메뉴 건너뛰기




Volumn 24, Issue 6, 2015, Pages 470-483

Association of APC, GSTP1 and SOCS1 promoter methylation with the risk of hepatocellular carcinoma: A meta-analysis

Author keywords

APC; GSTP1; hepatocellular carcinoma; meta analysis; promoter methylation; SOCS1

Indexed keywords

APC PROTEIN; GLUTATHIONE TRANSFERASE P1; SUPPRESSOR OF CYTOKINE SIGNALING 1; APC PROTEIN, HUMAN; GSTP1 PROTEIN, HUMAN; SOCS1 PROTEIN, HUMAN; SUPPRESSOR OF CYTOKINE SIGNALING;

EID: 84943153918     PISSN: 09598278     EISSN: 14735709     Source Type: Journal    
DOI: 10.1097/CEJ.0000000000000121     Document Type: Article
Times cited : (23)

References (51)
  • 1
    • 33750364352 scopus 로고    scopus 로고
    • Association of GSTP1 CpG islands hypermethylation with poor prognosis in human breast cancers
    • Arai T, Miyoshi Y, Kim SJ, Taguchi T, Tamaki Y, Noguchi S (2006). Association of GSTP1 CpG islands hypermethylation with poor prognosis in human breast cancers. Breast Cancer Res Treat 100:169-176.
    • (2006) Breast Cancer Res Treat , vol.100 , pp. 169-176
    • Arai, T.1    Miyoshi, Y.2    Kim, S.J.3    Taguchi, T.4    Tamaki, Y.5    Noguchi, S.6
  • 2
    • 0037151042 scopus 로고    scopus 로고
    • Methyl-CpG binding domain protein 2 represses transcription from hypermethylated pi-class glutathione S-transferase gene promoters in hepatocellular carcinoma cells
    • Bakker J, Lin X, Nelson WG (2002). Methyl-CpG binding domain protein 2 represses transcription from hypermethylated pi-class glutathione S-transferase gene promoters in hepatocellular carcinoma cells. J Biol Chem 277:22573-22580.
    • (2002) J Biol Chem , vol.277 , pp. 22573-22580
    • Bakker, J.1    Lin, X.2    Nelson, W.G.3
  • 3
    • 31344466008 scopus 로고    scopus 로고
    • DNA methylation and gene silencing in cancer
    • Baylin SB (2005). DNA methylation and gene silencing in cancer. Nat Clin Pract Oncol 2 (Suppl 1):S4-S11.
    • (2005) Nat Clin Pract Oncol , vol.2 , pp. S4-S11
    • Baylin, S.B.1
  • 4
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • Begg CB, Mazumdar M (1994). Operating characteristics of a rank correlation test for publication bias. Biometrics 50:1088-1101.
    • (1994) Biometrics , vol.50 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2
  • 7
    • 84879596104 scopus 로고    scopus 로고
    • A trivial role of STAT4 variant in chronic hepatitis B induced hepatocellular carcinoma
    • Clark A, Gerlach F, Hv Tong, Hoan NX, Song le H, Toan NL, et al. (2013). A trivial role of STAT4 variant in chronic hepatitis B induced hepatocellular carcinoma. Infect Genet Evol 18:257-261.
    • (2013) Infect Genet Evol , vol.18 , pp. 257-261
    • Clark, A.1    Gerlach, F.2    Tong, H.3    Hoan, N.X.4    Le Song, H.5    Toan, N.L.6
  • 8
    • 0142012164 scopus 로고    scopus 로고
    • Detoxification of electrophilic compounds by glutathione S-transferase catalysis: Determinants of individual response to chemical carcinogens and chemotherapeutic drugs?
    • Coles BF, Kadlubar FF (2003). Detoxification of electrophilic compounds by glutathione S-transferase catalysis: determinants of individual response to chemical carcinogens and chemotherapeutic drugs? Biofactors 17:115-130.
    • (2003) Biofactors , vol.17 , pp. 115-130
    • Coles, B.F.1    Kadlubar, F.F.2
  • 10
    • 16544389958 scopus 로고    scopus 로고
    • Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor
    • Deng G, Song GA, Pong E, Sleisenger M, Kim YS (2004). Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor. Cancer Res 64:2692-2698.
    • (2004) Cancer Res , vol.64 , pp. 2692-2698
    • Deng, G.1    Song, G.A.2    Pong, E.3    Sleisenger, M.4    Kim, Y.S.5
  • 11
    • 16544395591 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • Das PM, Singal R (2004). DNA methylation and cancer. J Clin Oncol 22:4632-4642.
    • (2004) J Clin Oncol , vol.22 , pp. 4632-4642
    • Das, P.M.1    Singal, R.2
  • 12
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C (1997). Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629-634.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 13
    • 77950628676 scopus 로고    scopus 로고
    • DNA methylation changes in normal liver tissues and hepatocellular carcinoma with different viral infection
    • Feng Q, Stern JE, Hawes SE, Lu H, Jiang M, Kiviat NB (2010). DNA methylation changes in normal liver tissues and hepatocellular carcinoma with different viral infection. Exp Mol Pathol 88:287-292.
    • (2010) Exp Mol Pathol , vol.88 , pp. 287-292
    • Feng, Q.1    Stern, J.E.2    Hawes, S.E.3    Lu, H.4    Jiang, M.5    Kiviat, N.B.6
  • 14
    • 77957149560 scopus 로고    scopus 로고
    • Comparative analysis of promoter methylation and gene expression endpoints between tumorous and non-tumorous tissues from HCV-positive patients with hepatocellular carcinoma
    • Formeister EJ, Tsuchiya M, Fujii H, Shpyleva S, Pogribny IP, Rusyn I (2010). Comparative analysis of promoter methylation and gene expression endpoints between tumorous and non-tumorous tissues from HCV-positive patients with hepatocellular carcinoma. Mutat Res 692:26-33.
    • (2010) Mutat Res , vol.692 , pp. 26-33
    • Formeister, E.J.1    Tsuchiya, M.2    Fujii, H.3    Shpyleva, S.4    Pogribny, I.P.5    Rusyn, I.6
  • 15
    • 84897037529 scopus 로고    scopus 로고
    • Stat3 and gap junctions in normal and lung cancer cells
    • Guy S, Geletu M, Arulanandam R, Raptis L (2014). Stat3 and gap junctions in normal and lung cancer cells. Cancers (Basel) 6:646-662.
    • (2014) Cancers (Basel) , vol.6 , pp. 646-662
    • Guy, S.1    Geletu, M.2    Arulanandam, R.3    Raptis, L.4
  • 16
    • 43049141867 scopus 로고    scopus 로고
    • Quantitative promoter methylation analysis of hepatocellular carcinoma, cirrhotic and normal liver
    • Harder J, Opitz OG, Brabender J, Olschewski M, Blum HE, Nomoto S, Usadel H (2008). Quantitative promoter methylation analysis of hepatocellular carcinoma, cirrhotic and normal liver. Int J Cancer 122:2800-2804.
    • (2008) Int J Cancer , vol.122 , pp. 2800-2804
    • Harder, J.1    Opitz, O.G.2    Brabender, J.3    Olschewski, M.4    Blum, H.E.5    Nomoto, S.6    Usadel, H.7
  • 17
    • 24944542337 scopus 로고    scopus 로고
    • Major causes of death among men and women in China
    • He J, Gu D, Wu X, Reynolds K, Duan X, Yao C, et al. (2005). Major causes of death among men and women in China. N Engl J Med 353:1124-1134.
    • (2005) N Engl J Med , vol.353 , pp. 1124-1134
    • He, J.1    Gu, D.2    Wu, X.3    Reynolds, K.4    Duan, X.5    Yao, C.6
  • 18
    • 0030887086 scopus 로고    scopus 로고
    • Hypermethylation of the APC (adenomatous polyposis coli) gene promoter region in human colorectal carcinoma
    • Hiltunen MO, Alhonen L, Koistinaho J, Myöhänen S, Pääkkönen M, Marin S, et al. (1997). Hypermethylation of the APC (adenomatous polyposis coli) gene promoter region in human colorectal carcinoma. Int J Cancer 70:644-648.
    • (1997) Int J Cancer , vol.70 , pp. 644-648
    • Hiltunen, M.O.1    Alhonen, L.2    Koistinaho, J.3    Myöhänen, S.4    Pääkkönen, M.5    Marin, S.6
  • 19
    • 79957507207 scopus 로고    scopus 로고
    • Quantitative methylation analysis of multiple genes using methylation-sensitive restriction enzyme-based quantitative PCR for the detection of hepatocellular carcinoma
    • Hua D, Hu Y, Wu YY, Cheng ZH, Yu J, Du X, Huang ZH (2011). Quantitative methylation analysis of multiple genes using methylation-sensitive restriction enzyme-based quantitative PCR for the detection of hepatocellular carcinoma. Exp Mol Pathol 91:455-460.
    • (2011) Exp Mol Pathol , vol.91 , pp. 455-460
    • Hua, D.1    Hu, Y.2    Wu, Y.Y.3    Zh, C.4    Yu, J.5    Du, X.6    Zh, H.7
  • 20
    • 80053515231 scopus 로고    scopus 로고
    • Quantitative analysis of multiple methylated genes in plasma for the diagnosis and prognosis of hepatocellular carcinoma
    • Huang ZH, Hu Y, Hua D, Wu YY, Song MX, Cheng ZH (2011). Quantitative analysis of multiple methylated genes in plasma for the diagnosis and prognosis of hepatocellular carcinoma. Exp Mol Pathol 91:702-707.
    • (2011) Exp Mol Pathol , vol.91 , pp. 702-707
    • Zh, H.1    Hu, Y.2    Hua, D.3    Wu, Y.Y.4    Song, M.X.5    Zh, C.6
  • 21
    • 84859942963 scopus 로고    scopus 로고
    • Impact of the location of CpG methylation within the GSTP1 gene on its specificity as a DNA marker for hepatocellular carcinoma
    • Jain S, Chen S, Chang KC, Lin YJ, Hu CT, Boldbaatar B, et al. (2012). Impact of the location of CpG methylation within the GSTP1 gene on its specificity as a DNA marker for hepatocellular carcinoma. PLoS One 7:e35789.
    • (2012) PLoS One , vol.7 , pp. e35789
    • Jain, S.1    Chen, S.2    Chang, K.C.3    Lin, Y.J.4    Hu, C.T.5    Boldbaatar, B.6
  • 22
  • 23
    • 0141648473 scopus 로고    scopus 로고
    • Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis
    • Lee S, Lee HJ, Kim JH, Lee HS, Jang JJ, Kang GH (2003). Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis. Am J Pathol 163:1371-1378.
    • (2003) Am J Pathol , vol.163 , pp. 1371-1378
    • Lee, S.1    Lee, H.J.2    Kim, J.H.3    Lee, H.S.4    Jang, J.J.5    Kang, G.H.6
  • 24
    • 34447321310 scopus 로고    scopus 로고
    • Epigenetic defects of hepatocellular carcinoma are already found in non-neoplastic liver cells from patients with hereditary haemochromatosis
    • Lehmann U, Wingen LU, Brakensiek K, Wedemeyer H, Becker T, Heim A, et al. (2007). Epigenetic defects of hepatocellular carcinoma are already found in non-neoplastic liver cells from patients with hereditary haemochromatosis. Hum Mol Genet 16:1335-1342.
    • (2007) Hum Mol Genet , vol.16 , pp. 1335-1342
    • Lehmann, U.1    Wingen, L.U.2    Brakensiek, K.3    Wedemeyer, H.4    Becker, T.5    Heim, A.6
  • 25
    • 84862499187 scopus 로고    scopus 로고
    • Promoter hypermethylation of DNA damage response genes in hepatocellular carcinoma
    • Li Z, Zhang H, Yang J, Hao T, Li S (2012). Promoter hypermethylation of DNA damage response genes in hepatocellular carcinoma. Cell Biol Int 36:427-432.
    • (2012) Cell Biol Int , vol.36 , pp. 427-432
    • Li, Z.1    Zhang, H.2    Yang, J.3    Hao, T.4    Li, S.5
  • 26
    • 33845994601 scopus 로고    scopus 로고
    • Correlations of CpG island methylator phenotype and OPCML gene methylation to carcinogenesis of hepatocellular carcinoma
    • Liu WJ, Wang L, Wang JP, Li JQ, Zhang CQ, Deng L, Yuan YF (2006). Correlations of CpG island methylator phenotype and OPCML gene methylation to carcinogenesis of hepatocellular carcinoma. Chinese J Cancer 25:696-700.
    • (2006) Chinese J Cancer , vol.25 , pp. 696-700
    • Liu, W.J.1    Wang, L.2    Wang, J.P.3    Li, J.Q.4    Zhang, C.Q.5    Deng, L.6    Yuan, Y.F.7
  • 27
    • 67649870740 scopus 로고    scopus 로고
    • Aberrant DNA methylation profile of hepatocellular carcinoma and surgically resected margin
    • Lou C, Du Z, Yang B, Gao Y, Wang Y, Fang S (2009). Aberrant DNA methylation profile of hepatocellular carcinoma and surgically resected margin. Cancer Sci 100:996-1004.
    • (2009) Cancer Sci , vol.100 , pp. 996-1004
    • Lou, C.1    Du, Z.2    Yang, B.3    Gao, Y.4    Wang, Y.5    Fang, S.6
  • 28
    • 12444285909 scopus 로고    scopus 로고
    • Alcohol, tobacco and obesity are synergistic risk factors for hepatocellular carcinoma
    • Marrero JA, Fontana RJ, Fu S, Conjeevaram HS, Su GL, Lok AS (2005). Alcohol, tobacco and obesity are synergistic risk factors for hepatocellular carcinoma. J Hepatol 42:218-224.
    • (2005) J Hepatol , vol.42 , pp. 218-224
    • Marrero, J.A.1    Fontana, R.J.2    Fu, S.3    Conjeevaram, H.S.4    Su, G.L.5    Lok, A.S.6
  • 29
    • 77954643355 scopus 로고    scopus 로고
    • Chronic hepatitis B and hepatocellular carcinoma
    • McClune AC, Tong MJ (2010). Chronic hepatitis B and hepatocellular carcinoma. Clin Liver Dis 14:461-476.
    • (2010) Clin Liver Dis , vol.14 , pp. 461-476
    • McClune, A.C.1    Tong, M.J.2
  • 30
    • 3242881890 scopus 로고    scopus 로고
    • Methylation status of suppressor of cytokine signaling-1 gene in hepatocellular carcinoma
    • Miyoshi H, Fujie H, Moriya K, Shintani Y, Tsutsumi T, Makuuchi M, et al. (2004). Methylation status of suppressor of cytokine signaling-1 gene in hepatocellular carcinoma. J Gastroenterol 39:563-569.
    • (2004) J Gastroenterol , vol.39 , pp. 563-569
    • Miyoshi, H.1    Fujie, H.2    Moriya, K.3    Shintani, Y.4    Tsutsumi, T.5    Makuuchi, M.6
  • 31
    • 67449090372 scopus 로고    scopus 로고
    • Methylation of multiple genes as molecular markers for diagnosis of a small, well-differentiated hepatocellular carcinoma
    • Moribe T, Iizuka N, Miura T, Kimura N, Tamatsukuri S, Ishitsuka H, et al. (2009). Methylation of multiple genes as molecular markers for diagnosis of a small, well-differentiated hepatocellular carcinoma. Int J Cancer 125:388-397.
    • (2009) Int J Cancer , vol.125 , pp. 388-397
    • Moribe, T.1    Iizuka, N.2    Miura, T.3    Kimura, N.4    Tamatsukuri, S.5    Ishitsuka, H.6
  • 32
    • 35648947815 scopus 로고    scopus 로고
    • Hypermethylation of multiple genes as clonal markers in multicentric hepatocellular carcinoma
    • Nomoto S, Kinoshita T, Kato K, Otani S, Kasuya H, Takeda S, et al. (2007). Hypermethylation of multiple genes as clonal markers in multicentric hepatocellular carcinoma. Br J Cancer 97:1260-1265.
    • (2007) Br J Cancer , vol.97 , pp. 1260-1265
    • Nomoto, S.1    Kinoshita, T.2    Kato, K.3    Otani, S.4    Kasuya, H.5    Takeda, S.6
  • 33
    • 0242610382 scopus 로고    scopus 로고
    • Methylation-mediated silencing of SOCS-1 gene in hepatocellular carcinoma derived from cirrhosis
    • Okochi O, Hibi K, Sakai M, Inoue S, Takeda S, Kaneko T, Nakao A (2003). Methylation-mediated silencing of SOCS-1 gene in hepatocellular carcinoma derived from cirrhosis. Clin Cancer Res 9:5295-5298.
    • (2003) Clin Cancer Res , vol.9 , pp. 5295-5298
    • Okochi, O.1    Hibi, K.2    Sakai, M.3    Inoue, S.4    Takeda, S.5    Kaneko, T.6    Nakao, A.7
  • 34
    • 84943152635 scopus 로고    scopus 로고
    • Detection of methylation of P16 and APC gene in liver cancer tissue and plasma and its clinical significance
    • Qi YP, Cui LH, Song Y (2013). Detection of methylation of P16 and APC gene in liver cancer tissue and plasma and its clinical significance. Med J Qilu 28:189-195.
    • (2013) Med J Qilu , vol.28 , pp. 189-195
    • Qi, Y.P.1    Cui, L.H.2    Song, Y.3
  • 35
    • 84901052574 scopus 로고    scopus 로고
    • Epigenetic mechanism involved in the HBV/HCV-related hepatocellular carcinoma tumorigenesis
    • Rongrui L, Na H, Zongfang L, Fanpu J, Shiwen J (2014). Epigenetic mechanism involved in the HBV/HCV-related hepatocellular carcinoma tumorigenesis. Curr Pharm Des 20:1715-1725.
    • (2014) Curr Pharm des , vol.20 , pp. 1715-1725
    • Rongrui, L.1    Na, H.2    Zongfang, L.3    Fanpu, J.4    Shiwen, J.5
  • 37
    • 84867263824 scopus 로고    scopus 로고
    • GSTP1 methylation and polymorphism increase the risk of breast cancer and the effects of diet and lifestyle in breast cancer patients
    • Saxena A, Dhillon VS, Shahid M, Khalil HS, Rani M, Prasad Das T, et al. (2012). GSTP1 methylation and polymorphism increase the risk of breast cancer and the effects of diet and lifestyle in breast cancer patients. Exp Ther Med 4:1097-1103.
    • (2012) Exp Ther Med , vol.4 , pp. 1097-1103
    • Saxena, A.1    Dhillon, V.S.2    Shahid, M.3    Khalil, H.S.4    Rani, M.5    Prasad Das, T.6
  • 38
    • 34548090762 scopus 로고    scopus 로고
    • Differential DNA methylation associated with hepatitis B virus infection in hepatocellular carcinoma
    • Su PF, Lee TC, Lin PJ, Lee PH, Jeng YM, Chen CH, et al. (2007). Differential DNA methylation associated with hepatitis B virus infection in hepatocellular carcinoma. Int J Cancer 121:1257-1264.
    • (2007) Int J Cancer , vol.121 , pp. 1257-1264
    • Su, P.F.1    Lee, T.C.2    Lin, P.J.3    Lee, P.H.4    Jeng, Y.M.5    Chen, C.H.6
  • 39
    • 25844440793 scopus 로고    scopus 로고
    • Detection of aberrant promoter CpG islands hypermethylation of GSTP1 in human primary hepatocellular carcinomas
    • Wang JH, Bo Li, Sun ZL, Sun ZF, Guan QL (2005). Detection of aberrant promoter CpG islands hypermethylation of GSTP1 in human primary hepatocellular carcinomas. J Sichuan UniV (Med Sci Edi) 36:686-688.
    • (2005) J Sichuan UniV (Med Sci Edi) , vol.36 , pp. 686-688
    • Wang, J.H.1    Li, B.2    Sun, Z.L.3    Sun, Z.F.4    Guan, Q.L.5
  • 40
    • 84875310269 scopus 로고    scopus 로고
    • UCN-01 induces S and G2/M cell cycle arrest through the p53/p21(waf1) or CHK2/CDC25C pathways and can suppress invasion in human hepatoma cell lines
    • Wu G, Lin N, Xu L, Liu B, Feitelson MA (2013). UCN-01 induces S and G2/M cell cycle arrest through the p53/p21(waf1) or CHK2/CDC25C pathways and can suppress invasion in human hepatoma cell lines. BMC Cancer 13:167.
    • (2013) BMC Cancer , vol.13 , pp. 167
    • Wu, G.1    Lin, N.2    Xu, L.3    Liu, B.4    Feitelson, M.A.5
  • 41
    • 84871493022 scopus 로고    scopus 로고
    • The role of aflatoxins in hepatocellular carcinoma
    • Wu HC, Santella R (2012). The role of aflatoxins in hepatocellular carcinoma. Hepat Mon 12 (HCC):e7238.
    • (2012) Hepat Mon , vol.12 , Issue.HCC , pp. e7238
    • Wu, H.C.1    Santella, R.2
  • 42
    • 84905161870 scopus 로고    scopus 로고
    • Promoter methylation and mRNA expression of gene in APC hepatocellular carcinoma
    • Wu L, Zhu LX, Geng XP, Xiong QR (2007). Promoter methylation and mRNA expression of gene in APC hepatocellular carcinoma. J Hepatobiliary Surg 15:378-381.
    • (2007) J Hepatobiliary Surg , vol.15 , pp. 378-381
    • Wu, L.1    Zhu, L.X.2    Geng, X.P.3    Xiong, Q.R.4
  • 43
    • 0041924707 scopus 로고    scopus 로고
    • Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma
    • Yang B, Guo M, Herman JG, Clark DP (2003). Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma. Am J Pathol 163:1101-1107.
    • (2003) Am J Pathol , vol.163 , pp. 1101-1107
    • Yang, B.1    Guo, M.2    Herman, J.G.3    Clark, D.P.4
  • 44
    • 84930486268 scopus 로고    scopus 로고
    • DNA methylation of GSTP1 in human prostate tissues: Pyrosequencing analysis
    • Yoon HY, Kim YW, Kang HW, Kim WT, Yun SJ, Lee SC, et al. (2012). DNA methylation of GSTP1 in human prostate tissues: pyrosequencing analysis. Korean J Urol 53:200-205.
    • (2012) Korean J Urol , vol.53 , pp. 200-205
    • Yoon, H.Y.1    Kim, Y.W.2    Kang, H.W.3    Kim, W.T.4    Yun, S.J.5    Lee, S.C.6
  • 45
    • 0035042611 scopus 로고    scopus 로고
    • SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growthsuppression activity
    • Yoshikawa H, Matsubara K, Qian GS, Jackson P, Groopman JD, Manning JE, et al. (2001). SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growthsuppression activity. Nat Genet 28:29-35.
    • (2001) Nat Genet , vol.28 , pp. 29-35
    • Yoshikawa, H.1    Matsubara, K.2    Qian, G.S.3    Jackson, P.4    Groopman, J.D.5    Manning, J.E.6
  • 46
    • 1542322897 scopus 로고    scopus 로고
    • Methylation profiling of twenty-four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis
    • Yu J, Zhang HY, Ma ZZ, Lu W, Wang YF, Zhu JD (2003). Methylation profiling of twenty-four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis. Cell Res 13:319-333.
    • (2003) Cell Res , vol.13 , pp. 319-333
    • Yu, J.1    Zhang, H.Y.2    Ma, Z.Z.3    Lu, W.4    Wang, Y.F.5    Zhu, J.D.6
  • 47
    • 3042707323 scopus 로고    scopus 로고
    • Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis
    • Yu J, Ni M, Xu J, Zhang H, Gao B, Gu J, et al. (2002). Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis. BMC Cancer 2:29.
    • (2002) BMC Cancer , vol.2 , pp. 29
    • Yu, J.1    Ni, M.2    Xu, J.3    Zhang, H.4    Gao, B.5    Gu, J.6
  • 48
    • 84943161437 scopus 로고    scopus 로고
    • Promoter methylation status and protein expression of APC gene in hepatocellular carcinoma
    • Yuan WP, Shang H, Chun Y, JR Liu, Zhao YN (2010). Promoter methylation status and protein expression of APC gene in hepatocellular carcinoma. Mod Oncol 18:1795-1797.
    • (2010) Mod Oncol , vol.18 , pp. 1795-1797
    • Yuan, W.P.1    Shang, H.2    Chun, Y.3    Liu, J.R.4    Zhao, Y.N.5
  • 49
    • 84895799078 scopus 로고    scopus 로고
    • An integrated analysis of SOCS1 down-regulation in HBV infection-related hepatocellular carcinoma
    • Zhang X, Wang J, Cheng J, Ding S, Li M, Sun S, et al. (2013). An integrated analysis of SOCS1 down-regulation in HBV infection-related hepatocellular carcinoma. J Viral Hepat 21:264-271.
    • (2013) J Viral Hepat , vol.21 , pp. 264-271
    • Zhang, X.1    Wang, J.2    Cheng, J.3    Ding, S.4    Li, M.5    Sun, S.6
  • 50
    • 84934925749 scopus 로고    scopus 로고
    • Methylation of glutathione S-transferases P1 in hepatocellular carcinoma
    • Zhang YC, Chen JX, Deng CS (2008). Methylation of glutathione S-transferases P1 in hepatocellular carcinoma. Chin J Gastrienterol Hepatol 15:399-406.
    • (2008) Chin J Gastrienterol Hepatol , vol.15 , pp. 399-406
    • Zhang, Y.C.1    Chen, J.X.2    Deng, C.S.3
  • 51
    • 0036554834 scopus 로고    scopus 로고
    • Silencing of GSTP1 gene by CpG island DNA hypermethylation in HBV-associated hepatocellular carcinomas
    • Zhong S, Tang MW, Yeo W, Liu C, Lo YM, Johnson PJ (2002). Silencing of GSTP1 gene by CpG island DNA hypermethylation in HBV-associated hepatocellular carcinomas. Clin Cancer Res 8:1087-1092.
    • (2002) Clin Cancer Res , vol.8 , pp. 1087-1092
    • Zhong, S.1    Tang, M.W.2    Yeo, W.3    Liu, C.4    Lo, Y.M.5    Johnson, P.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.