Red blood cells affect the margination of microparticles in synthetic microcapillaries and intravital microcirculation as a function of their size and shape

Journal of Controlled Release

Volumn 217, Issue , 2015, Pages 263-272

  D'Apolito, Rosa ^a,c   Tomaiuolo, Giovanna ^a,c   Taraballi, Francesca ^b   Minardi, Silvia ^b   Kirui, Dickson ^b,d   Liu, Xuewu ^b   Cevenini, Armando ^a   Palomba, Roberto ^b   Ferrari, Mauro ^b   Salvatore, Francesco ^a,c   Tasciotti, Ennio ^b   Guido, Stefano ^a,c  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^c CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

^d Naval Medical Research Unit   (United States)

Author keywords

Drug delivery; Margination; Micro particles; Microcirculation; Red blood cells; Shape; Size

Indexed keywords

ADHESION; BLOOD; CYTOLOGY; DRUG DELIVERY; MICROCIRCULATION;

MARGINATION; MICRO PARTICLES; RED BLOOD CELL; SHAPE; SIZE;

CELLS;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL WALL; CELL FREE SYSTEM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ERYTHROCYTE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRAVITAL CONFOCAL MICROSCOPY; MEMBRANE MICROPARTICLE; MICROCIRCULATION; MICROFLUIDICS; MOUSE; NONHUMAN; NORMAL HUMAN; PARTICLE SIZE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; ZETA POTENTIAL; ANIMAL; CAPILLARY; CHEMISTRY; PHYSIOLOGY; TRANSGENIC MOUSE;

LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMALS; CAPILLARIES; ERYTHROCYTES; HUMANS; LACTIC ACID; MICE, TRANSGENIC; MICROCIRCULATION; MICROFLUIDICS; MICROSCOPY, CONFOCAL; PARTICLE SIZE; POLYGLYCOLIC ACID;

EID: 84942872040     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.09.013     Document Type: Article

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