TRPV4 and AQP4 channels synergistically regulate cell volume and calcium homeostasis in retinal müller glia

Journal of Neuroscience

Volumn 35, Issue 39, 2015, Pages 13525-13537

  Jo, Andrew O ^a   Ryskamp, Daniel A ^a,b   Phuong, Tam T T ^a   Verkman, Alan S ^c   Yarishkin, Oleg ^a   Macaulay, Nanna ^d   Križaj, David ^a,b  

^a John Moran Eye Centre   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Aquaporin 4; Muller cell; Osmoregulation; Retina; Swelling; TRPV4

Indexed keywords

AQUAPORIN 4; TRANSIENT RECEPTOR POTENTIAL CHANNEL 4; VANILLOID RECEPTOR 4; AQP4 PROTEIN, MOUSE; CALCIUM; HC-067047; INWARDLY RECTIFYING POTASSIUM CHANNEL; KCNJ10 (CHANNEL); LEUCINE; MORPHOLINE DERIVATIVE; N-(1-((4-(2-(((2,4-DICHLOROPHENYL)SULFONYL)AMINO)-3-HYDROXYPROPANOYL)-1-PIPERAZINYL)CARBONYL)-3-METHYLBUTYL)-1-BENZOTHIOPHENE-2-CARBOXAMIDE; PYRROLE DERIVATIVE; SULFONAMIDE; TRPV4 PROTEIN, MOUSE; VANILLOID RECEPTOR; WATER;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM SIGNALING; CELL SWELLING; CELL VOLUME; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLIA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MACROGLIA; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; OSMOREGULATION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL SIZE; CYTOLOGY; DRUG EFFECTS; GENETICS; HOMEOSTASIS; KNOCKOUT MOUSE; METABOLISM; OOCYTE; PHYSIOLOGY; RETINA; ULTRASTRUCTURE; XENOPUS;

ANIMALS; AQUAPORIN 4; CALCIUM; CALCIUM SIGNALING; CELL SIZE; GENE EXPRESSION; HOMEOSTASIS; LEUCINE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MORPHOLINES; NEUROGLIA; OOCYTES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PYRROLES; RETINA; SULFONAMIDES; TRPV CATION CHANNELS; WATER; XENOPUS;

EID: 84942874942     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1987-15.2015     Document Type: Article

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