Lycopene protects against hypoxia/reoxygenation injury by alleviating ER stress induced apoptosis in neonatal mouse cardiomyocytes

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Xu, Jiqian ^a   Hu, Houxiang ^a   Chen, Bin ^a   Yue, Rongchuan ^a   Zhou, Zhou ^b   Liu, Yin ^c   Zhang, Shuang ^a   Xu, Lei ^a   Wang, Huan ^a   Yu, Zhengping ^b  

^a AFFILIATED HOSPITAL OF NORTH SICHUAN MEDICAL COLLEGE   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ADENYLATE KINASE; CASPASE 12; CASPASE 3; CHOLECYSTOKININ OCTAPEPTIDE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; LYCOPENE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; THAPSIGARGIN; X BOX BINDING PROTEIN 1; ANTIOXIDANT; CAROTENOID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE;

ACUTE HEART INFARCTION; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HYPOXIA; MOUSE; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REOXYGENATION; REPERFUSION INJURY; SUDDEN CARDIAC DEATH; UPREGULATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CARDIAC MUSCLE CELL; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; ENZYME ACTIVATION; METABOLISM;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; APOPTOSIS; BLOTTING, WESTERN; CAROTENOIDS; CELLS, CULTURED; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HYPOXIA; MICE; MICE, INBRED C57BL; MYOCYTES, CARDIAC; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY;

EID: 84942846115     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0136443     Document Type: Article

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