Induction of Tumor Cell Death through Targeting Tubulin and Evoking Dysregulation of Cell Cycle Regulatory Proteins by Multifunctional Cinnamaldehydes

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Nagle, Amrita A ^a   Gan, Fei Fei ^a   Jones, Gavin ^b   So, Choon Leng ^a   Wells, Geoffrey ^b   Chew, Eng Hui ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 BENZOYLOXYCINNAMALDEHYDE; 5 FLUORO 2 BENZOYLOXYCINNAMALDEHYDE; 5 FLUORO 2 HYDROXYCINNAMALDEHYDE; BIOTIN; CASPASE 3; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 20; CINNAMALDEHYDE DERIVATIVE; CINNAMIC ACID; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; IODOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN CDC25C; PROTEIN MAD2; PROTEIN TYROSINE PHOSPHATASE; REGULATOR PROTEIN; SURVIVIN; THIOL DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE CHECKPOINT; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE REGULATION; CELL FRACTIONATION; CELL FREE SYSTEM; CELL LYSATE; CELL STRAIN HCT116; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG POTENCY; DRUG POTENTIATION; DRUG STRUCTURE; DRUG TARGETING; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; PROTEIN AGGREGATION; PROTEIN SYNTHESIS INHIBITION; STRUCTURE ANALYSIS;

ACROLEIN; ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZOATES; CASPASE 3; CELL CYCLE PROTEINS; CELL LINE, TUMOR; FUNGAL PROTEINS; G2 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION; HISTONES; HUMANS; POLY(ADP-RIBOSE) POLYMERASES; TUBULIN; VIRULENCE FACTORS;

EID: 84869792697     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050125     Document Type: Article

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