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Volumn 22, Issue 7, 2015, Pages 918-930

Nose to brain microemulsion-based drug delivery system of rivastigmine: Formulation and ex-vivo characterization

Author keywords

Alzheimer's disease; brain targeting; intranasal route; mucoadhesive agents; rivastigmine

Indexed keywords

CETRIMIDE; LABRASOL; OCTANOIN; RIVASTIGMINE; CHOLINESTERASE INHIBITOR; EMULSION; EXCIPIENT;

EID: 84942892337     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2013.878857     Document Type: Article
Times cited : (113)

References (43)
  • 1
    • 77953912416 scopus 로고    scopus 로고
    • Strategy for effective brain drug delivery
    • Alam MI, Beg S, Samad A, et al. (2010). Strategy for effective brain drug delivery. Eur J Pharm Sci 40:385-403.
    • (2010) Eur J Pharm Sci , vol.40 , pp. 385-403
    • Alam, M.I.1    Beg, S.2    Samad, A.3
  • 3
    • 53549135761 scopus 로고    scopus 로고
    • A study of rivastigmine liposomes for delivery into the brain through intranasal route
    • Arumugam K, Subramanian GS, Mallayasamy SR, et al. (2008). A study of rivastigmine liposomes for delivery into the brain through intranasal route. Acta Pharm 58:287-97.
    • (2008) Acta Pharm , vol.58 , pp. 287-297
    • Arumugam, K.1    Subramanian, G.S.2    Mallayasamy, S.R.3
  • 4
    • 34548788545 scopus 로고    scopus 로고
    • Design, development and evaluation of novel nanoemulsion formulations for transdermal potential of celecoxib
    • Baboota S, Shakeel F, Ahuja A, et al. (2007). Design, development and evaluation of novel nanoemulsion formulations for transdermal potential of celecoxib. Acta Pharm 57:315-32.
    • (2007) Acta Pharm , vol.57 , pp. 315-332
    • Baboota, S.1    Shakeel, F.2    Ahuja, A.3
  • 5
    • 0041736287 scopus 로고    scopus 로고
    • Butyrylcholinesterase: Potential importance for the symptoms and progression of cognitive decline in people with dementia
    • Ballard CG, Perry EK. (2003). Butyrylcholinesterase: potential importance for the symptoms and progression of cognitive decline in people with dementia. Acta Neurol Taiwan 12:109-13.
    • (2003) Acta Neurol Taiwan , vol.12 , pp. 109-113
    • Ballard, C.G.1    Perry, E.K.2
  • 6
    • 79959923845 scopus 로고    scopus 로고
    • Strategies to formulate lipid-based drug delivery systems
    • Cannon JB. (2011). Strategies to formulate lipid-based drug delivery systems. Amer Pharm Rev 14:84-92.
    • (2011) Amer Pharm Rev , vol.14 , pp. 84-92
    • Cannon, J.B.1
  • 8
    • 2442671307 scopus 로고    scopus 로고
    • Impact of excipients on the absorption of P-glycoprotein substrates in vitro and in vivo
    • Cornaire G, Woodley J, Hermann P, et al. (2004). Impact of excipients on the absorption of P-glycoprotein substrates in vitro and in vivo. Int J Pharm 278:119-31.
    • (2004) Int J Pharm , vol.278 , pp. 119-131
    • Cornaire, G.1    Woodley, J.2    Hermann, P.3
  • 9
    • 0035073301 scopus 로고    scopus 로고
    • Modeling and comparison of dissolution profiles
    • Costa P, Lobo SJM. (2001). Modeling and comparison of dissolution profiles. Eur J Pharm Sci 13:123-33.
    • (2001) Eur J Pharm Sci , vol.13 , pp. 123-133
    • Costa, P.1    Lobo, S.J.M.2
  • 10
    • 1142297663 scopus 로고    scopus 로고
    • Characterization of caprylocaproyl macrogol glycerides based microemulsion drug delivery vehicles for an amphiphilic drug
    • Djordjevic L, Primorac M, Stupar M, Krajisnik D. (2004). Characterization of caprylocaproyl macrogol glycerides based microemulsion drug delivery vehicles for an amphiphilic drug. Int J Pharm 271:11-19.
    • (2004) Int J Pharm , vol.271 , pp. 11-19
    • Djordjevic, L.1    Primorac, M.2    Stupar, M.3    Krajisnik, D.4
  • 11
    • 0000009718 scopus 로고
    • Microemulsions
    • In: Swarbrick J, Boylan JC, eds. New York Marcel Dekker
    • Eccleston J. (1994). Microemulsions. In: Swarbrick J, Boylan JC, eds. Encyclopedia of pharmaceutical technology. Vol 9. New York: Marcel Dekker, 375-421.
    • (1994) Encyclopedia of Pharmaceutical Technology , vol.9 , pp. 375-421
    • Eccleston, J.1
  • 12
    • 84861115952 scopus 로고    scopus 로고
    • Development and evaluation of rivastigmine loaded chitosan nanoparticles for brain targeting
    • Fazil M, Shadab MD, Haque S, et al. (2012). Development and evaluation of rivastigmine loaded chitosan nanoparticles for brain targeting. Eur J Pharm Sci 47:6-15.
    • (2012) Eur J Pharm Sci , vol.47 , pp. 6-15
    • Fazil, M.1    Shadab, M.D.2    Haque, S.3
  • 13
    • 78650600381 scopus 로고    scopus 로고
    • Intranasal clobazam delivery in the treatment of status epilepticus
    • Florence K, Manisha L, Kumar BA, et al. (2011). Intranasal clobazam delivery in the treatment of status epilepticus. J Pharm Sci 100: 692-703.
    • (2011) J Pharm Sci , vol.100 , pp. 692-703
    • Florence, K.1    Manisha, L.2    Kumar, B.A.3
  • 14
    • 34548533271 scopus 로고    scopus 로고
    • Influence of formulation viscosity on drug absorption following nasal application in rats
    • Furubayashi T, Inoue D, Kamaguchi A, et al. (2007). Influence of formulation viscosity on drug absorption following nasal application in rats. Drug Metab Pharmacokinet 22:206-11.
    • (2007) Drug Metab Pharmacokinet , vol.22 , pp. 206-211
    • Furubayashi, T.1    Inoue, D.2    Kamaguchi, A.3
  • 15
    • 0036993145 scopus 로고    scopus 로고
    • Butyrylcholinesterase: An important new target in Alzheimer's disease therapy
    • Greig NH, Lahiri DK, Sambamurti K. (2002). Butyrylcholinesterase: an important new target in Alzheimer's disease therapy. Int Psychoger 14:77-91.
    • (2002) Int Psychoger , vol.14 , pp. 77-91
    • Greig, N.H.1    Lahiri, D.K.2    Sambamurti, K.3
  • 16
    • 0037532679 scopus 로고    scopus 로고
    • Cholinesterase inhibitors for the treatment of Alzheimer's disease: Getting on and staying on
    • Grossberg GT. (2003). Cholinesterase inhibitors for the treatment of Alzheimer's disease: getting on and staying on. Curr Ther Res 64: 216-35.
    • (2003) Curr Ther Res , vol.64 , pp. 216-235
    • Grossberg, G.T.1
  • 17
    • 77949897018 scopus 로고    scopus 로고
    • Microemulsions as drug delivery systems to improve the solubility and the bioavailability of poorly water-soluble drugs
    • He CX, He ZG, Gao JQ. (2010). Microemulsions as drug delivery systems to improve the solubility and the bioavailability of poorly water-soluble drugs. Expert Opin Drug Deliv 7:445-60.
    • (2010) Expert Opin Drug Deliv , vol.7 , pp. 445-460
    • He, C.X.1    He, Z.G.2    Gao, J.Q.3
  • 18
    • 29244485443 scopus 로고    scopus 로고
    • A new self-emulsifying formulation of itraconazole with improved dissolution and oral absorption
    • Hong JY, Kim JK, Song YK, et al. (2006). A new self-emulsifying formulation of itraconazole with improved dissolution and oral absorption. J Control Rel 110:332-8.
    • (2006) J Control Rel , vol.110 , pp. 332-338
    • Hong, J.Y.1    Kim, J.K.2    Song, Y.K.3
  • 19
    • 0031783879 scopus 로고    scopus 로고
    • Chitosan and its use as a pharmaceutical excipient
    • Illum L. (1998). Chitosan and its use as a pharmaceutical excipient. Pharm Res 15:1326-31.
    • (1998) Pharm Res , vol.15 , pp. 1326-1331
    • Illum, L.1
  • 20
    • 0034095651 scopus 로고    scopus 로고
    • Transport of drugs from the nasal cavity to the central nervous system
    • Illum L. (2000). Transport of drugs from the nasal cavity to the central nervous system. Eur J Pharm Sci 11:1-18.
    • (2000) Eur J Pharm Sci , vol.11 , pp. 1-18
    • Illum, L.1
  • 21
    • 0036896831 scopus 로고    scopus 로고
    • Nasal drug delivery: New developments and strategies
    • Illum L. (2002). Nasal drug delivery: new developments and strategies. Drug Dicov Today 7:1184-9.
    • (2002) Drug Dicov Today , vol.7 , pp. 1184-1189
    • Illum, L.1
  • 22
    • 0037459005 scopus 로고    scopus 로고
    • Nasal drug delivery - Possibilities, problems and solutions
    • Illum L. (2003). Nasal drug delivery - possibilities, problems and solutions. J Control Rel, 87:187-98.
    • (2003) J Control Rel , vol.87 , pp. 187-198
    • Illum, L.1
  • 23
    • 34248205304 scopus 로고    scopus 로고
    • Nasal drug delivery systems - Factors affecting and applications
    • Jadhav KR, Gambhire MN, Shaikh IM, et al. (2007). Nasal drug delivery systems - factors affecting and applications. Curr Drug Ther 2: 227-38.
    • (2007) Curr Drug Ther , vol.2 , pp. 227-238
    • Jadhav, K.R.1    Gambhire, M.N.2    Shaikh, I.M.3
  • 24
    • 79952021431 scopus 로고    scopus 로고
    • Design and evaluation of microemulsion based drug delivery system
    • Jadhav KR, Shetye SL, Kadam VJ. (2010). Design and evaluation of microemulsion based drug delivery system. Int J Adv Pharm Sci 1: 156-66.
    • (2010) Int J Adv Pharm Sci , vol.1 , pp. 156-166
    • Jadhav, K.R.1    Shetye, S.L.2    Kadam, V.J.3
  • 25
    • 70449559092 scopus 로고    scopus 로고
    • Preparation, characterization and in-vitro evaluation of sun flower oil-tween 80-glycerol-based microemulsion formulation of a BCS class-II drug
    • Kamila MM, Mondal N, Gupta BK, Ghosh LK. (2009). Preparation, characterization and in-vitro evaluation of sun flower oil-tween 80-glycerol-based microemulsion formulation of a BCS class-II drug. Lat Am J Pharm 28:622-7.
    • (2009) Lat Am J Pharm , vol.28 , pp. 622-627
    • Kamila, M.M.1    Mondal, N.2    Gupta, B.K.3    Ghosh, L.K.4
  • 26
    • 0037123703 scopus 로고    scopus 로고
    • Microemulsion formulation for enhanced absorption of poorly soluble drugs I. Prescription design
    • Kawakami K, Yoshikawa T, Moroto Y, et al. (2002). Microemulsion formulation for enhanced absorption of poorly soluble drugs. I. Prescription design. J Control Rel 81:65-74.
    • (2002) J Control Rel , vol.81 , pp. 65-74
    • Kawakami, K.1    Yoshikawa, T.2    Moroto, Y.3
  • 27
    • 84874484429 scopus 로고    scopus 로고
    • Mucoadhesive chitosan coated cationic microemulsion of dexamethasone for ocular delivery: In vitro and in vivo evaluation
    • Kesavan K, Kant S, Singh PN, Pandit JK. (2013). Mucoadhesive chitosan coated cationic microemulsion of dexamethasone for ocular delivery: in vitro and in vivo evaluation. Curr Eye Res 38: 342-52.
    • (2013) Curr Eye Res , vol.38 , pp. 342-352
    • Kesavan, K.1    Kant, S.2    Singh, P.N.3    Pandit, J.K.4
  • 29
    • 65749099862 scopus 로고    scopus 로고
    • Formulation and characterization of nanoemulsion-based drug delivery system of risperidone
    • Kumar M, Pathak K, Misra A. (2009). Formulation and characterization of nanoemulsion-based drug delivery system of risperidone. Drug Dev Ind Pharm 35:387-95.
    • (2009) Drug Dev Ind Pharm , vol.35 , pp. 387-395
    • Kumar, M.1    Pathak, K.2    Misra, A.3
  • 30
    • 0034614208 scopus 로고    scopus 로고
    • Microemulsion based media as novel drug delivery systems
    • Lawrence MJ, Rees GD. (2000). Microemulsion based media as novel drug delivery systems. Adv Drug Del Rev 45:89-121.
    • (2000) Adv Drug Del Rev , vol.45 , pp. 89-121
    • Lawrence, M.J.1    Rees, G.D.2
  • 31
    • 84937013344 scopus 로고    scopus 로고
    • 4th ed. Philadelphia: Lippincott Williams & Wilkins
    • Lazenby RB. (2010). Handbook of pathophysiology. 4th ed. Philadelphia: Lippincott Williams & Wilkins, 286-9.
    • (2010) Handbook of Pathophysiology , pp. 286-289
    • Lazenby, R.B.1
  • 32
    • 79952030531 scopus 로고    scopus 로고
    • Design and development of carbamazepine mucoadhesive microemulsion for intranasal delivery: An ex vivo study
    • Mandal S, Mandal DS. (2010). Design and development of carbamazepine mucoadhesive microemulsion for intranasal delivery: an ex vivo study. Int J Pharm Sci Rev Res 3:56-60.
    • (2010) Int J Pharm Sci Rev Res , vol.3 , pp. 56-60
    • Mandal, S.1    Mandal, D.S.2
  • 33
    • 77954310517 scopus 로고    scopus 로고
    • Preparation and evaluation of fexofenadine microemulsions for intranasal delivery
    • Piao HM, Balakrishna P, Cho HJ, et al. (2010). Preparation and evaluation of fexofenadine microemulsions for intranasal delivery. Int J Pharm 395:309-16.
    • (2010) Int J Pharm , vol.395 , pp. 309-316
    • Piao, H.M.1    Balakrishna, P.2    Cho, H.J.3
  • 34
    • 0343487750 scopus 로고    scopus 로고
    • Formulation of self emulsifying drug delivery systems
    • Pouton CW. (1997). Formulation of self emulsifying drug delivery systems. Adv Drug Del Rev 25:47-58.
    • (1997) Adv Drug Del Rev , vol.25 , pp. 47-58
    • Pouton, C.W.1
  • 35
    • 84855381477 scopus 로고    scopus 로고
    • Carbamazepine mucoadhesive nanoemulgel (MNEG) as brain targeting delivery system via the olfactory mucosa
    • Samia O, Hanan R, Kamal ET. (2012). Carbamazepine mucoadhesive nanoemulgel (MNEG) as brain targeting delivery system via the olfactory mucosa. Drug Del 19:58-67.
    • (2012) Drug Del , vol.19 , pp. 58-67
    • Samia, O.1    Hanan, R.2    Kamal, E.T.3
  • 36
    • 33644777424 scopus 로고    scopus 로고
    • Spraydried mucoadhesive microspheres: Preparatiion and transport through nasal cell monolayer
    • Saraparn H, Vimolmas L, Narueporn S, Garnpimol CR. (2006). Spraydried mucoadhesive microspheres: preparatiion and transport through nasal cell monolayer. AAPS Pharm Sci Tech 7:E79-88.
    • (2006) AAPS Pharm Sci Tech , vol.7 , pp. E79-88
    • Saraparn, H.1    Vimolmas, L.2    Narueporn, S.3    Garnpimol, C.R.4
  • 37
    • 0042020173 scopus 로고    scopus 로고
    • Treatment of Alzheimer's disease: Current status and new perspectives
    • Scarpini E, Scheltens P, Feldman H. (2003). Treatment of alzheimer's disease: current status and new perspectives. Lancet Neurol 2:539-47.
    • (2003) Lancet Neurol , vol.2 , pp. 539-547
    • Scarpini, E.1    Scheltens, P.2    Feldman, H.3
  • 38
    • 0034718157 scopus 로고    scopus 로고
    • Alzheimer's amyloid fibrils: Structure and assembly
    • Serpell LC. (2000). Alzheimer's amyloid fibrils: structure and assembly. Biochim Biophys Acta 1502:16-30.
    • (2000) Biochim Biophys Acta , vol.1502 , pp. 16-30
    • Serpell, L.C.1
  • 39
    • 0035052725 scopus 로고    scopus 로고
    • Improved drug delivery using microemulsions: Rationale, recent progress and new horizons
    • Shah DO, Bagwe RP, Kanicky JR, et al. (2001). Improved drug delivery using microemulsions: rationale, recent progress and new horizons. Crit Rev Ther Drug Carrier Syst 18:77-140.
    • (2001) Crit Rev Ther Drug Carrier Syst , vol.18 , pp. 77-140
    • Shah, D.O.1    Bagwe, R.P.2    Kanicky, J.R.3
  • 40
    • 0038721593 scopus 로고    scopus 로고
    • A review of rivastigmine: A reversible cholinesterase inhibitor
    • Williams BR, Nazarians A, Gill MA. (2003). A review of rivastigmine: a reversible cholinesterase inhibitor. Clin Ther 25: 1634-53.
    • (2003) Clin Ther , vol.25 , pp. 1634-1653
    • Williams, B.R.1    Nazarians, A.2    Gill, M.A.3
  • 41
    • 37449020071 scopus 로고    scopus 로고
    • The molecular pathology of Alzheimer's disease
    • Yates D, McLoughlin DM. (2008). The molecular pathology of Alzheimer's disease. Psychiatry 7:1-5.
    • (2008) Psychiatry , vol.7 , pp. 1-5
    • Yates, D.1    McLoughlin, D.M.2
  • 42
    • 84894370625 scopus 로고    scopus 로고
    • Contact angle and wetting properties
    • In: Bracco G, Holst B, eds. New York: Springer Berlin-Heidelberg
    • Yuan Y, Lee TR. (2013). Contact angle and wetting properties. In: Bracco G, Holst B, eds. Surface science techniques. New York: Springer Berlin-Heidelberg, 3-29.
    • (2013) Surface Science Techniques , pp. 3-29
    • Yuan, Y.1    Lee, T.R.2
  • 43
    • 1842789813 scopus 로고    scopus 로고
    • Preparation of nimodipine-loaded microemulsion for intranasal delivery and evaluation on the targeting efficiency to the brain
    • Zhang Q, Jinag X, Jinag W, et al. (2004). Preparation of nimodipine-loaded microemulsion for intranasal delivery and evaluation on the targeting efficiency to the brain. Int J Pharm 275:85-96.
    • (2004) Int J Pharm , vol.275 , pp. 85-96
    • Zhang, Q.1    Jinag, X.2    Jinag, W.3


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