Brartemicin, an inhibitor of tumor cell invasion from the actinomycete Nonomuraea sp.

Journal of Natural Products

Volumn 72, Issue 5, 2009, Pages 980-982

  Igarashi, Yasuhiro ^a   Mogi, Tsukasa ^a   Yanase, Saeko ^a   Miyanaga, Satoshi ^a   Fujita, Tsuyoshi ^b   Sakurai, Hiroaki ^c   Saiki, Ikuo ^c   Ohsaki, Ayumi ^d  

^a TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^b SUNTORY INSTITUTE FOR BIOORGANIC RESEARCH   (Japan)

^c UNIVERSITY OF TOYAMA   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BRARTEMICIN; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CARBON NUCLEAR MAGNETIC RESONANCE; COLON CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; IC 50; NONHUMAN; NONOMURAEA; NUCLEOTIDE SEQUENCE; PROTON NUCLEAR MAGNETIC RESONANCE;

ACTINOBACTERIA; ANIMALS; ANTINEOPLASTIC AGENTS; ARTEMISIA; COLONIC NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; INHIBITORY CONCENTRATION 50; MICE; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; TREHALOSE;

MURINAE; NONOMURAEA;

EID: 66449092577     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np9000575     Document Type: Article

References (13)

1. Bioactive microbial metabolites. Part 34. Part 33: Azumi, M.; Ogawa, K.; Fujita, T.; Takeshita, M.; Yoshida, R.; Furumai, T.; Igarashi, Y. Tetrahedron 2008, 64, 6420-6425.
2. Kohn, E. C.; Liotta, L. A. Cancer Res. 1995, 51, 1856-1862.
3. Geho, D. H.; Bandle, R. W.; Clair, T.; Liotta, L. A. Physiology 2005, 20, 194-200.
4. (a) Miyanaga, S.; Obata, T.; Onaka, H.; Fujita, T.; Saito, N.; Sakurai, H.; Saiki, I.; Furumai, T.; Igarashi, Y. J. Antibiot. 2006, 59, 698-703.
5. (b) Igarashi, Y.; Trujillo, M. E.; Martinez-Molina, E.; Yanase, S.; Miyanaga, S.; Obata, T.; Sakurai, H.; Saiki, I.; Fujita, T.; Furumai, T. Bioorg. Med. Chem. Lett. 2007, 17, 3702-3705.
6. (c) Miyanaga, S.; Sakurai, H.; Saiki, I.; Onaka, H.; Igarashi, Y. Bioorg. Med. Chem. 2009, in press. DOI: 10.1016/j.bmc.2009.02.040.
7. Igarashi, Y.; Iida, T.; Yoshida, R.; Furumai, T. J. Antibiot. 2002, 55, 764-767.
8. Saito, K. I.; Oku, T.; Ata, N.; Miyashiro, H.; Hattori, M.; Saiki, I. Biol. Pharm. 1997, 20, 345-348.
9. Agatsuma, T.; Takahashi, A.; Kabuto, C.; Nozoe, S. Chem. Pharm. Bull. 1993, 41, 373-375.
10. Birch, G.; Richardson, A. C. Carbohydr. Res. 1968, 8, 411-415.
11. Bottle, S.; Jenkins, D. J. Chem. Soc., Chem. Commun. 1984, 385.
12. Umemura, K.; Matsuyama, H.; Kobayashi, M.; Kamigata, N. Bull. Chem. Soc. Jpn. 1989, 62, 3026-3028.
13. Kanai, F.; Isshiki, K.; Umezawa, Y.; Morishima, H.; Naganawa, H.; Takita, T.; Takeuchi, T.; Umezawa, H. J. Antibiot. 1985, 38, 31-38.