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Volumn 290, Issue 41, 2015, Pages 24986-25011

Genome-wide mechanosensitive microRNA (MechanomiR) screen uncovers dysregulation of their regulatory networks in the mdm mouse model of muscular dystrophy

Author keywords

[No Author keywords available]

Indexed keywords

DIAPHRAGMS; ENZYME ACTIVITY; GENE EXPRESSION; GENES; MAMMALS; MUSCLE; RNA;

EID: 84943773912     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.659375     Document Type: Article
Times cited : (22)

References (76)
  • 1
    • 0023614188 scopus 로고
    • Dystrophin: The protein product of the Duchenne muscular dystrophy locus
    • Hoffman, E. P., Brown, R. H., Jr., and Kunkel, L. M. (1987) Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell 51, 919-928
    • (1987) Cell , vol.51 , pp. 919-928
    • Hoffman, E.P.1    Brown, R.H.2    Kunkel, L.M.3
  • 2
    • 0023904860 scopus 로고
    • The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein
    • Koenig, M., Monaco, A. P., and Kunkel, L. M. (1988) The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein. Cell 53, 219-228
    • (1988) Cell , vol.53 , pp. 219-228
    • Koenig, M.1    Monaco, A.P.2    Kunkel, L.M.3
  • 4
    • 0037195860 scopus 로고    scopus 로고
    • Distinct signaling pathways are activated in response to mechanical stress applied axially and transversely to skeletal muscle fibers
    • Kumar, A., Chaudhry, I., Reid, M. B., and Boriek, A. M. (2002) Distinct signaling pathways are activated in response to mechanical stress applied axially and transversely to skeletal muscle fibers. J. Biol. Chem. 277, 46493-46503
    • (2002) J. Biol. Chem. , vol.277 , pp. 46493-46503
    • Kumar, A.1    Chaudhry, I.2    Reid, M.B.3    Boriek, A.M.4
  • 5
    • 0037336186 scopus 로고    scopus 로고
    • Mechanical stress activates the nuclear factor-κB pathway in skeletal muscle fibers: A possible role in Duchenne muscular dystrophy
    • Kumar, A., and Boriek, A. M. (2003) Mechanical stress activates the nuclear factor-κB pathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy. FASEBJ. 17, 386-396
    • (2003) FASEBJ. , vol.17 , pp. 386-396
    • Kumar, A.1    Boriek, A.M.2
  • 6
    • 5044220051 scopus 로고    scopus 로고
    • Cyclic mechanical strain inhibits skeletal myogenesis through activation of focal adhesion kinase, Rac-1 GTPase, and NF-κB transcription factor
    • Kumar, A., Murphy, R., Robinson, P., Wei, L., and Boriek, A. M. (2004) Cyclic mechanical strain inhibits skeletal myogenesis through activation of focal adhesion kinase, Rac-1 GTPase, and NF-κB transcription factor. FASEBJ. 18, 1524-1535
    • (2004) FASEBJ. , vol.18 , pp. 1524-1535
    • Kumar, A.1    Murphy, R.2    Robinson, P.3    Wei, L.4    Boriek, A.M.5
  • 7
    • 77956644634 scopus 로고    scopus 로고
    • Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch
    • Mohamed, J. S., Lopez, M. A., Cox, G. A., and Boriek, A. M. (2010) Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch. FASEBJ. 24, 3330-3340
    • (2010) FASEBJ. , vol.24 , pp. 3330-3340
    • Mohamed, J.S.1    Lopez, M.A.2    Cox, G.A.3    Boriek, A.M.4
  • 9
    • 33846781220 scopus 로고    scopus 로고
    • Consequences of disrupting the dystrophin-sarcoglycan complex in cardiac and skeletal myopathy
    • Heydemann, A., and McNally, E. M. (2007) Consequences of disrupting the dystrophin-sarcoglycan complex in cardiac and skeletal myopathy. Trends Cardiovasc. Med. 17, 55-59
    • (2007) Trends Cardiovasc. Med. , vol.17 , pp. 55-59
    • Heydemann, A.1    McNally, E.M.2
  • 10
    • 0347915657 scopus 로고    scopus 로고
    • Loss of dystrophin causes aberrant mechanotransduction in skeletal muscle fibers
    • Kumar, A., Khandelwal, N., Malya, R., Reid, M. B., and Boriek, A. M. (2004) Loss of dystrophin causes aberrant mechanotransduction in skeletal muscle fibers. FASEBJ. 18, 102-113
    • (2004) FASEBJ. , vol.18 , pp. 102-113
    • Kumar, A.1    Khandelwal, N.2    Malya, R.3    Reid, M.B.4    Boriek, A.M.5
  • 11
    • 39349116396 scopus 로고    scopus 로고
    • Direct observation of failing fibers in muscles of dystrophic mice provides mechanistic insight into muscular dystrophy
    • Claflin, D. R., and Brooks, S. V. (2008) Direct observation of failing fibers in muscles of dystrophic mice provides mechanistic insight into muscular dystrophy. Am. J. Physiol. Cell Physiol. 294, C651-C658
    • (2008) Am. J. Physiol. Cell Physiol. , vol.294 , pp. C651-C658
    • Claflin, D.R.1    Brooks, S.V.2
  • 13
    • 57349120208 scopus 로고    scopus 로고
    • Early mechanical dysfunction of the diaphragm in the muscular dystrophy with myositis (Ttnmdm) model
    • Lopez, M. A., Pardo, P. S., Cox, G. A., and Boriek, A. M. (2008) Early mechanical dysfunction of the diaphragm in the muscular dystrophy with myositis (Ttnmdm) model. Am. J. Physiol. Cell Physiol. 295, C1092-C1102
    • (2008) Am. J. Physiol. Cell Physiol. , vol.295 , pp. C1092-C1102
    • Lopez, M.A.1    Pardo, P.S.2    Cox, G.A.3    Boriek, A.M.4
  • 14
    • 84883202862 scopus 로고    scopus 로고
    • Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction. J
    • Mohamed, J. S., Lopez, M. A., Cox, G. A., and Boriek, A. M. (2013) Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction. J. Biol. Chem. 288, 24560-24568
    • (2013) Biol. Chem. , vol.288 , pp. 24560-24568
    • Mohamed, J.S.1    Lopez, M.A.2    Cox, G.A.3    Boriek, A.M.4
  • 18
    • 84904341854 scopus 로고    scopus 로고
    • Mega roles of microRNAs in regulation of skeletal muscle health and disease
    • Sharma, M., Juvvuna, P. K., Kukreti, H, and McFarlane, C. (2014) Mega roles of microRNAs in regulation of skeletal muscle health and disease. Front. Physiol. 5, 239
    • (2014) Front. Physiol. , vol.5 , pp. 239
    • Sharma, M.1    Juvvuna, P.K.2    Kukreti, H.3    McFarlane, C.4
  • 19
    • 84911208248 scopus 로고    scopus 로고
    • MicroRNAs differentially regulated in cardiac and skeletal muscle in health and disease: Potential drug targets?
    • Winbanks, C. E., Ooi, J. Y., Nguyen, S. S., McMullen, J. R., and Bernardo, B. C. (2014) MicroRNAs differentially regulated in cardiac and skeletal muscle in health and disease: potential drug targets? Clin. Exp. Pharmacol. Physiol. 41, 727-737
    • (2014) Clin. Exp. Pharmacol. Physiol , vol.41 , pp. 727-737
    • Winbanks, C.E.1    Ooi, J.Y.2    Nguyen, S.S.3    McMullen, J.R.4    Bernardo, B.C.5
  • 20
    • 84885346880 scopus 로고    scopus 로고
    • MicroRNAs in skeletal muscle and their regulation with exercise, ageing, and disease
    • Zacharewicz, E., Lamon, S., and Russell, A. P. (2013) MicroRNAs in skeletal muscle and their regulation with exercise, ageing, and disease. Front. Physiol. 4, 266
    • (2013) Front. Physiol. , vol.4 , pp. 266
    • Zacharewicz, E.1    Lamon, S.2    Russell, A.P.3
  • 22
    • 34547114014 scopus 로고    scopus 로고
    • MicroRNA-206 is overexpressed in the diaphragm but not the hindlimb muscle of mdx mouse
    • McCarthy, J. J., Esser, K. A., and Andrade, F. H. (2007) MicroRNA-206 is overexpressed in the diaphragm but not the hindlimb muscle of mdx mouse. Am. J. Physiol. Cell Physiol. 293, C451-C457
    • (2007) Am. J. Physiol. Cell Physiol. , vol.293 , pp. C451-C457
    • McCarthy, J.J.1    Esser, K.A.2    Andrade, F.H.3
  • 23
    • 77956539987 scopus 로고    scopus 로고
    • Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3/3
    • Mohamed, J. S., Lopez, M. A., and Boriek, A. M. (2010) Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3/3. J. Biol. Chem. 285, 29336-29347
    • (2010) J. Biol. Chem. , vol.285 , pp. 29336-29347
    • Mohamed, J.S.1    Lopez, M.A.2    Boriek, A.M.3
  • 24
    • 82655181357 scopus 로고    scopus 로고
    • MiR-365: A mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4
    • Guan, Y. J., Yang, X., Wei, L., and Chen, Q. (2011) MiR-365: a mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4. FASEBJ. 25, 4457-4466
    • (2011) FASEBJ. , vol.25 , pp. 4457-4466
    • Guan, Y.J.1    Yang, X.2    Wei, L.3    Chen, Q.4
  • 25
    • 84864742290 scopus 로고    scopus 로고
    • MiR-146a regulates mechanotransduction and pressure-induced inflammation in small airway epithelium
    • Huang, Y., Crawford, M., Higuita-Castro, N, Nana-Sinkam, P., and Ghadiali, S. N (2012) miR-146a regulates mechanotransduction and pressure-induced inflammation in small airway epithelium. FASEB J. 26, 3351-3364
    • (2012) FASEB J. , vol.26 , pp. 3351-3364
    • Huang, Y.1    Crawford, M.2    Higuita-Castro, N.3    Nana-Sinkam, P.4    Ghadiali, S.N.5
  • 27
    • 84914106428 scopus 로고    scopus 로고
    • Role of flowsensitive microRNAs in endothelial dysfunction and atherosclerosis: Mechanosensitive athero-miRs
    • Kumar, S., Kim, C. W., Simmons, R. D., and Jo, H. (2014) Role of flowsensitive microRNAs in endothelial dysfunction and atherosclerosis: mechanosensitive athero-miRs. Arterioscler. Thromb. Vasc. Biol. 34, 2206-2216
    • (2014) Arterioscler. Thromb. Vasc. Biol. , vol.34 , pp. 2206-2216
    • Kumar, S.1    Kim, C.W.2    Simmons, R.D.3    Jo, H.4
  • 29
    • 84863301940 scopus 로고    scopus 로고
    • Mechanical loading and TGF-β change the expression of multiple miRNAs in tendon fibroblasts
    • Mendias, C. L., Gumucio, J. P., and Lynch, E. B. (2012) Mechanical loading and TGF-β change the expression of multiple miRNAs in tendon fibroblasts. J. Appl. Physiol. 113, 56-62
    • (2012) J. Appl. Physiol. , vol.113 , pp. 56-62
    • Mendias, C.L.1    Gumucio, J.P.2    Lynch, E.B.3
  • 31
    • 84921449095 scopus 로고    scopus 로고
    • MicroRNA-21 Mediates stretch-induced osteogenic differentiation in human periodontal ligament stem cells
    • Wei, F., Liu, D., Feng, C, Zhang, F., Yang, S., Hu, Y., Ding, G., and Wang, S. (2015) microRNA-21 Mediates stretch-induced osteogenic differentiation in human periodontal ligament stem cells. Stem Cells Dev. 24, 312-319
    • (2015) Stem Cells Dev. , vol.24 , pp. 312-319
    • Wei, F.1    Liu, D.2    Feng, C.3    Zhang, F.4    Yang, S.5    Hu, Y.6    Ding, G.7    Wang, S.8
  • 32
    • 83355163388 scopus 로고    scopus 로고
    • Desmin regulates airway smooth muscle hypertrophy through early growth-responsive protein-1 and microRNA-26a
    • Mohamed, J. S., Hajira, A., Li, Z., Paulin, D., and Boriek, A. M. (2011) Desmin regulates airway smooth muscle hypertrophy through early growth-responsive protein-1 and microRNA-26a. J. Biol. Chem. 286, 43394-43404
    • (2011) J. Biol. Chem. , vol.286 , pp. 43394-43404
    • Mohamed, J.S.1    Hajira, A.2    Li, Z.3    Paulin, D.4    Boriek, A.M.5
  • 33
  • 34
    • 0035707910 scopus 로고    scopus 로고
    • The muscular dystrophy with myositis (mdm) mouse mutation disrupts a skeletal muscle-specific domain of titin
    • Garvey, S. M., Rajan, C., Lerner, A. P., Frankel, W. N., and Cox, G. A. (2002) The muscular dystrophy with myositis (mdm) mouse mutation disrupts a skeletal muscle-specific domain of titin. Genomics 79, 146-149
    • (2002) Genomics , vol.79 , pp. 146-149
    • Garvey, S.M.1    Rajan, C.2    Lerner, A.P.3    Frankel, W.N.4    Cox, G.A.5
  • 35
    • 0032479445 scopus 로고    scopus 로고
    • Functional defects of a musclespecific calpain, p94, caused by mutations associated with limb-girdle muscular dystrophy type 2A
    • Ono, Y., Shimada, H., Sorimachi, H., Richard, I., Saido, T. C., Beckmann, J. S., Ishiura, S., and Suzuki, K. (1998) Functional defects of a musclespecific calpain, p94, caused by mutations associated with limb-girdle muscular dystrophy type 2A. J. Biol. Chem. 273, 17073-17078
    • (1998) J. Biol. Chem. , vol.273 , pp. 17073-17078
    • Ono, Y.1    Shimada, H.2    Sorimachi, H.3    Richard, I.4    Saido, T.C.5    Beckmann, J.S.6    Ishiura, S.7    Suzuki, K.8
  • 37
    • 79959805164 scopus 로고    scopus 로고
    • MiRWalk-database: Prediction of possible miRNA binding sites by "walking" the genes of three genomes
    • Dweep, H., Sticht, C., Pandey, P., and Gretz, N. (2011) miRWalk-database: prediction of possible miRNA binding sites by "walking" the genes of three genomes. J. Biomed. Inform. 44, 839-847
    • (2011) J. Biomed. Inform. , vol.44 , pp. 839-847
    • Dweep, H.1    Sticht, C.2    Pandey, P.3    Gretz, N.4
  • 38
    • 84899103245 scopus 로고    scopus 로고
    • MicroRNA-149 inhibits PARP-2 and promotes mitochondrial biogenesis via SIRT-1/PGC-1α network in skeletal muscle
    • Mohamed, J. S., Hajira, A., Pardo, P. S., and Boriek, A. M. (2014) MicroRNA-149 inhibits PARP-2 and promotes mitochondrial biogenesis via SIRT-1/PGC-1α network in skeletal muscle. Diabetes 63, 1546-1559
    • (2014) Diabetes , vol.63 , pp. 1546-1559
    • Mohamed, J.S.1    Hajira, A.2    Pardo, P.S.3    Boriek, A.M.4
  • 39
    • 1642374097 scopus 로고    scopus 로고
    • Specificity of microRNA target selection in translational repression
    • Doench, J. G., and Sharp, P. A. (2004) Specificity of microRNA target selection in translational repression. Genes Dev. 18, 504-511
    • (2004) Genes Dev. , vol.18 , pp. 504-511
    • Doench, J.G.1    Sharp, P.A.2
  • 47
    • 78650501005 scopus 로고    scopus 로고
    • Prevention of muscle fibrosis and myonecrosis in mdx mice by suramin, a TGF-β1 blocker
    • Taniguti, A. P., Pertille, A., Matsumura, C. Y., Santo Neto, H., and Marques, M. J. (2011) Prevention of muscle fibrosis and myonecrosis in mdx mice by suramin, a TGF-β1 blocker. Muscle Nerve 43, 82-87
    • (2011) Muscle Nerve , vol.43 , pp. 82-87
    • Taniguti, A.P.1    Pertille, A.2    Matsumura, C.Y.3    Santo Neto, H.4    Marques, M.J.5
  • 50
    • 0035114996 scopus 로고    scopus 로고
    • Impact of prednisone on TGF-β1 and collagen in diaphragm muscle from mdx mice
    • Hartel, J. V., Granchelli, J. A., Hudecki, M. S., Pollina, C. M., and Gosselin, L. E. (2001) Impact of prednisone on TGF-β1 and collagen in diaphragm muscle from mdx mice. Muscle Nerve 24, 428-432
    • (2001) Muscle Nerve , vol.24 , pp. 428-432
    • Hartel, J.V.1    Granchelli, J.A.2    Hudecki, M.S.3    Pollina, C.M.4    Gosselin, L.E.5
  • 51
    • 0029153067 scopus 로고
    • Expression of transforming growth factor-β1 in dystrophic patient muscles correlates with fibrosis: Pathogenetic role of a fibrogenic cytokine. J
    • Bernasconi, P., Torchiana, E., Confalonieri, P., Brugnoni, R., Barresi, R., Mora, M., Cornelio, F., Morandi, L., and Mantegazza, R. (1995) Expression of transforming growth factor-β1 in dystrophic patient muscles correlates with fibrosis: pathogenetic role of a fibrogenic cytokine. J. Clin. Invest. 96, 1137-1144
    • (1995) Clin. Invest. , vol.96 , pp. 1137-1144
    • Bernasconi, P.1    Torchiana, E.2    Confalonieri, P.3    Brugnoni, R.4    Barresi, R.5    Mora, M.6    Cornelio, F.7    Morandi, L.8    Mantegazza, R.9
  • 53
    • 0036965929 scopus 로고    scopus 로고
    • TGF-beta and the Smad signal transduction pathway
    • Mehra, A., and Wrana, J. L. (2002) TGF-beta and the Smad signal transduction pathway. Biochem. Cell Biol. 80, 605-622
    • (2002) Biochem. Cell Biol. , vol.80 , pp. 605-622
    • Mehra, A.1    Wrana, J.L.2
  • 54
    • 84914106428 scopus 로고    scopus 로고
    • Role of flowsensitive microRNAs in endothelial dysfunction and atherosclerosis: Mechanosensitive athero-miRs
    • Kumar, S., Kim, C. W., Simmons, R. D., and Jo, H. (2014) Role of flowsensitive microRNAs in endothelial dysfunction and atherosclerosis: mechanosensitive athero-miRs. Arterioscler. Thromb. Vasc. Biol. 34, 2206-2216
    • (2014) Arterioscler. Thromb. Vasc. Biol. , vol.34 , pp. 2206-2216
    • Kumar, S.1    Kim, C.W.2    Simmons, R.D.3    Jo, H.4
  • 57
    • 36749026211 scopus 로고    scopus 로고
    • Modified patient stem cells as prelude to autologous treatment of muscular dystrophy
    • Davies, K. E., and Grounds, M. D. (2007) Modified patient stem cells as prelude to autologous treatment of muscular dystrophy. Cell Stem Cell 1, 595-596
    • (2007) Cell Stem Cell , vol.1 , pp. 595-596
    • Davies, K.E.1    Grounds, M.D.2
  • 58
    • 84867004601 scopus 로고    scopus 로고
    • TGFβ signaling: Its role in fibrosis formation and myopathies
    • MacDonald, E. M., and Cohn, R. D. (2012) TGFβ signaling: its role in fibrosis formation and myopathies. Curr. Opin. Rheumatol. 24, 628-634
    • (2012) Curr. Opin. Rheumatol. , vol.24 , pp. 628-634
    • MacDonald, E.M.1    Cohn, R.D.2
  • 59
    • 33749248495 scopus 로고    scopus 로고
    • Congenital muscular dystrophies and the extracellular matrix
    • Schessl, J., Zou, Y., and Bönnemann, C. G. (2006) Congenital muscular dystrophies and the extracellular matrix. Semin. Pediatr. Neurol. 13, 80-89
    • (2006) Semin. Pediatr. Neurol. , vol.13 , pp. 80-89
    • Schessl, J.1    Zou, Y.2    Bönnemann, C.G.3
  • 61
    • 68249155413 scopus 로고    scopus 로고
    • Endomysial fibrosis in Duchenne muscular dystrophy: A marker of poor outcome associated with macrophage alternative activation. J
    • Desguerre, I., Mayer, M., Leturcq, F., Barbet, J. P., Gherardi, R. K., and Christov, C (2009) Endomysial fibrosis in Duchenne muscular dystrophy: a marker of poor outcome associated with macrophage alternative activation. J. Neuropathol. Exp. Neurol. 68, 762-773
    • (2009) Neuropathol. Exp. Neurol. , vol.68 , pp. 762-773
    • Desguerre, I.1    Mayer, M.2    Leturcq, F.3    Barbet, J.P.4    Gherardi, R.K.5    Christov, C.6
  • 62
    • 0028359187 scopus 로고
    • Expression of transforming growth factor-β1 and its relation to endomysial fibrosis in progressive muscular dystrophy
    • Yamazaki, M., Minota, S., Sakurai, H, Miyazono, K., Yamada, A., Kanazawa, I., and Kawai, M. (1994) Expression of transforming growth factor-β1 and its relation to endomysial fibrosis in progressive muscular dystrophy. Am. J. Pathol. 144, 221-226
    • (1994) Am. J. Pathol. , vol.144 , pp. 221-226
    • Yamazaki, M.1    Minota, S.2    Sakurai, H.3    Miyazono, K.4    Yamada, A.5    Kanazawa, I.6    Kawai, M.7
  • 65
    • 33746318677 scopus 로고    scopus 로고
    • Immunomodulation of TGF-β1 in mdx mouse inhibits connective tissue proliferation in diaphragm but increases inflammatory response: Implications for antifibrotic therapy. J
    • Andreetta, F., Bernasconi, P., Baggi, F., Ferro, P., Oliva, L., Arnoldi, E., Cornelio, F., Mantegazza, R., and Confalonieri, P. (2006) Immunomodulation of TGF-β1 in mdx mouse inhibits connective tissue proliferation in diaphragm but increases inflammatory response: implications for antifibrotic therapy. J. Neuroimmunol. 175, 77-86
    • (2006) Neuroimmunol. , vol.175 , pp. 77-86
    • Andreetta, F.1    Bernasconi, P.2    Baggi, F.3    Ferro, P.4    Oliva, L.5    Arnoldi, E.6    Cornelio, F.7    Mantegazza, R.8    Confalonieri, P.9
  • 66
    • 36448936383 scopus 로고    scopus 로고
    • TGF β-SMAD signal transduction: Molecular specificity and functional flexibility
    • Schmierer, B., and Hill, C. S. (2007) TGF β-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev. Mol. Cell Biol. 8, 970-982
    • (2007) Nat Rev. Mol. Cell Biol. , vol.8 , pp. 970-982
    • Schmierer, B.1    Hill, C.S.2
  • 70
    • 52949091534 scopus 로고    scopus 로고
    • The let-7 family of microRNAs
    • Roush, S., and Slack, F. J. (2008) The let-7 family of microRNAs. Trends Cell Biol. 18, 505-516
    • (2008) Trends Cell Biol. , vol.18 , pp. 505-516
    • Roush, S.1    Slack, F.J.2
  • 72
    • 79952514373 scopus 로고    scopus 로고
    • The type II poly (A)-binding protein PABP-2 genetically interacts with the let-7 miRNA and elicits heterochronic phenotypes in Caenorhabditis elegans
    • Hurschler, B. A., Harris, D. T., and Grosshans, H. (2011) The type II poly (A)-binding protein PABP-2 genetically interacts with the let-7 miRNA and elicits heterochronic phenotypes in Caenorhabditis elegans. Nucleic Acids Res. 39, 5647-5657
    • (2011) Nucleic Acids Res. , vol.39 , pp. 5647-5657
    • Hurschler, B.A.1    Harris, D.T.2    Grosshans, H.3
  • 76
    • 0028127264 scopus 로고
    • Inferences on passive diaphragm mechanics from gross anatomy
    • Boriek, A. M., and Rodarte, J. R. (1994) Inferences on passive diaphragm mechanics from gross anatomy. J. Appl. Physiol. 77, 2065-2070
    • (1994) J. Appl. Physiol. , vol.77 , pp. 2065-2070
    • Boriek, A.M.1    Rodarte, J.R.2


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