Systematic and molecular basis of the antibacterial action of quinoxaline 1,4-di-noxides against Escherichia coli

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Cheng, Guyue ^a   Li, Bei ^a   Wang, Chenxi ^a   Zhang, Hongfei ^a   Liang, Guixia ^a   Weng, Zhifei ^a   Hao, Haihong ^a   Wang, Xu ^a   Liu, Zhenli ^a   Dai, Menghong ^a   Wang, Yulian ^a   Yuan, Zonghui ^a  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL DNA; CIADOX; ENROFLOXACIN; FREE RADICAL; MEQUINDOX; MESSENGER RNA; OLAQUINDOX; QUINOXALINE 1,4 DI N OXIDE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SCAVENGER; UNCLASSIFIED DRUG; XANTHINE OXIDASE; QUINOXALINE DERIVATIVE; TIRAPAZAMINE; TRIAZINE DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL METABOLISM; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; BIOCHEMICAL ANALYSIS; BROTH DILUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DRUG EXPOSURE; DRUG RESEARCH; DRUG STRUCTURE; ELECTRON SPIN RESONANCE; ESCHERICHIA COLI; MICROARRAY ANALYSIS; MICROBIAL MORPHOLOGY; MINIMUM BACTERICIDAL CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OXIDATIVE STRESS; PROTEOMICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; TRANSCRIPTOMICS; AGONISTS; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIAL SENSITIVITY TEST; MOLECULAR GENETICS; OXIDATION REDUCTION REACTION; PROTEIN SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; CELL SURVIVAL; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE ANNOTATION; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN BIOSYNTHESIS; PROTEOMICS; QUINOXALINES; REACTIVE OXYGEN SPECIES; SOS RESPONSE (GENETICS); STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZINES;

EID: 84942848328     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0136450     Document Type: Article

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