Inhibiting amyloid β-protein assembly: Size-activity relationships among grape seed-derived polyphenols

Journal of Neurochemistry

Volumn 135, Issue 2, 2015, Pages 416-430

  Hayden, Eric Y ^a   Yamin, Ghiam ^a,b,e   Beroukhim, Shiela ^a   Chen, Benson ^a   Kibalchenko, Mikhail ^a   Jiang, Lin ^a   Ho, Lap ^c   Wang, Jun ^c,d   Pasinetti, Giulio M ^c,d   Teplow, David B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; amyloid protein (A ); grape seeds; inhibitors; oligomers; polyphenols

Indexed keywords

AMYLOID BETA PROTEIN; DIMER; GRAPE SEED EXTRACT; MONOMER; OLIGOMER; POLYPHENOL; CROSS LINKING REAGENT; FLUORESCENT DYE; THIAZOLE DERIVATIVE; THIOFLAVINE;

ARTICLE; CIRCULAR DICHROISM; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; ELECTRON MICROSCOPY; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS CONCENTRATION; MOLAR CONCENTRATION; MOLECULAR MODEL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; X RAY CRYSTALLOGRAPHY; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; MOLECULAR WEIGHT; MOUSE; NEUROFIBRILLARY TANGLE; PATHOLOGY; PLANT SEED; STRUCTURE ACTIVITY RELATION; ULTRASTRUCTURE; VITIS;

AMYLOID BETA-PEPTIDES; ANIMALS; CIRCULAR DICHROISM; CROSS-LINKING REAGENTS; FLUORESCENT DYES; MICE; MODELS, MOLECULAR; MOLECULAR WEIGHT; NEUROFIBRILLARY TANGLES; POLYPHENOLS; PROTEIN CONFORMATION; SEEDS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; VITIS;

EID: 84943587930     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13270     Document Type: Article

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