Reduced miR-512 and the elevated expression of its targets cFLIP and MCL1 localize to neurons with hyperphosphorylated tau protein in Alzheimer disease

Applied Immunohistochemistry and Molecular Morphology

Volumn 23, Issue 9, 2015, Pages 615-623

  Mezache, Louisa ^a   Mikhail, Madison ^a   Garofalo, Michela ^b   Nuovo, Gerard J ^a,b  

^a Phylogeny Inc   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

cFLIP; Hyperphosphorylated; MCL1; microRNA; Tau

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 4; CASPASE 8; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEIN; FLICE INHIBITORY PROTEIN; MICRORNA; MICRORNA 512; MITOGEN ACTIVATED PROTEIN KINASE P38; MYC PROTEIN; NEUROTROPHIN 3 RECEPTOR; PROTEIN KINASE B; PROTEIN MCL 1; PYRUVATE DEHYDROGENASE; RAS PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TAU PROTEIN; UNCLASSIFIED DRUG; AIFM1 PROTEIN, HUMAN; AMYLOID BETA PROTEIN; APAF1 PROTEIN, HUMAN; APOPTOSIS INDUCING FACTOR; CASP4 PROTEIN, HUMAN; INITIATOR CASPASE; MAPT PROTEIN, HUMAN; MCL1 PROTEIN, HUMAN; MCM2 PROTEIN, HUMAN; MINICHROMOSOME MAINTENANCE PROTEIN 2; MIRN512 MICRORNA, HUMAN;

AGED; ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; AUTOPSY; CONTROLLED STUDY; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NERVE CELL; NEURAL STEM CELL; NEUROFIBRILLARY TANGLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; VERY ELDERLY; WHITE MATTER; BRAIN; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TUNEL ASSAY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; APOPTOSIS; APOPTOSIS INDUCING FACTOR; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BRAIN; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 3; CASPASE 8; CASPASES, INITIATOR; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; MICRORNAS; MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 2; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; NEURONS; PHOSPHORYLATION; TAU PROTEINS;

EID: 84943750712     PISSN: 15412016     EISSN: 15334058     Source Type: Journal    
DOI: 10.1097/PAI.0000000000000147     Document Type: Article

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