Hypertonic saline for the management of raised intracranial pressure after severe traumatic brain injury

Annals of the New York Academy of Sciences

Volumn 1345, Issue 1, 2015, Pages 83-88

  Mangat, Halinder S ^a   Härtl, Roger ^a  

^a NEW YORK PRESBYTERIAN HOSPITAL   (United States)

Author keywords

Hyperosmotics; Hypertonic saline; Intracranial hypertension; Intracranial pressure; Mannitol; Traumatic brain injury

Indexed keywords

BARBITURIC ACID DERIVATIVE; MANNITOL; SODIUM CHLORIDE;

ARTICLE; BLOOD VOLUME; BRAIN BLOOD FLOW; BRAIN PERFUSION; DRUG USE; HUMAN; INJURY SEVERITY; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; META ANALYSIS; MORTALITY; OUTCOME ASSESSMENT; PILOT STUDY; TRAUMATIC BRAIN INJURY; BRAIN INJURIES; COMPLICATION; DRUG EFFECTS; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

BRAIN INJURIES; HUMANS; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; MANNITOL; PILOT PROJECTS; SALINE SOLUTION, HYPERTONIC; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 84943404527     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/nyas.12704     Document Type: Article

References (64)

1. Mokri, B. 2001. The Monro-Kellie hypothesis: applications in CSF volume depletion. Neurology 56: 1746-1748.
2. Badri, S. et al. 2012. Mortality and long-term functional outcome associated with intracranial pressure after traumatic brain injury. Intensive Care Med. 38: 1800-1809.
3. Stein, D.M. et al. 2011. Brief episodes of intracranial hypertension and cerebral hypoperfusion are associated with poor functional outcome after severe traumatic brain injury. J. Trauma 71: 364-373; discussion 373-364.
4. Chesnut, R.M. et al. 2012. A trial of intracranial-pressure monitoring in traumatic brain injury. N. Engl. J. Med. 367: 2471-2481.
5. Brain Trauma Foundation et al. 2007. Guidelines for the management of severe traumatic brain injury. VIII. Intracranial pressure thresholds. J. Neurotrauma 24(Suppl. 1): S55-S58.
6. Brain Trauma Foundation et al. 2007. Guidelines for the management of severe traumatic brain injury. VI. Indications for intracranial pressure monitoring. J. Neurotrauma 24(Suppl. 1): S37-S44.
7. Gerber, L.M. et al. 2013. Marked reduction in mortality in patients with severe traumatic brain injury. J. Neurosurg 119: 1583-1590.
8. Farahvar, A. et al. 2012. Increased mortality in patients with severe traumatic brain injury treated without intracranial pressure monitoring. J. Neurosurg. 117: 729-734.
9. Farahvar, A. et al. 2011. Response to intracranial hypertension treatment as a predictor of death in patients with severe traumatic brain injury. J. Neurosurg. 114: 1471-1478.
10. Brain Trauma Foundation, American Association of Neurological Surgeons & Congress of Neurological Surgeons. 2007. Guidelines for the management of severe traumatic brain injury. J. Neurotrauma 24(Suppl. 1): S1-S106.
11. Jeevaratnam, D.R. & D.K. Menon . 1996. Survey of intensive care of severely head injured patients in the United Kingdom. BMJ. 312: 944-947.
12. Brain Trauma Foundation et al. 2007. Guidelines for the management of severe traumatic brain injury. II. Hyperosmolar therapy. J. Neurotrauma 24(Suppl. 1): S14-S20.
13. Muizelaar, J.P. et al. 1983. Mannitol causes compensatory cerebral vasoconstriction and vasodilation in response to blood viscosity changes. J. Neurosurg. 59: 822-828.
14. Mendelow, A.D. et al. 1985. Effect of mannitol on cerebral blood flow and cerebral perfusion pressure in human head injury. J. Neurosurg. 63: 43-48.
15. Nath, F. & S. Galbraith . 1986. The effect of mannitol on cerebral white matter water content. J. Neurosurg. 65: 41-43.
16. Muizelaar, J.P., H.A. Lutz 3rd & D.P. Becker . 1984. Effect of mannitol on ICP and CBF and correlation with pressure autoregulation in severely head-injured patients. J. Neurosurg. 61: 700-706.
17. Burke, A.M. et al. 1981. The effects of mannitol on blood viscosity. J. Neurosurg. 55: 550-553.
18. Berger, S. et al. 1995. Reduction of post-traumatic intracranial hypertension by hypertonic/hyperoncotic saline/dextran and hypertonic mannitol. Neurosurgery 37: 98-107; discussion 107-108.
19. Willerson, J.T. et al. 1975. Influence of hypertonic mannitol on ventricular performance and coronary blood flow in patients. Circulation 51: 1095-1100.
20. Marks, J.A. et al. 2012. Similar effects of hypertonic saline and mannitol on the inflammation of the blood-brain barrier microcirculation after brain injury in a mouse model. J. Trauma Acute Care Surg. 73: 351-357; discussion 357.
21. Marshall, L.F. et al. 1978. Mannitol dose requirements in brain-injured patients. J. Neurosurg. 48: 169-172.
22. Schwartz, M.L. et al. 1984. The University of Toronto head injury treatment study: a prospective, randomized comparison of pentobarbital and mannitol. Can. J. Neurol. Sci. 11: 434-440.
23. Smith, H.P. et al. 1986. Comparison of mannitol regimens in patients with severe head injury undergoing intracranial monitoring. J. Neurosurg. 65: 820-824.
24. Sakowitz, O.W. et al. 2007. Effects of mannitol bolus administration on intracranial pressure, cerebral extracellular metabolites, and tissue oxygenation in severely head-injured patients. J. Trauma 62: 292-298.
25. Colton, K. et al. 2014. Intracranial pressure response after pharmacologic treatment of intracranial hypertension. J. Trauma Acute Care Surg. 77: 47-53; discussion 53.
26. Sorani, M.D. et al. 2008. Characterizing the dose-response relationship between mannitol and intracranial pressure in traumatic brain injury patients using a high-frequency physiological data collection system. J. Neurotrauma. 25: 291-298.
27. Battison, C. et al. 2005. Randomized, controlled trial on the effect of a 20% mannitol solution and a 7.5% saline/6% dextran solution on increased intracranial pressure after brain injury. Crit. Care Med. 33: 196-202; discussion 257-198.
28. Francony, G. et al. 2008. Equimolar doses of mannitol and hypertonic saline in the treatment of increased intracranial pressure. Crit. Care Med. 36: 795-800.
29. Kaufmann, A.M. & E.R. Cardoso . 1992. Aggravation of vasogenic cerebral edema by multiple-dose mannitol. J. Neurosurg. 77: 584-589.
30. Horn, P. et al. 1999. Hypertonic saline solution for control of elevated intracranial pressure in patients with exhausted response to mannitol and barbiturates. Neurol. Res. 21: 758-764.
31. Oddo, M. et al. 2009. Effect of mannitol and hypertonic saline on cerebral oxygenation in patients with severe traumatic brain injury and refractory intracranial hypertension. J. Neurol. Neurosurg. Psychiatry 80: 916-920.
32. Battistella, F.D. & D.H. Wisner . 1991. Combined hemorrhagic shock and head injury: effects of hypertonic saline (7.5%) resuscitation. J. Trauma 31: 182-188.
33. Toung, T.J. et al. 2007. Osmotherapy with hypertonic saline attenuates water content in brain and extracerebral organs. Crit. Care Med. 35: 526-531.
34. Wisner, D.H., L. Schuster & C. Quinn . 1990. Hypertonic saline resuscitation of head injury: effects on cerebral water content. J. Trauma 30: 75-78.
35. Kramer, G.C. 2003. Hypertonic resuscitation: physiologic mechanisms and recommendations for trauma care. J. Trauma 54: S89-S99.
36. Frithiof, R. et al. 2007. Intravenous hypertonic NaCl acts via cerebral sodium-sensitive and angiotensinergic mechanisms to improve cardiac function in haemorrhaged conscious sheep. J. Physiol. 583: 1129-1143.
37. Frithiof, R. et al. 2011. Hypertonic sodium resuscitation after hemorrhage improves hemodynamic function by stimulating cardiac, but not renal, sympathetic nerve activity. Am. J. Physiol. Heart Circ. Physiol. 300: H685-H692.
38. Hartl, R. et al. 1997. Hypertonic/hyperoncotic saline attenuates microcirculatory disturbances after traumatic brain injury. J. Trauma 42: S41-S47.
39. Soustiel, J.F., E. Vlodavsky & M. Zaaroor . 2006. Relative effects of mannitol and hypertonic saline on calpain activity, apoptosis and polymorphonuclear infiltration in traumatic focal brain injury. Brain Res. 1101: 136-144.
40. Schatzmann, C. et al. 1998. Treatment of elevated intracranial pressure by infusions of 10% saline in severely head injured patients. Acta Neurochir. Suppl. 71: 31-33.
41. Hartl, R. et al. 1997. Hypertonic/hyperoncotic saline reliably reduces ICP in severely head-injured patients with intracranial hypertension. Acta Neurochir. Suppl. 70: 126-129.
42. Koenig, M.A. et al. 2008. Reversal of transtentorial herniation with hypertonic saline. Neurology 70: 1023-1029.
43. Roquilly, A. et al. 2011. Continuous controlled-infusion of hypertonic saline solution in traumatic brain-injured patients: a 9-year retrospective study. Crit. Care 15: R260.
44. Eskandari, R. et al. 2013. Effective treatment of refractory intracranial hypertension after traumatic brain injury with repeated boluses of 14.6% hypertonic saline. J. Neurosurg. 119: 338-346.
45. Hartl, R. et al. 1997. Treatment of refractory intracranial hypertension in severe traumatic brain injury with repetitive hypertonic/hyperoncotic infusions. Zentralblatt fur Chirurgie. 122: 181-185.
46. Rockswold, G.L. et al. 2009. Hypertonic saline and its effect on intracranial pressure, cerebral perfusion pressure, and brain tissue oxygen. Neurosurgery 65: 1035-1041; discussion 1041-1032.
47. Dias, C. et al. 2014. Post-traumatic multimodal brain monitoring: response to hypertonic saline. J. Neurotrauma 31: 1872-1880.
48. Kerwin, A.J. et al. 2009. The use of 23.4% hypertonic saline for the management of elevated intracranial pressure in patients with severe traumatic brain injury: a pilot study. J. Trauma 67: 277-282.
49. Cottenceau, V. et al. 2011. Comparison of effects of equiosmolar doses of mannitol and hypertonic saline on cerebral blood flow and metabolism in traumatic brain injury. J. Neurotrauma 28: 2003-2012.
50. Froelich, M. et al. 2009. Continuous hypertonic saline therapy and the occurrence of complications in neurocritically ill patients. Crit. Care Med. 37: 1433-1441.
51. Khanna, S. et al. 2000. Use of hypertonic saline in the treatment of severe refractory posttraumatic intracranial hypertension in pediatric traumatic brain injury. Crit. Care Med. 28: 1144-1151.
52. Peterson, B. et al. 2000. Prolonged hypernatremia controls elevated intracranial pressure in head-injured pediatric patients. Crit. Care Med. 28: 1136-1143.
53. Gonda, D.D. et al. 2013. Complications associated with prolonged hypertonic saline therapy in children with elevated intracranial pressure. Pediatr. Crit. Care Med. 14: 610-620.
54. Lin, K.C. et al. 2008. The early response of mannitol infusion in traumatic brain injury. Acta neurologica Taiwanica. 17: 26-32.
55. Ichai, C. et al. 2009. Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients. Intensive Care Med. 35: 471-479.
56. Vialet, R. et al. 2003. Isovolume hypertonic solutes (sodium chloride or mannitol) in the treatment of refractory posttraumatic intracranial hypertension: 2 mL/kg 7.5% saline is more effective than 2 mL/kg 20% mannitol. Crit. Care Med. 31: 1683-1687.
57. Ware, M.L. et al. 2005. Effects of 23.4% sodium chloride solution in reducing intracranial pressure in patients with traumatic brain injury: a preliminary study. Neurosurgery 57: 727-736; discussion 727-736.
58. Lewandowski-Belfer, J.J. et al. 2014. Safety and efficacy of repeated doses of 14.6 or 23.4% hypertonic saline for refractory intracranial hypertension. Neurocrit. Care 20: 436-442.
59. Manqat, H.S., Y.L . Chiu, L.M. Gerber, et al. 2015. Hypertonic saline reduces cumulative and daily ICP burden after severe traumatic brain injury. J. Neurosurg. 122: 202-210.
60. Hartl, R. et al. 1997. Mannitol decreases ICP but does not improve brain-tissue pO2 in severely head-injured patients with intracranial hypertension. Acta Neurochir. Suppl. 70: 40-42.
61. Unterberg, A.W. et al. 1997. Multimodal monitoring in patients with head injury: evaluation of the effects of treatment on cerebral oxygenation. J. Trauma 42: S32-S37.
62. Sayre, M.R. et al. 1996. Out-of-hospital administration of mannitol to head-injured patients does not change systolic blood pressure. Acad. Emerg. Med. 3: 840-848.
63. Kamel, H. et al. 2011. Hypertonic saline versus mannitol for the treatment of elevated intracranial pressure: a meta-analysis of randomized clinical trials. Crit. Care Med. 39: 554-559.
64. Wakai, A. et al. 2013. Mannitol for acute traumatic brain injury. Cochrane Database Syst. Rev. 8: CD001049.