-
1
-
-
84920177145
-
The heritability of prostate cancer in the Nordic Twin Study of Cancer
-
Hjelmborg, J.B., Scheike, T., Holst, K., Skytthe, A., Penney, K.L., Graff, R.E., Pukkala, E., Christensen, K., Adami, H.O., Holm, N.V. et al. (2014) The heritability of prostate cancer in the Nordic Twin Study of Cancer. Cancer Epidemiol. Biomarkers Prev., 23, 2303-2312.
-
(2014)
Cancer Epidemiol. Biomarkers Prev.
, vol.23
, pp. 2303-2312
-
-
Hjelmborg, J.B.1
Scheike, T.2
Holst, K.3
Skytthe, A.4
Penney, K.L.5
Graff, R.E.6
Pukkala, E.7
Christensen, K.8
Adami, H.O.9
Holm, N.V.10
-
2
-
-
84896107555
-
Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease
-
Leongamornlert, D., Saunders, E., Dadaev, T., Tymrakiewicz, M., Goh, C., Jugurnauth-Little, S., Kozarewa, I., Fenwick, K., Assiotis, I., Barrowdale, D. et al. (2014) Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease. Br. J. Cancer, 110, 1663-1672.
-
(2014)
Br. J. Cancer
, vol.110
, pp. 1663-1672
-
-
Leongamornlert, D.1
Saunders, E.2
Dadaev, T.3
Tymrakiewicz, M.4
Goh, C.5
Jugurnauth-Little, S.6
Kozarewa, I.7
Fenwick, K.8
Assiotis, I.9
Barrowdale, D.10
-
3
-
-
84856176782
-
Germline mutations in HOXB13 and prostatecancer risk
-
Ewing, C.M., Ray, A.M., Lange, E.M., Zuhlke, K.A., Robbins, C.M., Tembe, W.D., Wiley, K.E., Isaacs, S.D., Johng, D., Wang, Y. et al. (2012) Germline mutations in HOXB13 and prostatecancer risk. N. Engl. J. Med., 366, 141-149.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 141-149
-
-
Ewing, C.M.1
Ray, A.M.2
Lange, E.M.3
Zuhlke, K.A.4
Robbins, C.M.5
Tembe, W.D.6
Wiley, K.E.7
Isaacs, S.D.8
Johng, D.9
Wang, Y.10
-
4
-
-
84922011640
-
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer
-
Al Olama, A.A., Kote-Jarai, Z., Berndt, S.I., Conti, D.V., Schumacher, F., Han, Y., Benlloch, S., Hazelett, D.J.,Wang, Z., Saunders, E. et al. (2014) A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. Nat. Genet., 46, 1103-1109.
-
(2014)
Nat. Genet.
, vol.46
, pp. 1103-1109
-
-
Al Olama, A.A.1
Kote-Jarai, Z.2
Berndt, S.I.3
Conti, D.V.4
Schumacher, F.5
Han, Y.6
Benlloch, S.7
Hazelett, D.J.8
Wang, Z.9
Saunders, E.10
-
5
-
-
79959731094
-
Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript
-
Kote-Jarai, Z., Amin Al Olama, A., Leongamornlert, D., Tymrakiewicz, M., Saunders, E., Guy, M., Giles, G.G., Severi, G., Southey, M., Hopper, J.L. et al. (2011) Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript. Hum. Genet., 129, 687-694.
-
(2011)
Hum. Genet.
, vol.129
, pp. 687-694
-
-
Kote-Jarai, Z.1
Al Olama, A.A.2
Leongamornlert, D.3
Tymrakiewicz, M.4
Saunders, E.5
Guy, M.6
Giles, G.G.7
Severi, G.8
Southey, M.9
Hopper, J.L.10
-
6
-
-
84878451270
-
Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression
-
Kote-Jarai, Z., Saunders, E.J., Leongamornlert, D.A., Tymrakiewicz, M., Dadaev, T., Jugurnauth-Little, S., Ross-Adams, H., Al Olama, A.A., Benlloch, S., Halim, S. et al. (2013) Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression. Hum. Mol. Genet., 22, 2520-2528.
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 2520-2528
-
-
Kote-Jarai, Z.1
Saunders, E.J.2
Leongamornlert, D.A.3
Tymrakiewicz, M.4
Dadaev, T.5
Jugurnauth-Little, S.6
Ross-Adams, H.7
Al Olama, A.A.8
Benlloch, S.9
Halim, S.10
-
7
-
-
70349548806
-
Multiple loci on 8q24 associated with prostate cancer susceptibility
-
Al Olama, A.A., Kote-Jarai, Z., Giles, G.G., Guy, M., Morrison, J., Severi, G., Leongamornlert, D.A., Tymrakiewicz, M., Jhavar, S., Saunders, E. et al. (2009) Multiple loci on 8q24 associated with prostate cancer susceptibility. Nat. Genet., 41, 1058-1060.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1058-1060
-
-
Al Olama, A.A.1
Kote-Jarai, Z.2
Giles, G.G.3
Guy, M.4
Morrison, J.5
Severi, G.6
Leongamornlert, D.A.7
Tymrakiewicz, M.8
Jhavar, S.9
Saunders, E.10
-
8
-
-
84862825777
-
Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese
-
Akamatsu, S., Takata, R., Haiman, C.A., Takahashi, A., Inoue, T., Kubo, M., Furihata, M., Kamatani, N., Inazawa, J., Chen, G.K. et al. (2012) Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese. Nat. Genet., 44, 426-429. S421.
-
(2012)
Nat. Genet.
, vol.44
, pp. 426-429. S421
-
-
Akamatsu, S.1
Takata, R.2
Haiman, C.A.3
Takahashi, A.4
Inoue, T.5
Kubo, M.6
Furihata, M.7
Kamatani, N.8
Inazawa, J.9
Chen, G.K.10
-
9
-
-
77956637724
-
Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population
-
Takata, R., Akamatsu, S., Kubo, M., Takahashi, A., Hosono, N., Kawaguchi, T., Tsunoda, T., Inazawa, J., Kamatani, N., Ogawa, O. et al. (2010) Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population. Nat. Genet., 42, 751-754.
-
(2010)
Nat. Genet.
, vol.42
, pp. 751-754
-
-
Takata, R.1
Akamatsu, S.2
Kubo, M.3
Takahashi, A.4
Hosono, N.5
Kawaguchi, T.6
Tsunoda, T.7
Inazawa, J.8
Kamatani, N.9
Ogawa, O.10
-
10
-
-
84868206960
-
Genome-wide association study in Chinese men identifies two newprostate cancer risk loci at 9q31.2 and 19q13.4
-
Xu, J., Mo, Z., Ye, D.,Wang, M., Liu, F., Jin, G., Xu, C.,Wang, X., Shao, Q., Chen, Z. et al. (2012) Genome-wide association study in Chinese men identifies two newprostate cancer risk loci at 9q31.2 and 19q13.4. Nat. Genet., 44, 1231-1235.
-
(2012)
Nat. Genet.
, vol.44
, pp. 1231-1235
-
-
Xu, J.1
Mo, Z.2
Ye, D.3
Wang, M.4
Liu, F.5
Jin, G.6
Xu, C.7
Wang, X.8
Shao, Q.9
Chen, Z.10
-
11
-
-
38449103390
-
Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP
-
Duggan, D., Zheng, S.L., Knowlton, M., Benitez, D., Dimitrov, L., Wiklund, F., Robbins, C., Isaacs, S.D., Cheng, Y., Li, G. et al. (2007) Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP. J. Natl. Cancer Inst., 99, 1836-1844.
-
(2007)
J. Natl. Cancer Inst.
, vol.99
, pp. 1836-1844
-
-
Duggan, D.1
Zheng, S.L.2
Knowlton, M.3
Benitez, D.4
Dimitrov, L.5
Wiklund, F.6
Robbins, C.7
Isaacs, S.D.8
Cheng, Y.9
Li, G.10
-
12
-
-
84875739291
-
Identification of 23 newprostate cancer susceptibility loci using the iCOGS customgenotyping array
-
391e381-382
-
Eeles, R.A., Olama, A.A., Benlloch, S., Saunders, E.J., Leongamornlert, D.A., Tymrakiewicz, M., Ghoussaini, M., Luccarini, C., Dennis, J., Jugurnauth-Little, S. et al. (2013) Identification of 23 newprostate cancer susceptibility loci using the iCOGS customgenotyping array. Nat. Genet., 45, 385-391, 391e381-382.
-
(2013)
Nat. Genet.
, vol.45
, pp. 385-391
-
-
Eeles, R.A.1
Olama, A.A.2
Benlloch, S.3
Saunders, E.J.4
Leongamornlert, D.A.5
Tymrakiewicz, M.6
Ghoussaini, M.7
Luccarini, C.8
Dennis, J.9
Jugurnauth-Little, S.10
-
13
-
-
79960924160
-
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study
-
Kote-Jarai, Z., Olama, A.A., Giles, G.G., Severi, G., Schleutker, J., Weischer, M., Campa, D., Riboli, E., Key, T., Gronberg, H. et al. (2011) Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat. Genet., 43, 785-791.
-
(2011)
Nat. Genet.
, vol.43
, pp. 785-791
-
-
Kote-Jarai, Z.1
Olama, A.A.2
Giles, G.G.3
Severi, G.4
Schleutker, J.5
Weischer, M.6
Campa, D.7
Riboli, E.8
Key, T.9
Gronberg, H.10
-
14
-
-
84896695503
-
Comprehensive functional annotation of 77 prostate cancer risk loci
-
Ellipse/GAME-ON Consortium, Practical Consortium
-
Hazelett, D.J., Rhie, S.K., Gaddis, M., Yan, C., Lakeland, D.L., Coetzee, S.G., Ellipse/GAME-ON Consortium, Practical Consortium, Henderson, B.E., Noushmehr, H., Cozen, W., Kote-Jarai, Z. et al. (2014) Comprehensive functional annotation of 77 prostate cancer risk loci. PLoS Genet., 10, e1004102.
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004102
-
-
Hazelett, D.J.1
Rhie, S.K.2
Gaddis, M.3
Yan, C.4
Lakeland, D.L.5
Coetzee, S.G.6
Henderson, B.E.7
Noushmehr, H.8
Cozen, W.9
Kote-Jarai, Z.10
-
15
-
-
80054761058
-
Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1
-
Cai, C., He, H.H., Chen, S., Coleman, I., Wang, H., Fang, Z., Chen, S., Nelson, P.S., Liu, X.S., Brown, M. et al. (2011) Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1. Cancer Cell, 20, 457-471.
-
(2011)
Cancer Cell
, vol.20
, pp. 457-471
-
-
Cai, C.1
He, H.H.2
Chen, S.3
Coleman, I.4
Wang, H.5
Fang, Z.6
Chen, S.7
Nelson, P.S.8
Liu, X.S.9
Brown, M.10
-
16
-
-
39749129053
-
Multiple newly identified loci associated with prostate cancer susceptibility
-
Eeles, R.A., Kote-Jarai, Z., Giles, G.G., Olama, A.A., Guy, M., Jugurnauth, S.K., Mulholland, S., Leongamornlert, D.A., Edwards, S.M., Morrison, J. et al. (2008) Multiple newly identified loci associated with prostate cancer susceptibility. Nat. Genet., 40, 316-321.
-
(2008)
Nat. Genet.
, vol.40
, pp. 316-321
-
-
Eeles, R.A.1
Kote-Jarai, Z.2
Giles, G.G.3
Olama, A.A.4
Guy, M.5
Jugurnauth, S.K.6
Mulholland, S.7
Leongamornlert, D.A.8
Edwards, S.M.9
Morrison, J.10
-
17
-
-
70349545839
-
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
-
Eeles, R.A., Kote-Jarai, Z., Al Olama, A.A., Giles, G.G., Guy, M., Severi, G., Muir, K., Hopper, J.L., Henderson, B.E., Haiman, C.A. et al. (2009) Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat. Genet., 41, 1116-1121.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1116-1121
-
-
Eeles, R.A.1
Kote-Jarai, Z.2
Al Olama, A.A.3
Giles, G.G.4
Guy, M.5
Severi, G.6
Muir, K.7
Hopper, J.L.8
Henderson, B.E.9
Haiman, C.A.10
-
18
-
-
79959841849
-
Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer
-
Chung, C.C., Ciampa, J., Yeager, M., Jacobs, K.B., Berndt, S.I., Hayes, R.B., Gonzalez-Bosquet, J., Kraft, P., Wacholder, S., Orr, N. et al. (2011) Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer. Hum. Mol. Genet., 20, 2869-2878.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2869-2878
-
-
Chung, C.C.1
Ciampa, J.2
Yeager, M.3
Jacobs, K.B.4
Berndt, S.I.5
Hayes, R.B.6
Gonzalez-Bosquet, J.7
Kraft, P.8
Wacholder, S.9
Orr, N.10
-
19
-
-
52949115663
-
Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12
-
Sun, J., Zheng, S.L.,Wiklund, F., Isaacs, S.D., Purcell, L.D., Gao, Z., Hsu, F.C., Kim, S.T., Liu,W., Zhu, Y. et al. (2008) Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12. Nat. Genet., 40, 1153-1155.
-
(2008)
Nat. Genet.
, vol.40
, pp. 1153-1155
-
-
Sun, J.1
Zheng, S.L.2
Wiklund, F.3
Isaacs, S.D.4
Purcell, L.D.5
Gao, Z.6
Hsu, F.C.7
Kim, S.T.8
Liu, W.9
Zhu, Y.10
-
20
-
-
70349547128
-
Genome- wide association and replication studies identify four variants associated with prostate cancer susceptibility
-
Gudmundsson, J., Sulem, P., Gudbjartsson, D.F., Blondal, T., Gylfason, A., Agnarsson, B.A., Benediktsdottir, K.R., Magnusdottir, D.N., Orlygsdottir, G., Jakobsdottir, M. et al. (2009) Genome- wide association and replication studies identify four variants associated with prostate cancer susceptibility. Nat. Genet., 41, 1122-1126.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1122-1126
-
-
Gudmundsson, J.1
Sulem, P.2
Gudbjartsson, D.F.3
Blondal, T.4
Gylfason, A.5
Agnarsson, B.A.6
Benediktsdottir, K.R.7
Magnusdottir, D.N.8
Orlygsdottir, G.9
Jakobsdottir, M.10
-
21
-
-
84865792756
-
The P2X7 receptor is a key modulator of aerobic glycolysis
-
Amoroso, F., Falzoni, S., Adinolfi, E., Ferrari, D. and Di Virgilio, F. (2012) The P2X7 receptor is a key modulator of aerobic glycolysis. Cell Death Dis., 3, e370.
-
(2012)
Cell Death Dis.
, vol.3
, pp. e370
-
-
Amoroso, F.1
Falzoni, S.2
Adinolfi, E.3
Ferrari, D.4
Di Virgilio, F.5
-
22
-
-
84255162057
-
Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism
-
Hitosugi, T., Fan, J., Chung, T.W., Lythgoe, K.,Wang, X., Xie, J., Ge, Q., Gu, T.L., Polakiewicz, R.D., Roesel, J.L. et al. (2011) Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism. Mol. Cell, 44, 864-877.
-
(2011)
Mol. Cell
, vol.44
, pp. 864-877
-
-
Hitosugi, T.1
Fan, J.2
Chung, T.W.3
Lythgoe, K.4
Wang, X.5
Xie, J.6
Ge, Q.7
Gu, T.L.8
Polakiewicz, R.D.9
Roesel, J.L.10
-
23
-
-
1542327681
-
NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate
-
Bera, T.K., Das, S., Maeda, H., Beers, R.,Wolfgang, C.D., Kumar, V., Hahn, Y., Lee, B. and Pastan, I. (2004) NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate. Proc. Natl. Acad. Sci. USA, 101, 3059-3064.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3059-3064
-
-
Bera, T.K.1
Das, S.2
Maeda, H.3
Beers, R.4
Wolfgang, C.D.5
Kumar, V.6
Hahn, Y.7
Lee, B.8
Pastan, I.9
-
24
-
-
51049091445
-
Topology of NGEP, a prostate-specific cell:cell junction protein widely expressed in many cancers of different grade level
-
Das, S., Hahn, Y., Walker, D.A., Nagata, S., Willingham, M.C., Peehl, D.M., Bera, T.K., Lee, B. and Pastan, I. (2008) Topology of NGEP, a prostate-specific cell:cell junction protein widely expressed in many cancers of different grade level. Cancer Res., 68, 6306-6312.
-
(2008)
Cancer Res.
, vol.68
, pp. 6306-6312
-
-
Das, S.1
Hahn, Y.2
Walker, D.A.3
Nagata, S.4
Willingham, M.C.5
Peehl, D.M.6
Bera, T.K.7
Lee, B.8
Pastan, I.9
-
25
-
-
84885871270
-
Reduced expression of NGEP is associated with high-grade prostate cancers: a tissue microarray analysis
-
Mohsenzadegan, M., Madjd, Z., Asgari, M., Abolhasani, M., Shekarabi, M., Taeb, J. and Shariftabrizi, A. (2013) Reduced expression of NGEP is associated with high-grade prostate cancers: a tissue microarray analysis. Cancer Immunol. Immunother., 62, 1609-1618.
-
(2013)
Cancer Immunol. Immunother.
, vol.62
, pp. 1609-1618
-
-
Mohsenzadegan, M.1
Madjd, Z.2
Asgari, M.3
Abolhasani, M.4
Shekarabi, M.5
Taeb, J.6
Shariftabrizi, A.7
-
26
-
-
84885516070
-
Germline mutation in the RAD51B gene confers predisposition to breast cancer
-
Golmard, L., Caux-Moncoutier, V., Davy, G., Al Ageeli, E., Poirot, B., Tirapo, C., Michaux, D., Barbaroux, C., d'Enghien, C.D., Nicolas, A. et al. (2013) Germline mutation in the RAD51B gene confers predisposition to breast cancer. BMC Cancer, 13, 484.
-
(2013)
BMC Cancer
, vol.13
, pp. 484
-
-
Golmard, L.1
Caux-Moncoutier, V.2
Davy, G.3
Al Ageeli, E.4
Poirot, B.5
Tirapo, C.6
Michaux, D.7
Barbaroux, C.8
d'Enghien, C.D.9
Nicolas, A.10
-
27
-
-
84868207237
-
Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk
-
Orr, N., Lemnrau, A., Cooke, R., Fletcher, O., Tomczyk, K., Jones, M., Johnson, N., Lord, C.J., Mitsopoulos, C., Zvelebil, M. et al. (2012) Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk. Nat. Genet., 44, 1182-1184.
-
(2012)
Nat. Genet.
, vol.44
, pp. 1182-1184
-
-
Orr, N.1
Lemnrau, A.2
Cooke, R.3
Fletcher, O.4
Tomczyk, K.5
Jones, M.6
Johnson, N.7
Lord, C.J.8
Mitsopoulos, C.9
Zvelebil, M.10
-
28
-
-
77953670889
-
Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer
-
Harries, L.W., Perry, J.R., McCullagh, P. and Crundwell, M. (2010) Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer. BMC Cancer, 10, 315.
-
(2010)
BMC Cancer
, vol.10
, pp. 315
-
-
Harries, L.W.1
Perry, J.R.2
McCullagh, P.3
Crundwell, M.4
-
29
-
-
84896544856
-
Variants at IRX4 as prostate cancer expression quantitative trait loci
-
Xu,X., Hussain,W.M., Vijai, J., Offit, K., Rubin,M.A.,Demichelis, F. and Klein, R.J. (2014) Variants at IRX4 as prostate cancer expression quantitative trait loci. Eur. J. Hum. Genet., 22, 558-563.
-
(2014)
Eur. J. Hum. Genet.
, vol.22
, pp. 558-563
-
-
Xu, X.1
Hussain, W.M.2
Vijai, J.3
Offit, K.4
Rubin, M.A.5
Demichelis, F.6
Klein, R.J.7
-
30
-
-
84964315018
-
Expression QTL-based analyses reveal candidate causal genes andlociacrossfivetumor types
-
Li, Q., Stram, A., Chen, C., Kar, S., Gayther, S., Pharoah, P., Haiman, C., Stranger, B., Kraft, P. and Freedman, M.L. (2014) Expression QTL-based analyses reveal candidate causal genes andlociacrossfivetumor types. Hum.Mol.Genet.,23,5294-5302.
-
(2014)
Hum.Mol.Genet.
, vol.23
, pp. 5294-5302
-
-
Li, Q.1
Stram, A.2
Chen, C.3
Kar, S.4
Gayther, S.5
Pharoah, P.6
Haiman, C.7
Stranger, B.8
Kraft, P.9
Freedman, M.L.10
-
31
-
-
84921046649
-
Association of prostate cancer risk variants with gene expression in normal and tumor tissue
-
Penney, K.L., Sinnott, J.A., Tyekucheva, S., Gerke, T., Shui, I.M., Kraft, P., Sesso, H.D., Freedman, M.L., Loda, M., Mucci, L.A. et al. (2014) Association of prostate cancer risk variants with gene expression in normal and tumor tissue. Cancer Epidemiol. Biomarkers Prev., 24, 255-262.
-
(2014)
Cancer Epidemiol. Biomarkers Prev.
, vol.24
, pp. 255-262
-
-
Penney, K.L.1
Sinnott, J.A.2
Tyekucheva, S.3
Gerke, T.4
Shui, I.M.5
Kraft, P.6
Sesso, H.D.7
Freedman, M.L.8
Loda, M.9
Mucci, L.A.10
-
32
-
-
85028171423
-
Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins
-
Buil, A., Brown, A.A., Lappalainen, T., Vinuela, A., Davies, M.N., Zheng, H.F., Richards, J.B., Glass, D., Small, K.S., Durbin, R. et al. (2014) Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins. Nat. Genet., 47, 88-91.
-
(2014)
Nat. Genet.
, vol.47
, pp. 88-91
-
-
Buil, A.1
Brown, A.A.2
Lappalainen, T.3
Vinuela, A.4
Davies, M.N.5
Zheng, H.F.6
Richards, J.B.7
Glass, D.8
Small, K.S.9
Durbin, R.10
-
33
-
-
84899627083
-
Genetic interactions affecting human gene expression identified by variance association mapping
-
Brown, A.A., Buil, A., Vinuela, A., Lappalainen, T., Zheng, H.F., Richards, J.B., Small, K.S., Spector, T.D., Dermitzakis, E.T. and Durbin, R. (2014) Genetic interactions affecting human gene expression identified by variance association mapping. Elife, 3, e01381.
-
(2014)
Elife
, vol.3
, pp. e01381
-
-
Brown, A.A.1
Buil, A.2
Vinuela, A.3
Lappalainen, T.4
Zheng, H.F.5
Richards, J.B.6
Small, K.S.7
Spector, T.D.8
Dermitzakis, E.T.9
Durbin, R.10
-
34
-
-
78049502208
-
Tubulin tyrosine ligase like 12 links to prostate cancer through tubulin posttranslational modification and chromosome ploidy
-
Wasylyk, C., Zambrano, A., Zhao, C., Brants, J., Abecassis, J., Schalken, J.A., Rogatsch, H., Schaefer, G., Pycha, A., Klocker, H. et al. (2010) Tubulin tyrosine ligase like 12 links to prostate cancer through tubulin posttranslational modification and chromosome ploidy. Int. J. Cancer, 127, 2542-2553.
-
(2010)
Int. J. Cancer
, vol.127
, pp. 2542-2553
-
-
Wasylyk, C.1
Zambrano, A.2
Zhao, C.3
Brants, J.4
Abecassis, J.5
Schalken, J.A.6
Rogatsch, H.7
Schaefer, G.8
Pycha, A.9
Klocker, H.10
-
35
-
-
80053149973
-
Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association
-
Wood, A.R., Hernandez, D.G., Nalls, M.A., Yaghootkar, H., Gibbs, J.R., Harries, L.W., Chong, S., Moore, M., Weedon, M.N., Guralnik, J.M. et al. (2011) Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association. Hum. Mol. Genet., 20, 4082-4092.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 4082-4092
-
-
Wood, A.R.1
Hernandez, D.G.2
Nalls, M.A.3
Yaghootkar, H.4
Gibbs, J.R.5
Harries, L.W.6
Chong, S.7
Moore, M.8
Weedon, M.N.9
Guralnik, J.M.10
-
36
-
-
84908046605
-
Another explanation for apparent epistasis
-
Wood, A.R., Tuke, M.A., Nalls, M.A., Hernandez, D.G., Bandinelli, S., Singleton, A.B., Melzer, D., Ferrucci, L., Frayling, T.M. andWeedon, M.N. (2014) Another explanation for apparent epistasis. Nature, 514, E3-E5.
-
(2014)
Nature
, vol.514
, pp. E3-E5
-
-
Wood, A.R.1
Tuke, M.A.2
Nalls, M.A.3
Hernandez, D.G.4
Bandinelli, S.5
Singleton, A.B.6
Melzer, D.7
Ferrucci, L.8
Frayling, T.M.9
Weedon, M.N.10
-
37
-
-
84901741339
-
Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer
-
Saunders, E.J., Dadaev, T., Leongamornlert, D.A., Jugurnauth-Little, S., Tymrakiewicz, M.,Wiklund, F., Al Olama, A.A., Benlloch, S., Neal, D.E., Hamdy, F.C. et al. (2014) Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer. PLoS Genet., 10, e1004129.
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004129
-
-
Saunders, E.J.1
Dadaev, T.2
Leongamornlert, D.A.3
Jugurnauth-Little, S.4
Tymrakiewicz, M.5
Wiklund, F.6
Al Olama, A.A.7
Benlloch, S.8
Neal, D.E.9
Hamdy, F.C.10
-
38
-
-
84904849365
-
Consortium launches genotyping effort
-
Saunders, E.J., Dadaev, T., Leongamornlert, D.A., Jugurnauth-Little, S., Tymrakiewicz, M.,Wiklund, F., Al Olama, A.A., Benlloch, S., Neal, D.E., Hamdy, F.C. et al.(2013) Consortium launches genotyping effort. Cancer Discov., 3, 1321-1322.
-
(2013)
Cancer Discov.
, vol.3
, pp. 1321-1322
-
-
Saunders, E.J.1
Dadaev, T.2
Leongamornlert, D.A.3
Jugurnauth-Little, S.4
Tymrakiewicz, M.5
Wiklund, F.6
Al Olama, A.A.7
Benlloch, S.8
Neal, D.E.9
Hamdy, F.C.10
-
39
-
-
84892746185
-
Quantifying missing heritability at known GWAS loci
-
Gusev, A., Bhatia, G., Zaitlen, N., Vilhjalmsson, B.J., Diogo, D., Stahl, E.A., Gregersen, P.K.,Worthington, J., Klareskog, L., Raychaudhuri, S. et al. (2013) Quantifying missing heritability at known GWAS loci. PLoS Genet., 9, e1003993.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003993
-
-
Gusev, A.1
Bhatia, G.2
Zaitlen, N.3
Vilhjalmsson, B.J.4
Diogo, D.5
Stahl, E.A.6
Gregersen, P.K.7
Worthington, J.8
Klareskog, L.9
Raychaudhuri, S.10
-
40
-
-
54049139306
-
Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium
-
Kote-Jarai, Z., Easton, D.F., Stanford, J.L., Ostrander, E.A., Schleutker, J., Ingles, S.A., Schaid, D., Thibodeau, S., Dork, T., Neal, D. et al. (2008) Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium. Cancer Epidemiol. Biomarkers Prev., 17, 2052-2061.
-
(2008)
Cancer Epidemiol. Biomarkers Prev.
, vol.17
, pp. 2052-2061
-
-
Kote-Jarai, Z.1
Easton, D.F.2
Stanford, J.L.3
Ostrander, E.A.4
Schleutker, J.5
Ingles, S.A.6
Schaid, D.7
Thibodeau, S.8
Dork, T.9
Neal, D.10
-
41
-
-
67651222400
-
A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
-
Howie, B.N., Donnelly, P. and Marchini, J. (2009) A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet., 5, e1000529.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000529
-
-
Howie, B.N.1
Donnelly, P.2
Marchini, J.3
-
42
-
-
34347344976
-
A newmultipoint method for genome-wide association studies by imputation of genotypes
-
Marchini, J., Howie, B., Myers, S., McVean, G. and Donnelly, P. (2007) A newmultipoint method for genome-wide association studies by imputation of genotypes. Nat. Genet., 39, 906-913.
-
(2007)
Nat. Genet.
, vol.39
, pp. 906-913
-
-
Marchini, J.1
Howie, B.2
Myers, S.3
McVean, G.4
Donnelly, P.5
-
43
-
-
77955894071
-
METAL: fast and efficient meta-analysis of genomewide association scans
-
Willer, C.J., Li, Y. and Abecasis, G.R. (2010) METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics, 26, 2190-2191.
-
(2010)
Bioinformatics
, vol.26
, pp. 2190-2191
-
-
Willer, C.J.1
Li, Y.2
Abecasis, G.R.3
-
44
-
-
0036155283
-
Score tests for association between traits and haplotypes when linkage phase is ambiguous
-
Schaid, D.J., Rowland, C.M., Tines, D.E., Jacobson, R.M. and Poland, G.A. (2002) Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am. J. Hum. Genet., 70, 425-434.
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 425-434
-
-
Schaid, D.J.1
Rowland, C.M.2
Tines, D.E.3
Jacobson, R.M.4
Poland, G.A.5
-
45
-
-
77955297273
-
Fine scale mapping of the breast cancer 16q12 locus
-
Udler, M.S., Ahmed, S., Healey, C.S., Meyer, K., Struewing, J., Maranian, M., Kwon, E.M., Zhang, J., Tyrer, J., Karlins, E. et al. (2010) Fine scale mapping of the breast cancer 16q12 locus. Hum. Mol. Genet., 19, 2507-2515.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 2507-2515
-
-
Udler, M.S.1
Ahmed, S.2
Healey, C.S.3
Meyer, K.4
Struewing, J.5
Maranian, M.6
Kwon, E.M.7
Zhang, J.8
Tyrer, J.9
Karlins, E.10
-
46
-
-
75649120390
-
Prostate cancer segregation analyses using 4390 families from UK and Australian populationbased studies
-
MacInnis, R.J., Antoniou, A.C., Eeles, R.A., Severi, G., Guy, M., McGuffog, L., Hall, A.L., O'Brien, L.T.,Wilkinson, R.A., Dearnaley, D.P. et al. (2010) Prostate cancer segregation analyses using 4390 families from UK and Australian populationbased studies. Genet. Epidemiol., 34, 42-50.
-
(2010)
Genet. Epidemiol.
, vol.34
, pp. 42-50
-
-
MacInnis, R.J.1
Antoniou, A.C.2
Eeles, R.A.3
Severi, G.4
Guy, M.5
McGuffog, L.6
Hall, A.L.7
O'Brien, L.T.8
Wilkinson, R.A.9
Dearnaley, D.P.10
-
47
-
-
80051813565
-
A risk prediction algorithm based on family history and common genetic variants: application to prostate cancer with potential clinical impact
-
Macinnis, R.J., Antoniou, A.C., Eeles, R.A., Severi, G., Al Olama, A.A., McGuffog, L., Kote-Jarai, Z., Guy, M., O'Brien, L.T., Hall, A.L. et al. (2011) A risk prediction algorithm based on family history and common genetic variants: application to prostate cancer with potential clinical impact. Genet. Epidemiol., 35, 549-556.
-
(2011)
Genet. Epidemiol.
, vol.35
, pp. 549-556
-
-
Macinnis, R.J.1
Antoniou, A.C.2
Eeles, R.A.3
Severi, G.4
Al Olama, A.A.5
McGuffog, L.6
Kote-Jarai, Z.7
Guy, M.8
O'Brien, L.T.9
Hall, A.L.10
-
50
-
-
84865564453
-
ggbio: an R package for extending the grammar of graphics for genomic data
-
Yin, T., Cook, D. and Lawrence, M. (2012) ggbio: an R package for extending the grammar of graphics for genomic data. Genome Biol., 13, R77.
-
(2012)
Genome Biol.
, vol.13
, pp. R77
-
-
Yin, T.1
Cook, D.2
Lawrence, M.3
-
51
-
-
84914811758
-
-
R Studio, I. (2014) Web Application Framework for R, http:// www.bioconductor.org/packages/2.11/bioc/html/ggbio.html.
-
(2014)
Web Application Framework for R
-
-
-
52
-
-
84865755978
-
The accessible chromatin landscape of the human genome
-
Thurman, R.E., Rynes, E., Humbert, R., Vierstra, J., Maurano, M.T., Haugen, E., Sheffield, N.C., Stergachis, A.B., Wang, H., Vernot, B. et al. (2012) The accessible chromatin landscape of the human genome. Nature, 489, 75-82.
-
(2012)
Nature
, vol.489
, pp. 75-82
-
-
Thurman, R.E.1
Rynes, E.2
Humbert, R.3
Vierstra, J.4
Maurano, M.T.5
Haugen, E.6
Sheffield, N.C.7
Stergachis, A.B.8
Wang, H.9
Vernot, B.10
-
53
-
-
84867562866
-
FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs
-
Coetzee, S.G., Rhie, S.K., Berman, B.P., Coetzee, G.A. and Noushmehr, H. (2012) FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs. Nucleic Acids Res., 40, e139.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. e139
-
-
Coetzee, S.G.1
Rhie, S.K.2
Berman, B.P.3
Coetzee, G.A.4
Noushmehr, H.5
-
54
-
-
79959198166
-
Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA
-
Wang, D., Garcia-Bassets, I., Benner, C., Li,W., Su, X., Zhou, Y., Qiu, J., Liu, W., Kaikkonen, M.U., Ohgi, K.A. et al. (2011) Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA. Nature, 474, 390-394.
-
(2011)
Nature
, vol.474
, pp. 390-394
-
-
Wang, D.1
Garcia-Bassets, I.2
Benner, C.3
Li, W.4
Su, X.5
Zhou, Y.6
Qiu, J.7
Liu, W.8
Kaikkonen, M.U.9
Ohgi, K.A.10
-
55
-
-
84863072810
-
Integration of regulatory networks by NKX3-1 promotes androgen-dependent prostate cancer survival
-
Tan, P.Y., Chang, C.W., Chng, K.R., Wansa, K.D., Sung, W.K. and Cheung, E. (2012) Integration of regulatory networks by NKX3-1 promotes androgen-dependent prostate cancer survival. Mol. Cell. Biol., 32, 399-414.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 399-414
-
-
Tan, P.Y.1
Chang, C.W.2
Chng, K.R.3
Wansa, K.D.4
Sung, W.K.5
Cheung, E.6
-
56
-
-
83255192190
-
Dynamic nucleosomedepleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells
-
Andreu-Vieyra, C., Lai, J., Berman, B.P., Frenkel, B., Jia, L., Jones, P.A. and Coetzee, G.A. (2011) Dynamic nucleosomedepleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells. Mol. Cell. Biol., 31, 4648-4662.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 4648-4662
-
-
Andreu-Vieyra, C.1
Lai, J.2
Berman, B.P.3
Frenkel, B.4
Jia, L.5
Jones, P.A.6
Coetzee, G.A.7
-
57
-
-
84872391385
-
The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man
-
Sharma, N.L., Massie, C.E., Ramos-Montoya, A., Zecchini, V., Scott, H.E., Lamb, A.D., MacArthur, S., Stark, R., Warren, A.Y., Mills, I.G. et al. (2013) The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man. Cancer Cell, 23, 35-47.
-
(2013)
Cancer Cell
, vol.23
, pp. 35-47
-
-
Sharma, N.L.1
Massie, C.E.2
Ramos-Montoya, A.3
Zecchini, V.4
Scott, H.E.5
Lamb, A.D.6
MacArthur, S.7
Stark, R.8
Warren, A.Y.9
Mills, I.G.10
-
58
-
-
84865138690
-
miRcode: a map of putative microRNA target sites in the long non-coding transcriptome
-
Jeggari, A., Marks, D.S. and Larsson, E. (2012) miRcode: a map of putative microRNA target sites in the long non-coding transcriptome. Bioinformatics, 28, 2062-2063.
-
(2012)
Bioinformatics
, vol.28
, pp. 2062-2063
-
-
Jeggari, A.1
Marks, D.S.2
Larsson, E.3
-
59
-
-
84865852567
-
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
-
Wang, J., Zhuang, J., Iyer, S., Lin, X., Whitfield, T.W., Greven, M.C., Pierce, B.G., Dong, X., Kundaje, A., Cheng, Y. et al. (2012) Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors. Genome Res., 22, 1798-1812.
-
(2012)
Genome Res.
, vol.22
, pp. 1798-1812
-
-
Wang, J.1
Zhuang, J.2
Iyer, S.3
Lin, X.4
Whitfield, T.W.5
Greven, M.C.6
Pierce, B.G.7
Dong, X.8
Kundaje, A.9
Cheng, Y.10
-
60
-
-
84861153094
-
Matrix eQTL: ultra fast eQTL analysis via large matrix operations
-
Shabalin, A.A. (2012) Matrix eQTL: ultra fast eQTL analysis via large matrix operations. Bioinformatics, 28, 1353-1358.
-
(2012)
Bioinformatics
, vol.28
, pp. 1353-1358
-
-
Shabalin, A.A.1
-
61
-
-
84861734626
-
Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses
-
Stegle, O., Parts, L., Piipari, M., Winn, J. and Durbin, R. (2012) Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses. Nat. Protoc., 7, 500-507.
-
(2012)
Nat. Protoc.
, vol.7
, pp. 500-507
-
-
Stegle, O.1
Parts, L.2
Piipari, M.3
Winn, J.4
Durbin, R.5
-
62
-
-
69649109364
-
Circos: An information aesthetic for comparative genomics
-
Krzywinski, M.I., Schein, J.E., Birol, I., Connors, J., Gascoyne, R., Horsman, D., Jones, S.J. and Marra, M.A. (2009) Circos: An information aesthetic for comparative genomics. Genome Res., 19, 1639-1645.
-
(2009)
Genome Res.
, vol.19
, pp. 1639-1645
-
-
Krzywinski, M.I.1
Schein, J.E.2
Birol, I.3
Connors, J.4
Gascoyne, R.5
Horsman, D.6
Jones, S.J.7
Marra, M.A.8
|