Safety and efficacy of repeated doses of 14.6 or 23.4 % hypertonic saline for refractory intracranial hypertension

Neurocritical Care

Volumn 20, Issue 3, 2014, Pages 436-442

  Lewandowski Belfer, Julie J ^a,b   Patel, Alden V ^b   Darracott, Robert M ^b   Jackson, Daniel A ^b   Nordeen, Jerah D ^b   Freeman, W David ^b  

^a Department of Pharmacy Spectrum Health Butterworth ^*  (United States)

^b MAYO CLINIC   (United States)

Author keywords

Hyperosmolar agents; Hypertonic saline; Intracranial hypertension; Intracranial pressure; Osmotherapy; Serum sodium

Indexed keywords

SODIUM; SODIUM CHLORIDE;

ABNORMAL LABORATORY RESULT; ADULT; AGED; CENTRAL PONTINE MYELINOLYSIS; COHORT ANALYSIS; DEATH; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; ELECTROLYTE BLOOD LEVEL; FEMALE; FLUID THERAPY; HUMAN; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; MAJOR CLINICAL STUDY; MALE; PATIENT MONITORING; PRIORITY JOURNAL; REFRACTORY INTRACRANIAL HYPERTENSION; REPEATED DRUG DOSE; RETROSPECTIVE STUDY; REVIEW; SERUM OSMOLALITY; SINGLE DRUG DOSE; SODIUM BLOOD LEVEL; BRAIN INJURIES; CRITICAL ILLNESS; DRUG EFFECTS; MIDDLE AGED; MORTALITY; OSMOLARITY; TREATMENT OUTCOME; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; BRAIN INJURIES; CRITICAL ILLNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; MALE; MIDDLE AGED; OSMOLAR CONCENTRATION; RETROSPECTIVE STUDIES; SALINE SOLUTION, HYPERTONIC; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84902369800     PISSN: 15416933     EISSN: 15560961     Source Type: Journal    
DOI: 10.1007/s12028-013-9907-1     Document Type: Review

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