Interdependent and independent roles of type I interferons and IL-6 in innate immune, neuroinflammatory and sickness behaviour responses to systemic poly I: C

Brain, Behavior, and Immunity

Volumn 48, Issue , 2015, Pages 274-286

  Murray, Carol ^a   Griffin, Éadaoin W ^a   O'Loughlin, Elaine ^a   Lyons, Aoife ^a   Sherwin, Eoin ^a   Ahmed, Suaad ^a   Stevenson, Nigel J ^a   Harkin, Andrew ^a   Cunningham, Colm ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Behaviour; Burrowing; Cytokine; Depression; Hippocampus; Hypoactivity; IDO; IFN a; IFN b; IL 6; Interferon; Kynurenine; Neuroinflammation; Sickness; STAT1; Viral

Indexed keywords

BETA INTERFERON; INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 6; KYNURENINE; POLYINOSINIC POLYCYTIDYLIC ACID; STAT1 PROTEIN; TRYPTOPHAN; TUMOR NECROSIS FACTOR ALPHA; INTERFERON RECEPTOR; TUMOR NECROSIS FACTOR;

AMINO ACID METABOLISM; ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOREXIA; ARTICLE; BEHAVIOR CHANGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; FEMALE; GENE EXPRESSION; HIPPOCAMPUS; HYPOACTIVITY; HYPOTHALAMUS; HYPOTHERMIA; ILLNESS BEHAVIOR; INNATE IMMUNITY; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PLASMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; TRYPTOPHAN KYNURENINE METABOLISM PATHWAY; WEIGHT REDUCTION; WILD TYPE; ANIMAL; BRAIN; DRUG EFFECTS; GENETICS; INFLAMMATION; KNOCKOUT MOUSE; METABOLISM; MOTOR ACTIVITY; PHYSIOLOGY;

ANIMALS; BRAIN; ILLNESS BEHAVIOR; IMMUNITY, INNATE; INFLAMMATION; INTERFERON TYPE I; INTERLEUKIN-1BETA; INTERLEUKIN-6; KYNURENINE; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; POLY I-C; RECEPTORS, INTERFERON; TRYPTOPHAN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84942988008     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2015.04.009     Document Type: Article

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