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Volumn 21, Issue 16, 2015, Pages 3716-3726

A hypoxia-induced vascular endothelial-to-mesenchymal transition in development of radiation-induced pulmonary fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

2 METHOXYESTRADIOL; HYPOXIA INDUCIBLE FACTOR 1ALPHA; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; 2-METHOXYESTRADIOL; COLLAGEN; ESTRADIOL; HIF1A PROTEIN, HUMAN;

EID: 84942892712     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-14-3193     Document Type: Article
Times cited : (132)

References (39)
  • 3
    • 31844456882 scopus 로고    scopus 로고
    • Amifostine reduces side effects and improves complete response rate during radiotherapy: Results of a metaanalysis
    • Sasse AD, Clark LG, Sasse EC, Clark OA. Amifostine reduces side effects and improves complete response rate during radiotherapy: results of a metaanalysis. Int J Radiat Oncol Biol Phys 2006;64:784-91.
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , pp. 784-791
    • Sasse, A.D.1    Clark, L.G.2    Sasse, E.C.3    Clark, O.A.4
  • 4
    • 26944449737 scopus 로고    scopus 로고
    • Radiation pneumonitis and pulmonary fibrosis in non-small cell lung cancer: Pulmonary function, prediction, and prevention
    • Mehta V. Radiation pneumonitis and pulmonary fibrosis in non-small cell lung cancer: pulmonary function, prediction, and prevention. Int J Radiat Oncol Biol Phys 2005;63:5-24.
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 5-24
    • Mehta, V.1
  • 5
    • 77957884094 scopus 로고    scopus 로고
    • Pathogenetic mechanisms in radiation fibrosis
    • Yarnold J, Brotons MC. Pathogenetic mechanisms in radiation fibrosis. Radiother Oncol 2010;97:149-61.
    • (2010) Radiother Oncol , vol.97 , pp. 149-161
    • Yarnold, J.1    Brotons, M.C.2
  • 6
    • 0029058925 scopus 로고
    • Cellular basis of radiation-induced fibrosis
    • Rodemann HP, Bamberg M. Cellular basis of radiation-induced fibrosis. Radiother Oncol 1995;35:83-90.
    • (1995) Radiother Oncol , vol.35 , pp. 83-90
    • Rodemann, H.P.1    Bamberg, M.2
  • 8
    • 84878613101 scopus 로고    scopus 로고
    • EMT and EndMT: Regulated in similar ways?
    • Saito A. EMT and EndMT: regulated in similar ways? J Biochem 2013;153:493-5.
    • (2013) J Biochem , vol.153 , pp. 493-495
    • Saito, A.1
  • 9
    • 84872875594 scopus 로고    scopus 로고
    • Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition
    • Balli D, Ustiyan V, Zhang Y, Wang IC, Masino AJ, Ren X, et al. Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition. EMBO J 2013;32:231-44.
    • (2013) EMBO J , vol.32 , pp. 231-244
    • Balli, D.1    Ustiyan, V.2    Zhang, Y.3    Wang, I.C.4    Masino, A.J.5    Ren, X.6
  • 11
    • 55249126800 scopus 로고    scopus 로고
    • The role of endothelial-to-mesenchymal transition in cancer progression
    • Potenta S, Zeisberg E, Kalluri R. The role of endothelial-to-mesenchymal transition in cancer progression. Br J Cancer 2008;99:1375-9.
    • (2008) Br J Cancer , vol.99 , pp. 1375-1379
    • Potenta, S.1    Zeisberg, E.2    Kalluri, R.3
  • 12
    • 84857824476 scopus 로고    scopus 로고
    • Regulation of endothelial cell plasticity by TGF-beta
    • van Meeteren LA, ten Dijke P. Regulation of endothelial cell plasticity by TGF-beta. Cell Tissue Res 2012;347:177-86.
    • (2012) Cell Tissue Res , vol.347 , pp. 177-186
    • Van Meeteren, L.A.1    Ten Dijke, P.2
  • 14
    • 77949283873 scopus 로고    scopus 로고
    • Understanding radiation-induced vascular disease
    • Weintraub NL, Jones WK, Manka D. Understanding radiation-induced vascular disease. J Am Coll Cardiol 2010;55:1237-9.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 1237-1239
    • Weintraub, N.L.1    Jones, W.K.2    Manka, D.3
  • 15
    • 84877307533 scopus 로고    scopus 로고
    • The effect of oxidized low-density lipoprotein (ox-LDL) on radiation-induced endothelial-tomesenchymal transition
    • Kim M, Choi SH, Jin YB, Lee HJ, Ji YH, Kim J, et al. The effect of oxidized low-density lipoprotein (ox-LDL) on radiation-induced endothelial-tomesenchymal transition. Int J Radiat Biol 2013;89:356-63.
    • (2013) Int J Radiat Biol , vol.89 , pp. 356-363
    • Kim, M.1    Choi, S.H.2    Jin, Y.B.3    Lee, H.J.4    Ji, Y.H.5    Kim, J.6
  • 16
    • 84904089073 scopus 로고    scopus 로고
    • A preclinical rodent model of acute radiation-induced lung injury after ablative focal irradiation reflecting clinical stereotactic body radiotherapy
    • Hong ZY, Lee HJ, Choi WH, Lee YJ, Eun SH, Lee JI, et al. A preclinical rodent model of acute radiation-induced lung injury after ablative focal irradiation reflecting clinical stereotactic body radiotherapy. Radiat Res 2014;182:83-91.
    • (2014) Radiat Res , vol.182 , pp. 83-91
    • Hong, Z.Y.1    Lee, H.J.2    Choi, W.H.3    Lee, Y.J.4    Eun, S.H.5    Lee, J.I.6
  • 17
    • 76249092135 scopus 로고    scopus 로고
    • Variable inhibition of thrombospondin 1 against liver and lung metastases through differential activation ofmetalloproteinase ADAMTS1
    • Lee YJ, Koch M, Karl D, Torres-Collado AX, Fernando NT, Rothrock C, et al. Variable inhibition of thrombospondin 1 against liver and lung metastases through differential activation ofmetalloproteinase ADAMTS1. Cancer Res 2010;70:948-56.
    • (2010) Cancer Res , vol.70 , pp. 948-956
    • Lee, Y.J.1    Koch, M.2    Karl, D.3    Torres-Collado, A.X.4    Fernando, N.T.5    Rothrock, C.6
  • 18
    • 84865146919 scopus 로고    scopus 로고
    • Soluble HSPB1 regulates VEGF-mediated angiogenesis through their direct interaction
    • Lee YJ, Lee HJ, Choi SH, Jin YB, An HJ, Kang JH, et al. Soluble HSPB1 regulates VEGF-mediated angiogenesis through their direct interaction. Angiogenesis 2012;15:229-42.
    • (2012) Angiogenesis , vol.15 , pp. 229-242
    • Lee, Y.J.1    Lee, H.J.2    Choi, S.H.3    Jin, Y.B.4    An, H.J.5    Kang, J.H.6
  • 19
    • 33748375828 scopus 로고    scopus 로고
    • Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
    • Kim KK, Kugler MC, Wolters PJ, Robillard L, Galvez MG, Brumwell AN, et al. Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci U S A 2006;103:13180-5.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 13180-13185
    • Kim, K.K.1    Kugler, M.C.2    Wolters, P.J.3    Robillard, L.4    Galvez, M.G.5    Brumwell, A.N.6
  • 20
    • 33748293905 scopus 로고    scopus 로고
    • Lung fibrosis induced by bleomycin: Structural changes and overview of recent advances
    • Grade NR, Peao MND, Sa CMd, P. Aguas A. Lung fibrosis induced by bleomycin: structural changes and overview of recent advances. Scanning Microsc 1998;12:487-94.
    • (1998) Scanning Microsc , vol.12 , pp. 487-494
    • Grade, N.R.1    Peao, M.N.D.2    Sa, C.M.D.3    Aguas, P.A.4
  • 21
    • 70450142560 scopus 로고    scopus 로고
    • Inflammation and EMT: An alliance towards organ fibrosis and cancer progression
    • Lopez-Novoa JM, Nieto MA. Inflammation and EMT: an alliance towards organ fibrosis and cancer progression. EMBO Mol Med 2009;1:303-14.
    • (2009) EMBO Mol Med , vol.1 , pp. 303-314
    • Lopez-Novoa, J.M.1    Nieto, M.A.2
  • 23
    • 84879690589 scopus 로고    scopus 로고
    • EndMT contributes to the onset and progression of cerebral cavernous malformations
    • Maddaluno L, Rudini N, Cuttano R, Bravi L, Giampietro C, Corada M, et al. EndMT contributes to the onset and progression of cerebral cavernous malformations. Nature 2013;498:492-6.
    • (2013) Nature , vol.498 , pp. 492-496
    • Maddaluno, L.1    Rudini, N.2    Cuttano, R.3    Bravi, L.4    Giampietro, C.5    Corada, M.6
  • 24
    • 33751298106 scopus 로고    scopus 로고
    • 2-methoxyestradiol, an endogenous mammalian metabolite, radiosensitizes colon carcinoma cells through c-Jun. NH2-terminal kinase activation
    • Zou H, Adachi M, Imai K, Hareyama M, Yoshioka K, Zhao S, et al. 2-methoxyestradiol, an endogenous mammalian metabolite, radiosensitizes colon carcinoma cells through c-Jun. NH2-terminal kinase activation. Clin Cancer Res 2006;12:6532-9.
    • (2006) Clin Cancer Res , vol.12 , pp. 6532-6539
    • Zou, H.1    Adachi, M.2    Imai, K.3    Hareyama, M.4    Yoshioka, K.5    Zhao, S.6
  • 25
    • 77954311612 scopus 로고    scopus 로고
    • 2-Methoxyestradiol-biology and mechanism of action
    • Mueck AO, Seeger H. 2-Methoxyestradiol-biology and mechanism of action. Steroids 2010;75:625-31.
    • (2010) Steroids , vol.75 , pp. 625-631
    • Mueck, A.O.1    Seeger, H.2
  • 26
    • 13844267558 scopus 로고    scopus 로고
    • The pathology of ionizing radiation as defined by morphologic patterns
    • Fajardo LF. The pathology of ionizing radiation as defined by morphologic patterns. Acta Oncol 2005;44:13-22.
    • (2005) Acta Oncol , vol.44 , pp. 13-22
    • Fajardo, L.F.1
  • 27
    • 0347989194 scopus 로고    scopus 로고
    • Up-regulation and activation of proteinase-activated receptor 2 in early and delayed radiation injury in the rat intestine: Influence of biological activators of proteinase-activated receptor 2
    • Wang J, Zheng H, Hollenberg MD, Wijesuriya SJ, Ou X, Hauer-Jensen M. Up-regulation and activation of proteinase-activated receptor 2 in early and delayed radiation injury in the rat intestine: influence of biological activators of proteinase-activated receptor 2. Radiat Res 2003;160:524-35.
    • (2003) Radiat Res , vol.160 , pp. 524-535
    • Wang, J.1    Zheng, H.2    Hollenberg, M.D.3    Wijesuriya, S.J.4    Ou, X.5    Hauer-Jensen, M.6
  • 28
    • 0034054128 scopus 로고    scopus 로고
    • Control of radiation-induced pneumopathy and lung fibrosis by angiotensinconverting enzyme inhibitors and an angiotensin II type 1 receptor blocker
    • Molteni A, Moulder JE, Cohen EF, Ward WF, Fish BL, Taylor JM, et al. Control of radiation-induced pneumopathy and lung fibrosis by angiotensinconverting enzyme inhibitors and an angiotensin II type 1 receptor blocker. Int J Radiat Biol 2000;76:523-32.
    • (2000) Int J Radiat Biol , vol.76 , pp. 523-532
    • Molteni, A.1    Moulder, J.E.2    Cohen, E.F.3    Ward, W.F.4    Fish, B.L.5    Taylor, J.M.6
  • 29
    • 16044364385 scopus 로고    scopus 로고
    • Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis
    • Santana P, Pena LA, Haimovitz-Friedman A, Martin S, Green D, McLoughlin M, et al. Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. Cell 1996;86:189-99.
    • (1996) Cell , vol.86 , pp. 189-199
    • Santana, P.1    Pena, L.A.2    Haimovitz-Friedman, A.3    Martin, S.4    Green, D.5    McLoughlin, M.6
  • 31
    • 79954463134 scopus 로고    scopus 로고
    • Interdependence of HIF-1alpha and TGF-beta/Smad3 signaling in normoxic and hypoxic renal epithelial cell collagen expression
    • Basu RK, Hubchak S, Hayashida T, Runyan CE, Schumacker PT, Schnaper HW. Interdependence of HIF-1alpha and TGF-beta/Smad3 signaling in normoxic and hypoxic renal epithelial cell collagen expression. Am J Physiol Renal Physiol 2011;300:F898-905.
    • (2011) Am J Physiol Renal Physiol , vol.300 , pp. F898-F905
    • Basu, R.K.1    Hubchak, S.2    Hayashida, T.3    Runyan, C.E.4    Schumacker, P.T.5    Schnaper, H.W.6
  • 32
    • 34548330009 scopus 로고    scopus 로고
    • The NOX on pulmonary hypertension
    • Sanders KA, Hoidal JR. The NOX on pulmonary hypertension. Circ Res 2007;101:224-6.
    • (2007) Circ Res , vol.101 , pp. 224-226
    • Sanders, K.A.1    Hoidal, J.R.2
  • 33
    • 79955784909 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha mediates TGF-beta-induced PAI-1 production in alveolar macrophages in pulmonary fibrosis
    • Ueno M, Maeno T, Nomura M, Aoyagi-Ikeda K, Matsui H, Hara K, et al. Hypoxia-inducible factor-1alpha mediates TGF-beta-induced PAI-1 production in alveolar macrophages in pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol 2011;300:L740-52.
    • (2011) Am J Physiol Lung Cell Mol Physiol , vol.300 , pp. L740-L752
    • Ueno, M.1    Maeno, T.2    Nomura, M.3    Aoyagi-Ikeda, K.4    Matsui, H.5    Hara, K.6
  • 36
    • 34548548398 scopus 로고    scopus 로고
    • Radiosensitization and modulation of p44/42 mitogen-activated protein kinase by 2-Methoxyestradiol in prostate cancer models
    • Casarez EV, Dunlap-Brown ME, Conaway MR, Amorino GP. Radiosensitization and modulation of p44/42 mitogen-activated protein kinase by 2-Methoxyestradiol in prostate cancer models. Cancer Res 2007;67:8316-24.
    • (2007) Cancer Res , vol.67 , pp. 8316-8324
    • Casarez, E.V.1    Dunlap-Brown, M.E.2    Conaway, M.R.3    Amorino, G.P.4
  • 37
    • 36448951976 scopus 로고    scopus 로고
    • Enhanced radiationinduced cytotoxic effect by 2-ME in glioma cells is mediated by induction of cell cycle arrest and DNAdamage via activation of ATM pathways
    • Zou H, Zhao S, Zhang J, Lv G, Zhang X, Yu H, et al. Enhanced radiationinduced cytotoxic effect by 2-ME in glioma cells is mediated by induction of cell cycle arrest and DNAdamage via activation of ATM pathways. Brain Res 2007;1185:231-8.
    • (2007) Brain Res , vol.1185 , pp. 231-238
    • Zou, H.1    Zhao, S.2    Zhang, J.3    Lv, G.4    Zhang, X.5    Yu, H.6
  • 38
    • 69949148071 scopus 로고    scopus 로고
    • 2-Methoxyestradiolinduced radiosensitization is independent of SOD but depends on inhibition of Akt and DNA-PKcs activities
    • Florczak U, Toulany M, Kehlbach R, Peter Rodemann H. 2-Methoxyestradiolinduced radiosensitization is independent of SOD but depends on inhibition of Akt and DNA-PKcs activities. Radiother Oncol 2009;92:334-8.
    • (2009) Radiother Oncol , vol.92 , pp. 334-338
    • Florczak, U.1    Toulany, M.2    Kehlbach, R.3    Peter Rodemann, H.4
  • 39
    • 79954421458 scopus 로고    scopus 로고
    • 2-Methoxyestradiol, an endogenous estrogen metabolite, sensitizes radioresistant MCF-7/FIR breast cancer cells through multiple mechanisms
    • Salama S, Diaz-Arrastia C, Patel D, Botting S, Hatch S. 2-Methoxyestradiol, an endogenous estrogen metabolite, sensitizes radioresistant MCF-7/FIR breast cancer cells through multiple mechanisms. Int J Radiat Oncol Biol Phys 2011;80:231-9.
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , pp. 231-239
    • Salama, S.1    Diaz-Arrastia, C.2    Patel, D.3    Botting, S.4    Hatch, S.5


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