-
1
-
-
4344693270
-
Biologists fear cloning hype will undermine stem-cell research
-
Knight, J. Biologists fear cloning hype will undermine stem-cell research. Nature 430, 817 (2004).
-
(2004)
Nature
, vol.430
, pp. 817
-
-
Knight, J.1
-
2
-
-
1842844414
-
Decreased β-cell mass in diabetes: Significance, mechanisms and therapeutic implications
-
Donath, M. Y. & Halban, P. A. Decreased β-cell mass in diabetes: Significance, mechanisms and therapeutic implications. Diabetologia 47, 581-589 (2004).
-
(2004)
Diabetologia
, vol.47
, pp. 581-589
-
-
Donath, M.Y.1
Halban, P.A.2
-
3
-
-
0036301577
-
Organogenesis: Pancreatic organogenesis developmental mechanisms and implications for therapy
-
Edlund, H. Organogenesis: Pancreatic organogenesis developmental mechanisms and implications for therapy. Nature Rev. Genet. 3, 524-532 (2002).
-
(2002)
Nature Rev. Genet.
, vol.3
, pp. 524-532
-
-
Edlund, H.1
-
4
-
-
0345687862
-
Genes, signals, and lineages in pancreas development
-
Murtaugh, L. C. & Melton, D. A. Genes, signals, and lineages in pancreas development. Annu. Rev. Cell Dev. Biol. 19, 71-89 (2003).
-
(2003)
Annu. Rev. Cell Dev. Biol.
, vol.19
, pp. 71-89
-
-
Murtaugh, L.C.1
Melton, D.A.2
-
5
-
-
2342477861
-
Navigating the pathway from embryonic stem cells to β cells
-
Stoffel, M., Vallier, L. & Pedersen, R. A. Navigating the pathway from embryonic stem cells to β cells. Semin. Cell Dev. Biol. 15, 327-336 (2004).
-
(2004)
Semin. Cell Dev. Biol.
, vol.15
, pp. 327-336
-
-
Stoffel, M.1
Vallier, L.2
Pedersen, R.A.3
-
6
-
-
2342505873
-
Making new β cells from stem cells
-
Colman, A. Making new β cells from stem cells. Semin. Cell Dev. Biol. 15, 337-345 (2004).
-
(2004)
Semin. Cell Dev. Biol.
, vol.15
, pp. 337-345
-
-
Colman, A.1
-
7
-
-
4544310572
-
In vitro directed differentiation of mouse embryonic stem cells into insulin-producing cells
-
Leon-Quinto, T., Jones, J., Skoudy, A., Burcin, M. & Soria, B. In vitro directed differentiation of mouse embryonic stem cells into insulin-producing cells. Diabetologia 47, 1442-1451 (2004).
-
(2004)
Diabetologia
, vol.47
, pp. 1442-1451
-
-
Leon-Quinto, T.1
Jones, J.2
Skoudy, A.3
Burcin, M.4
Soria, B.5
-
8
-
-
0017246625
-
Regeneration of islet cells
-
Hellerstrom, C., Andersson, A. & Gunnarsson, R. Regeneration of islet cells. Acta Endocrinol. Suppl. (Copenh.) 205, 145-160 (1976).
-
(1976)
Acta Endocrinol. Suppl. (Copenh.)
, vol.205
, pp. 145-160
-
-
Hellerstrom, C.1
Andersson, A.2
Gunnarsson, R.3
-
9
-
-
0034457490
-
Perspective: Postnatal pancreatic β cell growth
-
Bonner-Weir, S. Perspective: Postnatal pancreatic β cell growth. Endocrinology 141, 1926-1929 (2000).
-
(2000)
Endocrinology
, vol.141
, pp. 1926-1929
-
-
Bonner-Weir, S.1
-
10
-
-
0037219411
-
β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
-
Butler, A. E. et al. β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes. Diabetes 52, 102-110 (2003).
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
-
11
-
-
0033770540
-
Life and death of the pancreatic β cells
-
Bonner-Weir, S. Life and death of the pancreatic β cells. Trends Endocrinol. Metab. 11, 375-378 (2000).
-
(2000)
Trends Endocrinol. Metab.
, vol.11
, pp. 375-378
-
-
Bonner-Weir, S.1
-
12
-
-
0036070177
-
Pancreatic stem cells
-
Bonner-Weir, S. & Sharma, A. Pancreatic stem cells. J. Pathol. 197, 519-526 (2002).
-
(2002)
J. Pathol.
, vol.197
, pp. 519-526
-
-
Bonner-Weir, S.1
Sharma, A.2
-
13
-
-
0037364517
-
In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion
-
Ianus, A., Holz, G. G., Theise, N. D. & Hussain, M. A. In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. J. Clin. Invest. 111, 843-850 (2003).
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 843-850
-
-
Ianus, A.1
Holz, G.G.2
Theise, N.D.3
Hussain, M.A.4
-
14
-
-
1442354887
-
Extrapancreatic insulin-producing cells in multiple organs in diabetes
-
Kojima, H. et al. Extrapancreatic insulin-producing cells in multiple organs in diabetes. Proc. Natl Acad. Sci. USA 101, 2458-2463 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2458-2463
-
-
Kojima, H.1
-
15
-
-
1442326000
-
No evidence for significant transdifferentiation of bone marrow into pancreatic β-cells in vivo
-
Lechner, A. et al. No evidence for significant transdifferentiation of bone marrow into pancreatic β-cells in vivo. Diabetes 53, 616-623 (2004).
-
(2004)
Diabetes
, vol.53
, pp. 616-623
-
-
Lechner, A.1
-
16
-
-
0037820427
-
Bone marrow-derived stem cells initiate pancreatic regeneration
-
Hess, D. et al. Bone marrow-derived stem cells initiate pancreatic regeneration. Nature Biotechnol. 21, 763-770 (2003).
-
(2003)
Nature Biotechnol.
, vol.21
, pp. 763-770
-
-
Hess, D.1
-
17
-
-
2342510386
-
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
-
Dor, Y., Brown, J., Martinez, O. I. & Melton, D. A. Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429, 41-46 (2004).
-
(2004)
Nature
, vol.429
, pp. 41-46
-
-
Dor, Y.1
Brown, J.2
Martinez, O.I.3
Melton, D.A.4
-
18
-
-
4444320484
-
Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages
-
Sealberg, R. M. et al. Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages. Nature Biotechnol. 22, 1115-1124 (2004).
-
(2004)
Nature Biotechnol.
, vol.22
, pp. 1115-1124
-
-
Sealberg, R.M.1
-
19
-
-
0031841517
-
Extra-insular β cells associated with ductules are frequent in adult human pancreas
-
Bouwens, L. & Pipeleers, D. G. Extra-insular β cells associated with ductules are frequent in adult human pancreas. Diabetologia 41, 629-633 (1998).
-
(1998)
Diabetologia
, vol.41
, pp. 629-633
-
-
Bouwens, L.1
Pipeleers, D.G.2
-
20
-
-
0034608816
-
In vitro cultivation of human islets from expanded ductal tissue
-
Bonner-Weir, S. et al. In vitro cultivation of human islets from expanded ductal tissue. Proc. Natl Acad. Sci. USA 97, 7999-8004 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7999-8004
-
-
Bonner-Weir, S.1
-
21
-
-
0043268785
-
Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture
-
Gao, R. et al. Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture. Diabetes 52, 2007-2015 (2003).
-
(2003)
Diabetes
, vol.52
, pp. 2007-2015
-
-
Gao, R.1
-
22
-
-
0037191099
-
Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3
-
Heremans, Y. et al. Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3. J. Cell Biol. 159, 303-312 (2002).
-
(2002)
J. Cell Biol.
, vol.159
, pp. 303-312
-
-
Heremans, Y.1
-
23
-
-
0034068602
-
Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
-
Ferber, S. et al. Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. Nature Med. 6, 568-572 (2000).
-
(2000)
Nature Med.
, vol.6
, pp. 568-572
-
-
Ferber, S.1
-
24
-
-
0038472015
-
Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells
-
Zalzman, M. et al. Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells. Proc. Natl Acad. Sci. USA 100, 7253-7258 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7253-7258
-
-
Zalzman, M.1
-
25
-
-
2342614852
-
Engineering a new β-cell: A critical venture requiring special attention to constantly changing physiological needs
-
Kahn, S. E. Engineering a new β-cell: A critical venture requiring special attention to constantly changing physiological needs. Semin. Cell Dev. Biol. 15, 359-370 (2004).
-
(2004)
Semin. Cell Dev. Biol.
, vol.15
, pp. 359-370
-
-
Kahn, S.E.1
-
26
-
-
0035491791
-
Gene and cell-replacement therapy in the treatment of type 1 diabetes: How high must the standards be set?
-
Hallban, P. A., Kahn, S. E., Lernmark, A. & Rhodes, C. J. Gene and cell-replacement therapy in the treatment of type 1 diabetes: How high must the standards be set? Diabetes 50, 2181-2191 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 2181-2191
-
-
Hallban, P.A.1
Kahn, S.E.2
Lernmark, A.3
Rhodes, C.J.4
-
27
-
-
0020069732
-
Macro and micro-domains in the endocrine pancreas
-
Orci, L. Macro and micro-domains in the endocrine pancreas. Diabetes 31, 538-565 (1982).
-
(1982)
Diabetes
, vol.31
, pp. 538-565
-
-
Orci, L.1
-
28
-
-
2342519447
-
Can we make surrogate β-cells better than the original?
-
Weir, G. C. Can we make surrogate β-cells better than the original? Semin. Cell Dev. Biol. 15, 347-357 (2004).
-
(2004)
Semin. Cell Dev. Biol.
, vol.15
, pp. 347-357
-
-
Weir, G.C.1
-
29
-
-
0021254228
-
The mechanism of insulin secretion
-
Howell, S. L. The mechanism of insulin secretion. Diabetologia 26, 319-327 (1984).
-
(1984)
Diabetologia
, vol.26
, pp. 319-327
-
-
Howell, S.L.1
|