Endophytic actinobacteria of medicinal plants: Diversity and bioactivity

Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology

Volumn 108, Issue 2, 2015, Pages 267-289

  Golinska, Patrycja ^a   Wypij, Magdalena ^a   Agarkar, Gauravi ^b   Rathod, Dnyaneshwar ^a,b   Dahm, Hanna ^a   Rai, Mahendra ^b  

^a NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^b SANT GADGE BABA AMRAVATI UNIVERSITY   (India)

Author keywords

Actinobacteria; Antimicrobial activity; Bioactive compounds; Endophytes; Medicinal plants

Indexed keywords

1 HYDROXY BETA CARBOLINE; 1H INDOLE 3 CARBOXALDEHYDE; 5,7 DIMETHOXY 4 4 METHOXYLPHENYL COUMARIN; 5,7 DIMETHOXY 4 4 METHOXYLPHENYLCOUMARIN; 5,7 DIMETHOXY 4 PHENYLCOUMARIN; 6 ALKALYSALICYCLIC ACID; 6 PRENYLINDOLE; ANICEMYCIN; CEDARMYCIN; CELASTRAMYCIN A; CELASTRAMYCIN B; CLETHRAMYCIN; CORONAMYCIN; DACTINOMYCIN; FISTUPYRONE; KAKADUMYCIN A; LUMICHROME; LUPINACIDIN A; LUPINACIDIN B; MUNUMBICIN A; MUNUMBICIN B; MUNUMBICIN C; MUNUMBICIN D; MUNUMBICIN E 4; MUNUMBICIN E 5; NATURAL PRODUCT; PERLOLYRINE; PTEROCIDIN; SAADAMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACTINOBACTERIA; ACTINOMADURA; ACTINOPOLYSPORA; AMYCOLATOPSIS; ANTIDIABETIC ACTIVITY; ANTIMALARIAL ACTIVITY; ANTIVIRAL ACTIVITY; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIUM; BACTERIUM COLONY; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATION; BIOLOGICAL ACTIVITY; CYTOTOXICITY; ENDOPHYTE; GENE CLUSTER; KIBDELOSPORANGIUM; KITASATOSPORIA; LEIFSONIA; MEDICINAL PLANT; MICROMONOSPORA; NOCARDIA; NONHUMAN; PLANT GROWTH; PRIORITY JOURNAL; PSEUDONOCARDIA; REVIEW; SPECIES DIVERSITY; SPECIES HABITAT; STREPTOMYCES; BIODIVERSITY; CLASSIFICATION; ISOLATION AND PURIFICATION; MICROBIOLOGY; PHYSIOLOGY; SYMBIOSIS;

ACTINOBACTERIA; BIODIVERSITY; ENDOPHYTES; PLANTS, MEDICINAL; SYMBIOSIS;

EID: 84943454066     PISSN: 00036072     EISSN: 15729699     Source Type: Journal    
DOI: 10.1007/s10482-015-0502-7     Document Type: Review

References (119)

1. Akshatha VJ, Nalini MS, D’Souza C, Prakash HS (2014) Streptomycete endophytes from anti-diabetic medicinal plants of the Western Ghats inhibit alpha-amylase and promote glucose uptake. Lett Appl Microbiol 58:433–439
2. Bascom-Slack CA, Ma C, Moore E, Babbs B, Fenn K, Greene JS, Hann BD, Keehner J, Kelley-Swift EG, Kembaiyan V, Lee SJ, Li P, Light DY, Lin EH, Schorn MA, Vekhter D, Boulanger LA, Hess WM, Vargas PN, Strobel GA, Strobel SA (2009) Multiple, novel biologically active endophytic actinomycetes isolated from upper Amazonian rainforests. Microbiol Ecol 58:374–383
3. Bentley SD, Chater KF, Cerdano-Tarraga AM, Challis GL, Thomson NR, James KD et al (2002) Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 417:141–147
4. Berdy J (2012) Thoughts and facts about antibiotics: where we are now and where we are heading. J Antibiot 65:385–395
5. Bian G-K, Qin S, Yuan B, Zhang Y-J, Xing K, Ju X-J, Li W-J, Jiang J-H (2012a) Streptomyces phytohabitans sp. nov. a novel endophytic actinomycete isolated from medicinal plant Curcuma phaeocaulis. Ant van Leeuw 102:289–296
6. Bian G-K, Feng ZZ, Qin S, Xing K, Wang Z, Cao CL, Liu CH, Dai CC, Jiang J-H (2012b) Kineococcus endophytica sp. nov. a novel endophytic actinomycete isolated from a coastal halophyte in Jiangsu. Ant van Leeuw 102(4):621–628
7. Cao L, Qiu Z, You J, Tan H, Zhou S (2005) Isolation and characterization of endophytic Streptomyces antagonists of Fusarium wilt pathogen from surface sterilized banana roots. FEMS Microbiol Lett 247:147–152
8. Caruso M, Colombo AL, Fedeli L, Pavesi A, Quaroni S, Saracchi M et al (2000) Isolation of endophytic fungi and actinomycetes taxane producers. Ann Microbiol 50:3–13
9. Castillo U, Strobel G, Ford E, Hess W, Porter H, Jensen J et al (2002) Munumbicins, wide- spectrum antibiotics produced by Streptomyces NRRL 30562, endophytic on Kennedia nigriscans. Microbiol 148:2675–2685
10. Castillo U, Harper J, Strobel G, Sears J, Alesi K, Ford E et al (2003) Kakadumycins, novel anti biotics from Streptomyces sp. NRRL 30566, an endophyte of Grevillea pteridifolia. FEMS Microbiol Lett 224(2):183–190
11. Castillo UF, Strobel GA, Mullenberg K, Condron MM, Teplow DB, Folgiano V et al (2006) Munumbicins E-4 and E-5: novel broad-spectrum antibiotics from Streptomyces NRRL 3052. FEMS Microbiol Lett 255:296–300
12. Chen H-H, Qin S, Li J, Zhang Y-Q, Xu L-H, Jiang C-L, Kim C-J, Li W-J (2009) Pseudonocardia endophytica sp. nov. isolated from the pharmaceutical plant Lobelia clavata. Int J Syst Evolut Microbiol 59:559–563
13. Chen M, Zhang L, Zhang X (2011) Isolation and inoculation of endophytic actinomycetes in root nodules of Elaeagnus angustifolia. Mod Appl Sci 5(2):p264
14. Chithra S, Jasima B, Sachidanandanb P, Jyothisa M, Radhakrishnana EK (2014) Piperine production by endophytic fungus Colletotrichum gloeosporioides isolated from Piper nigrum. S Phytomed 21:534–540
15. Conti R, Cunha IGB, Siqueira VM, Souza-Motta CM, Amorim ELC, Araujo JM (2012) Endophytic microorganisms from leaves of Spermacoce verticillata (L.): diversity and antimicrobial activity. J Appl Pharm Sci 2(12):17–22
16. Crawford DL, Lynch JM, Whipps JM, Ousley MA (1993) Isolation and characterization of actinomycete antagonists of a fungal root pathogen. Appl Environ Microbiol 59(11):3889–3905
17. De Bary A (1866) Morphologie und Physiologie der Pilze, Flechten, und Myxomyceten. Hofmeister’s handbook of physiological Botany. W. Engelmann, Leipzig
18. Dochhil H, Dkhar MS, Barman D (2013) Seed germination enhancing activity of endophytic Streptomyces isolated from indigenous ethno-medicinal plant Centella asiatica. Int J Pharm Biol Sci 4(1):256–262
19. Doroghazi JR, Metcalf WW (2013) Comparative genomics of actinomycetes with a focus on natural product biosynthetic genes. BMC Genomic 14:611
20. Du H, Su J, Yu L, Zhang Y (2013a) Isolation and physiological characteristics of endophytic actinobacteria from medicinal plants. Wei Sheng Wu Xue Bao 53(1):15–23
21. Du HJ, Zhang YQ, Liu HY, Su J, Wei YZ, Ma BP et al (2013b) Allonocardiopsis opalescens gen. nov. sp. nov. a new member of the suborder Streptosporangineae, from the surface-sterilized fruit of a medicinal plant. Int J Syst Evol Microbiol 63:900–904
22. El-Gendy MMA, EL-Bondkly AMA (2010) Production and genetic improvement of a novel antimycotic agent, saadamycin, against dermatophytes and other clinical fungi from endophytic Streptomyces sp. Hedaya48. J Ind Microbiol Biotechnol 37:831–841
23. El-Shatoury S, Abdulla H, El-Karaaly O, El-Kazzaz W, Dewedar A (2006) Bioactivities of endophytic actinomycetes from selected medicinal plants in the world heritage site of Saint Katherine. Egypt Int J Bot 2(3):307–312
24. El-Shatoury S, El-Kraly O, El-Kazzaz W, Dewedar A (2009) Antimicrobial activities of Actinomycetes inhabiting Achillea fragrantissima (Family: Compositae). Egypt J Nat Toxins 6(2):1–15
25. El-Shatoury SA, El-Kraly OA, Trujillo ME, El-Kazzaz WM, El- Din E-SG, Dewedar A (2013) Generic and functional diversity in endophytic actinomycetes from wild Compositae plant species at South Sinai—Egypt. Res Microbiol 164:761–769
26. El-Tarabily KA (2003) An endophytic chitinase-producing isolate of Actinoplanes missouriensis, with potential for biological control of root rot of lupine caused by Plectosporium tabacinum. Aust J Bot 51:257–266
27. El-Tarabily KA, Sivasithamparam K (2006) Nonstreptomycete actinomycetes as biocontrol agents of soil-borne fungal plant pathogens and as plant growth promoters. Soil Biol Biochem 38:1505–1520
28. El-Tarabily KA, Hardy GEStJ, Sivasithamparam K (2010) Performance of three endophytic actinomycetes in relation to plant growth promotion and biological control of Pythium aphanidermatum, a pathogen of cucumber under commercial field production conditions in the United Arab Emirates. Eur J Plant Pathol 128:527–539
29. Eyberger AL, Dondapati R, Porter JR (2006) Endophyte fungal isolates from Podophyllum peltatum produce podophyllotoxin. J Nat Prod 69:1121–1124
30. Ezra D, Castillo UF, Strobel GA, Hess WM, Porter H, Jensen JB, Condron MAM, Teplow DB, Sears J, Maranta M, Hunter M, Weber B, Yaver D (2004) Coronamycins, peptide antibiotics produced by a verticillate Streptomyces sp. (MSU-2110) endophytic on Monstera sp. Microbiology 150:785–793
31. Fiedler H, Bruntner C, Riedlinger J, Bull AT, Knutsen G, Goodfellow M et al (2008) Proximicin A, B and C, novel aminofuran antibiotic and anticancer compounds isolated from marine strains of the actinomycetes Verrucosispora. J Antibiot 61:158–163
32. Gaiero JR, McCall CA, Thompson KA, Day NJ, Best AS, Dunfield KE (2013) inside the root microbiome: bacterial root endophytes and plant growth promotion. Am J Bot 100:1738–1750
33. Gangwar M, Dogra S, Sharma N (2011) Antagonistic bioactivity of endophytic actinomycetes isolated from medicinal plants. J Advanced Lab Res Biol 2(4):154–157
34. Gangwar M, Dogra S, Gupta UP, Kharwar RN (2014) Diversity and biopotential of endophytic actinomycetes from three medicinal plants in India. African J Microbiol Res 8(2):184–191
35. Goodfellow M, Fiedler HP (2010) A guide to successful bioprospecting: informed by actinobacterial systematics. Ant van Leeuw 98:119–142
36. Goodfellow M, Kämpfer P, Busse H-J, Trujillo ME, Suzuki K-I, Ludwig W, Whitman WB (2012) Bergey’s manual of systematic bacteriology, 2nd edn, vol 5 The Actinobacteria, Part A, Springer, New York
37. Hallmann J (2001) Plant interactions with endophytic bacteria. In: Jeger MJ, Spence NJ (eds) Biotic interactions in plantpathogen association. CAB International, Wallingford, pp 87–119
38. Hallmann J, Berg G, Schulz B (2006) Isolation procedures for endophytic microorganisms. In: Schulz B, Boyle C, Sieber TN (eds) Soil biology, vol 9. Microbial Root EndophytesSpringer-Verlag, Berlin Heidelberg, pp 299–319
39. Hasegawa T, Lechevalier MP, Lechevalier HA (1978) New genus of the Actinomycetales: Actinosynnema gen. nov. Int J Syst Bacteriol 28:304–310
40. Hasegawa S, Meguro A, Shimizu M, Nishimura T, Kunoh H (2006) Endophytic actinomycetes and their interactions with host plants. Actinomycetologica 20:72–81
41. Hayakawa M, Nonomura H (1987) Efficacy of artificial humic acid is a selective nutrient in HV agar used for the isolation of actinomycetes. J Ferment Technol 65:609–616
42. Hou BC, Wang ET, Li Y, Jia RZ, Chen WF, Man CX et al (2009) Rhizobial resource associated with epidemic legumes in Tibet. Microb Ecol 57:69–81
43. Igarashi Y (2004) Screening of novel bioactive compounds from plant-associated actinomycetes. Actinomycetolog 18:63–66
44. Igarashi Y, Iida T, Sasaki T, Saito N, Yoshida R, Furumai T (2002) Isolation of actinomycetes from live plants and evaluation of antiphytopathogenic activity of their metabolites. Actinomycetolog 16:9–13
45. Igarashi Y, Miura S, Fujita T, Furumai T (2006) Pterocidin, a cytotoxic compound from the endophytic Streptomyces hygroscopicus. J Antibiot 59(3):193–195
46. Igarashi Y, Trujillo ME, Martinez-Molina E, Yanase S, Miyanaga S, Obata T et al (2007) Antitumor anthraquinones from an endophytic actinomycete Micromonospora lupini sp. nov. Bioorg Med Chem Lett 17:3702–3705
47. Igarashi Y, Mogi T, Yanase S, Miyanaga S, Fujita T, Sakurai H et al (2009) Brartemicin, an inhibitor of tumor cell invasion from the actinomycete Nonomuraea sp. J Nat Prod 72:980–982
48. Ikeda H, Ishikawa J, Hanamoto A, Shinose H, Kikuchi T, Shiba Y et al (2003) Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Nat Biotechnol 21:526–531
49. Ivantiskaya LP, Singal SM, Bibikova MV, Vostrov SN (1978) Direct isolation of Micromonospora on selective media with gentamicin. Antibiot 23:690–692
50. Janso JE, Carter GT (2010) Biosynthetic potential of phylogenetically unique endophytic actinomycetes from tropical plants. Appl Environ Microbiol 76:4377–4386
51. Kafur A, Khan AB (2011) Isolation of endophytic actinomycetes from Catharanthes roseus (L.) G. Don leaves and their antimicrobial activity. Iranian J Biotechnol 9(4):301–306
52. Kim N, Shin JC, KimW Hwang BY, Kim BS, Hong YS et al (2006) Cytotoxic 6-alkylsalicylic acids from the endophytic Streptomyces laceyi. J Antibiot 59(12):797–800
53. Kumar U, Singh A, SivaKumar T (2011) Isolation and screening of endophytic actinomycetes from different parts of Emblica officinalis. Ann Biol Res 2(4):423–434
54. Kumar A, Patil D, Rajamohanan PR, Ahmad A (2013) Isolation, purification and characterization of from endophytic fungus Fusarium oxysporum isolated from Catharanthus roseus. PLoS ONE 8(9):e71805
55. Küster E (1959) Outline of a comparative study of criteria used in characterization of the actinomycetes. Int Bull Bacteriol Nomencl Taxon 9:97–104
56. Küster E, Williams ST (1964) Selection of media for isolation of Streptomycetes. Nature 202:928–929
57. Li J, Zhao GZ, Chen HH, Qin S, Xu LH, Jiang CL (2008) Rhodococcus cercidiphylli sp. nov. a new endophytic actinobacterium isolated from a Cercidiphyllum japonicum leaf. Syst Appl Microbiol 31:108–113
58. Lin ZJ, Lu XM, Zhu TJ, Fang YC, Gu QQ, Zhu W (2008) GPR12 selections of the metabolites from an endophytic Streptomyces sp. asociated with Cistanches deserticola. Arch Pharm Res 31(9):1108–1114
59. Lu C, Shen Y (2003) A new macrolide antibiotic with antitumor activity produced by Streptomyces sp. CS, a commensal microbe of Maytenus hookeri. J Antibiot 56(4):415–418
60. Lu C, Shen Y (2007) A novel ansamycin, naphthomycin k from Streptomyces sp. J Antibiot 60(10):649–653
61. Ludwig W, Klenk HP (2005) Overview: a phylogenetic backbone and taxonomic framework for prokaryotic systematics. In: Brenner DJ, Krieg NR, Staley JT, Garrity GM (eds) Bergey’s manual of systematic bacteriology, 2nd edn, vol 2, the Proteobacteria, part A, introductory essays. Springer, New York pp 49–65
62. Machavariani NG, Ivankova TD, Sineva ON, Terekhova LP (2014) Isolation of endophytic actinomycetes from medicinal plants of the Moscow region, Russia. World Appl Sci J 30(11):1599–1604
63. Minamiyama H, Shimizu M, Kunoh H, Furumai T, Igarashi Y, Onaka H et al (2003) Multiplication of isolate R-5 of Streptomyces galbus on rhododendron leaves and its production of cell wall-degrading enzymes. J Gen Plant Pathol 69:65–70
64. Mincer TJ, Jensen PR, Kauffman CA, Fenical W (2002) Widespread and persistent populations of a major new marine actinomycete taxon in ocean sediments. Appl Environ Microbiol 68:5005–5011
65. Mini Priya R (2012) Endophytic actinomycetes from Indian medicinal plants as antagonists to some phytopathogenic fungi. Open Access Scient Rep 1(4):259
66. Mitchell AM, Strobel GA, Moore E, Robison R, Sears J (2010) Volatile antimicrobials from Muscodor crispans, a novel endophytic fungus. Microbiology 156:270–277
67. Moussa HE, El-Shatoury SA, Wahid OAA, Dewedar A (2011) Characterization of endophytic actinomycetes from wild Egyptian plants as antagonists to some phytopathogenic fungi. Egyptian J Nat Toxins 8(1, 2):32–48
68. Newman DJ, Cragg GM (2007) Natural products as sources of new drugs over the last 25 years. J Nat Prod 70:461–477
69. Nimnoi P, Pongsilp N, Lumyong S (2010) Genetic diversity and community of endophytic actinomycetes within the roots of Aquilaria crassna Pierre ex Lec assessed by actinomycetes- specific PCR and PCR-DGGE of 16S rRNA gene. Biochem Syst Ecol 38(4):595–601
70. Olano C, Mèndez C, Salas JA (2009) Antitumor compounds from actinomycetes from gene clusters to new derivatives by combinatorial synthesis. Nat Prod Rep 26:628–660
71. Oliynyk M, Samborskyy M, Lester JB, Mironenko T, Scott N, Dickens S et al (2007) Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL 23338. Nat Biotechnol 25:447–453
72. O¯ mura S, Ikeda H, Ishikawa J et al (2001) Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites. Proc Natl Acad Sci 98:12215–12220
73. Pandey B, Ghimir P, Agrawal VP (2004) Studies on the antibacterial activity of the actinomycetes isolated from the Khumbu Region of Nepal. International Conference on the Great Himalayas: Climate, Health, Ecology, Management and Conservation, Kathmandu, Organized by Kathmandu University and the Aquatic Ecosystem Health and Management Society, Canada
74. Parrent JL, Peay K, Arnold AE, Comas L, Avis P, Tuininga A (2010) Moving from pattern to process in fungal symbioses: linking functional traits, community ecology, and phylogenetics. New Phytol 185:882–886
75. Passari AK, Mishra VK, Saikia R, Gupta VK, Singh BP (2015) Isolation, abundance and phylogenetic affiliation of endophytic actinomycetes associated with medicinal plants and screening for their in vitro antimicrobial biosynthetic potential. Front Microbiol 6:273. doi:10.3389/fmicb.2015.00273
76. Petrini O, Sieber TN, Toti L, Viret O (1992) Ecology, metabolite production, and substrate utilization in endophytic fungi. Nat Tox 1:185–196
77. Pujiyanto S, Lestari Y, Suwanto A, Budiarti S, Darusman LK (2012) Alpha-glucosidase inhibitor activity and characterization of endophytic actinomycetes isolated from some Indonesian diabetic medicinal plants. Int J Pharm Pharm Sci 4(1):327–333
78. Pullen C, Schmitz P, Meurer K, Bamberg DD, Lohman S, De Castro Franca S, Groth I, Schlegel B, Mollmann U, Gollmick F, Grafe U, Leistner E (2002) New and bioactive compounds from Streptomyces strains residing in the wood of Celastraceae. Planta 216:162–167
79. Qin S, Li J, Zhao GZ, Chen HH, Xu LH, Li WJ (2008a) Saccharopolyspora endophytica sp. nov. an endophytic actinomycete isolated from the root of Maytenus austroyunnanensis. Syst Appl Microbiol 31:352–357
80. Qin S, Wang HB, Chen HH, Zhang YQ, Jiang CL, Xu LH et al (2008b) Glycomyces endophyticus sp. nov. an endophytic actinomycete isolated from the root of Carex baccans Nees. Int J Syst Evol Microbiol 58:2525–2528
81. Qin S, Jie L, Hua-Hong C, Guo-Zhen Z, Wen-Yong Z, Cheng- Lin J et al (2009) Isolation diversity and antimicrobial activity of rare actinobacteria from medicinal plants of tropical rain forests in Xishuangbanna. China App Environ Microbiol 75:6176–6186
82. Qin S, Xing K, Jiang J, Xu L, Li W (2011) Biodiversity, bioactive natural products and biotechnological potential of plant-associated endophytic actinobacteria. Appl Microbiol Biotechnol 89:457–473
83. Qin S, Yuan B, Zhang YJ, Bian GK, Tamura T, Sun BZ, Li WJ, Jiang JH (2012a) Nocardioides panzhihuaensis sp. nov. a novel endophytic actinomycete isolated from medicinal plant Jatropha curcas L. Ant van Leeuw 102:353–360
84. Qin S, Chen HH, Zhao GZ, Li J, Zhu WY, Xu LH et al (2012b) Abundant and diverse endophytic actinobacteria associated with medicinal plant Maytenus austroyunnanensis in Xishuangbanna tropical rainforest revealed by culture-dependent and culture-independent methods. Environ Microbiol Rep 4(5):522–531
85. Rai M, Agarkar G, Rathod D (2014a) Multiple applications of endophytic Colletotrichum species occurring in medicinal plants, in novel plant bioresources: Applications in food, medicine and cosmetics. In: Gurib-Fakim A (ed) Novel plant bioresources. Wiley, Chichester, pp 227–236
86. Rai M, Rathod D, Agarkar G, Dar M, Brestic M, Marostica Junior MR (2014b) Fungal growth promotor endophytes: a pragmatic approach towards sustainable food and agriculture. Symbiosis 62:63–79
87. Rossellò-Mora R, Amann R (2001) The species concept for prokaryotes. FEMS Microbiol 25:39–67
88. Rungin S, Indanand C, Suttiviriya P, Kruasuwan W, Jaemsaeng R, Thamchaipenet A (2012) Plant growth enhancing effects by a siderophore producing endophytic streptomycete isolated from a Thai jasmine rice plant (Oryza sativa L. cv. KDML105). Ant van Leeuw 102:463–472
89. Rya RPK, Germaine A, Franks DJ, Ryan DN (2007) Bacterial endophytes: recent developments and applications. FEMS Microbiol Lett 278(1):1–9
90. Schulz B, Boyle C (2006) Microbial root endophytes. In: Sieber TN (ed) What are endophytes?, vol 9. Springer, Berlin, pp 1–13
91. Schulz D, Nachtigall J, Riedlinger J, Schneider K, Poralla K, Imhoff JF et al (2009) Piceamycin and its N-acetylcysteine adduct is produced by Streptomyces sp. GB 4-2. J Antibiot 62:513–518
92. Sharma M (2014) Actinomycetes: source, identification, and their applications. Int J Curr Microbiol Appl Sci 3(2):801–832
93. Shenpagam NH, Kanchana D, Sinduja G, Sandhya R (2012) Isolation of endophytic actinomycetes from medicinal plants and its mutational effect in biocontrol activity. Int J Pharm Sci Res 3(11):4338–4344
94. Shimizu M (2011) Endophytic actinomycetes: biocontrol agents and growth promoters. In: Maheshwari DK (ed) Bacteria in agrobiology: plant growth responses. Elsevier Academic Press, San Diego, pp 201–220
95. Shutsrirung A, Chromkaew Y, Pathom-Aree W, Choonluchanon S, Boonkerd N (2014) Diversity of endophytic actinomycetes in mandarin grown in northern Thailand, their phytohormone production potential and plant growth promoting activity. Soil Sci Plant Nutr 59(3):322–330
96. Staniek A, Woerdenbag HJ, Kayser O (2008) Endophytes: exploiting biodiversity for the improvement of natural product-based drug discovery. J Plant Interact 3:75–98
97. Stierle A, Strobel G, Stierle D (1993) Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of pacific yew. Science 260:214–216
98. Strobel G, Daisy B (2003) Bioprospecting for microbial endophytes and their natural products. Microbiol Mol Biol Rev 67:491–502
99. Sunaryanto R, Mahsunah AH (2013) Isolation, purification, and characterization of antimicrobial substances from endophytic actinomycetes. Makara J Sci 17(3):87–92
100. Taechowisan T, Lumyong S (2003) Activity of endophytic actinomycetes from roots of Zingiber officinale and Alpinia galanga against phytopathogenic fungi. Ann Microbiol 53(3):291–298
101. Taechowisan T, Peberdy JF, Lumyong S (2003) Isolation of endophytic actinomycetes from selected plants and their antifungal activity. World J Microbiol Biotechnol 19:381–385
102. Taechowisan T, Lu C, Shen Y, Lumyong S (2005) Secondary metabolites from endophytic Streptomyces aureofaciens CMUAc130 and their antifungal activity. Microbiology 151:1691–1695
103. Taechowisan T, Wanbanjob A, Tuntiwachwuttikul P, Taylor WC (2006) Identification of Streptomyces sp. Tc022, an endophyte in Alpinia galanga, and the isolation of actinomycin D. Ann Microbiol 56:113–117
104. Taechowisan T, Lu C, Shen Y, Lumyong S (2007) Antitumor activity of 4-arylcoumarins from endophytic Streptomyces aureofaciens CMUAc130. J Cancer Res Ther 3(2):86–91
105. Takahashi Y, Omura S (2003) Isolation of new actinomycete strains for the screening of new bioactive compounds. J Gen Appl Microbiol 49:141–154
106. Tan HM, Cao LX, He ZF, Su GJ, Lin B, Zhou SN (2006) Isolation of endophytic actinomycetes from different cultivars of tomato and their activities against Ralstonia solanacearum in vitro. World J Microbiol Biotechnol 22:1275–1280
107. Tanvir R, Sajid I, Hasnain S (2014) Larvicidal potential of Asteraceae family endophytic actinomycetes against Culex quinquefasciatus mosquito larvae. Nat Prod Res 28(22):2048–2052
108. Udwary DW, Ziegler L, Asolbar HN, Singan V, Lapidus A, Fenical W et al (2007) Genome sequencing reveals complete secondary metabolome in the marine actinomycete Salinispora tropica. Proc Natl Acad Sci USA 104:10376–10381
109. Verma VC, Gond SK, Kumar A, Mishra A, Kharwar RN, Gnage A (2009) Endophytic actinomycetes from Azadirachta indica A. Juss.: isolation, diversity, and anti-microbial activity. Microbial Ecol 57:749–756
110. Wang HX, Geng ZL, Zeng Y, Shen YM (2008) Enrichment plant microbiota for a metagenomic libraryconstruction. Environ Microbiol 10:2684–2691
111. Wang P, Kong F, Wei J, Wang Y, Wang W, Hong K et al (2014) Alkaloids from the mangrove-derived actinomycete Jishengella endophytica 161111. Mar Drug 12:477–490
112. Wayne LG, Brenner DJ, Colwell RR, Grimont PAD, Kandler O, Krichevsky ML et al (1987) Report of the ad hoc committee on reconciliation of approaches to bacterial systematics. Int J Syst Bacteriol 37:463–464
113. Williams ST, Davies FL (1965) Use of antibiotics for selective isolation and enumeration of actinomycetes in soil. J Gen Microbiol 38:251–262
114. Zhang X, Ren K, Zhang L (2012) Screening and preliminary identification of medicinal plants endophytic actinomycetes used for inhibiting penicillin-resistant Staphylococcus aureus. Int J Biol 4(2):119–124
115. Zhang YJ, Zhang WD, Qin S, Bian GK, Xing K, Li YF et al (2013) Saccharopolyspora dendranthemae sp. nov. a halotolerant endophytic actinomycete isolated from a coastal salt marsh plant in Jiangsu, China. Ant van Leeuw 103:1369–1376
116. Zhang J, Wang JD, Liu CX, Yuan JH, Wang XJ, Xiang WS (2014) A new prenylated indole derivative from endophytic actinobacteria Streptomyces sp. neau-D50. Nat Prod Res 28(7):431–437
117. Zhao K, Penttinen P, Guan T, Xiao J, Chen Q, Xu J et al (2011) The diversity and anti-microbial activity of endophytic actinomycetes isolated from medicinal plants in Panxi Plateau China. Curr Microbiol 62:182–190
118. Zhou H, Yang Y, Zhang J, Peng T, Zhao L, Xu L et al (2013) Alkaloids from an endophytic Streptomyces sp. YIM66017. Nat Prod Commun 8(10):1393–1396
119. Zhou H, Yang Y, Peng T, Li W, Zhao L, Xu L, Ding Z (2014) Metabolites of Streptomyces sp. an endophytic actinomycete fromAlpinia oxyphylla. Nat Prod Res 28(4):265–267