-
1
-
-
56249083570
-
Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD
-
Mannino DM, Thorn D, Swensen A, et al. Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD. Eur Respir J 2008; 32: 962-969.
-
(2008)
Eur Respir J
, vol.32
, pp. 962-969
-
-
Mannino, D.M.1
Thorn, D.2
Swensen, A.3
-
2
-
-
84873956600
-
Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease, GOLD executive summary
-
Vestbo J, Hurd SS, Agusti AG, et al. Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease, GOLD Executive Summary. Am J Respir Crit Care Med 2013; 187: 347-365.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 347-365
-
-
Vestbo, J.1
Hurd, S.S.2
Agusti, A.G.3
-
3
-
-
84875847989
-
Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease
-
Vanfleteren LE, Spruit MA, Groenen M, et al. Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2013; 187: 728-735.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 728-735
-
-
Vanfleteren, L.E.1
Spruit, M.A.2
Groenen, M.3
-
4
-
-
84880040954
-
Chronic obstructive pulmonary disease and comorbidities
-
Decramer M, Janssens W. Chronic obstructive pulmonary disease and comorbidities. Lancet Respir Med 2013; 1: 73-83.
-
(2013)
Lancet Respir Med
, vol.1
, pp. 73-83
-
-
Decramer, M.1
Janssens, W.2
-
5
-
-
84883053051
-
Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort
-
Miller J, Edwards LD, Agusti A, et al. Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort. Respir Med 2013; 107: 1376-1384.
-
(2013)
Respir Med
, vol.107
, pp. 1376-1384
-
-
Miller, J.1
Edwards, L.D.2
Agusti, A.3
-
6
-
-
84922393620
-
Network analysis in the investigation of chronic respiratory diseases: From basics to application
-
Diez D, Agusti A, Wheelock CE. Network analysis in the investigation of chronic respiratory diseases: from basics to application. Am J Respir Crit Care Med 2014; 190: 981-988.
-
(2014)
Am J Respir Crit Care Med
, vol.190
, pp. 981-988
-
-
Diez, D.1
Agusti, A.2
Wheelock, C.E.3
-
7
-
-
84907211818
-
Network medicine, multimorbidity and the lung in the elderly
-
Faner R, Cruz T, López-Giraldo A, et al. Network medicine, multimorbidity and the lung in the elderly. Eur Respir J 2014; 44: 775-788.
-
(2014)
Eur Respir J
, vol.44
, pp. 775-788
-
-
Faner, R.1
Cruz, T.2
López-Giraldo, A.3
-
9
-
-
84890467491
-
Phenotypes and disease characterization in chronic obstructive pulmonary disease. Toward the extinction of phenotypes?
-
Agusti A. Phenotypes and disease characterization in chronic obstructive pulmonary disease. toward the extinction of phenotypes? Ann Am Thorac Soc 2013; 10: Suppl., S125-S130.
-
(2013)
Ann Am Thorac Soc
, vol.10
, pp. S125-S130
-
-
Agusti, A.1
-
10
-
-
84891845870
-
Risk factors and comorbidities in the preclinical stages of chronic obstructive pulmonary disease
-
Van Remoortel H, Hornikx M, Langer D, et al. Risk factors and comorbidities in the preclinical stages of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2013; 189: 30-38.
-
(2013)
Am J Respir Crit Care Med
, vol.189
, pp. 30-38
-
-
Van Remoortel, H.1
Hornikx, M.2
Langer, D.3
-
12
-
-
84942762298
-
Network analysis: A way forward to understand COPD multimorbidity
-
Faner R, Agusti A. Network analysis: a way forward to understand COPD multimorbidity. Eur Respir J 2015; 46: 591-592.
-
(2015)
Eur Respir J
, vol.46
, pp. 591-592
-
-
Faner, R.1
Agusti, A.2
-
13
-
-
84907400402
-
Network medicine analysis of COPD multimorbidities
-
Grosdidier S, Ferrer A, Faner R, et al. Network medicine analysis of COPD multimorbidities. Respir Res 2014; 15: 111.
-
(2014)
Respir Res
, vol.15
, pp. 111
-
-
Grosdidier, S.1
Ferrer, A.2
Faner, R.3
-
14
-
-
77954086131
-
Auditoria clinica de los pacientes hospitalizados por exacerbacion de EPOC en Espana (estudio AUDIPOC): metodo y organizacion del trabajo
-
Pozo-Rodriguez F, Alvarez CJ, Castro-Acosta A, et al. Auditoria clinica de los pacientes hospitalizados por exacerbacion de EPOC en Espana (estudio AUDIPOC): metodo y organizacion del trabajo [Clinical audit of patients admitted to hospital in Spain due to exacerbation of COPD (AUDIPOC study): method and organisation]. Arch Bronconeumol 2010; 46: 349-357.
-
(2010)
Arch Bronconeumol
, vol.46
, pp. 349-357
-
-
Pozo-Rodriguez, F.1
Alvarez, C.J.2
Castro-Acosta, A.3
-
15
-
-
84864460763
-
Clinical audit of COPD patients requiring hospital admissions in Spain: AUDIPOC Study
-
Pozo-Rodriguez F, López-Campos JL, Alvarez-Martínez CJ, et al. Clinical audit of COPD patients requiring hospital admissions in Spain: AUDIPOC Study. PLoS ONE 2012; 7: e42156.
-
(2012)
PLoS ONE
, vol.7
, pp. e42156
-
-
Pozo-Rodriguez, F.1
López-Campos, J.L.2
Alvarez-Martínez, C.J.3
-
16
-
-
84873370840
-
European COPD Audit: Design, organisation of work and methodology
-
Lopez-Campos JL, Hartl S, Pozo-Rodriguez F, et al. European COPD Audit: design, organisation of work and methodology. Eur Respir J 2013; 41: 270-276.
-
(2013)
Eur Respir J
, vol.41
, pp. 270-276
-
-
Lopez-Campos, J.L.1
Hartl, S.2
Pozo-Rodriguez, F.3
-
17
-
-
84895533791
-
Variability of hospital resources for acute care of COPD patients: The European COPD Audit
-
Lopez-Campos JL, Hartl S, Pozo-Rodriguez F, et al. Variability of hospital resources for acute care of COPD patients: the European COPD Audit. Eur Respir J 2014; 43: 754-762.
-
(2014)
Eur Respir J
, vol.43
, pp. 754-762
-
-
Lopez-Campos, J.L.1
Hartl, S.2
Pozo-Rodriguez, F.3
-
18
-
-
66249129037
-
A dynamic network approach for the study of human phenotypes
-
Hidalgo CA, Blumm N, Barabasi AL, et al. A dynamic network approach for the study of human phenotypes. PLoS Comput Biol 2009; 5: e1000353.
-
(2009)
PLoS Comput Biol
, vol.5
, pp. e1000353
-
-
Hidalgo, C.A.1
Blumm, N.2
Barabasi, A.L.3
-
20
-
-
0242490780
-
Cytoscape: A software environment for integrated models of biomolecular interaction networks
-
Shannon P, Markiel A, Ozier O, et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 2003; 13: 2498-2504.
-
(2003)
Genome Res
, vol.13
, pp. 2498-2504
-
-
Shannon, P.1
Markiel, A.2
Ozier, O.3
-
21
-
-
78149236787
-
DisGeNET: A Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks
-
Bauer-Mehren A, Rautschka M, Sanz F, et al. DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks. Bioinformatics 2010; 26: 2924-2926.
-
(2010)
Bioinformatics
, vol.26
, pp. 2924-2926
-
-
Bauer-Mehren, A.1
Rautschka, M.2
Sanz, F.3
-
22
-
-
84939221315
-
DisGeNET: A discovery platform for the dynamical exploration of human diseases and their genes
-
Pinero J, Queralt-Rosinach N, Bravo A, et al. DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes. Database (Oxford) 2015; 2015: bav028.
-
(2015)
Database (Oxford)
, vol.2015
, pp. bav028
-
-
Pinero, J.1
Queralt-Rosinach, N.2
Bravo, A.3
-
23
-
-
78650373804
-
Network medicine: A network-based approach to human disease
-
Barabasi AL, Gulbahce N, Loscalzo J. Network medicine: a network-based approach to human disease. Nat Rev Genet 2011; 12: 56-68.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 56-68
-
-
Barabasi, A.L.1
Gulbahce, N.2
Loscalzo, J.3
-
24
-
-
84856918212
-
HIPPIE: Integrating protein interaction networks with experiment based quality scores
-
Schaefer MH, Fontaine JF, Vinayagam A, et al. HIPPIE: Integrating protein interaction networks with experiment based quality scores. PLoS ONE 2012; 7: e31826.
-
(2012)
PLoS ONE
, vol.7
, pp. e31826
-
-
Schaefer, M.H.1
Fontaine, J.F.2
Vinayagam, A.3
-
25
-
-
77954275723
-
ToppCluster: A multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems
-
Kaimal V, Bardes EE, Tabar SC, et al. ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems. Nucleic Acids Res 2010; 38: W96-W102.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. W96-W102
-
-
Kaimal, V.1
Bardes, E.E.2
Tabar, S.C.3
-
26
-
-
79551603829
-
Characterisation of COPD heterogeneity in the ECLIPSE cohort
-
Agusti A, Calverley P, Celli B, et al. Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res 2010; 11: 122-136.
-
(2010)
Respir Res
, vol.11
, pp. 122-136
-
-
Agusti, A.1
Calverley, P.2
Celli, B.3
-
27
-
-
84863952703
-
Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease
-
Divo M, Cote C, de Torres JP, et al. Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012; 186: 155-161.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 155-161
-
-
Divo, M.1
Cote, C.2
De Torres, J.P.3
-
28
-
-
84903398807
-
Targeting IL-1beta and IL-17A driven inflammation during influenza-induced exacerbations of chronic lung inflammation
-
Sichelstiel A, Yadava K, Trompette A, et al. Targeting IL-1beta and IL-17A driven inflammation during influenza-induced exacerbations of chronic lung inflammation. PLoS ONE 2014; 9: e98440.
-
(2014)
PLoS ONE
, vol.9
, pp. e98440
-
-
Sichelstiel, A.1
Yadava, K.2
Trompette, A.3
-
29
-
-
84863732490
-
Role of P2X7 receptors in release of IL-1beta: A possible mediator of pulmonary inflammation
-
Mortaz E, Adcock IM, Shafei H, et al. Role of P2X7 receptors in release of IL-1beta: a possible mediator of pulmonary inflammation. Tanaffos 2012; 11: 6-11.
-
(2012)
Tanaffos
, vol.11
, pp. 6-11
-
-
Mortaz, E.1
Adcock, I.M.2
Shafei, H.3
-
30
-
-
84876578788
-
Adhesion molecules, endothelin-1 and lung function in seven population-based cohorts
-
Oelsner EC, Pottinger TD, Burkart KM, et al. Adhesion molecules, endothelin-1 and lung function in seven population-based cohorts. Biomarkers 2013; 18: 196-203.
-
(2013)
Biomarkers
, vol.18
, pp. 196-203
-
-
Oelsner, E.C.1
Pottinger, T.D.2
Burkart, K.M.3
-
31
-
-
53949117573
-
Exhaled and arterial levels of endothelin-1 are increased and correlate with pulmonary systolic pressure in COPD with pulmonary hypertension
-
Carratu P, Scoditti C, Maniscalco M, et al. Exhaled and arterial levels of endothelin-1 are increased and correlate with pulmonary systolic pressure in COPD with pulmonary hypertension. BMC Pulm Med 2008; 8: 20.
-
(2008)
BMC Pulm Med
, vol.8
, pp. 20
-
-
Carratu, P.1
Scoditti, C.2
Maniscalco, M.3
-
32
-
-
0043133463
-
Endothelin-1 levels in the pathophysiology of chronic obstructive pulmonary disease and bronchial asthma
-
Spiropoulos K, Trakada G, Nikolaou E, et al. Endothelin-1 levels in the pathophysiology of chronic obstructive pulmonary disease and bronchial asthma. Respir Med 2003; 97: 983-989.
-
(2003)
Respir Med
, vol.97
, pp. 983-989
-
-
Spiropoulos, K.1
Trakada, G.2
Nikolaou, E.3
-
33
-
-
84898728936
-
Rapid FEV1 decline, early COPD, and angiotensin-converting enzymes?
-
Wedzicha JA, Donaldson GC. Rapid FEV1 decline, early COPD, and angiotensin-converting enzymes? Chest 2014; 145: 671-672.
-
(2014)
Chest
, vol.145
, pp. 671-672
-
-
Wedzicha, J.A.1
Donaldson, G.C.2
-
34
-
-
84898734234
-
Rapid lung function decline in smokers is a risk factor for COPD and is attenuated by angiotensin-converting enzyme inhibitor use
-
Petersen H, Sood A, Meek PM, et al. Rapid lung function decline in smokers is a risk factor for COPD and is attenuated by angiotensin-converting enzyme inhibitor use. Chest 2014; 145: 695-703.
-
(2014)
Chest
, vol.145
, pp. 695-703
-
-
Petersen, H.1
Sood, A.2
Meek, P.M.3
-
35
-
-
84890506487
-
Lungs, bone marrow and adipose tissue: A network approach to the pathobiology of chronic obstructive pulmonary disease
-
Agusti A, Barbera JA, Wouters EF, et al. Lungs, bone marrow and adipose tissue: a network approach to the pathobiology of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2013; 188: 1396-1406.
-
(2013)
Am J Respir Crit Care Med
, vol.188
, pp. 1396-1406
-
-
Agusti, A.1
Barbera, J.A.2
Wouters, E.F.3
-
36
-
-
84876485451
-
Mechanisms of acute exacerbation of respiratory symptoms in chronic obstructive pulmonary disease
-
Roca M, Verduri A, Corbetta L, et al. Mechanisms of acute exacerbation of respiratory symptoms in chronic obstructive pulmonary disease. Eur J Clin Invest 2013; 43: 510-521.
-
(2013)
Eur J Clin Invest
, vol.43
, pp. 510-521
-
-
Roca, M.1
Verduri, A.2
Corbetta, L.3
-
37
-
-
84860483262
-
Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD
-
McAllister DA, Maclay JD, Mills NL, et al. Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD. Eur Respir J 2012; 39: 1097-1103.
-
(2012)
Eur Respir J
, vol.39
, pp. 1097-1103
-
-
McAllister, D.A.1
Maclay, J.D.2
Mills, N.L.3
-
38
-
-
79952201056
-
Knowledge management for systems biology a general and visually driven framework applied to translational medicine
-
Maier D, Kalus W, Wolff M, et al. Knowledge management for systems biology a general and visually driven framework applied to translational medicine. BMC Syst Biol 2011; 5: 38.
-
(2011)
BMC Syst Biol
, vol.5
, pp. 38
-
-
Maier, D.1
Kalus, W.2
Wolff, M.3
-
40
-
-
84873390590
-
"Drivers" of translational cancer epidemiology in the 21st century: Needs and opportunities
-
Lam TK, Spitz M, Schully SD, et al. "Drivers" of translational cancer epidemiology in the 21st century: needs and opportunities. Cancer Epidemiol Biomarkers Prev 2013; 22: 181-188.
-
(2013)
Cancer Epidemiol Biomarkers Prev
, vol.22
, pp. 181-188
-
-
Lam, T.K.1
Spitz, M.2
Schully, S.D.3
-
41
-
-
70350435758
-
Myocardial infarction, peptic ulcer and acetylsalicylic acid: Of good and evil
-
Marshall JK. Myocardial infarction, peptic ulcer and acetylsalicylic acid: of good and evil. Can J Gastroenterol 2009; 23: 618.
-
(2009)
Can J Gastroenterol
, vol.23
, pp. 618
-
-
Marshall, J.K.1
-
42
-
-
84865121012
-
Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis
-
Faner R, Rojas M, MacNee W, et al. Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2012; 186: 306-313.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 306-313
-
-
Faner, R.1
Rojas, M.2
MacNee, W.3
-
44
-
-
84896273713
-
Identification of clinical phenotypes using cluster analyses in COPD patients with multiple comorbidities
-
Burgel PR, Paillasseur JL, Roche N. Identification of clinical phenotypes using cluster analyses in COPD patients with multiple comorbidities. Biomed Res Int 2014; 2014: 420134.
-
(2014)
Biomed Res Int
, vol.2014
, pp. 420134
-
-
Burgel, P.R.1
Paillasseur, J.L.2
Roche, N.3
-
45
-
-
34547146985
-
Network medicine - From obesity to the "diseasome"
-
Barabasi AL. Network medicine - from obesity to the "diseasome". N Engl J Med 2007; 357: 404-407.
-
(2007)
N Engl J Med
, vol.357
, pp. 404-407
-
-
Barabasi, A.L.1
-
46
-
-
79955498646
-
Addressing the complexity of chronic obstructive pulmonary disease: From phenotypes and biomarkers to scale-free networks, systems biology, and P4 medicine
-
Agusti A, Sobradillo P, Celli B. Addressing the complexity of chronic obstructive pulmonary disease: from phenotypes and biomarkers to scale-free networks, systems biology, and P4 medicine. Am J Respir Crit Care Med 2011; 183: 1129-1137.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 1129-1137
-
-
Agusti, A.1
Sobradillo, P.2
Celli, B.3
-
47
-
-
84905964581
-
The path to personalized medicine in COPD
-
Agusti A. The path to personalized medicine in COPD. Thorax 2014; 69: 857-864.
-
(2014)
Thorax
, vol.69
, pp. 857-864
-
-
Agusti, A.1
-
48
-
-
84902864437
-
Five comorbidities reflected the health status in patients with chronic obstructive pulmonary disease: The newly developed COMCOLD index
-
Frei A, Muggensturm P, Putcha N, et al. Five comorbidities reflected the health status in patients with chronic obstructive pulmonary disease: the newly developed COMCOLD index. J Clin Epidemiol 2014; 67: 904-911.
-
(2014)
J Clin Epidemiol
, vol.67
, pp. 904-911
-
-
Frei, A.1
Muggensturm, P.2
Putcha, N.3
-
49
-
-
84901313491
-
Systemic inflammatory response to smoking in chronic obstructive pulmonary disease: Evidence of a gender effect
-
Faner R, Gonzalez N, Cruz T, et al. Systemic inflammatory response to smoking in chronic obstructive pulmonary disease: evidence of a gender effect. PLoS ONE 2014; 9: e97491.
-
(2014)
PLoS ONE
, vol.9
, pp. e97491
-
-
Faner, R.1
Gonzalez, N.2
Cruz, T.3
-
50
-
-
84922895251
-
Personalized respiratory medicine: Exploring the horizon, addressing the issues
-
Agusti A, Anto JM, Auffray C, et al. Personalized respiratory medicine: exploring the horizon, addressing the issues. Am J Respir Crit Care Med 2015; 191: 391-401.
-
(2015)
Am J Respir Crit Care Med
, vol.191
, pp. 391-401
-
-
Agusti, A.1
Anto, J.M.2
Auffray, C.3
|