Phloretin induces apoptosis of non-small cell lung carcinoma A549 cells via JNK1/2 and p38 MAPK pathways

Oncology Reports

Volumn 34, Issue 6, 2015, Pages 2871-2879

  Min, Jie ^a   Li, Xu ^a   Huang, Kenan ^a   Tang, Hua ^a   Ding, Xinyu ^a   Qi, Chen ^a   Qin, Xiong ^b   Xu, Zhifei ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Lung cancer; Migration; P38 MAPK; Phloretin; Ppoptosis

Indexed keywords

CASPASE 3; CASPASE 9; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHLORETIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 9;

A549 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOASSAY; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LOW DRUG DOSE; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; PHYTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; CARCINOMA, NON-SMALL-CELL LUNG; CELL MOTION; CELL PROLIFERATION; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASE 9; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHLORETIN; PHOSPHORYLATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84943767245     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.4325     Document Type: Article

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