-
1
-
-
81555200043
-
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
-
Zlokovic B.V. Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. Nat. Rev. Neurosci. 2011, 12:723-738. 10.1038/nrn3114.
-
(2011)
Nat. Rev. Neurosci.
, vol.12
, pp. 723-738
-
-
Zlokovic, B.V.1
-
2
-
-
84888019151
-
The pathobiology of vascular dementia
-
Iadecola C. The pathobiology of vascular dementia. Neuron 2013, 80:844-866. 10.1016/j.neuron.2013.10.008.
-
(2013)
Neuron
, vol.80
, pp. 844-866
-
-
Iadecola, C.1
-
3
-
-
84928213789
-
The molecular, cellular, and morphological components of blood-brain barrier development during embryogenesis
-
Hagan N., Ben-Zvi A. The molecular, cellular, and morphological components of blood-brain barrier development during embryogenesis. Semin. Cell Dev. Biol. 2015, 38:7-15. 10.1016/j.semcdb.2014.12.006.
-
(2015)
Semin. Cell Dev. Biol.
, vol.38
, pp. 7-15
-
-
Hagan, N.1
Ben-Zvi, A.2
-
4
-
-
78649487239
-
Pericytes are required for blood-brain barrier integrity during embryogenesis
-
Daneman R., Zhou L., Kebede A.A., Barres B.A. Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature 2010, 468:562-566. 10.1038/nature09513.
-
(2010)
Nature
, vol.468
, pp. 562-566
-
-
Daneman, R.1
Zhou, L.2
Kebede, A.A.3
Barres, B.A.4
-
5
-
-
78649467527
-
Pericytes regulate the blood-brain barrier
-
Armulik A., Genové G., Mäe M., Nisancioglu M.H., Wallgard E., Niaudet C., et al. Pericytes regulate the blood-brain barrier. Nature 2010, 468:557-561. 10.1038/nature09522.
-
(2010)
Nature
, vol.468
, pp. 557-561
-
-
Armulik, A.1
Genové, G.2
Mäe, M.3
Nisancioglu, M.H.4
Wallgard, E.5
Niaudet, C.6
-
6
-
-
78049279739
-
Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging
-
Bell R.D., Winkler E.A., Sagare A.P., Singh I., LaRue B., Deane R., et al. Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging. Neuron 2010, 68:409-427. 10.1016/j.neuron.2010.09.043.
-
(2010)
Neuron
, vol.68
, pp. 409-427
-
-
Bell, R.D.1
Winkler, E.A.2
Sagare, A.P.3
Singh, I.4
LaRue, B.5
Deane, R.6
-
7
-
-
0035047718
-
Cerebral microvascular pathology in aging and Alzheimer's disease
-
Farkas E., Luiten P.G. Cerebral microvascular pathology in aging and Alzheimer's disease. Prog. Neurobiol. 2001, 64:575-611.
-
(2001)
Prog. Neurobiol.
, vol.64
, pp. 575-611
-
-
Farkas, E.1
Luiten, P.G.2
-
8
-
-
84951568640
-
Accelerated pericyte degeneration and blood-brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer's disease
-
Halliday M.R., Rege S.V., Ma Q., Zhao Z., Miller C.A., Winkler E.A., et al. Accelerated pericyte degeneration and blood-brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer's disease. J. Cereb. Blood Flow Metab. Off. J. Int. Soc. Cereb. Blood Flow Metab. 2015, 10.1038/jcbfm.2015.44.
-
(2015)
J. Cereb. Blood Flow Metab. Off. J. Int. Soc. Cereb. Blood Flow Metab.
-
-
Halliday, M.R.1
Rege, S.V.2
Ma, Q.3
Zhao, Z.4
Miller, C.A.5
Winkler, E.A.6
-
9
-
-
84921326695
-
Blood-brain barrier breakdown in the aging human hippocampus
-
Montagne A., Barnes S.R., Sweeney M.D., Halliday M.R., Sagare A.P., Zhao Z., et al. Blood-brain barrier breakdown in the aging human hippocampus. Neuron 2015, 85:296-302. 10.1016/j.neuron.2014.12.032.
-
(2015)
Neuron
, vol.85
, pp. 296-302
-
-
Montagne, A.1
Barnes, S.R.2
Sweeney, M.D.3
Halliday, M.R.4
Sagare, A.P.5
Zhao, Z.6
-
10
-
-
84876288324
-
Deficiency in mural vascular cells coincides with blood-brain barrier disruption in Alzheimer's disease
-
Sengillo J.D., Winkler E.A., Walker C.T., Sullivan J.S., Johnson M., Zlokovic B.V. Deficiency in mural vascular cells coincides with blood-brain barrier disruption in Alzheimer's disease. Brain Pathol. Zurich Switz. 2013, 23:303-310. 10.1111/bpa.12004.
-
(2013)
Brain Pathol. Zurich Switz.
, vol.23
, pp. 303-310
-
-
Sengillo, J.D.1
Winkler, E.A.2
Walker, C.T.3
Sullivan, J.S.4
Johnson, M.5
Zlokovic, B.V.6
-
11
-
-
33847344251
-
Review of the pericyte during angiogenesis and its role in cancer and diabetic retinopathy
-
Hall A.P. Review of the pericyte during angiogenesis and its role in cancer and diabetic retinopathy. Toxicol. Pathol. 2006, 34:763-775. 10.1080/01926230600936290.
-
(2006)
Toxicol. Pathol.
, vol.34
, pp. 763-775
-
-
Hall, A.P.1
-
12
-
-
70449108112
-
Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy
-
Geraldes P., Hiraoka-Yamamoto J., Matsumoto M., Clermont A., Leitges M., Marette A., et al. Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy. Nat. Med. 2009, 15:1298-1306. 10.1038/nm.2052.
-
(2009)
Nat. Med.
, vol.15
, pp. 1298-1306
-
-
Geraldes, P.1
Hiraoka-Yamamoto, J.2
Matsumoto, M.3
Clermont, A.4
Leitges, M.5
Marette, A.6
-
13
-
-
84867083056
-
Blood-spinal cord barrier pericyte reductions contribute to increased capillary permeability
-
Winkler E.A., Sengillo J.D., Bell R.D., Wang J., Zlokovic B.V. Blood-spinal cord barrier pericyte reductions contribute to increased capillary permeability. J. Cereb. Blood Flow Metab. Off. J. Int. Soc. Cereb. Blood Flow Metab. 2012, 32:1841-1852. 10.1038/jcbfm.2012.113.
-
(2012)
J. Cereb. Blood Flow Metab. Off. J. Int. Soc. Cereb. Blood Flow Metab.
, vol.32
, pp. 1841-1852
-
-
Winkler, E.A.1
Sengillo, J.D.2
Bell, R.D.3
Wang, J.4
Zlokovic, B.V.5
-
14
-
-
84872363503
-
Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
-
Winkler E.A., Sengillo J.D., Sullivan J.S., Henkel J.S., Appel S.H., Zlokovic B.V. Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis. Acta Neuropathol. (Berl.) 2013, 125:111-120. 10.1007/s00401-012-1039-8.
-
(2013)
Acta Neuropathol. (Berl.)
, vol.125
, pp. 111-120
-
-
Winkler, E.A.1
Sengillo, J.D.2
Sullivan, J.S.3
Henkel, J.S.4
Appel, S.H.5
Zlokovic, B.V.6
-
15
-
-
84955186682
-
Pericytes are involved in the pathogenesis of CADASIL
-
Ghosh M., Balbi M., Hellal F., Dichgans M., Lindauer U., Plesnila N. Pericytes are involved in the pathogenesis of CADASIL. Ann. Neurol. 2015, 10.1002/ana.24512.
-
(2015)
Ann. Neurol.
-
-
Ghosh, M.1
Balbi, M.2
Hellal, F.3
Dichgans, M.4
Lindauer, U.5
Plesnila, N.6
-
16
-
-
84941268763
-
PDGFRβ (+) cells in human and experimental neuro-vascular dysplasia and seizures
-
Garbelli R., de Bock F., Medici V., Rousset M.C., Villani F., Boussadia B., et al. PDGFRβ (+) cells in human and experimental neuro-vascular dysplasia and seizures. Neuroscience 2015, 306:18-27. 10.1016/j.neuroscience.2015.07.090.
-
(2015)
Neuroscience
, vol.306
, pp. 18-27
-
-
Garbelli, R.1
de Bock, F.2
Medici, V.3
Rousset, M.C.4
Villani, F.5
Boussadia, B.6
-
17
-
-
80055014830
-
Central nervous system pericytes in health and disease
-
Winkler E.A., Bell R.D., Zlokovic B.V. Central nervous system pericytes in health and disease. Nat. Neurosci. 2011, 14:1398-1405. 10.1038/nn.2946.
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1398-1405
-
-
Winkler, E.A.1
Bell, R.D.2
Zlokovic, B.V.3
-
18
-
-
79961230399
-
Pericytes: developmental, physiological, and pathological perspectives, problems, and promises
-
Armulik A., Genové G., Betsholtz C. Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Dev. Cell 2011, 21:193-215. 10.1016/j.devcel.2011.07.001.
-
(2011)
Dev. Cell
, vol.21
, pp. 193-215
-
-
Armulik, A.1
Genové, G.2
Betsholtz, C.3
-
19
-
-
0032768156
-
Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
-
Hellström M., Kalén M., Lindahl P., Abramsson A., Betsholtz C. Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Dev. Camb. Engl. 1999, 126:3047-3055.
-
(1999)
Dev. Camb. Engl.
, vol.126
, pp. 3047-3055
-
-
Hellström, M.1
Kalén, M.2
Lindahl, P.3
Abramsson, A.4
Betsholtz, C.5
-
20
-
-
77955780543
-
Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling
-
Winkler E.A., Bell R.D., Zlokovic B.V. Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling. Mol. Neurodegener. 2010, 5:32. 10.1186/1750-1326-5-32.
-
(2010)
Mol. Neurodegener.
, vol.5
, pp. 32
-
-
Winkler, E.A.1
Bell, R.D.2
Zlokovic, B.V.3
-
21
-
-
84929176515
-
The complex mural cell: pericyte function in health and disease
-
van Dijk C.G.M., Nieuweboer F.E., Pei J.Y., Xu Y.J., Burgisser P., van Mulligen E., et al. The complex mural cell: pericyte function in health and disease. Int. J. Cardiol. 2015, 190:75-89. 10.1016/j.ijcard.2015.03.258.
-
(2015)
Int. J. Cardiol.
, vol.190
, pp. 75-89
-
-
van Dijk, C.G.M.1
Nieuweboer, F.E.2
Pei, J.Y.3
Xu, Y.J.4
Burgisser, P.5
van Mulligen, E.6
-
22
-
-
33846471269
-
Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype
-
Chow N., Bell R.D., Deane R., Streb J.W., Chen J., Brooks A., et al. Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:823-828. 10.1073/pnas.0608251104.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 823-828
-
-
Chow, N.1
Bell, R.D.2
Deane, R.3
Streb, J.W.4
Chen, J.5
Brooks, A.6
-
23
-
-
59649110562
-
SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells
-
Bell R.D., Deane R., Chow N., Long X., Sagare A., Singh I., et al. SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells. Nat. Cell Biol. 2009, 11:143-153. 10.1038/ncb1819.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 143-153
-
-
Bell, R.D.1
Deane, R.2
Chow, N.3
Long, X.4
Sagare, A.5
Singh, I.6
-
24
-
-
0032529151
-
Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1-40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer
-
Mackic J.B., Stins M., McComb J.G., Calero M., Ghiso J., Kim K.S., et al. Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1-40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer. J. Clin. Invest. 1998, 102:734-743. 10.1172/jci2029.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 734-743
-
-
Mackic, J.B.1
Stins, M.2
McComb, J.G.3
Calero, M.4
Ghiso, J.5
Kim, K.S.6
-
25
-
-
24744457932
-
Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease
-
Wu Z., Guo H., Chow N., Sallstrom J., Bell R.D., Deane R., et al. Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease. Nat. Med. 2005, 11:959-965. 10.1038/nm1287.
-
(2005)
Nat. Med.
, vol.11
, pp. 959-965
-
-
Wu, Z.1
Guo, H.2
Chow, N.3
Sallstrom, J.4
Bell, R.D.5
Deane, R.6
-
26
-
-
0001960660
-
Amyloid β-protein precursor in cultured leptomeningeal smooth muscle cells
-
Van Nostrand W., Rozemuller A., Chung R., Cotman C., Saporito-irwin S. Amyloid β-protein precursor in cultured leptomeningeal smooth muscle cells. Amyloid 1994, 1:1-7.
-
(1994)
Amyloid
, vol.1
, pp. 1-7
-
-
Van Nostrand, W.1
Rozemuller, A.2
Chung, R.3
Cotman, C.4
Saporito-irwin, S.5
-
27
-
-
0037928427
-
Amyloid beta-protein stimulates the expression of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) in human cerebrovascular smooth muscle cells
-
Davis J., Wagner M.R., Zhang W., Xu F., Van Nostrand W.E. Amyloid beta-protein stimulates the expression of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) in human cerebrovascular smooth muscle cells. J. Biol. Chem. 2003, 278:19054-19061. 10.1074/jbc.M301398200.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 19054-19061
-
-
Davis, J.1
Wagner, M.R.2
Zhang, W.3
Xu, F.4
Van Nostrand, W.E.5
-
28
-
-
0028179175
-
Induction of alpha-smooth muscle actin expression in cultured human brain pericytes by transforming growth factor-beta 1
-
Verbeek M.M., Otte-Höller I., Wesseling P., Ruiter D.J., de Waal R.M. Induction of alpha-smooth muscle actin expression in cultured human brain pericytes by transforming growth factor-beta 1. Am. J. Pathol. 1994, 144:372-382.
-
(1994)
Am. J. Pathol.
, vol.144
, pp. 372-382
-
-
Verbeek, M.M.1
Otte-Höller, I.2
Wesseling, P.3
Ruiter, D.J.4
de Waal, R.M.5
-
29
-
-
84890576583
-
Pericyte loss influences Alzheimer-like neurodegeneration in mice
-
Sagare A.P., Bell R.D., Zhao Z., Ma Q., Winkler E.A., Ramanathan A., et al. Pericyte loss influences Alzheimer-like neurodegeneration in mice. Nat. Commun. 2013, 4:2932. 10.1038/ncomms3932.
-
(2013)
Nat. Commun.
, vol.4
, pp. 2932
-
-
Sagare, A.P.1
Bell, R.D.2
Zhao, Z.3
Ma, Q.4
Winkler, E.A.5
Ramanathan, A.6
-
30
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R., Head E., Thompson J.L., McIntire T.M., Milton S.C., Cotman C.W., Glabe C.G. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 2003, 300:486-489. 10.1126/science.1079469.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
31
-
-
57449084208
-
ApoE isoform-specific disruption of amyloid β peptide clearance from mouse brain
-
Deane R., Sagare A., Hamm K., Parisi M., Lane S., Finn M.B., et al. apoE isoform-specific disruption of amyloid β peptide clearance from mouse brain. J. Clin. Invest. 2008, 118:4002. 10.1172/JCI36663.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 4002
-
-
Deane, R.1
Sagare, A.2
Hamm, K.3
Parisi, M.4
Lane, S.5
Finn, M.B.6
-
32
-
-
0030756325
-
Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
-
Lindahl P., Johansson B.R., Levéen P., Betsholtz C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science 1997, 277:242-245.
-
(1997)
Science
, vol.277
, pp. 242-245
-
-
Lindahl, P.1
Johansson, B.R.2
Levéen, P.3
Betsholtz, C.4
-
33
-
-
2342419356
-
Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development
-
Tallquist M.D., French W.J., Soriano P. Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. PLoS Biol. 2003, 1:E52. 10.1371/journal.pbio.0000052.
-
(2003)
PLoS Biol.
, vol.1
, pp. E52
-
-
Tallquist, M.D.1
French, W.J.2
Soriano, P.3
-
34
-
-
77955293472
-
Stimulation of platelet-derived growth factor receptor beta (PDGFRbeta) activates ADAM17 and promotes metalloproteinase-dependent cross-talk between the PDGFRbeta and epidermal growth factor receptor (EGFR) signaling pathways
-
Mendelson K., Swendeman S., Saftig P., Blobel C.P. Stimulation of platelet-derived growth factor receptor beta (PDGFRbeta) activates ADAM17 and promotes metalloproteinase-dependent cross-talk between the PDGFRbeta and epidermal growth factor receptor (EGFR) signaling pathways. J. Biol. Chem. 2010, 285:25024-25032. 10.1074/jbc.M110.102566.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 25024-25032
-
-
Mendelson, K.1
Swendeman, S.2
Saftig, P.3
Blobel, C.P.4
-
35
-
-
80053484102
-
Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease
-
Jiang H., Hampel H., Prvulovic D., Wallin A., Blennow K., Li R., et al. Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease. Mol. Neurodegener. 2011, 6:69. 10.1186/1750-1326-6-69.
-
(2011)
Mol. Neurodegener.
, vol.6
, pp. 69
-
-
Jiang, H.1
Hampel, H.2
Prvulovic, D.3
Wallin, A.4
Blennow, K.5
Li, R.6
|