907, 140-145 (2012).
    • (2012) J Chromatogr B , vol.907 , pp. 140-145
    • Liu, X.W.1    Zhang, Y.Y.2    Yuan, M.3    Sun, Y.X.4
  • 22
    • 84859711290 scopus 로고    scopus 로고
    • L(+ ) and D(? ) lactate are increased in plasma and urine samples of type 2 diabetes as measured by a simultaneous quantification of L(+ ) and D(? ) lactate by reversed-phase liquid chromatography tandem mass spectrometry
    • Scheijen, J. L. et al. L(+ ) and D(? ) lactate are increased in plasma and urine samples of type 2 diabetes as measured by a simultaneous quantification of L(+ ) and D(? ) lactate by reversed-phase liquid chromatography tandem mass spectrometry. Exp Diabetes Res 2012, 234812 (2012).
    • (2012) Exp Diabetes Res , vol.2012 , pp. 234812
    • Scheijen, J.L.1
  • 23
    • 80053949917 scopus 로고    scopus 로고
    • Use of isotope differential derivatization for simultaneous determination of thiols and oxidized thiols by liquid chromatography tandem mass spectrometry
    • Huang, Y. Q., Ruan, G. D., Liu, J. Q., Gao, Q., Feng, Y. Q. Use of isotope differential derivatization for simultaneous determination of thiols and oxidized thiols by liquid chromatography tandem mass spectrometry. Anal Biochem 416, 159-166 (2011).
    • (2011) Anal Biochem , vol.416 , pp. 159-166
    • Huang, Y.Q.1    Ruan, G.D.2    Liu, J.Q.3    Gao, Q.4    Feng, Y.Q.5
  • 24
    • 84937509439 scopus 로고    scopus 로고
    • Metal oxide-based selective enrichment combined with stable isotope labeling-mass spectrometry analysis for profiling of ribose conjugates
    • Chu, J. M. et al. Metal Oxide-Based Selective Enrichment Combined with Stable Isotope Labeling-Mass Spectrometry Analysis for Profiling of Ribose Conjugates. Anal Chem 87, 7364-7372 (2015).
    • (2015) Anal Chem , vol.87 , pp. 7364-7372
    • Chu, J.M.1
  • 25
    • 84889040799 scopus 로고    scopus 로고
    • 5-Diethylamino-naphthalene-1-sulfonyl chloride (DensCl): A novel triplex isotope labeling reagent for quantitative metabolome analysis by liquid chromatography mass spectrometry
    • Zhou, R., Guo, K., Li, L. 5-Diethylamino-naphthalene-1-sulfonyl chloride (DensCl): a novel triplex isotope labeling reagent for quantitative metabolome analysis by liquid chromatography mass spectrometry. Anal Chem 85, 11532-11539 (2013).
    • (2013) Anal Chem , vol.85 , pp. 11532-11539
    • Zhou, R.1    Guo, K.2    Li, L.3
  • 26
    • 84887202472 scopus 로고    scopus 로고
    • Searching for urine biomarkers of bladder cancer recurrence using a liquid chromatography-mass spectrometry and capillary electrophoresis-mass spectrometry metabolomics approach
    • Alberice, J. V. et al. Searching for urine biomarkers of bladder cancer recurrence using a liquid chromatography-mass spectrometry and capillary electrophoresis-mass spectrometry metabolomics approach. J Chromatogr A 1318, 163-170 (2013).
    • (2013) J Chromatogr A , vol.1318 , pp. 163-170
    • Alberice, J.V.1
  • 27
    • 84902182150 scopus 로고    scopus 로고
    • Mechanism and function of oxidative reversal of DNA and RNA methylation
    • Shen, L., Song, C. X., He, C., Zhang, Y. Mechanism and function of oxidative reversal of DNA and RNA methylation. Annu Rev Biochem 83, 585-614 (2014).
    • (2014) Annu Rev Biochem , vol.83 , pp. 585-614
    • Shen, L.1    Song, C.X.2    He, C.3    Zhang, Y.4
  • 28
    • 84892657738 scopus 로고    scopus 로고
    • Recent advances in the analysis of 5-methylcytosine and its oxidation products
    • Yuan, B. F., Feng, Y. Q. Recent advances in the analysis of 5-methylcytosine and its oxidation products. TrAC-Trend Anal Chem 54, 24-35 (2014).
    • (2014) TrAC-Trend Anal Chem , vol.54 , pp. 24-35
    • Yuan, B.F.1    Feng, Y.Q.2
  • 29
    • 84921914405 scopus 로고    scopus 로고
    • 5-Methylcytosine and its derivatives
    • Yuan, B. F. 5-Methylcytosine and Its Derivatives. Adv Clin Chem 67, 151-187 (2014).
    • (2014) Adv Clin Chem , vol.67 , pp. 151-187
    • Yuan, B.F.1
  • 30
    • 84876944890 scopus 로고    scopus 로고
    • Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry
    • Chen, M. L. et al. Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry. Clin chem 59, 824-832 (2013).
    • (2013) Clin Chem , vol.59 , pp. 824-832
    • Chen, M.L.1
  • 31
    • 84924942223 scopus 로고    scopus 로고
    • Sensitive and simultaneous determination of 5-methylcytosine and its oxidation products in genomic DNA by chemical derivatization coupled with liquid chromatography-tandem mass spectrometry analysis
    • Tang, Y., Zheng, S. J., Qi, C. B., Feng, Y. Q., Yuan, B. F. Sensitive and simultaneous determination of 5-methylcytosine and its oxidation products in genomic DNA by chemical derivatization coupled with liquid chromatography-tandem mass spectrometry analysis. Anal Chem 87, 3445-3452 (2015).
    • (2015) Anal Chem , vol.87 , pp. 3445-3452
    • Tang, Y.1    Zheng, S.J.2    Qi, C.B.3    Feng, Y.Q.4    Yuan, B.F.5
  • 32
    • 84255200412 scopus 로고    scopus 로고
    • 5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations
    • Jin, S. G. et al. 5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. Cancer Res 71, 7360-7365 (2011).
    • (2011) Cancer Res , vol.71 , pp. 7360-7365
    • Jin, S.G.1
  • 33
    • 84856058152 scopus 로고    scopus 로고
    • Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers
    • Haffner, M. C. et al. Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Oncotarget 2, 627-637 (2011).
    • (2011) Oncotarget , vol.2 , pp. 627-637
    • Haffner, M.C.1
  • 34
    • 84921487369 scopus 로고    scopus 로고
    • Determination of hexanal and heptanal in human urine using magnetic solid phase extraction coupled with in-situ derivatization by high performance liquid chromatography
    • Liu, J. F., Yuan, B. F., Feng, Y. Q. Determination of hexanal and heptanal in human urine using magnetic solid phase extraction coupled with in-situ derivatization by high performance liquid chromatography. Talanta 136, 54-59 (2015).
    • (2015) Talanta , vol.136 , pp. 54-59
    • Liu, J.F.1    Yuan, B.F.2    Feng, Y.Q.3
  • 35
    • 84922879638 scopus 로고    scopus 로고
    • Profiling of cis-diol-containing nucleosides and ribosylated metabolites by boronate-affinity organic-silica hybrid monolithic capillary liquid chromatography/mass spectrometry
    • Jiang, H. P., Qi, C. B., Chu, J. M., Yuan, B. F., Feng, Y. Q. Profiling of cis-Diol-containing Nucleosides and Ribosylated Metabolites by Boronate-affinity Organic-silica Hybrid Monolithic Capillary Liquid Chromatography/Mass Spectrometry. Sci Rep 5, 7785 (2015).
    • (2015) Sci Rep , vol.5 , pp. 7785
    • Jiang, H.P.1    Qi, C.B.2    Chu, J.M.3    Yuan, B.F.4    Feng, Y.Q.5
  • 36
    • 84896821615 scopus 로고    scopus 로고
    • D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice
    • Akbay, E. A. et al. D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice. Genes Dev 28, 479-490 (2014).
    • (2014) Genes Dev , vol.28 , pp. 479-490
    • Akbay, E.A.1
  • 37
    • 37349091160 scopus 로고    scopus 로고
    • Column-based method to simultaneously extract DNA, RNA, and proteins from the same sample
    • Tolosa, J. M., Schjenken, J. E., Civiti, T. D., Clifton, V. L., Smith, R. Column-based method to simultaneously extract DNA, RNA, and proteins from the same sample. Biotechniques 43, 799-804 (2007).
    • (2007) Biotechniques , vol.43 , pp. 799-804
    • Tolosa, J.M.1    Schjenken, J.E.2    Civiti, T.D.3    Clifton, V.L.4    Smith, R.5


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