Intravenous hypertonic NaCl acts via cerebral sodium-sensitive and angiotensinergic mechanisms to improve cardiac function in haemorrhaged conscious sheep

Journal of Physiology

Volumn 583, Issue 3, 2007, Pages 1129-1143

  Frithiof, Robert ^a   Eriksson, Stefan ^a   Bayard, Frida ^a   Svensson, Tor ^a   Rundgren, Mats ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; LOSARTAN; MANNITOL; SODIUM CHLORIDE; SODIUM ION; HYPERTONIC SOLUTION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; BLEEDING DISORDER; BLOOD OSMOLARITY; CARDIOVASCULAR RESPONSE; CEREBROSPINAL FLUID; CONSCIOUSNESS; CONTROLLED STUDY; DRUG MECHANISM; FLUID RESUSCITATION; HEART INDEX; HEMODYNAMICS; HYPOVOLEMIA; MESENTERY BLOOD FLOW; NONHUMAN; OUTCOME ASSESSMENT; PLASMA VOLUME; PRIORITY JOURNAL; ARTIFICIAL CEREBROSPINAL FLUID; BRAIN LEVEL; FEMALE; HEART FUNCTION; HEMORRHAGIC HYPOTENSION; MEAN ARTERIAL PRESSURE; OSMOLALITY; SHEEP;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; CONSCIOUSNESS; DIURETICS, OSMOTIC; FEMALE; HEMORRHAGE; HYPOVOLEMIA; INFUSIONS, INTRAVENOUS; INJECTIONS, INTRAVENTRICULAR; LOSARTAN; MANNITOL; OSMOLAR CONCENTRATION; RECEPTOR, ANGIOTENSIN, TYPE 1; RESUSCITATION; SALINE SOLUTION, HYPERTONIC; SHEEP; SODIUM; VASCULAR RESISTANCE; VASOPRESSINS;

EID: 34548748162     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.139592     Document Type: Article

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