Plasma HMGB-1 levels in subjects with obesity and type 2 diabetes: A cross-sectional study in China

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Wang, Hang ^a   Qu, Hua ^a   Deng, Huacong ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HIGH MOBILITY GROUP B1 PROTEIN; INSULIN; INTERLEUKIN 6; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; BIOLOGICAL MARKER; HMGB1 PROTEIN, HUMAN;

ADULT; AGE; AGED; ARTICLE; BLOOD PRESSURE; BODY FAT; BODY HEIGHT; BODY MASS; BODY WEIGHT; CHINA; CHINESE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS-SECTIONAL STUDY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HIP CIRCUMFERENCE; HOMEOSTASIS; HUMAN; INFLAMMATION; INSULIN RESISTANCE; LIPID ANALYSIS; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PATHOGENESIS; PROTEIN BLOOD LEVEL; SEX; WAIST CIRCUMFERENCE; WAIST HIP RATIO; BLOOD; MIDDLE AGED; PATHOLOGY;

AGED; BIOMARKERS; DIABETES MELLITUS, TYPE 2; FEMALE; HMGB1 PROTEIN; HUMANS; MALE; MIDDLE AGED; OBESITY;

EID: 84943231922     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0136564     Document Type: Article

References (36)

1. Czura C J, Tracey K J. Targeting high mobility group box 1 as a late-acting mediator of inflammation[J]. Crit Care Med, 2003, 31(1):46-50.
2. James Harwood H. Jr. The adipocy te as an endocrine organ in the regulation of metabolic homeostasis. Neuropharmacology. 2012 Jul; 63(1):57-75. doi: 10.1016/j.neuropharm.2011.12.010 PMID: 22200617
3. Unger R H. Longevity, lipotoxicity and leptin: the adipocyte defense against feasting and famine[J]. Biochimie, 2005, 87(1):57-64. PMID: 15733738
4. Arrigo T, Chirico V, Salpietro V, Munafò C, Ferraù V, Gitto E, et al. High-mobility group protein B1: a new biomarker of metabolic syndrome in obese children. Eur J Endocrinol. 2013 Mar. 15; 168(4):631-8. doi: 10.1530/EJE-13-0037 PMID: 23384711
5. World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications, Report of a WHO Consultation. Part 1. Diagnosis and classification of diabetes mellitus. Geneva: Department of Noncommunicable Disease Surveillance; 1999, WHO/NCD/NCS/99.2.
6. The Asia-Pacific perspective: redefining obesity and its treatment. Health Communications Australia Pty Ltd; 2000, WHO/IASO/IOTF.
7. Bianchi M E, Beltrame M, Paonessa G. Specific recognition of cruciform DNA by nuclear protein HMG1 [J]. Science, 1989, 24(4894):1056-1059.
8. Javaherian K, Liu J F, Wang J C. Nonhistone proteins HMG1 and HMG2 change the DNA helical structure[J]. Science, 1978, 199(4335):1345-1346. PMID: 628842
9. Pasqualini JR, Sterner R, Mercat P and Allfrey VG. Estradiol enhanced acetylation of nuclear high mobility group proteins of the uterus of newborn guinea pigs. Biochem. Biophys. Res. Commun. 161, 1260-1266 (1989). PMID: 2742588
10. Zhang CC, Krieg S and Shapiro DJ. HMG-1 stimulates estrogen response element binding by estrogen receptor from stably transfected HeLa cells. Mol. Endocrinol. 13, 632-643 (1999). PMID: 10194768
11. Ciubotaru M and Schatz DG. Synapsis of recombination signal sequences located in cis and DNA underwinding in V (D) J recombination. Mol. Cell. Biol. 24, 8727-8744 (2004). PMID: 15367690
12. Stros M, Ozaki T, Bacikova A, Kageyama H and Nakagawara A. HMGB1 and HMGB2 cell-specifically down-regulate the p53- and p73-dependent sequencespecific transactivation from the human Bax gene promoter. J. Biol. Chem. 277, 7157-7164 (2002). PMID: 11748232
13. Stros M, Muselikova-Polanska E, Pospisilova S and Strauss F. High-affinity binding of tumor-suppressor protein p53 and HMGB1 to hemicatenated DNA loops. Biochemistry 43, 7215-7225 (2004). PMID: 15170359
14. Wang H, Bloom O, Zhang M, Vishnubhakat JM, Ombrellino M, Che J. HMG-1 as a late mediator of endotoxin lethality in mice. Science. 1999 Jul. 9; 285(5425):248-51. PMID: 10398600
15. Hori O, Brett J, Slattery T, Cao R, Zhang J, Chen JX. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J Biol Chem. 1995 Oct. 27; 270(43):25752-61. PMID: 7592757
16. Huttunen HJ, Fages C, Kuja-Panula J, Ridley AJ, Rauvala H. Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis. Cancer Res. 2002 Aug. 15; 62(16):4805-11. PMID: 12183440
17. Van Beijnum JR, Buurman WA, Griffioen AW. Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1). Angiogenesis. 2008;11(1):91-9. doi: 10.1007/s10456-008-9093-5 PMID: 18264787
18. Yan SD, Schmidt AM, Anderson GM, Zhang J, Brett J, Zou YS, et al. Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins. J Biol Chem. 1994 Apr. 1; 269(13):9889-97. PMID: 8144582
19. Yang H, Wang H, Czura CJ, Tracey KJ. The cytokine activity of HMGB1. J Leukoc Biol. 2005 Jul; 78(1):1-8. PMID: 15734795
20. Park JS, Arcaroli J, Yum HK, Yang H, Wang H, Yang KY, et al. Activation of gene expression in human neutrophils by high mobility group box 1 protein. Am J Physiol Cell Physiol. 2003 Apr; 284(4):C870.9. PMID: 12620891
21. Nativel B, Marimoutou M, Thon-Hon VG, Gunasekaran MK, Andries J, Stanislas G. Soluble HMGB1 is a novel adipokine stimulating IL-6 secretion through RAGE receptor in SW872 preadipocyte cell line: contribution to chronic inflammation in fat tissue. PLoS One. 2013 Sep. 20; 8(9):e76039. doi: 10.1371/journal.pone.0076039 PMID: 24073286
22. Kim JH, Bachmann RA, Chen J. Interleukin-6 and insulin resistance. Vitam Horm. 2009;80:613-33. doi: 10.1016/S0083-6729 (08) 00621-3 PMID: 19251052
23. Devaraj S, Dasu MR, Rockwood J, Winter W, Griffen SC, Jialal I. Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state. J Clin Endocrinol Metab. 2008 Feb; 93(2):578-83. PMID: 18029454
24. Dasu MR, Devaraj S, Park S, Jialal I. Increased toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects. Diabetes Care. 2010 Apr; 33(4):861-8. doi: 10.2337/dc09-1799 PMID: 20067962
25. Gunasekaran MK, Viranaicken W, Girard AC, Festy F, Cesari M, Roche R, et al. Inflammation triggers high mobility group box 1 (HMGB1) secretion in adipose tissue, a potential link to obesity. Cytokine. 2013 Oct; 64(1):103-11. doi: 10.1016/j.cyto.2013.07.017 PMID: 23938155
26. Fasshauer M, Klein J, Neumann S, Eszlinger M, Paschke R. Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes. Biochem Biophys Res Commun 2002;290:1084-9. PMID: 11798186
27. Simons PJ, Van Den Pangaart PS, Aerts JM, Boon L. Pro-inflammatory delipidizing cytokines reduce adiponectin secretion from human adipocytes without affecting adiponectin oligomerization. J Endocrinol. 2007;192:289-99. PMID: 17283229
28. Tan BK, Adya R, Farhatullah S, Lewandowski KC, O'Hare P, Lehnert H. Omentin-1, a novel adipokine, is decreased in overweight insulin-resistant women with polycystic ovary syndrome: ex vivo and in vivo regulation of omentin 1 by insulin and glucose. Diabetes 2008;57:801-8. doi: 10.2337/db07-0990 PMID: 18174521
29. Kralisch S, Klein J, Lossner U, Bluher M, Paschke R, Stumvoll M, et al. Interleukin-6 is a negative regulator of visfatin gene expression in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab 2005;289:E586.90. PMID: 15899942
30. Guzman-Ruiz R, Ortega F, Rodriguez A, Vazquez-Martinez R, Diaz-Ruiz A, Garcia-Navarro S. Alarmin high-mobility group B1 (HMGB1) is regulated in human adipocytes in insulin resistance and influences insulin secretion in β-cells. Int J Obes (Lond). 2014 Dec; 38(12):1545-54.
31. Ni XR, Sun ZJ, Hu GH, Wang RH. High Concentration of Insulin Promotes Apoptosis of Primary Cultured Rat Ovarian Granulosa Cells Via Its Increase in Extracellular HMGB1. Reprod Sci. 2015 Mar; 22(3):271-7. doi: 10.1177/1933719114549852 PMID: 25228632
32. Lee BW1, Chae HY, Kwon SJ, Park SY, Ihm J, Ihm SH. RAGE ligands induce apoptotic cell death of pancreatic β-cells via oxidative stress. Int J Mol Med. 2010 Dec; 26(6):813-8. PMID: 21042774
33. Jin D, Wu Y, Zhao L, Guo J, Zhang K, Chen Z. Atorvastatin reduces serum HMGB1 levels in patients with hyperlipidemia. Exp Ther Med. 2012 Dec; 4(6):1124-1126. PMID: 23226786
34. Andersson U, Tracey KJ. HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol. 2011;29:139-62. doi: 10.1146/annurev-immunol-030409-101323 PMID: 21219181
35. Schierbeck H, Wahamaa H, Andersson U, Harris HE. Immunomodulatory drugs regulate HMGB1 release from activated human monocytes. Mol Med. 2010 Sep-Oct; 16(9-10):343-51. doi: 10.2119/molmed.2010.00031 PMID: 20386869
36. Gero D, Szoleczky P, Modis K, Pribis JP, Al-Abed Y, Yang H. Identification of pharmacological modulators of HMGB1-induced inflammatory response by cell-based screening. PLoS One. 2013 Jun. 14; 8(6):e65994. doi: 10.1371/journal.pone.0065994 PMID: 23799067