The Intolerance of Regulatory Sequence to Genetic Variation Predicts Gene Dosage Sensitivity

PLoS Genetics

Volumn 11, Issue 9, 2015, Pages

  Petrovski, Slavé ^a,b,c   Gussow, Ayal B ^a,b,d   Wang, Quanli ^a,b   Halvorsen, Matt ^a,b   Han, Yujun ^b   Weir, William H ^b   Allen, Andrew S ^b   Goldstein, David B ^a,b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; GENE DOSAGE; GENE EXPRESSION; GENE IDENTIFICATION; GENE MUTATION; GENE SEQUENCE; GENETIC CONSERVATION; GENETIC VARIABILITY; HAPLOINSUFFICIENCY; MOLECULAR PHYLOGENY; PURIFYING SELECTION; REGULATORY SEQUENCE; GENETIC VARIATION; GENETICS; HUMAN; MENTAL DISEASE; MUTATION; NEUROLOGIC DISEASE;

DNA COPY NUMBER VARIATIONS; GENE DOSAGE; GENETIC VARIATION; HAPLOINSUFFICIENCY; HUMANS; MENTAL DISORDERS; MUTATION; NERVOUS SYSTEM DISEASES; REGULATORY SEQUENCES, NUCLEIC ACID;

EID: 84943536668     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005492     Document Type: Article

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