Adaptive landscapes of resistance genes change as antibiotic concentrations change

Molecular Biology and Evolution

Volumn 32, Issue 10, 2015, Pages 2707-2715

  Mira, Portia M ^a   Meza, Juan C ^a   Nandipati, Anna ^a   Barlow, Miriam ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

adaptive landscapes; antibiotic concentrations; antibiotic resistance; epistasis; genotype by environment interactions; inhibitor resistant; lactam

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; ANTIBIOTIC AGENT; BETA LACTAM; BETA LACTAMASE; CEFEPIME; CEFOTAXIME; CEFOTETAN; CEFPROZIL; CEFTAZIDIME; PENICILLIN DERIVATIVE; PIPERACILLIN PLUS TAZOBACTAM; SULTAMICILLIN; ANTIINFECTIVE AGENT; CEPHALOSPORIN DERIVATIVE;

ADAPTIVE BEHAVIOR; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; EVOLUTION; FITNESS; GENOTYPE; SPONTANEOUS MUTATION; TRANSMISSION ELECTRON MICROSCOPY; ADAPTATION; ALLELE; BACTERIAL GENE; DRUG EFFECTS; GENETICS;

ADAPTATION, PHYSIOLOGICAL; ALLELES; ANTI-BACTERIAL AGENTS; BETA-LACTAMS; CEPHALOSPORINS; DRUG RESISTANCE, MICROBIAL; GENES, BACTERIAL;

EID: 84943420691     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msv146     Document Type: Article

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