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Volumn 19, Issue 1, 2012, Pages 58-67

Carbamazepine Mucoadhesive Nanoemulgel (MNEG) as brain targeting delivery system via the olfactory mucosa

Author keywords

brain targeting; carbamazepine; delivery via olfactory mucosa; Nanoemulgel; uptake of drug by liposomes as biomembrane model

Indexed keywords

CARBAMAZEPINE; DRUG CARRIER; LABRASOL; LIPOSOME; MUCOADHESIVE NANOEMULGEL; OLEIC ACID; UNCLASSIFIED DRUG; XANTHAN;

EID: 84855381477     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2011.644349     Document Type: Article
Times cited : (52)

References (70)
  • 1
    • 17844393389 scopus 로고    scopus 로고
    • Comparative study of different silymarin formulations: Formulation, characterisation and in vitro/in vivo evaluation
    • DOI 10.2174/1567201052772870
    • Abrol S, Trehan A, Katare OP. 2005. Comparative study of diferent silymarin formulations: formulation, characterization and in vitro/in vivo evaluation. Curr Drug Deliv, 2, 45-51. (Pubitemid 40590920)
    • (2005) Current Drug Delivery , vol.2 , Issue.1 , pp. 45-51
    • Abrol, S.1    Trehan, A.2    Katare, O.P.3
  • 2
    • 25144449201 scopus 로고    scopus 로고
    • Effect of carbamazepine on serum lipids and liver function tests
    • Aggarwal A, Kumar M, Faridi MM. 2005. Efect of carbamazepine on serum lipids and liver function tests. Indian Pediatr, 42(9), 913-918. (Pubitemid 41345646)
    • (2005) Indian Pediatrics , vol.42 , Issue.9 , pp. 913-918
    • Aggarwal, A.1    Kumar, M.2    Faridi, M.M.A.3
  • 3
    • 0038061596 scopus 로고    scopus 로고
    • Formulation of intravenous Carbamazepine emulsions by SolEmuls® technology
    • DOI 10.1016/S0939-6411(03)00028-6
    • Akkar A, Müller RH. 2003. Formulation of intravenous carbamazepine emulsions by SolEmuls® technology. Eur J Pharm Biopharm, 55, 305-312. (Pubitemid 36561557)
    • (2003) European Journal of Pharmaceutics and Biopharmaceutics , vol.55 , Issue.3 , pp. 305-312
    • Akkar, A.1    Muller, R.H.2
  • 4
    • 60749111451 scopus 로고    scopus 로고
    • Mucoadhesive polymeric platforms for controlled drug delivery
    • Andrew GP, Laverty TP, Jones DS. 2009. Mucoadhesive polymeric platforms for controlled drug delivery. Eur J Pharm Biopharm, 71(3), 505-518.
    • (2009) Eur J Pharm Biopharm , vol.71 , Issue.3 , pp. 505-518
    • Andrew, G.P.1    Laverty, T.P.2    Jones, D.S.3
  • 5
    • 0014094680 scopus 로고
    • Evalustion of a new convulsant for anticonvulsant screening
    • Banziger R, Hane D. 1967. Evalustion of a new convulsant for anticonvulsant screening. Archiv Int Pharmacodyn, 167, 245-249.
    • (1967) Archiv Int Pharmacodyn , vol.167 , pp. 245-249
    • Banziger, R.1    Hane, D.2
  • 6
    • 0036753845 scopus 로고    scopus 로고
    • Development of o/w emulsion formulation for carbamazepine by using modified cyclodextrins
    • Becirevic-Lacan M, Jug M, Bacic-Vrca V, Cetina-Cizmek B. 2002. Development of o/w emulsion formulation for carbamazepine by using modifed cyclodextrins. Acta Pharm, 52, 149-159. (Pubitemid 35285062)
    • (2002) Acta Pharmaceutica , vol.52 , Issue.3 , pp. 149-159
    • Becirevic-Lacan, M.1    Jug, M.2    Bacic-Vrca, V.3    Cetina-Cizmek, B.4
  • 7
    • 0023543709 scopus 로고
    • Molecular dosimetry of DNA adduct formation and cell toxicity in rat nasal mucosa following exposure to the tobacco specific nitrosamine 4-(N-methyl-N-nitrosamine)-1-(3-pyridyl)-1-butanone and their relationship to induction of neoplasia
    • Belinsky SA, Walker VE, Maronpot RR, Swenberg JA, Anderson MW. 1987. Molecular dosimetry and DNA adduct formation and toxicity in rat nasal mucosa following exposure to the tobacco specifc nitrosamine 4-(N-methyl-N-nitrosamino) -1-(3-pyridyl)-1-butanone and their relationship to induction of neoplasia. Cancer Res, 47, 6058-6065. (Pubitemid 18018754)
    • (1987) Cancer Research , vol.47 , Issue.22 , pp. 6058-6065
    • Belinsky, S.A.1    Walker, V.E.2    Maronpot, R.R.3    Swenberg, J.A.4    Anderson, M.W.5
  • 8
    • 0021963276 scopus 로고
    • Bioadhesive polymers as platforms for oral controlled drug delivery II. Synthesis and evaluation of some swelling water-insoluble bioadhesive polymers
    • Ch'ng HS, Park H, Kelly P, Robinoson JR. 1985. Bioadhesive polymers as platforms for oral controlled drug delivery II. Synthesis and evaluation of some swelling water-insoluble bioadhesive polymers. J Pharm Sci, 74, 339-405.
    • (1985) J Pharm Sci , vol.74 , pp. 339-405
    • Ch'Ng, H.S.1    Park, H.2    Kelly, P.3    Robinoson, J.R.4
  • 9
    • 0030991550 scopus 로고    scopus 로고
    • Distribution of antihistamines into the CSF following intranasal delivery
    • DOI 10.1002/(SICI)1099-081X(199705)18:4<335::AID-BDD22>3.0.CO;2-W
    • Chou KJ, Donovan MD. 1997. Distribution of antihistamines into the CSF following intranasal delivery. Biopharm Drug dispos, 18, 335-346 (Pubitemid 27241149)
    • (1997) Biopharmaceutics and Drug Disposition , vol.18 , Issue.4 , pp. 335-346
    • Chou, K.-J.1    Donovan, M.D.2
  • 11
    • 1942518298 scopus 로고    scopus 로고
    • Tocol emulsions for drug solubilization and parenteral delivery
    • DOI 10.1016/j.addr.2003.12.005, PII S0169409X04000432
    • Constantinides PP, Tustian A, Kessler DR. 2004. Tocol emulsions for drug solubilization and parenteral delivery. Adv Drug Deliv Rev, 56, 1243-1255. (Pubitemid 38510472)
    • (2004) Advanced Drug Delivery Reviews , vol.56 , Issue.9 , pp. 1243-1255
    • Constantinides, P.P.1    Tustian, A.2    Kessler, D.R.3
  • 12
    • 34147178396 scopus 로고    scopus 로고
    • Polysaccharide hydrogels for modified release formulations
    • DOI 10.1016/j.jconrel.2007.01.004, PII S0168365907000399
    • Coviello T, Matricardi P, Marianecci C, Alhaique F. 2007. Polysaccharide hydrogels for modifed release formulations. J Control Rel, 119, 5-24. (Pubitemid 46561537)
    • (2007) Journal of Controlled Release , vol.119 , Issue.1 , pp. 5-24
    • Coviello, T.1    Matricardi, P.2    Marianecci, C.3    Alhaique, F.4
  • 13
    • 0033839330 scopus 로고    scopus 로고
    • Transfer of dopamine in the olfactory pathway following nasal administration in mice
    • Dahlin M, Bergman U, Jansson B, Björk E, Brittebo E. 2000. Transfer of dopamine in the olfactory pathway following nasal administration in mice. Pharm Res, 17(6), 737-42.
    • (2000) Pharm Res , vol.17 , Issue.6 , pp. 737-742
    • Dahlin, M.1    Bergman, U.2    Jansson, B.3    Björk, E.4    Brittebo, E.5
  • 14
    • 0031703807 scopus 로고    scopus 로고
    • Development of diclofenac sodium controlled release solid dispersion powders and capsules by freeze drying technique using ethylcellulose and chitosan as carriers
    • Dangprasirt P, Pongwai S. 1998. Development of diclofnac sodium controlled release solid dispersion powders and capsules by freeze drying technique using ethylcellulose and chitosan as carriers. Drug Dev Ind Pharm, 24, 947-953. (Pubitemid 28470971)
    • (1998) Drug Development and Industrial Pharmacy , vol.24 , Issue.10 , pp. 947-953
    • Dangprasirt, P.1    Pongwai, S.2
  • 15
    • 33644984488 scopus 로고    scopus 로고
    • Methods to assess in vitro drug release from injectable polymeric particulate systems
    • D'Souza SS, DeLuca PP. 2006. Methods to assess in vitro drug release from injectable polymeric particulate systems. Pharm Res, 23, 460-474.
    • (2006) Pharm Res , vol.23 , pp. 460-474
    • D'Souza, S.S.1    Deluca, P.P.2
  • 16
    • 0026769129 scopus 로고
    • Microspheres as a nasal delivery system for peptides
    • Edman P, Bjork E, Ryden L. 1992. Microspheres as a nasal delivery system for peptides. J Control Rel, 21, 165-172.
    • (1992) J Control Rel , vol.21 , pp. 165-172
    • Edman, P.1    Bjork, E.2    Ryden, L.3
  • 18
    • 67549104175 scopus 로고    scopus 로고
    • Intranasal microemulsion of sildenafl citrate: In vitro evaluation and in vivo pharmacokinetic study in rabbits
    • Elshafeey AH, Bendas ER, Mohamed OH. 2009. Intranasal microemulsion of sildenafl citrate: In vitro evaluation and in vivo pharmacokinetic study in rabbits. AAPS Pharm Sci Tech, 10 (2), 361-367.
    • (2009) AAPS Pharm Sci Tech , vol.10 , Issue.2 , pp. 361-367
    • Elshafeey, A.H.1    Bendas, E.R.2    Mohamed, O.H.3
  • 19
    • 79952298246 scopus 로고    scopus 로고
    • Chemical and pharmacological study of Cymbopogon Proximus volatile oil
    • El Tahir KEH, Abdel-Kader M. 2008. Chemical and pharmacological study of Cymbopogon Proximus volatile oil. Res J Med Plants, 2(2), 52-60.
    • (2008) Res J Med Plants , vol.2 , Issue.2 , pp. 52-60
    • Tahir Keh, E.1    Abdel-Kader, M.2
  • 20
    • 0035041044 scopus 로고    scopus 로고
    • Liposomal formulations of cyclosporin A: A biophysical approach to pharmacokinetics and pharmacodynamics
    • Fahr A, Seelig J. 2001. Liposomal formulations of Cyclosporin A: A biophysical approach to pharmacokinetics and pharmacodynamics. Crit Rev Ter Drug Carr Syst, 18(2), 141-172. (Pubitemid 32378146)
    • (2001) Critical Reviews in Therapeutic Drug Carrier Systems , vol.18 , Issue.2 , pp. 141-172
    • Fahr, A.1    Seelig, J.2
  • 22
    • 24644453083 scopus 로고    scopus 로고
    • Transfer of lipophilic drugs between liposomal membranes and biological interfaces: Consequences for drug delivery
    • DOI 10.1016/j.ejps.2005.05.012, PII S0928098705001922
    • Fahr A, van Hoogevest P, May S, Bergstrand N, Leigh MLS. 2005. Transfer of lipophilic drugs between liposomal membranes and biological interfaces: Consequences for drug delivery. Eur J Pharm Sci, 26, 251-265. (Pubitemid 41278632)
    • (2005) European Journal of Pharmaceutical Sciences , vol.26 , Issue.3-4 , pp. 251-265
    • Fahr, A.1    Hoogevest, P.V.2    May, S.3    Bergstrand, N.4    Leigh, M.L.S.5
  • 23
    • 0034315817 scopus 로고    scopus 로고
    • Xanthan gum: Production, recovery, and properties
    • DOI 10.1016/S0734-9750(00)00050-1, PII S0734975000000501
    • Garcia-Ochoa F, Santos VE, Casa JA, Gomez E. 2000. Xanthan gum: production, recovery, and properties. Biotechnol Adv, 18, 549-579. (Pubitemid 32122510)
    • (2000) Biotechnology Advances , vol.18 , Issue.7 , pp. 549-579
    • Garcia-Ochoa, F.1    Santos, V.E.2    Casas, J.A.3    Gomez, E.4
  • 24
    • 0012129372 scopus 로고    scopus 로고
    • Microemulsions in the pharmaceutical feld: Perspectives and applications
    • New York marcel Dekker
    • Gasco MR. (1997). Microemulsions in the pharmaceutical feld: perspectives and applications," in Industrial Applications of Microemulsions, New York, marcel Dekker, 97-122.
    • (1997) Industrial Applications of Microemulsions , pp. 97-122
    • Gasco, M.R.1
  • 26
    • 0034255833 scopus 로고    scopus 로고
    • Mathematical modeling of drug release from microemulsions: Theory in comparison with experiments
    • DOI 10.1006/jcis.2000.6945
    • Grassi M, Coceani N, Magarotto L. 2000. Mathematical modeling of drug release from microemulsions: theory in comparison with experiments. J Colloid Interface Sci, 228, 141-150. (Pubitemid 30483383)
    • (2000) Journal of Colloid and Interface Science , vol.228 , Issue.1 , pp. 141-150
    • Grassi, M.1    Coceani, N.2    Magarotto, L.3
  • 27
    • 0015549559 scopus 로고
    • Cell dynamics in the olfactory mucosa
    • Graziadei PPC. 1973. Cell dynamics in the olfactory mucosa. Tissue and Cell, 5, 113-131.
    • (1973) Tissue and Cell , vol.5 , pp. 113-131
    • Graziadei, P.P.C.1
  • 28
    • 0023917757 scopus 로고    scopus 로고
    • Binding of acrylic polymers to mucin/epithelial surfaces: Structure-property relationships
    • Gu JM, Robinson JR, Leung SH. 1998. Binding of acrylic polymers to mucin/epithelial surfaces: structure-property relationships. Crit Rev Ter Drug Carr Syst, 5, 21-67.
    • (1998) Crit Rev ter Drug Carr Syst , vol.5 , pp. 21-67
    • Gu, J.M.1    Robinson, J.R.2    Leung, S.H.3
  • 29
    • 33645968393 scopus 로고    scopus 로고
    • Trends in mucoadhesive analysis
    • Harding SE. 2006. Trends in mucoadhesive analysis. Trends Food Sci Tech, 17 (5), 255-262.
    • (2006) Trends Food Sci Tech , vol.17 , Issue.5 , pp. 255-262
    • Harding, S.E.1
  • 30
    • 0028946239 scopus 로고
    • In vitro evaluation of drug release kinetics from liposomes by fractional dialysis
    • Henriksen I, Sande SA, Smistad G, Agren T, Karlsen J. 1995. In vitro evaluation of drug release kinetics from liposomes by fractional dialysis. Int J Pharm, 119, 231-238.
    • (1995) Int J Pharm , vol.119 , pp. 231-238
    • Henriksen, I.1    Sande, S.A.2    Smistad, G.3    Agren, T.4    Karlsen, J.5
  • 31
    • 0025881509 scopus 로고
    • New approaches to drug design and delivery based on drug-membrane interactions
    • Herbette L, Rhodes DG, Preston Mason R. 1991. New approaches to drug design and delivery based on drug-membrane interactions. Drug Design Deliv, 7, 75-118.
    • (1991) Drug Design Deliv , vol.7 , pp. 75-118
    • Herbette, L.1    Rhodes, D.G.2    Preston Mason, R.3
  • 32
    • 1042269557 scopus 로고    scopus 로고
    • Is nose-to-brain transport of drugs in man a reality?
    • DOI 10.1211/0022357022539
    • Illum L. 2004. Is nose-to-brain transport of drugs in man a reality? J Pharm Pharmacol, 56(1), 3-17. (Pubitemid 38195323)
    • (2004) Journal of Pharmacy and Pharmacology , vol.56 , Issue.1 , pp. 3-17
    • Illum, L.1
  • 33
    • 33750121902 scopus 로고    scopus 로고
    • Pharmacotherapy of the epilepsies
    • Brunton LL, Lazo JS, Parker KL, ed New York: McGraw-Hill 12th ed
    • James O, McNamara. (2006). Pharmacotherapy of the epilepsies. In: Brunton LL, Lazo JS, Parker KL, ed. Goodman & Gilman's, The pharmacological basis of therapeutics. New York: McGraw-Hill, 12th ed, 501-525.
    • (2006) Goodman & Gilman's, The Pharmacological Basis of Therapeutics , pp. 501-525
    • James, O.M.1
  • 34
    • 0037123701 scopus 로고    scopus 로고
    • Microemulsion formulation for enhanced absorption of poorly soluble drugs: II. In vivo study
    • DOI 10.1016/S0168-3659(02)00050-0, PII S0168365902000500
    • Kawakami K, Yoshikawa T, Moroto Y, Kanaoka E, Takahashi K, Nishihara Y, Masuda K. 2002. Microemulsion formulation for enhanced absorption of poorly soluble drugs II. In vivo study. J Control Rel, 81, 75-82. (Pubitemid 34454851)
    • (2002) Journal of Controlled Release , vol.81 , Issue.1-2 , pp. 75-82
    • Kawakami, K.1    Yoshikawa, T.2    Hayashi, T.3    Nishihara, Y.4    Masuda, K.5
  • 35
    • 34547971125 scopus 로고    scopus 로고
    • Carbamazepine parenteral nanoemulsions prepared by spontaneous emulsification process
    • DOI 10.1016/j.ijpharm.2007.05.004, PII S0378517307003869
    • Kelmann RG, Kuminek G, Teixeira HF, Koester LS. 2007. Carbamazepine parenteral nanoemulsions prepared by spontaneous emulsifcation process. Int J Pharm, 342(1-2), 231-239. (Pubitemid 47271896)
    • (2007) International Journal of Pharmaceutics , vol.342 , Issue.1-2 , pp. 231-239
    • Kelmann, R.G.1    Kuminek, G.2    Teixeira, H.F.3    Koester, L.S.4
  • 36
    • 0033988596 scopus 로고    scopus 로고
    • Physicochemical properties and bioavailability of carbamazepine polymorphs and dihydrate
    • DOI 10.1016/S0378-5173(99)00315-4, PII S0378517399003154
    • Kobayashi Y, Itai S, Yamamoto K. 2000. Pysicochemical propreties and bioavailability of carbamazepine polymorphs and dehydrate. Int J Pharm, 193, 137-146. (Pubitemid 30001856)
    • (2000) International Journal of Pharmaceutics , vol.193 , Issue.2 , pp. 137-146
    • Kobayashi, Y.1    Ito, S.2    Itai, S.3    Yamamoto, K.4
  • 38
    • 0034614208 scopus 로고    scopus 로고
    • Microemulsion-based media as novel drug delivery systems
    • Lawrence MJ, Rees GD. 2000. Microemulsion-based media as novel drug delivery systems. Adv Drug Deliv Rev, 45, 89-121.
    • (2000) Adv Drug Deliv Rev , vol.45 , pp. 89-121
    • Lawrence, M.J.1    Rees, G.D.2
  • 39
    • 55449090690 scopus 로고    scopus 로고
    • Anticonvulsant hypersensitivity syndrome: Clinical and laboratory features
    • Mansur AT, Pekcan Yaar S, Göktay F. 2008. Anticonvulsant hypersensitivity syndrome: clinical and laboratory features. Int J Dermatol, 11, 1184-1189.
    • (2008) Int J Dermatol , vol.11 , pp. 1184-1189
    • Mansur, A.T.1    Pekcan Yaar, S.2    Göktay, F.3
  • 40
    • 70350774065 scopus 로고    scopus 로고
    • Preparation and Characterization of Oil in Water Nano-Reservoir Systems for Improved Oral Delivery of Atorvastatin
    • Mustafa G, Khan Z, Bansal T, Talegaonkar S. 2009. Preparation and Characterization of Oil in Water Nano-Reservoir Systems for Improved Oral Delivery of Atorvastatin. Curr Nanosci, 5, 428-440.
    • (2009) Curr Nanosci , vol.5 , pp. 428-440
    • Mustafa, G.1    Khan, Z.2    Bansal, T.3    Talegaonkar, S.4
  • 41
    • 0029049604 scopus 로고
    • In vitro assessment of bioadhesion for periodontal and buccal drug delivery
    • Needleman IG, Smales FC. 1995. In vitro assessment of bioadhesion for periodontal and buccal drug delivery. Biomaterials, 16, 617-624.
    • (1995) Biomaterials , vol.16 , pp. 617-624
    • Needleman, I.G.1    Smales, F.C.2
  • 42
    • 70350014908 scopus 로고    scopus 로고
    • Retrospective analysis of 32 pediatric patients with anticonvulsant hypersensitivity syndrome (ACHSS)
    • Newell BD, Moinfar M, Mancini AJ, Nopper AJ. 2009. Retrospective analysis of 32 pediatric patients with anticonvulsant hypersensitivity syndrome (ACHSS). Pediatr Dermatol, 26(5), 536-546.
    • (2009) Pediatr Dermatol , vol.26 , Issue.5 , pp. 536-546
    • Newell, B.D.1    Moinfar, M.2    Mancini, A.J.3    Nopper, A.J.4
  • 44
    • 0037026275 scopus 로고    scopus 로고
    • Lecithin microemulsions for the topical administration of ketoprofen: Percutaneous adsorption through human skin and in vivo human skin tolerability
    • DOI 10.1016/S0378-5173(02)00295-8, PII S0378517302002958
    • Paolino D, Ventura CA, Nisticò S, Puglisi G, Fresta M. 2002. Lecithin microemulsions for the topical administration of ketoprofen: percutaneous adsorption through human skin and in vivo human skin tolerability. Int J Pharm, 244(1-2), 21-31. (Pubitemid 35245443)
    • (2002) International Journal of Pharmaceutics , vol.244 , Issue.1-2 , pp. 21-31
    • Paolino, D.1    Ventura, C.A.2    Nistico, S.3    Puglisi, G.4    Fresta, M.5
  • 46
    • 0021904208 scopus 로고
    • Analysis of Fickian and non Fickian drug release from Polymers
    • Peppas NA. 1985. Analysis of Fickian and non Fickian drug release from Polymers. Pharm Acta Helv, 60, 110-111.
    • (1985) Pharm Acta Helv , vol.60 , pp. 110-111
    • Peppas, N.A.1
  • 47
    • 0022402037 scopus 로고
    • Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues
    • Peppas NA, Buri PA. 1985. Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues. J Control Rel, 2, 257-275. (Pubitemid 16195943)
    • (1985) Journal of Controlled Release , vol.VOL. 2 , pp. 257-275
    • Peppas, N.A.1    Buri, P.A.2
  • 48
    • 78651593283 scopus 로고    scopus 로고
    • Removal of ciprofoxazin and carbamazepine by adsorption on functionalized mesoporous silicates
    • Punyapalakul P, Sitthisorn T. 2010. Removal of ciprofoxazin and carbamazepine by adsorption on functionalized mesoporous silicates. World Academy of Science, Engineering and Technology, 69, 546-550.
    • (2010) World Academy of Science, Engineering and Technology , vol.69 , pp. 546-550
    • Punyapalakul, P.1    Sitthisorn, T.2
  • 49
    • 0033153256 scopus 로고    scopus 로고
    • Seizure disorders in mutant mice: Relevance to human epilepsies
    • DOI 10.1016/S0959-4388(99)80041-5
    • Puranam RS, McNamara K. 1999. Seizure disorder in mutant mice: relevance to human epilepsies. Curr Opin Neurobiol, 9, 281-287. (Pubitemid 29267597)
    • (1999) Current Opinion in Neurobiology , vol.9 , Issue.3 , pp. 281-287
    • Puranam, R.S.1    McNamara, J.O.2
  • 51
    • 0347028284 scopus 로고    scopus 로고
    • Isolation of a Natural Mutant in Castor with High Oleic/Low Ricinoleic Acid Content in the Oil
    • Rojas-Barros P, De Haro A, Munoz J, Fernandez-Martinez JM. 2004. Isolation of a natural mutant in castor with high oleic/low ricinoleic acid content in the oil. Crop Sci, 44(1), 76-80. (Pubitemid 38051605)
    • (2004) Crop Science , vol.44 , Issue.1 , pp. 76-80
    • Rojas-Barros, P.1    De Haro, A.2    Munoz, J.3    Fernandez-Martinez, J.M.4
  • 52
    • 0024405661 scopus 로고
    • Characterization of the total lipid and fatty acid composition of rat olfactory mucosa
    • Russell Y, Evans P, Dodd GH. 1989. Characterization of the total lipid and fatty acid composition of rat olfactory mucosa. J Lipid Res, 30, 877-884. (Pubitemid 19167309)
    • (1989) Journal of Lipid Research , vol.30 , Issue.6 , pp. 877-884
    • Russell, Y.1    Evans, P.2    Dodd, G.H.3
  • 53
    • 0028323017 scopus 로고
    • Direct drug transport from the rat nasal cavity to the cerebrospinal fluid: The relation to the dissociation of the drug
    • Sakane T, Akizuki T, Yamashita S, Sezaki H, Nadai T. 1994. Direct drug transport from the rat nasal cavity to the cerebrospinal fuid: the relation to the dissociation of the drug. J Pharm Pharmacol, 46(5), 378-379. (Pubitemid 24140941)
    • (1994) Journal of Pharmacy and Pharmacology , vol.46 , Issue.5 , pp. 378-379
    • Sakane, T.1    Akizuki, M.2    Yamashita, S.3    Sezaki, H.4    Nadai, T.5
  • 54
    • 0030734317 scopus 로고    scopus 로고
    • Rotating dialysis cell as in vitro release method for oily parenteral depot solutions
    • DOI 10.1016/S0378-5173(97)00229-9, PII S0378517397002299
    • Schultz K, Mollgaard B, Frokjaer S, Larsen C. 1997. Rotating dialysis cell as in vitro release method for oily parenteral depot solutions. Int J Pharm, 157, 163-169. (Pubitemid 27471168)
    • (1997) International Journal of Pharmaceutics , vol.157 , Issue.2 , pp. 163-169
    • Schultz, K.1    Mollgaard, B.2    Frokjaer, S.3    Larsen, C.4
  • 55
    • 0036771080 scopus 로고    scopus 로고
    • Physicochemical characterization of solid dispersions of carbamazepine formulated by supercritical carbon dioxide and conventional solvent evaporation method
    • DOI 10.1002/jps.10186
    • Sethia S, Squillante E. 2002. Physicochemical characterization of solid dispersions of carbamazepine formulated by supercritical carbon dioxide and conventional solvent evaporation method. J Pharm Sci, 91, 1948-1957. (Pubitemid 36254931)
    • (2002) Journal of Pharmaceutical Sciences , vol.91 , Issue.9 , pp. 1948-1957
    • Sethia, S.1    Squillante, E.2
  • 57
    • 33644626453 scopus 로고    scopus 로고
    • Transdermal drug delivery using microemulsion and aqueous systems: Infuence of skin storage conditions on the in vitro permeability of diclofenac from aqueous vehicle systems
    • Sintov AC, Botner S. 2006. Transdermal drug delivery using microemulsion and aqueous systems: infuence of skin storage conditions on the in vitro permeability of diclofenac from aqueous vehicle systems. Int J Pharm, 311, 55-62.
    • (2006) Int J Pharm , vol.311 , pp. 55-62
    • Sintov, A.C.1    Botner, S.2
  • 59
    • 65549152056 scopus 로고    scopus 로고
    • Artifcial membrane technologies to assess transfer and permeation of drugs in drug discovery
    • Taylor JB and Triggle DJ eds ADME-Tox Approaches. Japan: Pfzer Inc. Elsevier Ltd
    • Sugano K. (2007). Artifcial membrane technologies to assess transfer and permeation of drugs in drug discovery. In: Taylor JB and Triggle DJ, eds. Comprehensive Medicinal Chemistry II, Volume 5: ADME-Tox Approaches. Japan: Pfzer Inc., Elsevier Ltd, 449
    • (2007) Comprehensive Medicinal Chemistry II , vol.5 , pp. 449
    • Sugano, K.1
  • 62
    • 0029924333 scopus 로고    scopus 로고
    • Comparative study on xanthan gum and hydroxypropylmethyl cellulose as matrices for controlled-release drug delivery I. Compaction and in vitro drug release behaviour
    • DOI 10.1016/0378-5173(95)04355-1
    • Talukdar MM, Michoel A, Rombaut P, Kinget R. 1996. Comparative study on xanthan gum and hydroxypropylmethylcellulose as matrices for controlled-release drug delivery. I. Compaction and in vitro drug release behaviour. Int J Pharm, 129, 233-241. (Pubitemid 26098739)
    • (1996) International Journal of Pharmaceutics , vol.129 , Issue.1-2 , pp. 233-241
    • Talukdar, M.M.1    Michoel, A.2    Rombaut, P.3    Kinget, R.4
  • 63
    • 0035693963 scopus 로고    scopus 로고
    • Delivery of neurotrophic factors to the central nervous system: Pharmacokinetic considerations
    • Torne RG, Frey WH II. 2001. Delivery of neurotrophic factors to the central nervous system: Pharmacokinetic considerations. Clin Pharmacokinet, 40(12), 907-946.
    • (2001) Clin Pharmacokinet , vol.40 , Issue.12 , pp. 907-946
    • Torne, R.G.1    Frey, I.I.W.H.2
  • 64
    • 1142285515 scopus 로고    scopus 로고
    • Evaluation of xanthan and highly substituted galactomannan from M. scabrella as a sustained release matrix
    • DOI 10.1016/j.ijpharm.2003.11.011
    • Ughini F, Andreazza IF, Ganter JLMS, Bresolin TMB. 2004. Evaluation of xanthan and highly substituted galactomannan from M. scabrella as a sustained release matrix. Int J Pharm, 271, 197-205 (Pubitemid 38210097)
    • (2004) International Journal of Pharmaceutics , vol.271 , Issue.1-2 , pp. 197-205
    • Ughini, F.1    Andreazza, I.F.2    Ganter, J.L.M.S.3    Bresolin, T.M.B.4
  • 66
    • 22544482035 scopus 로고    scopus 로고
    • Early alteration in bone metabolism in epileptic children receiving carbamazepine monotherapy owing to the induction of hepatic drug-metabolizing enzymes
    • Voudris KA, Attilakos A, Katsarou E, Garouf A, Dimou S, Skardoutsou A, Mastroyianni S. 2005. Early alteration in bone metabolism in epileptic children receiving carbamazepine monotherapy owing to the induction of hepatic drug-metabolizing enzymes. J Child Neurol, 20(6), 513-516. (Pubitemid 41015247)
    • (2005) Journal of Child Neurology , vol.20 , Issue.6 , pp. 513-516
    • Voudris, K.A.1    Attilakos, A.2    Katsarou, E.3    Garoufi, A.4    Dimou, S.5    Skardoutsou, A.6    Mastroyianni, S.7
  • 67
    • 33645731771 scopus 로고    scopus 로고
    • Preliminary brain-targeting studies on intranasal mucoadhesive microemulsions of sumatriptan
    • Vyas TK, Babbar AK, Sharma RK, Singh S, Misra A. 2006. Preliminary brain-targeting studies on intranasal mucoadhesive microemulsions of sumatriptan. AAPS Pharm Sci Tech,7(1), E8
    • (2006) AAPS Pharm Sci Tech , vol.7 , Issue.1
    • Vyas, T.K.1    Babbar, A.K.2    Sharma, R.K.3    Singh, S.4    Misra, A.5
  • 68
    • 0002021428 scopus 로고
    • General principles: Experimental selection, quantifcation and evaluation of anti-epileptic drugs
    • Levy RH, Mattson RH, Meldrum BS, eds New York: Raven press Ltd.
    • White HS, Woodhead JH, Franklin MR, Swingered EA, Wolf HH. (1995). General principles: Experimental selection, quantifcation and evaluation of anti-epileptic drugs. In: Levy RH, Mattson RH, Meldrum BS, eds. Anti-epileptic drugs. New York: Raven press Ltd., 99-122.
    • (1995) Anti-epileptic Drugs , pp. 99-122
    • White, H.S.1    Woodhead, J.H.2    Franklin, M.R.3    Swingered, E.A.4    Wolf, H.H.5
  • 69
    • 0028863335 scopus 로고
    • Physicochemical characterization of parenteral lipid emulsion: Infuence of cosurfactants on focculation and coalescence
    • Yamaguchi T, Nishizaki K, Itai S, Hayashi H, Ohshima H. 1995. Physicochemical characterization of parenteral lipid emulsion: infuence of cosurfactants on focculation and coalescence. Pharm Res; 12, 1273-1278.
    • (1995) Pharm Res; , vol.12 , pp. 1273-1278
    • Yamaguchi, T.1    Nishizaki, K.2    Itai, S.3    Hayashi, H.4    Ohshima, H.5
  • 70
    • 1842789813 scopus 로고    scopus 로고
    • Preparation of nimodipine-loaded microemulsion for intranasal delivery and evaluation on the targeting efficiency to the brain
    • DOI 10.1016/j.ijpharm.2004.01.039, PII S0378517304000870
    • Zhang Q, Jiang X, Jiang W, Lu W, Su L, Shi Z. 2004. Preparation of nimodipine-loaded microemulsion for intranasal delivery and evaluation on the targeting efciency to the brain. Int J Pharm, 275, 85-96. (Pubitemid 38481522)
    • (2004) International Journal of Pharmaceutics , vol.275 , Issue.1-2 , pp. 85-96
    • Zhang, Q.1    Jiang, X.2    Jiang, W.3    Lu, W.4    Su, L.5    Shi, Z.6


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