Phytochemical Indicaxanthin Inhibits Colon Cancer Cell Growth and Affects the DNA Methylation Status by Influencing Epigenetically Modifying Enzyme Expression and Activity

Journal of Nutrigenetics and Nutrigenomics

Volumn 8, Issue 3, 2015, Pages 114-127

  Naselli, Flores ^a   Belshaw, Nigel Junior ^b   Gentile, Carla ^a   Tutone, Marco ^a   Tesoriere, Luisa ^a   Livrea, Maria Antonietta ^a   Caradonna, Fabio ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b INSTITUTE OF FOOD RESEARCH   (United Kingdom)

Author keywords

Betalains; Chemoprevention; Colorectal cancer; DNA methyltransferase; Epigenetics; Indicaxanthin; Molecular modeling; Phytochemicals

Indexed keywords

DNA METHYLTRANSFERASE 1; INDICAXANTHIN; PLANT MEDICINAL PRODUCT; UNCLASSIFIED DRUG; BETAXANTHIN; PYRIDINE DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER PREVENTION; CELL PROLIFERATION; CELL VIABILITY; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; COMPUTER MODEL; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEMETHYLATION; DNA METHYLATION; DRUG MECHANISM; DRUG PROTEIN BINDING; ENZYME ACTIVITY; ENZYME INHIBITION; EPIGENETICS; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR MODEL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TUMOR GROWTH; COLON TUMOR; DRUG EFFECTS; GENETIC EPIGENESIS; GENETICS; PATHOLOGY; TUMOR CELL LINE;

BETAXANTHINS; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; DNA METHYLATION; EPIGENESIS, GENETIC; HUMANS; PYRIDINES;

EID: 84943253892     PISSN: 16616499     EISSN: 16616758     Source Type: Journal    
DOI: 10.1159/000439382     Document Type: Article

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