Lymphoblastoid cell lines reveal associations of adult DNA methylation with childhood and current adversity that are distinct from whole blood associations

International Journal of Epidemiology

Volumn 44, Issue 4, 2015, Pages 1331-1340

  Suderman, Matthew ^a   Pappas, Jane J ^b,c   Borghol, Nada ^d   Buxton, Jessica L ^e   McArdle, Wendy L ^a   Ring, Susan M ^a   Hertzman, Clyde ^f   Power, Chris ^g   Szyf, Moshe ^c,h   Pembrey, Marcus ^g  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d LEBANESE UNIVERSITY   (Lebanon)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^g UNIVERSITY COLLEGE LONDON   (United Kingdom)

^h MCGILL UNIVERSITY   (Canada)

Author keywords

1958 british birth cohort; Childhood abuse; DNA methylation; Early life adversity; Epigenetics; Lymphoblastoid cell lines; Prenatal tobacco; Social position

Indexed keywords

CD19 ANTIGEN;

BIRTH RATE; BLOOD; CHILD HEALTH; COHORT ANALYSIS; DNA; EPIDEMIOLOGY; GENETICS; METHYLATION; POLLUTION EXPOSURE; SOCIOECONOMIC STATUS; TOBACCO; VIRUS;

ADULT; ARTICLE; BLOOD; CHILD ABUSE; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ECONOMIC ASPECT; EPIGENETICS; EPSTEIN BARR VIRUS; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; MALE; PILOT STUDY; PRENATAL EXPOSURE; PRIORITY JOURNAL; TOBACCO; B LYMPHOCYTE; CELL LINE; CHILD ABUSE SURVIVOR; CYTOLOGY; GENETIC EPIGENESIS; MIDDLE AGED; SOCIAL CLASS; TOBACCO USE;

UNITED KINGDOM;

HUMAN HERPESVIRUS 4; NICOTIANA TABACUM;

ADULT; ADULT SURVIVORS OF CHILD ABUSE; B-LYMPHOCYTES; CELL LINE; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; EPIGENOMICS; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS; SOCIAL CLASS; TOBACCO USE;

EID: 84943745763     PISSN: 03005771     EISSN: 14643685     Source Type: Journal    
DOI: 10.1093/ije/dyv168     Document Type: Article

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