The type II poly(A)-binding protein PABP-2 genetically interacts with the let-7 miRNA and elicits heterochronic phenotypes in Caenorhabditis elegans

Nucleic Acids Research

Volumn 39, Issue 13, 2011, Pages 5647-5657

  Hurschler, Benjamin A ^a   Harris, David T ^b   Großhans, Helge ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MICRORNA; POLYADENYLIC ACID BINDING PROTEIN;

BIOGENESIS; CAENORHABDITIS ELEGANS; CELL DIFFERENTIATION; CELL FATE; CONTROLLED STUDY; EPISTASIS; GENE; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE INTERACTION; GENE SILENCING; LET 7 GENE; NONHUMAN; PABP 2 GENE; PARASITE VIABILITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN INTERACTION; REGULATORY MECHANISM; REVIEW; RNA INTERFERENCE; RNA METABOLISM; RNA TRANSLATION;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL FUSION; DNA-BINDING PROTEINS; MICRORNAS; PHENOTYPE; POLY(A)-BINDING PROTEINS; PROTEIN BIOSYNTHESIS; RNA INTERFERENCE; RNA STABILITY; RNA, MESSENGER; TRANSCRIPTION FACTORS;

ANIMALIA; CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 79952514373     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr145     Document Type: Review

References (46)

1. Fabian, M.R., Sonenberg, N. and Filipowicz, W. (2010) Regulation of mRNA translation and stability by microRNAs. Annu. Rev. Biochem., 79, 351-379.
2. Lagos-Quintana, M., Rauhut, R., Lendeckel, W. and Tuschl, T. (2001) Identification of novel genes coding for small expressed RNAs. Science, 294, 853-858. (Pubitemid 33032103)
3. Pasquinelli, A.E., Reinhart, B.J., Slack, F., Martindale, M.Q., Kuroda, M.I., Maller, B., Hayward, D.C., Ball, E.E., Degnan, B., Muller, P. et al. (2000) Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature, 408, 86-89.
4. Reinhart, B.J., Slack, F.J., Basson, M., Pasquinelli, A.E., Bettinger, J.C., Rougvie, A.E., Horvitz, H.R. and Ruvkun, G. (2000) The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature, 403, 901-906. (Pubitemid 30130993)
5. Rougvie, A.E. (2005) Intrinsic and extrinsic regulators of developmental timing: from miRNAs to nutritional cues. Development, 132, 3787-3798. (Pubitemid 41410245)
6. Slack, F.J., Basson, M., Liu, Z., Ambros, V., Horvitz, H.R. and Ruvkun, G. (2000) The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol. Cell, 5, 659-669.
7. Bü ssing, I., Slack, F.J. and Großhans, H. (2008) let-7 microRNAs in development, stem cells and cancer. Trends Mol. Med., 14, 400-409.
8. Ding, X.C., Slack, F.J. and Großhans, H. (2008) The let-7 microRNA interfaces extensively with the translation machinery to regulate cell differentiation. Cell Cycle, 7, 3083-3090.
9. Fabian, M.R., Mathonnet, G., Sundermeier, T., Mathys, H., Zipprich, J.T., Svitkin, Y.V., Rivas, F., Jinek, M., Wohlschlegel, J., Doudna, J.A. et al. (2009) Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation. Mol. Cell, 35, 868-880.
10. Zekri, L., Huntzinger, E., Heimstä dt, S. and Izaurralde, E. (2009) The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release. Mol. Cell. Biol., 29, 6220-6231.
11. Walters, R.W., Bradrick, S.S. and Gromeier, M. (2010) Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression. RNA, 16, 239-250.
12. Wahle, E. (1991) A novel poly(A)-binding protein acts as a specificity factor in the second phase of messenger RNA polyadenylation. Cell, 66, 759-768. (Pubitemid 121001709)
13. Bienroth, S., Keller, W. and Wahle, E. (1993) Assembly of a processive messenger RNA polyadenylation complex. EMBO J., 12, 585-594. (Pubitemid 23073704)
14. Beilharz, T.H. and Preiss, T. (2007) Widespread use of poly(A) tail length control to accentuate expression of the yeast transcriptome. RNA, 13, 982-997. (Pubitemid 46984890)
15. Millevoi, S. and Vagner, S. (2009) Molecular mechanisms of eukaryotic pre-mRNA 30 end processing regulation. Nucleic Acids Res., 38, 2757-2774.
16. Parker, R. and Song, H. (2004) The enzymes and control of eukaryotic mRNA turnover. Nat. Struct. Mol. Biol., 11, 121-127. (Pubitemid 38146514)
17. Kuhn, U., Gundel, M., Knoth, A., Kerwitz, Y., Rudel, S. and Wahle, E. (2009) Poly(A) tail length is controlled by the nuclear poly(A)-binding protein regulating the interaction between poly(A) polymerase and the cleavage and polyadenylation specificity factor. J. Biol. Chem., 284, 22803-22814.
18. Wahle, E. (1995) Poly(A) tail length control is caused by termination of processive synthesis. J. Biol. Chem., 270, 2800-2808.
19. Apponi, L.H., Leung, S.W., Williams, K.R., Valentini, S.R., Corbett, A.H. and Pavlath, G.K. (2010) Loss of nuclear poly(A)-binding protein 1 causes defects in myogenesis and mRNA biogenesis. Hum. Mol. Genet., 19, 1058-1065.
20. Benoit, B., Mitou, G., Chartier, A., Temme, C., Zaessinger, S., Wahle, E., Busseau, I. and Simonelig, M. (2005) An essential cytoplasmic function for the nuclear poly(A) binding protein, PABP2, in poly(A) tail length control and early development in Drosophila. Dev. Cell, 9, 511-522. (Pubitemid 41430734)
21. Perreault, A., Lemieux, C. and Bachand, F. (2007) Regulation of the nuclear poly(A)-binding protein by arginine methylation in fission yeast. J. Biol. Chem., 282, 7552-7562. (Pubitemid 47093634)
22. Lemay, J.F., D'Amours, A., Lemieux, C., Lackner, D.H., St-Sauveur, V.G., Bahler, J. and Bachand, F. (2010) The nuclear poly(A)-binding protein interacts with the exosome to promote synthesis of noncoding small nucleolar RNAs. Mol. Cell, 37, 34-45.
23. Lemay, J.F., Lemieux, C., St-Andre, O. and Bachand, F. (2010) Crossing the borders: Poly(A)-binding proteins working on both sides of the fence. RNA Biol., 7, 291-295.
24. Brais, B., Bouchard, J.P., Xie, Y.G., Rochefort, D.L., Chretien, N., Tome, F.M., Lafreniere, R.G., Rommens, J.M., Uyama, E., Nohira, O. et al. (1998) Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy. Nat. Genet., 18, 164-167. (Pubitemid 28082465)
25. Brenner, S. (1974) The genetics of Caenorhabditis elegans. Genetics, 77, 71-94.
26. Mohler, W.A., Simske, J.S., Williams-Masson, E.M., Hardin, J.D. and White, J.G. (1998) Dynamics and ultrastructure of developmental cell fusions in the Caenorhabditis elegans hypodermis. Curr. Biol., 8, 1087-1090. (Pubitemid 28451034)
27. Großhans, H., Johnson, T., Reinert, K.L., Gerstein, M. and Slack, F.J. (2005) The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans. Dev. Cell, 8, 321-330. (Pubitemid 40309803)
28. Kamath, R.S., Fraser, A.G., Dong, Y., Poulin, G., Durbin, R., Gotta, M., Kanapin, A., Le Bot, N., Moreno, S., Sohrmann, M. et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature, 421, 231-237. (Pubitemid 36139121)
29. Rual, J.F., Ceron, J., Koreth, J., Hao, T., Nicot, A.S., Hirozane-Kishikawa, T., Vandenhaute, J., Orkin, S.H., Hill, D.E., van den Heuvel, S. et al. (2004) Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. Genome Res., 14, 2162-2168. (Pubitemid 39440199)
30. Ding, X.C. and Großhans, H. (2009) Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins. EMBO J., 28, 213-222.
31. Livak, K.J. and Schmittgen, T.D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods, 25, 402-408. (Pubitemid 34164012)
32. Pall, G.S. and Hamilton, A.J. (2008) Improved northern blot method for enhanced detection of small RNA. Nat. Protoc., 3, 1077-1084. (Pubitemid 351818694)
33. Schagger, H. (2006) Tricine-SDS-PAGE. Nat. Protoc., 1, 16-22.
34. Abramoff, M., Magelhaes, P. and Ram, S. (2004) Image Processing with ImageJ. Biophotonics Int., 11, 36-42.
35. Vella, M.C., Choi, E.Y., Lin, S.Y., Reinert, K. and Slack, F.J. (2004) The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 30UTR. Genes Dev., 18, 132-137. (Pubitemid 38141781)
36. Bettinger, J.C., Lee, K. and Rougvie, A.E. (1996) Stage-specific accumulation of the terminal differentiation factor LIN-29 during Caenorhabditis elegans development. Development, 122, 2517-2527.
37. Rougvie, A.E. and Ambros, V. (1995) The heterochronic gene lin-29 encodes a zinc finger protein that controls a terminal differentiation event in Caenorhabditis elegans. Development, 121, 2491-2500.
38. Abbott, A.L., Alvarez-Saavedra, E., Miska, E.A., Lau, N.C., Bartel, D.P., Horvitz, H.R. and Ambros, V. (2005) The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev. Cell, 9, 403-414. (Pubitemid 41235809)
39. Liu, Z., Kirch, S. and Ambros, V. (1995) The Caenorhabditis elegans heterochronic gene pathway controls stage-specific transcription of collagen genes. Development, 121, 2471-2478.
40. Rehmsmeier, M., Steffen, P., Hochsmann, M. and Giegerich, R. (2004) Fast and effective prediction of microRNA/target duplexes. RNA, 10, 1507-1517. (Pubitemid 39288185)
41. Bagga, S., Bracht, J., Hunter, S., Massirer, K., Holtz, J., Eachus, R. and Pasquinelli, A.E. (2005) Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell, 122, 553-563. (Pubitemid 41191154)
42. Abrahante, J.E., Daul, A.L., Li, M., Volk, M.L., Tennessen, J.M., Miller, E.A. and Rougvie, A.E. (2003) The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev. Cell, 4, 625-637. (Pubitemid 36564894)
43. Lin, S.Y., Johnson, S.M., Abraham, M., Vella, M.C., Pasquinelli, A., Gamberi, C., Gottlieb, E. and Slack, F.J. (2003) The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target. Dev. Cell, 4, 639-650. (Pubitemid 36564895)
44. Moss, E.G., Lee, R.C. and Ambros, V. (1997) The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell, 88, 637-646. (Pubitemid 27152406)
45. Wightman, B., Ha, I. and Ruvkun, G. (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell, 75, 855-862. (Pubitemid 24014543)
46. Bracht, J., Hunter, S., Eachus, R., Weeks, P. and Pasquinelli, A.E. (2004) Trans-splicing and polyadenylation of let-7 microRNA primary transcripts. RNA, 10, 1586-1594. (Pubitemid 39288193)