Pancreatic islet-like three-dimensional aggregates derived from human embryonic stem cells ameliorate hyperglycemia in streptozotocin-induced diabetic mice

Cell Transplantation

Volumn 24, Issue 10, 2015, Pages 2155-2168

  Shim, Joong Hyun ^a,b   Kim, Jong Hyun ^a   Han, Jiyou ^a   An, Su Yeon ^a   Jang, Yu Jin ^a   Son, Jeongsang ^a   Woo, Dong Hun ^a   Kim, Suel Kee ^a   Kim, Jong Hoon ^a  

^a Korea University   (South Korea)

^b Semyung University   (South Korea)

Author keywords

B Cells; Diabetes mellitus; Human embryonic stem cells (hESCs); Pancreatic islet; Sodium chlorate

Indexed keywords

ACTIVIN A; ACTIVIN BETA B; BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; CHEMOKINE RECEPTOR CXCR4; CHLORATE; DITHIZONE; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 3BETA; KERATINOCYTE GROWTH FACTOR; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 3; NOGGIN; NOTCH RECEPTOR; PANCREAS HORMONE; PROTEOGLYCAN; RETINOIC ACID; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR PDX 1; TRANSCRIPTION FACTOR SOX17; UNCLASSIFIED DRUG; VASCULOTROPIN; VIMENTIN; WNT3A PROTEIN; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL AGGREGATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; ENDOCRINE CELL; ENDODERM; FEMALE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; PANCREATIC ISLET LIKE THREE DIMENSIONAL AGGREGATE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL TRANSPLANTATION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; SULFATION; UPREGULATION; ANIMAL; CELL CULTURE TECHNIQUE; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; HUMAN EMBRYONIC STEM CELL; IMMUNOLOGY; PANCREAS ISLET; PHYSIOLOGY; TRANSPLANTATION;

ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINE; DIABETES MELLITUS, EXPERIMENTAL; ENDODERM; HUMAN EMBRYONIC STEM CELLS; HUMANS; HYPERGLYCEMIA; ISLETS OF LANGERHANS; MICE; STREPTOZOCIN;

EID: 84943261478     PISSN: 09636897     EISSN: 15553892     Source Type: Journal    
DOI: 10.3727/096368914X685438     Document Type: Article

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