Cinnamic aldehyde suppresses hypoxia-induced angiogenesis via inhibition of hypoxia-inducible factor-1α expression during tumor progression

Biochemical Pharmacology

Volumn 98, Issue 1, 2015, Pages 41-50

  Bae, Woom Yee ^a   Choi, Jae Sun ^a   Kim, Ja Eun ^a   Jeong, Joo Won ^a  

^a Kyung Hee University Hospital   (South Korea)

Author keywords

Angiogenesis; Cinnamic aldehyde; Hypoxia inducible factor 1 ; Tumor

Indexed keywords

CINNAMALDEHYDE; COBALT CHLORIDE; HEMOGLOBIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; VASCULOTROPIN; VON HIPPEL LINDAU PROTEIN; ACROLEIN; ANTINEOPLASTIC AGENT; HIF1A PROTEIN, MOUSE; MTOR PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER INHIBITION; CAPILLARY DENSITY; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; EMBRYO; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; KIDNEY CARCINOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; RENAL CANCER CELL LINE; TUMOR VOLUME; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; ANOXIA; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CELL MOTION; COMPLICATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; VASCULARIZATION;

ACROLEIN; ANIMALS; ANOXIA; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL MOVEMENT; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; MICE; MICE, INBRED BALB C; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOR SERINE-THREONINE KINASES;

EID: 84943449001     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2015.08.095     Document Type: Article

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